IT1153974B - Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento - Google Patents

Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento

Info

Publication number
IT1153974B
IT1153974B IT23396/82A IT2339682A IT1153974B IT 1153974 B IT1153974 B IT 1153974B IT 23396/82 A IT23396/82 A IT 23396/82A IT 2339682 A IT2339682 A IT 2339682A IT 1153974 B IT1153974 B IT 1153974B
Authority
IT
Italy
Prior art keywords
obtainment
cisplatin
compositions based
pharmacological compositions
pharmacological
Prior art date
Application number
IT23396/82A
Other languages
English (en)
Other versions
IT8223396A0 (it
Inventor
Gaetano Battelli
Diego Oldani
Alessandro Rigamonti
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of IT8223396A0 publication Critical patent/IT8223396A0/it
Priority to IT23396/82A priority Critical patent/IT1153974B/it
Priority to GB08324380A priority patent/GB2127291B/en
Priority to AU19089/83A priority patent/AU559499B2/en
Priority to AT0326283A priority patent/AT382077B/de
Priority to DE3333024A priority patent/DE3333024A1/de
Priority to SE8304920A priority patent/SE464061B/sv
Priority to JP58168513A priority patent/JPS5978117A/ja
Priority to FI833300A priority patent/FI78236C/fi
Priority to GR72452A priority patent/GR79055B/el
Priority to BE0/211538A priority patent/BE897761A/fr
Priority to CH5037/83A priority patent/CH655852A5/de
Priority to SU833643499A priority patent/SU1424722A3/ru
Priority to IE2172/83A priority patent/IE56173B1/en
Priority to DK424383A priority patent/DK157168C/da
Priority to IL69752A priority patent/IL69752A/xx
Priority to NL8303211A priority patent/NL8303211A/nl
Priority to FR8314772A priority patent/FR2533439B1/fr
Priority to ZA836904A priority patent/ZA836904B/xx
Priority to CA000437117A priority patent/CA1211372A/en
Priority to US06/738,436 priority patent/US4670262A/en
Application granted granted Critical
Publication of IT1153974B publication Critical patent/IT1153974B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT23396/82A 1982-09-23 1982-09-23 Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento IT1153974B (it)

Priority Applications (20)

Application Number Priority Date Filing Date Title
IT23396/82A IT1153974B (it) 1982-09-23 1982-09-23 Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento
GB08324380A GB2127291B (en) 1982-09-23 1983-09-12 Compositions containing cisplatinum
AU19089/83A AU559499B2 (en) 1982-09-23 1983-09-13 Platinum (ii) diaminedichloride compositions
AT0326283A AT382077B (de) 1982-09-23 1983-09-13 Verfahren zur herstellung von pharmazeutischen zusammensetzungen auf basis von cis-platin(ii)-diammindichlorid
DE3333024A DE3333024A1 (de) 1982-09-23 1983-09-13 Neue pharmakologische zusammensetzungen auf basis von cis-platin und verfahren zu deren herstellung
SE8304920A SE464061B (sv) 1982-09-23 1983-09-13 Framstaellning av stabil, frystorkad cis-platina(ii)-diammindiklorid ur en vatten-alkoholloesning
JP58168513A JPS5978117A (ja) 1982-09-23 1983-09-14 新規な薬理学的組成物およびその製造方法
CH5037/83A CH655852A5 (de) 1982-09-23 1983-09-15 Verfahren zur herstellung einer gefriergetrockneten pharmakologischen cis-platin-zusammensetzung.
GR72452A GR79055B (it) 1982-09-23 1983-09-15
BE0/211538A BE897761A (fr) 1982-09-23 1983-09-15 Nouvelles compositions pharmaceutiques a base de cis-platine et procede pour les preparer
FI833300A FI78236C (fi) 1982-09-23 1983-09-15 Foerfarande foer framstaellning av en frystorkad doseringsenhet av cis-platina (ii) diamindiklorid.
SU833643499A SU1424722A3 (ru) 1982-09-23 1983-09-15 Способ получени цисплатины
IL69752A IL69752A (en) 1982-09-23 1983-09-16 Pharmaceutical compositions comprising cisplatinum and their preparation
DK424383A DK157168C (da) 1982-09-23 1983-09-16 Fremgangsmaade til fremstilling af farmaceutiske praeparater paa basis af cis-platin(ii)-diamindichlorid
IE2172/83A IE56173B1 (en) 1982-09-23 1983-09-16 Pharmacological cisplatinum compositions
NL8303211A NL8303211A (nl) 1982-09-23 1983-09-16 Nieuwe farmaceutische preparaten op basis van cisplatinum en werkwijze voor het bereiden daarvan.
FR8314772A FR2533439B1 (fr) 1982-09-23 1983-09-16 Nouvelles compositions pharmaceutiques a base de cis-platine-ii-diammino-dichlorure et procede pour les preparer
ZA836904A ZA836904B (en) 1982-09-23 1983-09-16 Pharmacological compositions
CA000437117A CA1211372A (en) 1982-09-23 1983-09-20 Pharmacological compositions based on cisplatinum and method for obtaining same
US06/738,436 US4670262A (en) 1982-09-23 1985-05-28 Novel pharmacological compositions based on Cisplatinum and method for obtaining same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23396/82A IT1153974B (it) 1982-09-23 1982-09-23 Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento

