SE8304920L - Farmakologiska kompositioner baserade pa cisplatina och forfarande for framstellning derav - Google Patents

Farmakologiska kompositioner baserade pa cisplatina och forfarande for framstellning derav

Info

Publication number
SE8304920L
SE8304920L SE8304920A SE8304920A SE8304920L SE 8304920 L SE8304920 L SE 8304920L SE 8304920 A SE8304920 A SE 8304920A SE 8304920 A SE8304920 A SE 8304920A SE 8304920 L SE8304920 L SE 8304920L
Authority
SE
Sweden
Prior art keywords
freeze
cisplatinum
drying
dried
solution
Prior art date
Application number
SE8304920A
Other languages
English (en)
Other versions
SE464061B (sv
SE8304920D0 (sv
Inventor
G Battelli
D Oldani
A Rigamonti
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of SE8304920D0 publication Critical patent/SE8304920D0/sv
Publication of SE8304920L publication Critical patent/SE8304920L/sv
Publication of SE464061B publication Critical patent/SE464061B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE8304920A 1982-09-23 1983-09-13 Framstaellning av stabil, frystorkad cis-platina(ii)-diammindiklorid ur en vatten-alkoholloesning SE464061B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23396/82A IT1153974B (it) 1982-09-23 1982-09-23 Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento

Publications (3)

Publication Number Publication Date
SE8304920D0 SE8304920D0 (sv) 1983-09-13
SE8304920L true SE8304920L (sv) 1984-03-24
SE464061B SE464061B (sv) 1991-03-04

Family

ID=11206716

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8304920A SE464061B (sv) 1982-09-23 1983-09-13 Framstaellning av stabil, frystorkad cis-platina(ii)-diammindiklorid ur en vatten-alkoholloesning

Country Status (20)

Country Link
US (1) US4670262A (sv)
JP (1) JPS5978117A (sv)
AT (1) AT382077B (sv)
AU (1) AU559499B2 (sv)
BE (1) BE897761A (sv)
CA (1) CA1211372A (sv)
CH (1) CH655852A5 (sv)
DE (1) DE3333024A1 (sv)
DK (1) DK157168C (sv)
FI (1) FI78236C (sv)
FR (1) FR2533439B1 (sv)
GB (1) GB2127291B (sv)
GR (1) GR79055B (sv)
IE (1) IE56173B1 (sv)
IL (1) IL69752A (sv)
IT (1) IT1153974B (sv)
NL (1) NL8303211A (sv)
SE (1) SE464061B (sv)
SU (1) SU1424722A3 (sv)
ZA (1) ZA836904B (sv)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8303657A (nl) * 1983-10-24 1985-05-17 Pharmachemie Bv Voor injectie geschikte, stabiele, waterige, zoutzuur bevattende oplossing van cisplatine, alsmede werkwijze ter bereiding daarvan.
DK500185A (da) * 1984-11-02 1986-05-03 Johnson Matthey Plc Oploeseliggjort platinforbindelse
JPH0665648B2 (ja) * 1985-09-25 1994-08-24 塩野義製薬株式会社 白金系抗癌物質の安定な凍結真空乾燥製剤
JP2524217B2 (ja) * 1988-04-18 1996-08-14 マルハ株式会社 脳機能改善組成物、学習能力増強剤、記憶力増強剤、痴呆予防剤または痴呆治療剤
FI895340A0 (fi) * 1988-11-14 1989-11-09 Bristol Myers Squibb Co Hypertonisk cisplatin-loesning.
US20030148933A1 (en) * 1990-10-01 2003-08-07 Pharma Mar S.A. Derivatives of dehydrodidemnin B
JPH06192109A (ja) * 1992-09-04 1994-07-12 Fuji Kagaku Kogyo Kk 抗腫瘍効果増強剤
FR2759293B1 (fr) * 1997-02-11 1999-04-30 Ethypharm Lab Prod Ethiques Microgranules contenant du cisplatine, procede de fabrication, preparation pharmaceutique et utilisation en polychimiotherapie ou en association avec une radiotherapie
GB9803448D0 (en) * 1998-02-18 1998-04-15 Pharma Mar Sa Pharmaceutical formulation
AU780417B2 (en) * 1999-11-15 2005-03-17 Pharma Mar S.A. Aplidine treatment of cancers
UA76718C2 (uk) * 2000-06-30 2006-09-15 Фарма Мар, С.А. Протипухлинні похідні аплідину
BR0114604A (pt) * 2000-10-12 2003-10-14 Pharma Mar Sa Tratamento de c‰nceres
EP1360189A1 (en) 2001-01-25 2003-11-12 Millennium Pharmaceuticals, Inc. Formulation of boronic acid compounds
JP4272991B2 (ja) * 2001-09-21 2009-06-03 大日本住友製薬株式会社 凍結乾燥製剤
ES2315404T3 (es) * 2001-10-19 2009-04-01 Pharma Mar, S.A. Uso de aplidina para el tratamiento de cancer de pancreas.
US7576188B2 (en) * 2003-03-12 2009-08-18 Pharma Mar, S.A.U. Antitumoral treatments
DK1603584T3 (da) * 2003-03-12 2009-01-05 Dana Farber Cancer Inst Inc Aplidine til behandling af multipelt myelom
ATE347367T1 (de) * 2003-10-13 2006-12-15 Zoser B Salama Pharmazeutische zusammensetzung umfassend oxoplatin und dessen salze
US8436190B2 (en) 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
RS54928B1 (sr) * 2006-02-28 2016-10-31 Pharma Mar Sa Poboljšano lečenje multiplog mijeloma
JP2011500650A (ja) * 2007-10-19 2011-01-06 ファルマ・マール・ソシエダード・アノニマ 改良された抗腫瘍治療
WO2009111698A1 (en) * 2008-03-07 2009-09-11 Pharma Mar, S.A. Improved anticancer treatments
AR072777A1 (es) 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
CA2735899A1 (en) * 2008-09-25 2010-04-01 Cephalon, Inc. Liquid formulations of bendamustine
CN107773538B (zh) * 2016-08-27 2022-09-13 鲁南制药集团股份有限公司 稳定的甲啶铂无菌冻干粉末及其制备工艺
JOP20190254A1 (ar) 2017-04-27 2019-10-27 Pharma Mar Sa مركبات مضادة للأورام

