US5612034A
(en)
*
|
1990-10-03 |
1997-03-18 |
Redcell, Inc. |
Super-globuling for in vivo extended lifetimes
|
EP0802798A1
(en)
*
|
1994-02-23 |
1997-10-29 |
Chiron Corporation |
Method and compositions for increasing the serum half-life of pharmacologically active agents
|
FR2726471B1
(fr)
*
|
1994-11-07 |
1997-01-31 |
Pf Medicament |
Procede pour ameliorer l'immunogenicite d'un compose immunogene ou d'un haptene et application a la preparation de vaccins
|
EP1619250B1
(en)
*
|
1996-01-08 |
2009-11-25 |
Genentech, Inc. |
OB receptor variant and ligands
|
US20050019325A1
(en)
|
1996-01-08 |
2005-01-27 |
Carter Paul J. |
WSX receptor agonist antibodies
|
US7074397B1
(en)
|
1996-01-08 |
2006-07-11 |
Genentech, Inc. |
Method for enhancing proliferation or differentiation of a cell using ob protein
|
US6541604B1
(en)
|
1996-01-08 |
2003-04-01 |
Genentech, Inc. |
Leptin receptor having a WSX motif
|
CA2330611A1
(en)
|
1998-05-22 |
1999-12-02 |
The Board Of Trustees Of The Leland Stanford Junior University |
Bifunctional molecules and therapies based thereon
|
WO2000022112A1
(en)
|
1998-10-13 |
2000-04-20 |
The University Of Georgia Research Foundation, Inc. |
Stabilized bioactive peptides and methods of identification, synthesis and use
|
US20030190740A1
(en)
|
1998-10-13 |
2003-10-09 |
The University Of Georgia Research Foundation, Inc |
Stabilized bioactive peptides and methods of identification, synthesis, and use
|
US7220552B1
(en)
|
1999-11-19 |
2007-05-22 |
The Board Of Trustees Of The Leland Stanford Junior University |
Bifunctional molecules and their use in the disruption of protein-protein interactions
|
US6887842B1
(en)
|
1999-11-19 |
2005-05-03 |
The Board Of Trustees Of The Leland Stanford Junior University |
Modulating a pharmacokinetic property of a drug by administering a bifunctional molecule containing the drug
|
WO2001035748A1
(en)
*
|
1999-11-19 |
2001-05-25 |
The Board Of Trustees Of The Leland Stanford Junior University |
Bifunctional molecules having modulated pharmacokinetic properties and therapies based thereon
|
EP1229924A4
(en)
|
1999-11-19 |
2004-12-15 |
Univ Leland Stanford Junior |
TARGETED BIFUNCTIONAL MOLECULES AND THERAPIES THEREFORE
|
EP1757311B1
(en)
|
1999-12-24 |
2009-02-11 |
Genentech, Inc. |
Methods and compositions for prolonging elimination half-times of bioactive compounds
|
JP2003518075A
(ja)
*
|
1999-12-24 |
2003-06-03 |
ジェネンテック・インコーポレーテッド |
生理活性化合物の消失半減期延長のための方法及び組成物
|
EP1377306A1
(en)
|
2001-03-09 |
2004-01-07 |
Dyax Corp. |
Serum albumin binding moieties
|
US20030157561A1
(en)
*
|
2001-11-19 |
2003-08-21 |
Kolkman Joost A. |
Combinatorial libraries of monomer domains
|
WO2004003019A2
(en)
*
|
2002-06-28 |
2004-01-08 |
Domantis Limited |
Immunoglobin single variant antigen-binding domains and dual-specific constructs
|
EP2075256A2
(en)
|
2002-01-14 |
2009-07-01 |
William Herman |
Multispecific binding molecules
|
EP1536818A2
(en)
|
2002-03-26 |
2005-06-08 |
Dyax Corp. |
Fibrinogen binding moieties
|
EP1837031B1
(en)
|
2002-06-07 |
2009-10-14 |
Waratah Pharmaceuticals, Inc. |
Compositions and methods for treating diabetes
|
US9321832B2
