FI913101A - Foerfarande foer framstaellning av blandningar av polysackarider med laog molekylvikt och anvaendning av dessa. - Google Patents

Foerfarande foer framstaellning av blandningar av polysackarider med laog molekylvikt och anvaendning av dessa. Download PDF

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Publication number
FI913101A
FI913101A FI913101A FI913101A FI913101A FI 913101 A FI913101 A FI 913101A FI 913101 A FI913101 A FI 913101A FI 913101 A FI913101 A FI 913101A FI 913101 A FI913101 A FI 913101A
Authority
FI
Finland
Prior art keywords
polysackarider
molekylvikt
blandningar
dessa
foerfarande foer
Prior art date
Application number
FI913101A
Other languages
English (en)
Other versions
FI104490B (fi
FI913101A0 (fi
Inventor
Roger Debrie
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9398013&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI913101(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of FI913101A0 publication Critical patent/FI913101A0/fi
Publication of FI913101A publication Critical patent/FI913101A/fi
Application granted granted Critical
Publication of FI104490B publication Critical patent/FI104490B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
FI913101A 1990-06-26 1991-06-25 Menetelmä terapeuttisesti käyttökelpoisten sulfatoitujen polysakkaridiseosten valmistamiseksi FI104490B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9008013A FR2663639B1 (fr) 1990-06-26 1990-06-26 Melanges de polysaccharides de bas poids moleculaires procede de preparation et utilisation.
FR9008013 1990-06-26

Publications (3)

Publication Number Publication Date
FI913101A0 FI913101A0 (fi) 1991-06-25
FI913101A true FI913101A (fi) 1991-12-27
FI104490B FI104490B (fi) 2000-02-15

Family

ID=9398013

Family Applications (1)

Application Number Title Priority Date Filing Date
FI913101A FI104490B (fi) 1990-06-26 1991-06-25 Menetelmä terapeuttisesti käyttökelpoisten sulfatoitujen polysakkaridiseosten valmistamiseksi

Country Status (26)

Country Link
US (1) US5389618A (fi)
JP (1) JP3287363B2 (fi)
KR (1) KR0185586B1 (fi)
AT (1) AT398976B (fi)
AU (1) AU643531B2 (fi)
BE (1) BE1006827A3 (fi)
CA (1) CA2045433C (fi)
CH (1) CH682236A5 (fi)
DK (1) DK176524B1 (fi)
ES (1) ES2036922B9 (fi)
FI (1) FI104490B (fi)
FR (1) FR2663639B1 (fi)
GB (1) GB2245898B (fi)
GR (1) GR1000763B (fi)
HU (1) HU210925B (fi)
IE (1) IE66341B1 (fi)
IL (1) IL98604A (fi)
IT (1) IT1248557B (fi)
LU (1) LU87957A1 (fi)
MX (1) MX25829A (fi)
NL (1) NL194947C (fi)
NO (1) NO304991B1 (fi)
NZ (1) NZ238691A (fi)
PT (1) PT98102B (fi)
SE (1) SE506267C2 (fi)
ZA (1) ZA914869B (fi)