Publications (2)

Publication Number Publication Date
IT8223396A0 IT8223396A0 (it) 1982-09-23
IT1153974B true IT1153974B (it) 1987-01-21

Family

ID=11206716

Family Applications (1)

Application Number Title Priority Date Filing Date
IT23396/82A IT1153974B (it) 1982-09-23 1982-09-23 Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento

Country Status (20)

Country Link
US (1) US4670262A (it)
JP (1) JPS5978117A (it)
AT (1) AT382077B (it)
AU (1) AU559499B2 (it)
BE (1) BE897761A (it)
CA (1) CA1211372A (it)
CH (1) CH655852A5 (it)
DE (1) DE3333024A1 (it)
DK (1) DK157168C (it)
FI (1) FI78236C (it)
FR (1) FR2533439B1 (it)
GB (1) GB2127291B (it)
GR (1) GR79055B (it)
IE (1) IE56173B1 (it)
IL (1) IL69752A (it)
IT (1) IT1153974B (it)
NL (1) NL8303211A (it)
SE (1) SE464061B (it)
SU (1) SU1424722A3 (it)
ZA (1) ZA836904B (it)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8303657A (nl) * 1983-10-24 1985-05-17 Pharmachemie Bv Voor injectie geschikte, stabiele, waterige, zoutzuur bevattende oplossing van cisplatine, alsmede werkwijze ter bereiding daarvan.
US4696918A (en) * 1984-11-02 1987-09-29 Johnson Matthey Public Limited Company Solubilized platinum compound
JPH0665648B2 (ja) * 1985-09-25 1994-08-24 塩野義製薬株式会社 白金系抗癌物質の安定な凍結真空乾燥製剤
JP2524217B2 (ja) * 1988-04-18 1996-08-14 マルハ株式会社 脳機能改善組成物、学習能力増強剤、記憶力増強剤、痴呆予防剤または痴呆治療剤
FI895340A0 (fi) * 1988-11-14 1989-11-09 Bristol Myers Squibb Co Hypertonisk cisplatin-loesning.
US20030148933A1 (en) * 1990-10-01 2003-08-07 Pharma Mar S.A. Derivatives of dehydrodidemnin B
ATE173627T1 (de) * 1992-09-04 1998-12-15 Fuji Chem Ind Co Ltd Medizinische zusammensetzung
FR2759293B1 (fr) * 1997-02-11 1999-04-30 Ethypharm Lab Prod Ethiques Microgranules contenant du cisplatine, procede de fabrication, preparation pharmaceutique et utilisation en polychimiotherapie ou en association avec une radiotherapie
GB9803448D0 (en) 1998-02-18 1998-04-15 Pharma Mar Sa Pharmaceutical formulation
ES2288486T3 (es) * 1999-11-15 2008-01-16 Pharma Mar, S.A. Tratamiento de canceres con aplidina.
UA76718C2 (uk) * 2000-06-30 2006-09-15 Фарма Мар, С.А. Протипухлинні похідні аплідину
IL155273A0 (en) * 2000-10-12 2003-11-23 Pharma Mar Sa Pharmaceutical compositions comprising an aplidine compound
TR201819416T4 (tr) 2001-01-25 2019-01-21 The United States Of America Represented By The Sec Dep Of Health And Human Services Boronik asit bileşiklerinin formülasyonu.
CN1283242C (zh) * 2001-09-21 2006-11-08 大日本住友制药株式会社 冻干制剂
EP1435991B1 (en) * 2001-10-19 2008-10-15 Pharma Mar, S.A. Use of aplidine for the treatment of pancreatic cancer
AU2004220451B2 (en) * 2003-03-12 2010-01-21 Pharma Mar, S.A. Improved antitumoral treatments
CA2519789C (en) * 2003-03-12 2012-07-03 Dana-Farber Cancer Institute, Inc. Aplidine for multiple myeloma treatment
ATE347367T1 (de) * 2003-10-13 2006-12-15 Zoser B Salama Pharmazeutische zusammensetzung umfassend oxoplatin und dessen salze
US8436190B2 (en) 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
PT2029155E (pt) * 2006-02-28 2016-06-17 Pharma Mar Sa Tratamento melhorado de mieloma múltiplo
AU2008313627A1 (en) * 2007-10-19 2009-04-23 Pharma Mar, S.A. Improved antitumoral treatments
MX2010009697A (es) * 2008-03-07 2010-09-30 Pharm Mar S A Tratamientos anticancerigenos mejorados.
AR072777A1 (es) 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
CA2735899A1 (en) * 2008-09-25 2010-04-01 Cephalon, Inc. Liquid formulations of bendamustine
CN107773538B (zh) * 2016-08-27 2022-09-13 鲁南制药集团股份有限公司 稳定的甲啶铂无菌冻干粉末及其制备工艺
JOP20190254A1 (ar) 2017-04-27 2019-10-27 Pharma Mar Sa مركبات مضادة للأورام