(en)
|
2002-06-28 |
2016-04-26 |
Domantis Limited |
Ligand
|
WO2004041865A2
(en)
|
2002-11-08 |
2004-05-21 |
Ablynx N.V. |
Stabilized single domain antibodies
|
US20060034845A1
(en)
|
2002-11-08 |
2006-02-16 |
Karen Silence |
Single domain antibodies directed against tumor necrosis factor alpha and uses therefor
|
US9320792B2
(en)
|
2002-11-08 |
2016-04-26 |
Ablynx N.V. |
Pulmonary administration of immunoglobulin single variable domains and constructs thereof
|
DE05733048T1
(de)
*
|
2004-04-06 |
2007-05-10 |
Affibody Ab |
Serumalbuminbindende peptidkonjugate zur arzneimittelherstellung
|
KR20120133403A
(ko)
*
|
2004-06-01 |
2012-12-10 |
도만티스 리미티드 |
증강된 혈청 반감기를 가지는 이특이성 융합 항체
|
US7563443B2
(en)
|
2004-09-17 |
2009-07-21 |
Domantis Limited |
Monovalent anti-CD40L antibody polypeptides and compositions thereof
|
KR20070073886A
(ko)
*
|
2004-10-05 |
2007-07-10 |
제넨테크, 인크. |
독성이 감소된 치료제
|
GB0426146D0
(en)
|
2004-11-29 |
2004-12-29 |
Bioxell Spa |
Therapeutic peptides and method
|
JP5185624B2
(ja)
|
2004-12-02 |
2013-04-17 |
ドマンティス リミテッド |
血清アルブミンおよびglp−1またはpyyを標的とする二重特異性抗体
|
CA2589802A1
(en)
*
|
2004-12-02 |
2006-06-08 |
Domantis Limited |
Plad domain peptides with increased serum half life due to conjugation to domain antibodies
|
CA2588892A1
(en)
*
|
2004-12-02 |
2006-06-08 |
Dormantis Limited |
Anti-il-1r1 single domain antibodies and therapeutic uses
|
EP1888640B1
(en)
|
2005-05-18 |
2012-03-14 |
Ablynx N.V. |
Improved nanobodies against tumor necrosis factor-alpha
|
EP1940880A2
(en)
*
|
2005-10-14 |
2008-07-09 |
Novo Nordisk A/S |
Treating diabetes using inhibitors of il-1
|
ATE536369T1
(de)
*
|
2006-10-11 |
2011-12-15 |
Ablynx Nv |
Im wesentlichen ph-wert-unabhängigerweise an serumproteine bindende aminosäuresequenzen, verbindungen, die diese enthalten, und deren verwendung
|
GB0621513D0
(en)
|
2006-10-30 |
2006-12-06 |
Domantis Ltd |
Novel polypeptides and uses thereof
|
US9512236B2
(en)
|
2006-12-19 |
2016-12-06 |
Ablynx N.V. |
Amino acid sequences directed against GPCRS and polypeptides comprising the same for the treatment of GPCR-related diseases and disorders
|
EP2557090A3
(en)
|
2006-12-19 |
2013-05-29 |
Ablynx N.V. |
Amino acid sequences directed against GPCRs and polypeptides comprising the same for the treatment of GPCR-related diseases and disorders
|
WO2008074840A2
(en)
|
2006-12-19 |
2008-06-26 |
Ablynx N.V. |
Amino acid sequences directed against a metalloproteinase from the adam family and polypeptides comprising the same for the treatment of adam-related diseases and disorders
|
AU2008281913B2
(en)
|
2007-07-31 |
2013-11-07 |
Affibody Ab |
New albumin binding compositions, methods and uses
|
EP2535349A1
(en)
|
2007-09-26 |
2012-12-19 |
UCB Pharma S.A. |
Dual specificity antibody fusions
|
AR068767A1
(es)
|
2007-10-12 |
2009-12-02 |
Novartis Ag |
Anticuerpos contra esclerostina, composiciones y metodos de uso de estos anticuerpos para tratar un trastorno patologico mediado por esclerostina
|
WO2009068630A1
(en)
|
2007-11-27 |
2009-06-04 |
Ablynx N.V. |
Immunoglobulin constructs
|
EP2231860B1
(en)
|
2007-12-19 |
2011-10-05 |
Affibody AB |