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US5849721A (en) * 1992-02-07 1998-12-15 Rhone-Poulenc Rorer S.A. Sulfated polysaccharides obtained from heparin, preparation process, pharmaceutical composition and use thereof
US5801162A (en) * 1993-09-30 1998-09-01 Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) Dermatan sulfate compositions and antithrombotic compositions containing same
CA2370539C (en) 1999-04-23 2009-01-06 Massachusetts Institute Of Technology System and method for notating polymers
AU782661B2 (en) * 1999-06-30 2005-08-18 Hamilton Civic Hospitals Research Development, Inc. Heparin compositions that inhibit clot associated coagulation factors
JP4897991B2 (ja) * 1999-07-23 2012-03-14 ラボラトリオス ファルマセウティコス ロビ ソシエダッド アノニマ 超低分子量ヘパリン組成物
AU1594801A (en) * 1999-11-12 2001-06-06 Emisphere Technologies, Inc. Liquid heparin formulation
US6608042B2 (en) 2000-03-28 2003-08-19 Aventis Pharma, S.A. Pharmaceutical compositions containing oligosaccharides, the novel oligosaccharides and preparation thereof
US6969705B2 (en) 2000-07-21 2005-11-29 Aventis Pharma S.A. Compositions of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
CZ2003961A3 (cs) * 2000-09-08 2003-10-15 Hamilton Civic Hospitals Research Development, Inc. Farmaceutický prostředek k inhibici nebo prevenci tvorby či aktivity thrombinu
ES2238383T3 (es) 2000-12-16 2005-09-01 Aventis Pharma Deutschland Gmbh Uso de heparina de bajo peso molecular para el tratamiento de la osteoartrosis.
DE10141106A1 (de) * 2001-08-22 2003-03-13 Aventis Pharma Gmbh Verwendung von Heparinoid-Derivaten zur Behandlung und Diagnose von mit Heparinoiden behandelbaren Erkrankungen
JP2005505537A (ja) * 2001-08-28 2005-02-24 レオ・ファーマ・アクティーゼルスカブ 低分子量ヘパリンと低分子量デルマタン硫酸とを含む抗血栓組成物
US7084118B2 (en) 2002-02-22 2006-08-01 Genentech, Inc. Combination treatment with t-PA variant and low molecular weight heparin
EP1518120A4 (en) * 2002-03-11 2008-08-13 Momenta Pharmaceuticals Inc ANALYSIS OF SULFATE POLYSACCHARIDES
US20030236221A1 (en) * 2002-06-20 2003-12-25 Chemi Spa Process for the preparation of esters of heparin
EP1375524B1 (en) * 2002-06-20 2007-03-07 CHEMI S.p.A. Process for the preparation of esters of heparin
FR2844808B1 (fr) * 2002-09-23 2005-02-25 Aventis Pharma Sa Methode de determination de groupements specifiques constituant les heparines ou les heparines de bas poids moleculaire
US20040265943A1 (en) * 2002-09-23 2004-12-30 Aventis Pharma S.A. Method for quantitatively determining specific groups constituting heparins or low molecular weight heparins
US20040171819A1 (en) * 2002-10-10 2004-09-02 Aventis Pharma S.A. Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
EP1587408A4 (en) * 2002-12-20 2007-09-05 Momenta Pharmaceuticals Inc GLYCAN MARKER FOR DIAGNOSIS AND MONITORING OF DISEASES
KR20060052692A (ko) * 2003-06-05 2006-05-19 센텔리옹 에스아에스 고콜레스테롤혈증 또는 당뇨병과 관련된 혈관형성 결함을치료하기 위한 섬유모세포 성장 인자를 코딩하는플라스미드
US7956046B2 (en) 2003-07-24 2011-06-07 Aventis Pharma S.A. Oligosaccharide mixtures derived from heparin, preparation thereof and pharmaceutical compositions containing them
ITMI20031679A1 (it) * 2003-08-29 2005-02-28 Opocrin Spa Processo per la produzione di eparine a basso peso
US20050186679A1 (en) * 2004-02-24 2005-08-25 Christian Viskov Method for determining specific groups constituting heparins or low molecular weight heparins
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AU2007267561B2 (en) 2006-05-25 2012-05-17 Momenta Pharmaceuticals, Inc. Low molecular weight heparin composition and uses thereof
US8101733B1 (en) 2006-06-27 2012-01-24 Momenta Pharmaceuticals, Inc. Methods of evaluating mixtures of polysaccharides
US7790466B1 (en) 2007-01-26 2010-09-07 Momenta Pharmaceuticals, Inc. Evaluating mixtures of low molecular weight heparins by chain profiles or chain mapping
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FR2912409B1 (fr) * 2007-02-14 2012-08-24 Sanofi Aventis Heparines de bas poids moleculaire comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine leur procede de preparation,leur utilisation
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EP2283045A1 (en) * 2008-05-20 2011-02-16 Crystal Clear Partnership Separation of polysaccharides by charge density gradient
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CN102791742B (zh) * 2010-01-19 2014-12-24 动量制药公司 评价肝素制剂
CN102792158B (zh) 2011-01-28 2013-07-10 杭州九源基因工程有限公司 一种基于毛细管电泳的依诺肝素钠精细结构测定方法
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CN102603925B (zh) * 2012-03-21 2013-12-11 东营天东制药有限公司 一种由粗品肝素钠直接生产依诺肝素钠的方法
CN102603926B (zh) * 2012-03-27 2014-04-30 烟台东诚生化股份有限公司 一种高效价肝素钠制备新工艺
CN102633908A (zh) * 2012-05-02 2012-08-15 雷晓刚 一种高品质超低分子量肝素的制备方法
RU2512768C1 (ru) * 2012-12-18 2014-04-10 Федеральное бюджетное учреждение "Государственный институт кровезаменителей и медицинских препаратов (ФБУ "ГИКиМП") Способ получения низкомолекулярного гепарина
CN103145868B (zh) * 2013-01-07 2015-09-16 中国科学院昆明植物研究所 一种低分子量糖胺聚糖衍生物及其药物组合物和其制备方法与应用
CN103175925B (zh) * 2013-03-20 2014-12-03 山东辰中生物制药有限公司 依诺肝素钠生产过程中肝素苄基酯的酯化率的检测方法
CN103214591B (zh) * 2013-04-12 2015-11-04 中国科学院昆明植物研究所 一种含末端2,5-脱水塔罗糖或其衍生物的低分子量糖胺聚糖衍生物
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FR2482611B1 (fr) * 1980-05-14 1986-03-07 Pharmindustrie Nouveaux polysaccharides sulfates, procedes pour leur preparation et leur utilisation comme medicaments
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DK196886D0 (da) * 1986-04-30 1986-04-30 Novo Industri As Fremstilling af polysaccharider
IT1213384B (it) * 1986-11-24 1989-12-20 Lab Derivati Organici Mediolan Processo per la preparazione controllata di gilcosaminoglicani a basso peso molecolare.
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Also Published As

