SE455835B - Topiskt anbringbar farmaceutisk beredning pa basis av en olje/vattenemulsion samt forfarande for framstellning derav - Google Patents
Topiskt anbringbar farmaceutisk beredning pa basis av en olje/vattenemulsion samt forfarande for framstellning deravInfo
- Publication number
- SE455835B SE455835B SE8305316A SE8305316A SE455835B SE 455835 B SE455835 B SE 455835B SE 8305316 A SE8305316 A SE 8305316A SE 8305316 A SE8305316 A SE 8305316A SE 455835 B SE455835 B SE 455835B
- Authority
- SE
- Sweden
- Prior art keywords
- weight
- gel
- acid
- carbon atoms
- preparation according
- Prior art date
Links
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- VJZWIFWPGRIJSN-NBTZWHCOSA-N octadeca-9,12-dienoic acid;(9z,12z)-octadeca-9,12-dienoic acid Chemical compound CCCCCC=CCC=CCCCCCCCC(O)=O.CCCCC\C=C/C\C=C/CCCCCCCC(O)=O VJZWIFWPGRIJSN-NBTZWHCOSA-N 0.000 description 1
- KHLCTMQBMINUNT-UHFFFAOYSA-N octadecane-1,12-diol Chemical compound CCCCCCC(O)CCCCCCCCCCCO KHLCTMQBMINUNT-UHFFFAOYSA-N 0.000 description 1
- RQFLGKYCYMMRMC-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O.CCCCCCCCCCCCCCCCCC(O)=O RQFLGKYCYMMRMC-UHFFFAOYSA-N 0.000 description 1
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- 229940049964 oleate Drugs 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
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- 238000006864 oxidative decomposition reaction Methods 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
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- WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 description 1
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- 229920000193 polymethacrylate Polymers 0.000 description 1
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 description 1
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 description 1
- 229920006316 polyvinylpyrrolidine Polymers 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- DJEHXEMURTVAOE-UHFFFAOYSA-M potassium bisulfite Chemical compound [K+].OS([O-])=O DJEHXEMURTVAOE-UHFFFAOYSA-M 0.000 description 1
- HEZHYQDYRPUXNJ-UHFFFAOYSA-L potassium dithionite Chemical compound [K+].[K+].[O-]S(=O)S([O-])=O HEZHYQDYRPUXNJ-UHFFFAOYSA-L 0.000 description 1
- 239000004293 potassium hydrogen sulphite Substances 0.000 description 1
- 235000010259 potassium hydrogen sulphite Nutrition 0.000 description 1
- 159000000001 potassium salts Chemical class 0.000 description 1
- BHZRJJOHZFYXTO-UHFFFAOYSA-L potassium sulfite Chemical compound [K+].[K+].[O-]S([O-])=O BHZRJJOHZFYXTO-UHFFFAOYSA-L 0.000 description 1
- 235000019252 potassium sulphite Nutrition 0.000 description 1
- 229960003101 pranoprofen Drugs 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
- 239000000473 propyl gallate Substances 0.000 description 1
- 235000010388 propyl gallate Nutrition 0.000 description 1
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- 150000003217 pyrazoles Chemical class 0.000 description 1
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- 229940045870 sodium palmitate Drugs 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- GGXKEBACDBNFAF-UHFFFAOYSA-M sodium;hexadecanoate Chemical compound [Na+].CCCCCCCCCCCCCCCC([O-])=O GGXKEBACDBNFAF-UHFFFAOYSA-M 0.000 description 1
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- 239000008117 stearic acid Substances 0.000 description 1
- 229930193551 sterin Natural products 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- GKBHKNPLNHLYHT-LWQAOISPSA-N stigmastane Chemical compound C1CC2CCCC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 GKBHKNPLNHLYHT-LWQAOISPSA-N 0.000 description 1