Polypeptide derived from protein a and able to bind pdgf
|
EP2077272A1
(en)
|
2007-12-21 |
2009-07-08 |
Affibody AB |
Polypeptide libraries with a predetermined scaffold
|
US9187535B2
(en)
|
2007-12-19 |
2015-11-17 |
Affibody Ab |
Polypeptide derived from protein A and able to bind PDGF
|
EP2072525A1
(en)
|
2007-12-21 |
2009-06-24 |
Affibody AB |
New polypeptides having affinity for HER2
|
WO2009124931A2
(en)
|
2008-04-07 |
2009-10-15 |
Ablynx Nv |
Amino acid sequences directed against the notch pathways and uses thereof
|
US9212226B2
(en)
|
2008-05-16 |
2015-12-15 |
Ablynx N.V. |
Amino acid sequences directed against CXCR4 and other GPCRs and compounds comprising the same
|
DK2285408T3
(en)
|
2008-06-05 |
2019-02-04 |
Ablynx Nv |
AMINO ACID SEQUENCES AGAINST COATING PROTEINS IN A VIRUS AND POLYPEPTIDES INCLUDING THESE FOR TREATMENT OF VIRUSAL DISEASES
|
DK2334705T3
(en)
|
2008-09-26 |
2017-03-27 |
Ucb Biopharma Sprl |
BIOLOGICAL PRODUCTS
|
WO2010056550A1
(en)
|
2008-10-29 |
2010-05-20 |
Wyeth Llc |
Methods for purification of single domain antigen binding molecules
|
CN102271707B
(zh)
|
2008-10-29 |
2015-04-08 |
阿布林克斯公司 |
单域抗原结合性分子的制剂
|
US9260508B2
(en)
|
2008-12-19 |
2016-02-16 |
Ablynx N.V. |
Method for generation of immunoglobulin sequences
|
US20120165650A1
(en)
|
2010-12-22 |
2012-06-28 |
General Electric Company |
Her2 binders
|
US8748581B2
(en)
|
2009-04-10 |
2014-06-10 |
Ablynx N.V. |
Anti-IL-6R polypeptides and pharmaceutical compositions thereof
|
BRPI1016055A2
(pt)
|
2009-04-27 |
2016-05-10 |
Novartis Ag |
composição e métodos de uso para anticorpos terapêuticos específicos para a subunidade beta i do receptor de il-12
|
SI2424895T1
(en)
|
2009-04-27 |
2018-01-31 |
Novartis Ag |
Ingredients and procedures for increasing muscle growth
|
SG176095A1
(en)
|
2009-06-05 |
2011-12-29 |
Ablynx Nv |
Monovalent, bivalent and trivalent anti human respiratory syncytial virus (hrsv) nanobody constructs for the prevention and/or treatment of respiratory tract infections
|
WO2011029823A1
(en)
|
2009-09-09 |
2011-03-17 |
Novartis Ag |
Monoclonal antibody reactive with cd63 when expressed at the surface of degranulated mast cells
|
GB201005063D0
(en)
|
2010-03-25 |
2010-05-12 |
Ucb Pharma Sa |
Biological products
|
WO2011056124A1
(en)
|
2009-11-04 |
2011-05-12 |
Affibody Ab |
Her3 binding polypeptides
|
EP2507262A1
(en)
|
2009-11-30 |
2012-10-10 |
Ablynx N.V. |
Improved amino acid sequences directed against human respiratory syncytial virus (hrsv) and polypeptides comprising the same for the prevention and/or treatment of respiratory tract infections
|
EP2513145B1
(en)
|
2009-12-14 |
2018-01-24 |
Ablynx N.V. |
Single variable domain antibodies against ox40l, constructs and therapeutic use
|
KR20120107122A
(ko)
|
2009-12-22 |
2012-09-28 |
노파르티스 아게 |
치료법에서 사용하기 위한 4가 cd47―항체 불변 영역 융합 단백질
|
WO2011083140A1
(en)
|
2010-01-08 |
2011-07-14 |
Ablynx Nv |
Immunoglobulin single variable domain directed against human cxcr4
|
US9120855B2
(en)
|
2010-02-10 |
2015-09-01 |
Novartis Ag |
Biologic compounds directed against death receptor 5
|
US8937164B2
(en)
|
2010-03-26 |
2015-01-20 |
Ablynx N.V. |
