SE464061B - Framstaellning av stabil, frystorkad cis-platina(ii)-diammindiklorid ur en vatten-alkoholloesning - Google Patents

Framstaellning av stabil, frystorkad cis-platina(ii)-diammindiklorid ur en vatten-alkoholloesning

Info

Publication number
SE464061B
SE464061B SE8304920A SE8304920A SE464061B SE 464061 B SE464061 B SE 464061B SE 8304920 A SE8304920 A SE 8304920A SE 8304920 A SE8304920 A SE 8304920A SE 464061 B SE464061 B SE 464061B
Authority
SE
Sweden
Prior art keywords
freeze
solution
water
cisplatin
cis
Prior art date
Application number
SE8304920A
Other languages
English (en)
Swedish (sv)
Other versions
SE8304920L (sv
SE8304920D0 (sv
Inventor
G Battelli
D Oldani
A Rigamonti
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of SE8304920D0 publication Critical patent/SE8304920D0/xx
Publication of SE8304920L publication Critical patent/SE8304920L/xx
Publication of SE464061B publication Critical patent/SE464061B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE8304920A 1982-09-23 1983-09-13 Framstaellning av stabil, frystorkad cis-platina(ii)-diammindiklorid ur en vatten-alkoholloesning SE464061B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23396/82A IT1153974B (it) 1982-09-23 1982-09-23 Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento

Publications (3)

Publication Number Publication Date
SE8304920D0 SE8304920D0 (sv) 1983-09-13
SE8304920L SE8304920L (sv) 1984-03-24
SE464061B true SE464061B (sv) 1991-03-04

Family

ID=11206716

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8304920A SE464061B (sv) 1982-09-23 1983-09-13 Framstaellning av stabil, frystorkad cis-platina(ii)-diammindiklorid ur en vatten-alkoholloesning

Country Status (20)

