CN105434373A - 一种注射用奥拉西坦冻干制剂及其制备方法 - Google Patents
一种注射用奥拉西坦冻干制剂及其制备方法 Download PDFInfo
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- CN105434373A CN105434373A CN201610015331.1A CN201610015331A CN105434373A CN 105434373 A CN105434373 A CN 105434373A CN 201610015331 A CN201610015331 A CN 201610015331A CN 105434373 A CN105434373 A CN 105434373A
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- injection
- oxiracetam
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- Health & Medical Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (6)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610015331.1A CN105434373B (zh) | 2016-01-11 | 2016-01-11 | 一种注射用奥拉西坦冻干制剂及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201610015331.1A CN105434373B (zh) | 2016-01-11 | 2016-01-11 | 一种注射用奥拉西坦冻干制剂及其制备方法 |
Publications (2)
Publication Number | Publication Date |
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CN105434373A true CN105434373A (zh) | 2016-03-30 |
CN105434373B CN105434373B (zh) | 2018-06-22 |
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CN201610015331.1A Expired - Fee Related CN105434373B (zh) | 2016-01-11 | 2016-01-11 | 一种注射用奥拉西坦冻干制剂及其制备方法 |
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CN (1) | CN105434373B (zh) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106943360A (zh) * | 2016-03-31 | 2017-07-14 | 重庆润泽医药有限公司 | 一种左旋奥拉西坦无菌粉末及其制备方法 |
CN106943361A (zh) * | 2016-03-31 | 2017-07-14 | 重庆润泽医药有限公司 | 一种(s)-4-羟基-2氧代-1-吡咯烷乙酰胺无菌粉末及其制备方法 |
CN106955272A (zh) * | 2016-03-31 | 2017-07-18 | 重庆润泽医药有限公司 | 一种注射用的左旋奥拉西坦无菌粉末及其制备方法 |
CN107468644A (zh) * | 2016-06-08 | 2017-12-15 | 重庆润泽医药有限公司 | 一种左旋奥拉西坦注射剂及其制备方法 |
CN107468640A (zh) * | 2016-06-08 | 2017-12-15 | 重庆润泽医药有限公司 | 左旋奥拉西坦注射剂及其制备方法 |
CN107753481A (zh) * | 2016-08-17 | 2018-03-06 | 沈阳药科大学 | 一种含有缓冲剂的西坦类药物组合物 |
CN113476412A (zh) * | 2021-07-02 | 2021-10-08 | 海南通用康力制药有限公司 | 注射用吡拉西坦冻干粉针剂的制备方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1390543A (zh) * | 2002-07-25 | 2003-01-15 | 湖南省岳阳市制药三厂 | 注射用奥拉西坦药品 |
CN101766597A (zh) * | 2008-12-31 | 2010-07-07 | 北京利乐生制药科技有限公司 | 一种以左旋奥拉西坦为活性成分的注射用制剂 |
CN102274195A (zh) * | 2011-07-18 | 2011-12-14 | 石药集团欧意药业有限公司 | 一种奥拉西坦冻干粉针制剂及其制备方法 |
CN102512378A (zh) * | 2011-12-09 | 2012-06-27 | 天津市汉康医药生物技术有限公司 | 稳定安全的供注射用奥拉西坦药物组合物 |
-
2016
- 2016-01-11 CN CN201610015331.1A patent/CN105434373B/zh not_active Expired - Fee Related
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1390543A (zh) * | 2002-07-25 | 2003-01-15 | 湖南省岳阳市制药三厂 | 注射用奥拉西坦药品 |
CN101766597A (zh) * | 2008-12-31 | 2010-07-07 | 北京利乐生制药科技有限公司 | 一种以左旋奥拉西坦为活性成分的注射用制剂 |
CN102274195A (zh) * | 2011-07-18 | 2011-12-14 | 石药集团欧意药业有限公司 | 一种奥拉西坦冻干粉针制剂及其制备方法 |
CN102512378A (zh) * | 2011-12-09 | 2012-06-27 | 天津市汉康医药生物技术有限公司 | 稳定安全的供注射用奥拉西坦药物组合物 |
Non-Patent Citations (2)
Title |
---|
李代禧等: "奥拉西坦冻干粉针剂的分子调控技术研究", 《计算机与应用化学》 * |
颜素华等: "奥拉西坦注射液的研制", 《中国现代医学杂志》 * |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106943360A (zh) * | 2016-03-31 | 2017-07-14 | 重庆润泽医药有限公司 | 一种左旋奥拉西坦无菌粉末及其制备方法 |
CN106943361A (zh) * | 2016-03-31 | 2017-07-14 | 重庆润泽医药有限公司 | 一种(s)-4-羟基-2氧代-1-吡咯烷乙酰胺无菌粉末及其制备方法 |
CN106955272A (zh) * | 2016-03-31 | 2017-07-18 | 重庆润泽医药有限公司 | 一种注射用的左旋奥拉西坦无菌粉末及其制备方法 |
CN107468644A (zh) * | 2016-06-08 | 2017-12-15 | 重庆润泽医药有限公司 | 一种左旋奥拉西坦注射剂及其制备方法 |
CN107468640A (zh) * | 2016-06-08 | 2017-12-15 | 重庆润泽医药有限公司 | 左旋奥拉西坦注射剂及其制备方法 |
CN107753481A (zh) * | 2016-08-17 | 2018-03-06 | 沈阳药科大学 | 一种含有缓冲剂的西坦类药物组合物 |
CN107753481B (zh) * | 2016-08-17 | 2021-01-15 | 沈阳药科大学 | 一种含有缓冲剂的西坦类药物组合物 |
CN113476412A (zh) * | 2021-07-02 | 2021-10-08 | 海南通用康力制药有限公司 | 注射用吡拉西坦冻干粉针剂的制备方法 |
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Publication number | Publication date |
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CN105434373B (zh) | 2018-06-22 |
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Inventor after: Suo Xiuyan Inventor before: Chen Linghao |
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Effective date of registration: 20180518 Address after: 261400 chronic disease prevention and treatment hospital, No. 1638, Ta Bu Road, Laizhou, Yantai, Shandong Applicant after: Suo Xiuyan Address before: 266520 1 residential 1708, Changjiang East Road, Huangdao District, Qingdao, Shandong, 1708 Applicant before: Chen Da bio tech ltd, Qingdao |
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