ATE337339T1 - Therapeutische verwendung von smr1 protein und seinen aktiven derivaten - Google Patents
Therapeutische verwendung von smr1 protein und seinen aktiven derivatenInfo
- Publication number
- ATE337339T1 ATE337339T1 AT98912339T AT98912339T ATE337339T1 AT E337339 T1 ATE337339 T1 AT E337339T1 AT 98912339 T AT98912339 T AT 98912339T AT 98912339 T AT98912339 T AT 98912339T AT E337339 T1 ATE337339 T1 AT E337339T1
- Authority
- AT
- Austria
- Prior art keywords
- therapeutic
- well
- molecules
- present
- preventing
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title abstract 5
- 101100533725 Mus musculus Smr3a gene Proteins 0.000 title 1
- 101100149716 Rattus norvegicus Vcsa1 gene Proteins 0.000 title 1
- 101150037481 SMR1 gene Proteins 0.000 title 1
- 101100286750 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) ILV2 gene Proteins 0.000 title 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 2
- 239000003446 ligand Substances 0.000 abstract 2
- 239000011707 mineral Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 108090000244 Rat Proteins Proteins 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 210000003298 dental enamel Anatomy 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 210000001156 gastric mucosa Anatomy 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 230000000762 glandular Effects 0.000 abstract 1
- 210000003734 kidney Anatomy 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 230000035800 maturation Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 210000000496 pancreas Anatomy 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/854—Glands
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/801,405 US6589750B2 (en) | 1997-02-20 | 1997-02-20 | Therapeutic use of the SMR1 protein, the SMR1 maturation products, specifically the QHNPR pentapeptide as well as its biologically active derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE337339T1 true ATE337339T1 (de) | 2006-09-15 |
Family
ID=25181003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98912339T ATE337339T1 (de) | 1997-02-20 | 1998-02-19 | Therapeutische verwendung von smr1 protein und seinen aktiven derivaten |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US6589750B2 (de) |
| EP (2) | EP1007566B1 (de) |
| AT (1) | ATE337339T1 (de) |
| AU (1) | AU6721998A (de) |
| CA (1) | CA2281912A1 (de) |
| DE (1) | DE69835680T2 (de) |
| DK (1) | DK1007566T3 (de) |
| ES (1) | ES2271991T3 (de) |
| PT (1) | PT1007566E (de) |
| WO (1) | WO1998037100A2 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6589750B2 (en) | 1997-02-20 | 2003-07-08 | Institut Pasteur | Therapeutic use of the SMR1 protein, the SMR1 maturation products, specifically the QHNPR pentapeptide as well as its biologically active derivatives |
| DK1185294T3 (da) * | 1999-06-23 | 2005-08-01 | Centre Nat Rech Scient | Peptider til behandling af svækkede interpersonelle og adfærdsmæssige lidelser |
| ATE288763T1 (de) * | 2000-12-22 | 2005-02-15 | Pasteur Institut | Prozess zum screening von molekülen, die spezifisch an die nep-bindungsstelle des qhnpr- pentapeptides binden |
| SI1594517T1 (sl) | 2003-01-28 | 2007-10-31 | Microbia Inc | Sestavki za zdravljenje gastrointestinalnih motenj |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| EP1577320B1 (de) * | 2004-03-19 | 2012-07-18 | Institut Pasteur | Von humanen BPLP Proteinen abgeleitete Peptide, deren kodierende Polynukleotide und Antikörper gegen besagte Peptide |
| DE102004026744A1 (de) * | 2004-05-28 | 2005-12-29 | Philipps-Universität Marburg | Erfindung betreffend cDNA-Herstellung aus Zellen nach Laser-Mikrodissektion |
| US20100120694A1 (en) | 2008-06-04 | 2010-05-13 | Synergy Pharmaceuticals, Inc. | Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| AU2008261102B2 (en) | 2007-06-04 | 2013-11-28 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| ES2714374T3 (es) | 2008-04-07 | 2019-05-28 | Pasteur Institut | Derivados peptídicos de opiorfina como inhibidores potentes de ectopeptidasas degradadoras de encefalina |
| FR2931362B1 (fr) * | 2008-05-26 | 2017-08-18 | Pasteur Institut | L'opiorphine pour une utilisation en tant que psychostimulant. |
| ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