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1432562A (en) * 1972-04-10 1976-04-22 Rustenburg Platinum Mines Ltd Platinum co-ordination compounds
GB1432563A (en) * 1972-04-10 1976-04-22 Rustenburg Platinum Mines Ltd Platinum- co-ordination compounds
US4053587A (en) * 1973-04-13 1977-10-11 Research Corporation Method of treating viral infections
US4255417A (en) * 1976-08-04 1981-03-10 Johnson Matthey, Inc. Platinum compounds for the irradication of skin blemishes
CA1119954A (en) * 1978-05-30 1982-03-16 Edmund S. Granatek Aqueous solution of cisplatin
US4273755A (en) * 1979-08-16 1981-06-16 Mpd Technology Corporation Preparation of platinum complexes
US4302446A (en) * 1979-10-02 1981-11-24 Bristol-Myers Company Pharmaceutical compositions
AU541056B2 (en) * 1980-03-31 1984-12-13 Bristol-Myers Company Pharmaceuticals formulations
US4451447A (en) * 1980-03-31 1984-05-29 Bristol-Myers Company Pharmaceutical formulations

Also Published As

Publication number Publication date
FI78236B (fi) 1989-03-31
FI78236C (fi) 1989-07-10
FR2533439A1 (fr) 1984-03-30
IT8223396A0 (it) 1982-09-23
JPS5978117A (ja) 1984-05-04
IL69752A0 (en) 1983-12-30
GB2127291A (en) 1984-04-11
FI833300A (fi) 1984-03-24
IL69752A (en) 1986-07-31
GB2127291B (en) 1986-01-15
CH655852A5 (de) 1986-05-30
GR79055B (it) 1984-10-02
IE56173B1 (en) 1991-05-08
ATA326283A (de) 1986-06-15
DE3333024A1 (de) 1984-03-29
FR2533439B1 (fr) 1986-08-14
DK157168C (da) 1990-04-09
BE897761A (fr) 1984-01-02
NL8303211A (nl) 1984-04-16
IE832172L (en) 1984-03-23
AT382077B (de) 1987-01-12
CA1211372A (en) 1986-09-16
US4670262A (en) 1987-06-02
SU1424722A3 (ru) 1988-09-15
DK157168B (da) 1989-11-20
SE8304920L (sv) 1984-03-24
AU1908983A (en) 1984-03-29
AU559499B2 (en) 1987-03-12
SE8304920D0 (sv) 1983-09-13
ZA836904B (en) 1984-10-31
GB8324380D0 (en) 1983-10-12
DK424383D0 (da) 1983-09-16
FI833300A0 (fi) 1983-09-15
DK424383A (da) 1984-03-24
SE464061B (sv) 1991-03-04

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