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1432562A (en) * 1972-04-10 1976-04-22 Rustenburg Platinum Mines Ltd Platinum co-ordination compounds
GB1432563A (en) * 1972-04-10 1976-04-22 Rustenburg Platinum Mines Ltd Platinum- co-ordination compounds
US4053587A (en) * 1973-04-13 1977-10-11 Research Corporation Method of treating viral infections
US4255417A (en) * 1976-08-04 1981-03-10 Johnson Matthey, Inc. Platinum compounds for the irradication of skin blemishes
SE445172B (sv) * 1978-05-30 1986-06-09 Bristol Myers Co Stabil, steril vattenlosning av cisplatin i enhetsdoseringsform
US4273755A (en) * 1979-08-16 1981-06-16 Mpd Technology Corporation Preparation of platinum complexes
US4302446A (en) * 1979-10-02 1981-11-24 Bristol-Myers Company Pharmaceutical compositions
AU541056B2 (en) * 1980-03-31 1984-12-13 Bristol-Myers Company Pharmaceuticals formulations
US4451447A (en) * 1980-03-31 1984-05-29 Bristol-Myers Company Pharmaceutical formulations

Also Published As

Publication number Publication date
IE56173B1 (en) 1991-05-08
DK157168C (da) 1990-04-09
SE464061B (sv) 1991-03-04
AU559499B2 (en) 1987-03-12
SU1424722A3 (ru) 1988-09-15
US4670262A (en) 1987-06-02
CA1211372A (en) 1986-09-16
IL69752A0 (en) 1983-12-30
DK424383D0 (da) 1983-09-16
DK424383A (da) 1984-03-24
IL69752A (en) 1986-07-31
FI78236B (fi) 1989-03-31
JPS5978117A (ja) 1984-05-04
CH655852A5 (de) 1986-05-30
FR2533439A1 (fr) 1984-03-30
GR79055B (sv) 1984-10-02
BE897761A (fr) 1984-01-02
NL8303211A (nl) 1984-04-16
GB2127291B (en) 1986-01-15
ZA836904B (en) 1984-10-31
FI833300A0 (fi) 1983-09-15
IE832172L (en) 1984-03-23
IT8223396A0 (it) 1982-09-23
AT382077B (de) 1987-01-12
FI78236C (sv) 1989-07-10
FI833300A (fi) 1984-03-24
SE8304920D0 (sv) 1983-09-13
DE3333024A1 (de) 1984-03-29
IT1153974B (it) 1987-01-21
AU1908983A (en) 1984-03-29
FR2533439B1 (fr) 1986-08-14
DK157168B (da) 1989-11-20
GB2127291A (en) 1984-04-11
GB8324380D0 (en) 1983-10-12
ATA326283A (de) 1986-06-15