Country Link
US (1) US4670262A (de)
JP (1) JPS5978117A (de)
AT (1) AT382077B (de)
AU (1) AU559499B2 (de)
BE (1) BE897761A (de)
CA (1) CA1211372A (de)
CH (1) CH655852A5 (de)
DE (1) DE3333024A1 (de)
DK (1) DK157168C (de)
FI (1) FI78236C (de)
FR (1) FR2533439B1 (de)
GB (1) GB2127291B (de)
GR (1) GR79055B (de)
IE (1) IE56173B1 (de)
IL (1) IL69752A (de)
IT (1) IT1153974B (de)
NL (1) NL8303211A (de)
SE (1) SE464061B (de)
SU (1) SU1424722A3 (de)
ZA (1) ZA836904B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8303657A (nl) * 1983-10-24 1985-05-17 Pharmachemie Bv Voor injectie geschikte, stabiele, waterige, zoutzuur bevattende oplossing van cisplatine, alsmede werkwijze ter bereiding daarvan.
IL76889A0 (en) * 1984-11-02 1986-02-28 Johnson Matthey Plc Solubilised platinum compound,method for the production thereof and pharmaceutical compositions containing the same
JPH0665648B2 (ja) * 1985-09-25 1994-08-24 塩野義製薬株式会社 白金系抗癌物質の安定な凍結真空乾燥製剤
JP2524217B2 (ja) * 1988-04-18 1996-08-14 マルハ株式会社 脳機能改善組成物、学習能力増強剤、記憶力増強剤、痴呆予防剤または痴呆治療剤
FI895340A7 (fi) * 1988-11-14 1990-05-15 Bristol Myers Squibb Co Hypertoninen cisplatin-liuos
US20030148933A1 (en) * 1990-10-01 2003-08-07 Pharma Mar S.A. Derivatives of dehydrodidemnin B
WO1994005299A1 (fr) * 1992-09-04 1994-03-17 Fuji Kagaku Kogyo Kabushiki Kaisha Compositions medicinales
FR2759293B1 (fr) * 1997-02-11 1999-04-30 Ethypharm Lab Prod Ethiques Microgranules contenant du cisplatine, procede de fabrication, preparation pharmaceutique et utilisation en polychimiotherapie ou en association avec une radiotherapie
GB9803448D0 (en) 1998-02-18 1998-04-15 Pharma Mar Sa Pharmaceutical formulation
CN1423564A (zh) * 1999-11-15 2003-06-11 法马马有限公司 癌症的aplidine治疗
UA76718C2 (uk) * 2000-06-30 2006-09-15 Фарма Мар, С.А. Протипухлинні похідні аплідину
CZ2003993A3 (cs) * 2000-10-12 2004-02-18 Pharma Mar, S. A. Léčivo pro léčení rakoviny podáváním aplidinu nebo analogu aplidinu a protektoru kosterního svalstva
JP4162491B2 (ja) 2001-01-25 2008-10-08 アメリカ合衆国 ボロン酸化合物製剤
RU2178702C1 (ru) * 2001-02-21 2002-01-27 Общество с ограниченной ответственностью "Нобель" Антираковое средство
WO2003026642A1 (en) * 2001-09-21 2003-04-03 Sumitomo Pharmaceuticals Co., Ltd. Freeze-dried pharmaceutical preparation
WO2003033013A1 (en) * 2001-10-19 2003-04-24 Pharma Mar, S.A. Use of aplidine for the treatment of pancreatic cancer
ATE406171T1 (de) * 2003-03-12 2008-09-15 Dana Farber Cancer Inst Inc Aplidine zur behandlung von multiplem myelom
WO2004080421A2 (en) * 2003-03-12 2004-09-23 Pharma Mar, S.A. Improved antitumoral treatments
DE50305909D1 (de) * 2003-10-13 2007-01-18 Salama Zoser B Pharmazeutische Zusammensetzung umfassend Oxoplatin und dessen Salze
US8436190B2 (en) * 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
CN101389347B (zh) * 2006-02-28 2013-03-27 法马马有限公司 提高的抗肿瘤治疗
AU2008313627A1 (en) * 2007-10-19 2009-04-23 Pharma Mar, S.A. Improved antitumoral treatments
US20110009335A1 (en) * 2008-03-07 2011-01-13 Pharma Mar, S.A. Anticancer Treatments
AR072777A1 (es) 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
EP2326306A1 (de) 2008-09-25 2011-06-01 Cephalon, Inc. Flüssige formulierungen von bendamustin
CN107773538B (zh) * 2016-08-27 2022-09-13 鲁南制药集团股份有限公司 稳定的甲啶铂无菌冻干粉末及其制备工艺
HRP20231233T1 (hr) 2017-04-27 2024-01-19 Pharma Mar, S.A. Antitumorski spojevi

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1432563A (en) * 1972-04-10 1976-04-22 Rustenburg Platinum Mines Ltd Platinum- co-ordination compounds
GB1432562A (en) * 1972-04-10 1976-04-22 Rustenburg Platinum Mines Ltd Platinum co-ordination compounds
US4053587A (en) * 1973-04-13 1977-10-11 Research Corporation Method of treating viral infections
US4255417A (en) * 1976-08-04 1981-03-10 Johnson Matthey, Inc. Platinum compounds for the irradication of skin blemishes
CA1119954A (en) * 1978-05-30 1982-03-16 Edmund S. Granatek Aqueous solution of cisplatin
US4273755A (en) * 1979-08-16 1981-06-16 Mpd Technology Corporation Preparation of platinum complexes
US4302446A (en) * 1979-10-02 1981-11-24 Bristol-Myers Company Pharmaceutical compositions
AU541056B2 (en) * 1980-03-31 1984-12-13 Bristol-Myers Company Pharmaceuticals formulations
US4451447A (en) * 1980-03-31 1984-05-29 Bristol-Myers Company Pharmaceutical formulations