Biological materials related to CXCR7
|
KR20130093470A
(ko)
*
|
2010-04-30 |
2013-08-22 |
가부시키가이샤산와카가쿠켄큐쇼 |
생리활성 물질 등의 생체 내 안정성 향상을 위한 펩티드 및 생체 내 안정성이 향상된 생리활성 물질
|
EP3546483A1
(en)
|
2010-05-20 |
2019-10-02 |
Ablynx N.V. |
Biological materials related to her3
|
JP5827994B2
(ja)
|
2010-07-09 |
2015-12-02 |
アフィボディ・アーベー |
ポリペプチド
|
CN103370083B
(zh)
|
2010-09-28 |
2016-11-16 |
艾米琳制药有限责任公司 |
具有增强的作用持续时间的工程化多肽
|
EP2621953B1
(en)
|
2010-09-30 |
2017-04-05 |
Ablynx N.V. |
Biological materials related to c-met
|
CN103154037A
(zh)
|
2010-10-05 |
2013-06-12 |
诺瓦提斯公司 |
抗IL12Rβ1抗体及它们在治疗自身免疫病和炎性疾病中的用途
|
EP2638068B1
(en)
|
2010-11-08 |
2018-12-26 |
Novartis AG |
Cxcr2 binding polypeptides
|
ES2758352T3
(es)
|
2010-11-26 |
2020-05-05 |
Molecular Partners Ag |
Proteínas de repetición diseñadas que se une a la seroalbúmina
|
CA2827170A1
(en)
|
2011-02-11 |
2012-08-16 |
David M. Hilbert |
Monovalent and multivalent multispecific complexes and uses thereof
|
EP2691418A1
(en)
|
2011-03-28 |
2014-02-05 |
Ablynx N.V. |
Bispecific anti-cxcr7 immunoglobulin single variable domains
|
UA117218C2
(uk)
|
2011-05-05 |
2018-07-10 |
Мерк Патент Гмбх |
Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f
|
EP2707391B1
(en)
|
2011-05-13 |
2017-11-08 |
Gamamabs Pharma |
Antibodies against her3
|
CN108329391A
(zh)
|
2011-05-27 |
2018-07-27 |
埃博灵克斯股份有限公司 |
使用rankl结合肽抑制骨质吸收
|
JP2014519338A
(ja)
|
2011-06-16 |
2014-08-14 |
ノバルティス アーゲー |
治療薬として使用される可溶性タンパク質
|
RU2014101707A
(ru)
|
2011-06-22 |
2015-07-27 |
Инсерм (Энститю Насьональ Де Ля Сантэ Э Де Ля Решерш Медикаль) |
АНТИ-Axl АНТИТЕЛА И ИХ ПРИМЕНЕНИЕ
|
EP2723376B1
(en)
|
2011-06-22 |
2018-12-05 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti-axl antibodies and uses thereof
|
JP2014525736A
(ja)
|
2011-06-23 |
2014-10-02 |
アブリンクス エン.ヴェー. |
IgEに対する免疫グロブリン単一可変ドメイン
|
HUE040276T2
(hu)
|
2011-07-01 |
2019-02-28 |
Novartis Ag |
Eljárás metabolikus rendellenességek kezelésére
|
EP2747782B1
(en)
|
2011-09-23 |
2018-01-17 |
Ablynx NV |
Prolonged inhibition of interleukin-6 mediated signaling
|
SG10201504605RA
(en)
|
2011-09-23 |
2015-07-30 |
Technophage Investigação E Desenvolvimento Em Biotecnologia Sa |
Anti-Tumor Necrosis Factor-Alpha Agents And Uses Thereof
|
CA2849705A1
(en)
|
2011-09-23 |
2013-03-28 |
Technophage, Investigacao E Desenvolvimento Em Biotecnologia, Sa |
Modified albumin-binding domains and uses thereof to improve pharmacokinetics
|
EP2747783B1
(en)
|
2011-09-30 |
2017-06-14 |
Ablynx N.V. |
Biological materials related to c-met
|
CA2856216C
(en)
|
2011-11-11 |
2021-01-12 |
Ucb Pharma S.A. |
Albumin binding antibodies and binding fragments thereof
|
WO2013126006A1
(en)
|
2012-02-20 |
2013-08-29 |
Swedish Orphan Biovitrum Ab (Publ) |
Polypeptides binding to human complement c5
|
WO2013143890A1
(en)
|
2012-03-28 |
2013-10-03 |
Affibody Ab |
Oral administration
|
JP2020033372A
(ja)
*
|
2012-03-28 |
2020-03-05 |
アフィボディ・アーベー |
経口投与
|
US9328174B2
(en)
|
2012-05-09 |
2016-05-03 |
Novartis Ag |
Chemokine receptor binding polypeptides
|
MX349035B
(es)
|
2012-05-17 |
2017-07-07 |
Extend Biosciences Inc |
Portadores para el suministro mejorado de farmaco.