| JP5964589B2 (ja) | 2008-12-03 | 2016-08-03 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼｃアゴニストの製剤およびその使用方法 |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| KR102034748B1 (ko) | 2011-03-01 | 2019-10-21 | 시너지 파마슈티컬즈 인코포레이티드 | 구아닐레이트 사이클라제 c 작용제의 제조 방법 |
| HK1220611A1 (zh) | 2013-03-15 | 2017-05-12 | Bausch Health Ireland Limited | 用於治疗胃肠道病症的组成物 |
| US9708367B2 (en) | 2013-03-15 | 2017-07-18 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
| EP3004138B1 (de) | 2013-06-05 | 2024-03-13 | Bausch Health Ireland Limited | Ultrareine agonisten von guanylatcyclase c, verfahren zur herstellung und verwendung davon |
| CN109212006A (zh) * | 2018-08-24 | 2019-01-15 | 北京艾普希隆生物科技有限公司 | 一种单细胞琼脂糖凝胶电泳试剂盒 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1983003972A1 (en) | 1982-05-06 | 1983-11-24 | Massachusetts Institute Of Technology | Production of enterovirus neutralizing antibodies from vp1 |
| US4699877A (en) | 1982-11-04 | 1987-10-13 | The Regents Of The University Of California | Methods and compositions for detecting human tumors |
| GB8327966D0 (en) | 1983-10-19 | 1983-11-23 | Nyegaard & Co As | Chemical compounds |
| IL78444A (en) * | 1986-04-08 | 1992-05-25 | Yeda Res & Dev | Human gamma interferon-specific receptor protein,antibody against said protein,and compositions containing said protein and antibody |
| FR2637600B1 (fr) * | 1988-10-11 | 1992-03-06 | Pasteur Institut | Peptides et polypeptides provenant de la glande sous maxillaire du rat, anticorps monoclonaux et polyclonaux correspondants, hybridomes correspondants et applications de ces produits au diagnostic, a la detection ou a des fins therapeutiques |
| US5219548A (en) * | 1990-10-01 | 1993-06-15 | Board Of Regents, The University Of Texas System | High affinity halogenated-tamoxifen derivatives and uses thereof |
| EP0705433A4 (de) * | 1993-06-23 | 2001-09-26 | Univ California | Zusammensetzungen und verfahren zum testen auf nicht anhängigmachende narkotische analgetische wirkung und beleuchtungen |
| US6589750B2 (en) * | 1997-02-20 | 2003-07-08 | Institut Pasteur | Therapeutic use of the SMR1 protein, the SMR1 maturation products, specifically the QHNPR pentapeptide as well as its biologically active derivatives |
| DK1185294T3 (da) * | 1999-06-23 | 2005-08-01 | Centre Nat Rech Scient | Peptider til behandling af svækkede interpersonelle og adfærdsmæssige lidelser |
| ATE288763T1 (de) * | 2000-12-22 | 2005-02-15 | Pasteur Institut | Prozess zum screening von molekülen, die spezifisch an die nep-bindungsstelle des qhnpr- pentapeptides binden |
-
1997
- 1997-02-20 US US08/801,405 patent/US6589750B2/en not_active Expired - Lifetime
-
1998
- 1998-02-19 EP EP98912339A patent/EP1007566B1/de not_active Expired - Lifetime
- 1998-02-19 US US09/367,703 patent/US6818405B2/en not_active Expired - Fee Related
- 1998-02-19 AT AT98912339T patent/ATE337339T1/de active
- 1998-02-19 ES ES98912339T patent/ES2271991T3/es not_active Expired - Lifetime
- 1998-02-19 EP EP06009596A patent/EP1702929A3/de not_active Withdrawn
- 1998-02-19 CA CA002281912A patent/CA2281912A1/en not_active Abandoned
- 1998-02-19 PT PT98912339T patent/PT1007566E/pt unknown
- 1998-02-19 DK DK98912339T patent/DK1007566T3/da active
- 1998-02-19 AU AU67219/98A patent/AU6721998A/en not_active Abandoned
- 1998-02-19 DE DE69835680T patent/DE69835680T2/de not_active Expired - Lifetime
- 1998-02-19 WO PCT/EP1998/000956 patent/WO1998037100A2/en not_active Ceased
-
2003
- 2003-05-12 US US10/435,564 patent/US20030195155A1/en not_active Abandoned
- 2003-07-17 US US10/620,462 patent/US7429448B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1702929A3 (de) | 2007-05-23 |
| EP1702929A2 (de) | 2006-09-20 |
| DK1007566T3 (da) | 2007-01-02 |
| US7429448B2 (en) | 2008-09-30 |
| CA2281912A1 (en) | 1998-08-27 |
| US20030195155A1 (en) | 2003-10-16 |
| US6589750B2 (en) | 2003-07-08 |
| EP1007566B1 (de) | 2006-08-23 |
| US20040047805A1 (en) | 2004-03-11 |
| ES2271991T3 (es) | 2007-04-16 |
| US6818405B2 (en) | 2004-11-16 |
| DE69835680T2 (de) | 2007-08-23 |
| PT1007566E (pt) | 2007-01-31 |
| EP1007566A2 (de) | 2000-06-14 |
| US20020198361A1 (en) | 2002-12-26 |
| US20020019008A1 (en) | 2002-02-14 |
| DE69835680D1 (de) | 2006-10-05 |
| WO1998037100A3 (en) | 1999-01-07 |
| WO1998037100A2 (en) | 1998-08-27 |
| AU6721998A (en) | 1998-09-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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