Also Published As

Publication number Publication date
FI78236C (fi) 1989-07-10
IT1153974B (it) 1987-01-21
SE8304920L (sv) 1984-03-24
SU1424722A3 (ru) 1988-09-15
US4670262A (en) 1987-06-02
FI833300A0 (fi) 1983-09-15
BE897761A (fr) 1984-01-02
AU559499B2 (en) 1987-03-12
AU1908983A (en) 1984-03-29
IL69752A (en) 1986-07-31
GB2127291B (en) 1986-01-15
IE56173B1 (en) 1991-05-08
ZA836904B (en) 1984-10-31
DK424383D0 (da) 1983-09-16
GB8324380D0 (en) 1983-10-12
DK424383A (da) 1984-03-24
IL69752A0 (en) 1983-12-30
FI833300A7 (fi) 1984-03-24
JPS5978117A (ja) 1984-05-04
ATA326283A (de) 1986-06-15
FR2533439B1 (fr) 1986-08-14
FR2533439A1 (fr) 1984-03-30
NL8303211A (nl) 1984-04-16
DE3333024A1 (de) 1984-03-29
IE832172L (en) 1984-03-23
DK157168C (da) 1990-04-09
GB2127291A (en) 1984-04-11
AT382077B (de) 1987-01-12
CH655852A5 (de) 1986-05-30
FI78236B (fi) 1989-03-31
IT8223396A0 (it) 1982-09-23
CA1211372A (en) 1986-09-16
SE8304920D0 (sv) 1983-09-13
DK157168B (da) 1989-11-20
GR79055B (de) 1984-10-02

Similar Documents

Publication Publication Date Title
SE464061B (sv) Framstaellning av stabil, frystorkad cis-platina(ii)-diammindiklorid ur en vatten-alkoholloesning
CN101172104B (zh) 抗肿瘤剂,特别是替莫唑胺的药物制剂,其制备方法和用途
JPH05208918A (ja) 静注可能な免疫グロブリン
CN102335123A (zh) 重酒石酸去甲肾上腺素注射液及其制剂工艺
NO125096B (de)
JPH024796A (ja) イホスフアミド‐メスナ凍結乾燥調製物及びその製法
NL8303657A (nl) Voor injectie geschikte, stabiele, waterige, zoutzuur bevattende oplossing van cisplatine, alsmede werkwijze ter bereiding daarvan.
CN105434373A (zh) 一种注射用奥拉西坦冻干制剂及其制备方法
US20160317539A1 (en) Pharmaceutical composition not containing antioxidant and preparation method therefor
HUP0401046A2 (en) Liquid formulation comprising cetuximab and a fatty acid ester of polyoxyethylene sorbitan
Scheiner et al. Thiamine destruction by sodium bisulfite in infusion solutions
Clark et al. Parathyroid glands and calcium and phosphate regulation in the lizard, Anolis carolinensis
WO2009047634A2 (en) Aqueous formulations of acetaminophen for injection
KR860000841B1 (ko) 시스프라틴의 안정화된 농축용액의 제조방법
JPH0924085A (ja) 塩酸ファスジル注射剤
RU2635759C1 (ru) Фармацевтическая композиция для парентерального введения и способ ее получения
RU2242231C2 (ru) Парентеральная композиция для лечения эпилепсии
RU2096043C1 (ru) Антигипоксическое средство и способ его получения
US4915956A (en) Liquid cisplatin formulations
JPH03130226A (ja) １つより多いエチレンイミン基を有する抗新生物性化合物用の安定な製薬学的配合及び方法
US4073907A (en) Stabilized aminophylline solution and process therefor
CN1269487C (zh) 三氧化二砷口服液及其生产方法
RU2504376C1 (ru) Высокостабильный фармацевтический состав на основе лиофилизата производных 3-оксипиридинов, или метилпиридинов, или их фармацевтически приемлемых солей
PT101007B (pt) Preparado liofilizado e estavel de icrf-187 e seu uso e processo de preparacao de liofilizado de icrf-187
Streel et al. Stability of 90 mg/mL Cefuroxime Sodium Solution for Administration by Continuous Infusion

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 8304920-5

Effective date: 19940410

Format of ref document f/p: F