|
JP6590695B2
(ja)
|
2012-09-25 |
2019-10-16 |
アフィボディ・アーベー |
アルブミン結合ポリペプチド
|
WO2014053586A1
(en)
|
2012-10-05 |
2014-04-10 |
Affibody Ab |
Her3 binding polypeptides
|
PL2912054T3
(pl)
|
2012-10-25 |
2017-11-30 |
Affibody Ab |
Polipeptyd wiążący albuminę
|
JP6396303B2
(ja)
|
2012-10-25 |
2018-09-26 |
アフィボディ・アーベー |
アルブミン結合を含有するタンパク質の分離方法
|
WO2014076179A1
(en)
|
2012-11-14 |
2014-05-22 |
Affibody Ab |
New polypeptide
|
EP2752426A1
(en)
|
2013-01-03 |
2014-07-09 |
Covagen AG |
Human serum albumin binding compounds and fusion proteins thereof
|
WO2015198217A2
(en)
|
2013-02-08 |
2015-12-30 |
Novartis Ag |
Compositions and methods for long-acting antibodies targeting il-17
|
CA3185317A1
(en)
|
2013-02-08 |
2014-08-14 |
Novartis Ag |
Anti-il-17a antibodies and their use in treating autoimmune and inflammatory disorders
|
EP2968587A2
(en)
|
2013-03-13 |
2016-01-20 |
Bristol-Myers Squibb Company |
Fibronectin based scaffold domains linked to serum albumin or a moiety binding thereto
|
WO2014210029A1
(en)
|
2013-06-24 |
2014-12-31 |
Riogin Corporation |
Double binding constructs
|
RU2016108652A
(ru)
|
2013-08-14 |
2017-09-14 |
Новартис Аг |
Способы лечения спорадического миозита с тельцами включений
|
TR201911279T4
(tr)
|
2013-08-28 |
2019-08-21 |
Affibody Ab |
Mutasyona uğramış bir yapı iskelesine sahip polipeptidlerin bağlanması.
|
WO2015028558A1
(en)
|
2013-08-28 |
2015-03-05 |
Swedish Orphan Biovitrum Ab (Publ) |
Stable polypeptides binding to human complement c5
|
US10196455B2
(en)
|
2013-11-07 |
2019-02-05 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Neuregulin allosteric anti-HER3 antibody
|
WO2015091957A1
(en)
|
2013-12-20 |
2015-06-25 |
Affibody Ab |
Engineered albumin binding polypeptide
|
TW201622746A
(zh)
|
2014-04-24 |
2016-07-01 |
諾華公司 |
改善或加速髖部骨折術後身體復原之方法
|
NL2013661B1
(en)
|
2014-10-21 |
2016-10-05 |
Ablynx Nv |
KV1.3 Binding immunoglobulins.