Similar Documents

Publication Publication Date Title
SE8304920L (sv) Farmakologiska kompositioner baserade pa cisplatina och forfarande for framstellning derav
DE3688114D1 (de) Inklusionskomplexe von 7-isopropoxy-isoflavon mit cyclodextrinen, verfahren zu deren herstellung und diese inklusionskomplexe enthaltende pharmazeutische praeparate.
ES2082755T3 (es) Derivados de acido 3-desmetil-mevalonico, procedimiento para su preparacion, preparados farmaceuticos a base de estos compuestos, su utilizacion asi como productos intermedios.
SE8300623D0 (sv) Farmaceutisk komposition innehallande stabil mikrokristallin cis-platina(ii)-diammindiklorid (cisplatin)
NO885213D0 (no) Stabiliserte legemidler, fremgangsmŸte til deres fremstilling samt stabile legemiddeltilberedninger.
HUT38263A (en) Process for rendering active substances soluble and production of therapeutic compositions comprising these substances
ATE101340T1 (de) Neue arzneimittelformulierung sowie verfahren zu deren herstellung.
NO164817C (no) Fremgangsmaate til fremstilling av tofasede, nifedipinholdige, legemiddeltilberedninger.
DK281184D0 (da) Galeniske praeparatformer for orale antidiabetica og fremgangsmaade til deres fremstilling
PT87767A (pt) Process for the manufacture of solid drug preparations containing micronized crystals of 2-phenyl-1,2-benzisoselenazol-3 (2h)-one (ebselen
ES8103972A1 (es) Un procedimiento para preparar una composicion farmaceutica que contiene fumarato de benciclano y ciclodextrina
IL102814A0 (en) Pyrazine derivatives,their preparation and pharmaceutical compositions comprising them
NO870560D0 (no) Fremgangsmaate for fremstilling av et farmasoeytisk preparat
HUP9800120A2 (hu) Hatóanyagként kinolonszármazékokat tartalmazó, semleges ízű gyógyászati készítmények és eljárás előállításukra
NO180473C (no) Fremgangsmåte for fremstilling av et enteralt, farmasöytisk fôrpreparat for behandling av ektoparasittiske fiskesykdommer
HUT51221A (en) Process for producing pharmaceutical compositions comprising 3-demethyl-4-fluoromevalonic acid derivatives and the active ingredients
ATE7698T1 (de) Vincamin-saccharinat und dieses enthaltende arzneimittel.
GB1363047A (en) Pyrimidine derivative process for its preparation and its use as a medicament
NL165740C (nl) Werkwijze ter bereiding van farmaceutische preparaten met anti-inflammatoire werking die as-triazinederivaten bevatten, verkregen gevormde preparaten, alsmede werk- wijze ter bereiding van de actieve as-triazine- derivaten.
ATE285770T1 (de) Verfahren zur herstellung von carbapenem- antibiotika zubereitungen
NO126529B (sv)
DE3378120D1 (en) Thiazaspiro derivatives, process for their preparation and pharmaceutical composition
ATE4808T1 (de) Piperidinderivate von 3-hydroxy-thiophen-2carbons[ureestern,ihre herstellung und diese enthaltende pharmazeutische zubereitungen.
AT342761B (de) Verfahren zur herstellung von homopyrimidazol-derivate enthaltenden, stabilen pharmazeutischen praparaten zur oralen verabreichung
YU83691A (sh) 3'-diamino-4'-deoksi-4'-amino-8-fluoroantraciklini i postupak za njihovu proizvodnju

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 8304920-5

Effective date: 19940410

Format of ref document f/p: F