Publication number Publication date
BE1006827A3 (fr) 1995-01-03
CA2045433C (fr) 2002-07-30
GB9113589D0 (en) 1991-08-14
CH682236A5 (fi) 1993-08-13
PT98102A (pt) 1992-03-31
SE506267C2 (sv) 1997-11-24
GR1000763B (el) 1992-12-30
IE912216A1 (en) 1992-01-01
AU643531B2 (en) 1993-11-18
IE66341B1 (en) 1995-12-27
DK124391D0 (da) 1991-06-25
ES2036922A1 (es) 1993-06-01
IT1248557B (it) 1995-01-19
NO912485L (no) 1991-12-27
IL98604A0 (en) 1992-07-15
FI104490B (fi) 2000-02-15
ES2036922B1 (es) 1994-03-01
HUT57796A (en) 1991-12-30
SE9101957D0 (sv) 1991-06-25
IL98604A (en) 1998-08-15
AU7928891A (en) 1992-01-02
GB2245898A (en) 1992-01-15
PT98102B (pt) 1998-11-30
SE9101957L (sv) 1991-12-27
FR2663639B1 (fr) 1994-03-18
CA2045433A1 (fr) 1991-12-27
ITMI911757A0 (it) 1991-06-26
MX25829A (es) 1993-10-01
NZ238691A (en) 1992-07-28
LU87957A1 (fr) 1993-01-15
ITMI911757A1 (it) 1992-12-26
US5389618A (en) 1995-02-14
GR910100270A (en) 1992-08-25
KR0185586B1 (ko) 1999-04-01
AT398976B (de) 1995-02-27
ES2036922B9 (es) 2012-07-30
NL194947B (nl) 2003-04-01
NL194947C (nl) 2003-08-04
NL9101049A (nl) 1992-01-16
DK176524B1 (da) 2008-07-14
GB2245898B (en) 1993-10-06
DK124391A (da) 1991-12-27
FR2663639A1 (fr) 1991-12-27
JP3287363B2 (ja) 2002-06-04
JPH04226101A (ja) 1992-08-14
NO304991B1 (no) 1999-03-15
ATA128191A (de) 1994-07-15
NO912485D0 (no) 1991-06-25
ZA914869B (en) 1992-04-29
HU210925B (en) 1995-09-28
KR920000792A (ko) 1992-01-29
FI913101A0 (fi) 1991-06-25

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