|
US9585934B2
(en)
|
2014-10-22 |
2017-03-07 |
Extend Biosciences, Inc. |
Therapeutic vitamin D conjugates
|
US9789197B2
(en)
|
2014-10-22 |
2017-10-17 |
Extend Biosciences, Inc. |
RNAi vitamin D conjugates
|
WO2016065052A1
(en)
|
2014-10-22 |
2016-04-28 |
Extend Biosciences, Inc. |
Insulin vitamin d conjugates
|
EP3227319B1
(en)
*
|
2014-12-04 |
2019-11-27 |
Novartis AG |
Methods and compositions using klotho variant polypeptides
|
WO2016100803A2
(en)
|
2014-12-19 |
2016-06-23 |
Alexion Pharmaceuticals, Inc. |
Methods of treating tissue calcification
|
BR112017020986A2
(pt)
|
2015-04-02 |
2018-08-14 |
Molecular Partners Ag. |
proteínas de ligação recombinantes e seu uso
|
AU2016239844B2
(en)
|
2015-04-02 |
2021-05-13 |
Ablynx N.V. |
Bispecific CXCR4-CD-4 polypeptides with potent anti-HIV activity
|
RS59376B1
(sr)
|
2015-05-13 |
2019-11-29 |
Ablynx Nv |
Polipeptidi koji regrutuju t-ćelije na bazi tcr-alfa/beta reaktivnosti
|
EP3294319B1
(en)
|
2015-05-13 |
2024-04-24 |
Ablynx NV |
T cell recruiting polypeptides based on cd3 reactivity
|
US10526415B2
(en)
|
2015-05-22 |
2020-01-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Human monoclonal antibodies fragments inhibiting both the Cath-D catalytic activity and its binding to the LRP1 receptor
|
JP6983075B2
(ja)
|
2015-06-02 |
2021-12-17 |
ノヴォ ノルディスク アー/エス |
極性の組換え延長部を有するインスリン
|
JP2018528763A
(ja)
|
2015-07-31 |
2018-10-04 |
リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル |
バイオフィルムの除去のためのペプチドおよび抗体
|
MA43348A
(fr)
|
2015-10-01 |
2018-08-08 |
Novo Nordisk As |
Conjugués de protéines
|
EP3365027B1
(en)
|
2015-10-14 |
2022-03-30 |
Research Institute at Nationwide Children's Hospital |
Hu specific antibodies and their use in inhibiting biofilm
|
KR20180092947A
(ko)
|
2015-10-30 |
2018-08-20 |
더 리전츠 오브 더 유니버시티 오브 캘리포니아 |
형질 전환 성장 인자-베타-반응성 폴리펩티드 및 이의 사용 방법
|
RU2018122255A
(ru)
|
2015-11-27 |
2019-12-19 |
Аблинкс Нв |
Полипептиды, ингибирующие cd40l
|
US11364284B2
(en)
|
2016-06-16 |
2022-06-21 |
Inozyme Pharma, Inc. |
Methods of treating myointimal proliferation
|
WO2018007442A1
(en)
|
2016-07-06 |
2018-01-11 |
Ablynx N.V. |
Treatment of il-6r related diseases
|
BR112019001693A2
(pt)
|
2016-07-29 |
2019-07-02 |
Ct Hospitalier Universitaire Toulouse |
anticorpos direcionados a macrófagos associados a tumores e seus usos
|
WO2018029182A1
(en)
|
2016-08-08 |
2018-02-15 |
Ablynx N.V. |
Il-6r single variable domain antibodies for treatment of il-6r related diseases
|
EP3512880A1
(en)
|
2016-09-15 |
2019-07-24 |
Ablynx NV |
Immunoglobulin single variable domains directed against macrophage migration inhibitory factor
|
US10717772B2
(en)
|
2016-09-22 |
2020-07-21 |
Molecular Partners Ag |
Recombinant binding proteins targeting HER2 and serum albumin, and their uses
|
CA3043515A1
(en)
|
2016-11-16 |
2018-05-24 |
Ablynx Nv |
T cell recruiting polypeptides capable of binding cd123 and tcr alpha/beta
|
WO2018129078A1
(en)
|
2017-01-04 |
2018-07-12 |
Research Institute At Nationwide Children's Hospital |
Dnabii vaccines and antibodies with enhanced activity
|
AU2018206560A1
(en)
|
2017-01-04 |
2019-07-18 |
Research Institute At Nationwide Children's Hospital |
Antibody fragments for the treatment of biofilm-related disorders
|
CN110392697A
(zh)
|
2017-03-02 |
2019-10-29 |
国家医疗保健研究所 |
对nectin-4具有特异性的抗体及其用途
|
JP2020513808A
(ja)
|
2017-03-15 |
2020-05-21 |
リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル |
付随する炎症のない細菌バイオフィルムの破壊のための組成物および方法
|
CN110461359A
(zh)
|
2017-03-24 |
2019-11-15 |
诺华股份有限公司 |
用于预防和治疗心脏病的方法
|
WO2018185131A2
(en)
|
2017-04-05 |
2018-10-11 |
Novo Nordisk A/S |
Oligomer extended insulin-fc conjugates
|
EP3630818A1
(en)
|
2017-06-02 |
2020-04-08 |
Ablynx NV |
Aggrecan binding immunoglobulins
|
MX2019014400A
(es)
|
2017-06-02 |
2020-02-10 |
Merck Patent Gmbh |
Inmunoglobulinas que se unen a adamts.