- LAGFCVRVICMFFF-UHFFFAOYSA-N stigmastane Natural products CCC(CCC(C)C1CCC2C3CCC4CC(=O)CC(C)C4C3CCC12C)C(C)C LAGFCVRVICMFFF-UHFFFAOYSA-N 0.000 description 1
- 210000000498 stratum granulosum Anatomy 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 235000011044 succinic acid Nutrition 0.000 description 1
- 150000003444 succinic acids Chemical class 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-L sulfite Chemical compound [O-]S([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-L 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 229960000894 sulindac Drugs 0.000 description 1
- MLKXDPUZXIRXEP-MFOYZWKCSA-N sulindac Chemical compound CC1=C(CC(O)=O)C2=CC(F)=CC=C2\C1=C/C1=CC=C(S(C)=O)C=C1 MLKXDPUZXIRXEP-MFOYZWKCSA-N 0.000 description 1
- 229910021653 sulphate ion Inorganic materials 0.000 description 1
- 229960004492 suprofen Drugs 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- YBRBMKDOPFTVDT-UHFFFAOYSA-N tert-butylamine Chemical compound CC(C)(C)N YBRBMKDOPFTVDT-UHFFFAOYSA-N 0.000 description 1
- ZTUXEFFFLOVXQE-UHFFFAOYSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCCC(O)=O.CCCCCCCCCCCCCC(O)=O ZTUXEFFFLOVXQE-UHFFFAOYSA-N 0.000 description 1
- BRNULMACUQOKMR-UHFFFAOYSA-N thiomorpholine Chemical compound C1CSCCN1 BRNULMACUQOKMR-UHFFFAOYSA-N 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 235000019149 tocopherols Nutrition 0.000 description 1
- 229960002905 tolfenamic acid Drugs 0.000 description 1
- YEZNLOUZAIOMLT-UHFFFAOYSA-N tolfenamic acid Chemical compound CC1=C(Cl)C=CC=C1NC1=CC=CC=C1C(O)=O YEZNLOUZAIOMLT-UHFFFAOYSA-N 0.000 description 1
- 229960001017 tolmetin Drugs 0.000 description 1
- UPSPUYADGBWSHF-UHFFFAOYSA-N tolmetin Chemical compound C1=CC(C)=CC=C1C(=O)C1=CC=C(CC(O)=O)N1C UPSPUYADGBWSHF-UHFFFAOYSA-N 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- FKLSONDBCYHMOQ-ONEGZZNKSA-N trans-dodec-9-enoic acid Chemical compound CC\C=C\CCCCCCCC(O)=O FKLSONDBCYHMOQ-ONEGZZNKSA-N 0.000 description 1
- 229910052723 transition metal Inorganic materials 0.000 description 1
- 150000003624 transition metals Chemical class 0.000 description 1
- 150000005691 triesters Chemical class 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 230000003313 weakening effect Effects 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229960003414 zomepirac Drugs 0.000 description 1
- ZXVNMYWKKDOREA-UHFFFAOYSA-N zomepirac Chemical compound C1=C(CC(O)=O)N(C)C(C(=O)C=2C=CC(Cl)=CC=2)=C1C ZXVNMYWKKDOREA-UHFFFAOYSA-N 0.000 description 1
- QUEDXNHFTDJVIY-UHFFFAOYSA-N γ-tocopherol Chemical class OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH589882A CH655656B (de) | 1982-10-07 | 1982-10-07 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE8305316D0 SE8305316D0 (sv) | 1983-09-29 |
| SE8305316L SE8305316L (sv) | 1984-04-08 |
| SE455835B true SE455835B (sv) | 1988-08-15 |
Family
ID=4301192
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8305316A SE455835B (sv) | 1982-10-07 | 1983-09-29 | Topiskt anbringbar farmaceutisk beredning pa basis av en olje/vattenemulsion samt forfarande for framstellning derav |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US4917886A (de) |
| JP (1) | JPS5989621A (de) |
| KR (1) | KR890000493B1 (de) |
| AT (1) | AT381638B (de) |
| AU (1) | AU567890B2 (de) |
| BE (1) | BE897934A (de) |
| CA (1) | CA1228812A (de) |
| CH (1) | CH655656B (de) |
| DD (1) | DD212897A5 (de) |
| DE (1) | DE3336047C2 (de) |
| DK (1) | DK160913C (de) |
| DO (1) | DOP1990004770A (de) |
| ES (1) | ES526290A0 (de) |
| FI (1) | FI82185C (de) |
| FR (1) | FR2540726B1 (de) |
| GB (1) | GB2128087B (de) |
| GR (1) | GR79660B (de) |