|
CA3064469A1
(en)
|
2017-06-02 |
2018-12-06 |
Merck Patent Gmbh |
Mmp13 binding immunoglobulins
|
MX2019014397A
(es)
|
2017-06-02 |
2020-02-10 |
Merck Patent Gmbh |
Polipeptidos que enlazan adamts5, mmp13 y agrecano.
|
US20200181271A1
(en)
|
2017-06-28 |
2020-06-11 |
Novartis Ag |
Methods for preventing and treating urinary incontinence
|
CN117327187A
(zh)
|
2017-07-11 |
2024-01-02 |
亚力兄制药公司 |
结合补体成分c5或血清白蛋白的多肽及其融合蛋白
|
CA3096821A1
(en)
|
2017-09-27 |
2019-04-04 |
Inozyme Pharma, Inc. |
Methods of improving cardiovascular function and treating cardiovascular disease using a recombinant ectonucleotide pyrophosphatase phosphodiesterase (npp1)
|
EP3470426A1
(en)
|
2017-10-10 |
2019-04-17 |
Numab Therapeutics AG |
Multispecific antibody
|
CA3075969A1
(en)
|
2017-10-10 |
2019-04-18 |
Numab Therapeutics AG |
Multispecific antibody
|
EP3552631A1
(en)
|
2018-04-10 |
2019-10-16 |
Inatherys |
Antibody-drug conjugates and their uses for the treatment of cancer
|
CA3100007A1
(en)
|
2018-05-14 |
2019-11-21 |
Werewolf Therapeutics, Inc. |
Activatable interleukin-2 polypeptides and methods of use thereof
|
JP2021523741A
(ja)
|
2018-05-14 |
2021-09-09 |
ウェアウルフ セラピューティクス, インコーポレイテッド |
活性化可能なインターロイキン12ポリペプチド及びその使用方法
|
CN113286819A
(zh)
|
2018-08-01 |
2021-08-20 |
感应检查疗法公司 |
抗btn3a抗体及其在治疗癌症或感染性病症中的用途
|
EP3849602A1
(en)
|
2018-09-10 |
2021-07-21 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Combination of her2/neu antibody with heme for treating cancer
|
MX2021003543A
(es)
|
2018-09-27 |
2021-06-23 |
Xilio Dev Inc |
Polipeptidos de citocinas enmascaradas.
|
US20210338783A1
(en)
|
2018-10-05 |
2021-11-04 |
Research Institute At Nationwide Children's Hospital |
Compositions and methods for enzymatic disruption of bacterial biofilms
|
EP3947446A1
(en)
|
2019-03-25 |
2022-02-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Treatment of taupathy disorders by targeting new tau species
|
SG11202112541RA
(en)
|
2019-05-14 |
2021-12-30 |
Werewolf Therapeutics Inc |
Separation moieties and methods and use thereof
|
EA202193345A1
(ru)
|
2019-06-12 |
2022-03-16 |
Новартис Аг |
Антитела к рецептору-1 натрийуретического пептида и способы их применения
|
AU2020311897A1
(en)
|
2019-07-08 |
2022-02-03 |
Research Institute At Nationwide Children's Hospital |
Antibody compositions for disrupting biofilms
|
EP3785726A1
(en)
|
2019-09-02 |
2021-03-03 |
Biotest AG |
Factor viii protein with increased half-life
|
CN114391024A
(zh)
|
2019-09-02 |
2022-04-22 |
生物测试股份公司 |
具有增加的半衰期的因子viii蛋白
|
WO2021058729A1
(en)
|
2019-09-27 |
2021-04-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti-müllerian inhibiting substance type i receptor antibodies and uses thereof
|
EP4034560A1
(en)
|
2019-09-27 |
2022-08-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti-müllerian inhibiting substance antibodies and uses thereof
|
TW202128160A
(zh)
|
2019-10-18 |
2021-08-01 |
美國加利福尼亞大學董事會 |
用於治療病原性血管病症之方法及組合物
|
EP3816185A1
(en)
|
2019-11-04 |
2021-05-05 |
Numab Therapeutics AG |
Multispecific antibody directed against pd-l1 and a tumor-associated antigen
|
EP4072682A1
(en)
|
2019-12-09 |
2022-10-19 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Antibodies having specificity to her4 and uses thereof
|
GB201919061D0
(en)
|
2019-12-20 |
2020-02-05 |
Ucb Biopharma Sprl |
Multi-specific antibody
|
AU2021205639A1
(en)
|
2020-01-10 |
2022-07-14 |
Centre National De La Recherche Scientifique - Cnrs - |
Rspo1 proteins and their use
|
US20230190881A1
(en)
|
2020-02-17 |
2023-06-22 |
Biotest Ag |
Subcutaneous administration of factor viii
|
EP4149558A1
(en)
|
2020-05-12 |
2023-03-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New method to treat cutaneous t-cell lymphomas and tfh derived lymphomas
|
EP3915580A1
(en)
|
2020-05-29 |
2021-12-01 |
Numab Therapeutics AG |
Multispecific antibody
|
US20230265211A1
(en)
|
2020-06-29 |
2023-08-24 |
Inserm (Institut National De La Santé Et De Ls Recherche Médicale) |
Anti-protein s single-domain antibodies and polypeptides comprising thereof
|
EP3988568A1
(en)
|
2020-10-21 |
2022-04-27 |
Numab Therapeutics AG |
Combination treatment
|
WO2022098743A1
(en)
|
2020-11-03 |
2022-05-12 |
Indi Molecular, Inc. |
Compositions, imaging, and therapeutic methods targeting folate receptor 1 (folr1)
|
WO2022098745A1
(en)
|
2020-11-03 |
2022-05-12 |
Indi Molecular, Inc. |
Compositions, delivery systems, and methods useful in tumor therapy
|
PE20231953A1
(es)
|
2020-12-07 |
2023-12-06 |
UCB Biopharma SRL |
Anticuerpos multiespecificos y combinaciones de anticuerpos
|
WO2022130182A1
(en)
|
2020-12-14 |
2022-06-23 |
Novartis Ag |
Reversal binding agents for anti-natriuretic peptide receptor 1 (npr1) antibodies and uses thereof
|
EP4288451A1
(en)
|
2021-02-02 |
2023-12-13 |
Numab Therapeutics AG |
Multispecific antibodies having specificity for ror1 and cd3
|
WO2022171892A1
(en)
|
2021-02-15 |
2022-08-18 |
Affibody Ab |
New her2-binding polypeptide
|
IL305301A
(en)
|
2021-02-19 |
2023-10-01 |
Us Health |
Single domain antibodies neutralizing SARS CoV-2
|
WO2023052541A1
(en)
|
2021-09-30 |
2023-04-06 |
Imcheck Therapeutics |
Combination of an anti-btn3a activating antibody and an il-2 agonist for use in therapy
|
EP4183800A1
(en)
|
2021-11-19 |
2023-05-24 |
Medizinische Hochschule Hannover |
Novel sars-cov-2 neutralizing antibodies
|
TW202405009A
(zh)
|
2022-03-30 |
2024-02-01 |
瑞士商諾華公司 |
使用抗利尿鈉肽受體1(npr1)抗體治療障礙之方法
|
WO2024038095A1
(en)
|
2022-08-16 |
2024-02-22 |
Iome Bio |
NOVEL ANTI-RGMb ANTIBODIES
|
WO2024052503A1
(en)
|
2022-09-08 |
2024-03-14 |
Institut National de la Santé et de la Recherche Médicale |
Antibodies having specificity to ltbp2 and uses thereof
|
WO2024056668A1
(en)
|
2022-09-12 |
2024-03-21 |
Institut National de la Santé et de la Recherche Médicale |
New anti-itgb8 antibodies and its uses thereof
|
WO2024074498A1
(en)
|
2022-10-04 |
2024-04-11 |
Imcheck Therapeutics |
Combination of a btn3a activating antibody, a bcl2 inhibitor and hypomethylating agent for use in treating cancer
|
WO2024083843A1
(en)
|
2022-10-18 |
2024-04-25 |
Confo Therapeutics N.V. |
Amino acid sequences directed against the melanocortin 4 receptor and polypeptides comprising the same for the treatment of mc4r-related diseases and disorders
|