| HK (1) | HK88590A (de) |
| HU (1) | HU190168B (de) |
| IE (1) | IE56023B1 (de) |
| IL (1) | IL69925A (de) |
| IT (1) | IT1174791B (de) |
| LU (1) | LU85030A1 (de) |
| NL (1) | NL193419C (de) |
| NO (1) | NO833645L (de) |
| NZ (1) | NZ205882A (de) |
| PH (1) | PH18646A (de) |
| PT (1) | PT77459B (de) |
| SE (1) | SE455835B (de) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3620674A1 (de) * | 1986-06-20 | 1987-12-23 | Nattermann A & Cie | Salbe zur behandlung von hauterkrankungen |
| CH666621A5 (de) * | 1986-06-27 | 1988-08-15 | Ciba Geigy Ag | Topisch applizierbare pharmazeutische zusammensetzungen mit systemischer wirkung. |
| JP2557657B2 (ja) * | 1987-08-28 | 1996-11-27 | エスエス製薬株式会社 | 経皮吸収促進基剤組成物 |
| WO1989008981A1 (en) * | 1988-03-21 | 1989-10-05 | Daratech Pty Ltd | Teat dip |
| US5160737A (en) * | 1988-05-03 | 1992-11-03 | Perio Products Ltd. | Liquid polymer composition, and method of use |
| US5438076A (en) * | 1988-05-03 | 1995-08-01 | Perio Products, Ltd. | Liquid polymer composition, and method of use |
| US5271945A (en) * | 1988-07-05 | 1993-12-21 | Takeda Chemical Industries, Ltd. | Sustained release microcapsule for water soluble drug |
| US5126141A (en) * | 1988-11-16 | 1992-06-30 | Mediventures Incorporated | Composition and method for post-surgical adhesion reduction with thermo-irreversible gels of polyoxyalkylene polymers and ionic polysaccharides |
| US6436425B1 (en) | 1988-11-16 | 2002-08-20 | Mdv Technologies, Inc. | Method and non-gelling composition for inhibiting post-surgical adhesions |
| US5032384A (en) * | 1989-01-27 | 1991-07-16 | Block Drug Company, Inc. | Compositions and method for the treatment of disease |
| CA2064588A1 (en) * | 1989-08-18 | 1991-02-19 | Akira Nakagawa | Ketotifen preparation for external use |
| JP3273430B2 (ja) * | 1989-12-28 | 2002-04-08 | 日東電工株式会社 | エストロゲン含有ゲル製剤 |
| US5149719A (en) * | 1990-04-27 | 1992-09-22 | Minnesota Mining And Manufacturing Company | Composition for transdermal penetration of medicaments |
| US5346703A (en) | 1990-08-07 | 1994-09-13 | Mediventures, Inc. | Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels |
| US5143731A (en) * | 1990-08-07 | 1992-09-01 | Mediventures Incorporated | Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels |
| US5124151A (en) * | 1990-08-07 | 1992-06-23 | Mediventures Inc. | Drug delivery by injection with thermo-irreversible gels |
| US5077033A (en) * | 1990-08-07 | 1991-12-31 | Mediventures Inc. | Ophthalmic drug delivery with thermo-irreversible gels of polxoxyalkylene polymer and ionic polysaccharide |
| US5071644A (en) * | 1990-08-07 | 1991-12-10 | Mediventures, Inc. | Topical drug delivery with thermo-irreversible gels |
| DE59105323D1 (de) * | 1991-02-07 | 1995-06-01 | Heumann Pharma Gmbh & Co | Neue Salze der 2-(2,6-Dichloranilino)-phenylessigsäure, Verfahren zu ihrer Herstellung und ihre Verwendung für topisch anwendbare pharmazeutische Zubereitungen. |
| CA2112751A1 (en) * | 1991-07-03 | 1993-01-21 | Charles J. Ii Betlach | Composition and method for transdermal delivery of diclofenac |
| US5474985A (en) * | 1993-12-22 | 1995-12-12 | The Regents Of The University Of California | Preventing and treating elevated intraocular pressure associated with administered or endogenous steroids using non-steroidal cyclooxygenase inhibitors |
| AT408067B (de) * | 1995-03-17 | 2001-08-27 | Gebro Pharma Gmbh | Pharmazeutische zusammensetzung zur topischen applizierung und verfahren zu ihrer herstellung |
| US5599535A (en) * | 1995-06-07 | 1997-02-04 | Regents Of The University Of California | Methods for the cyto-protection of the trabecular meshwork |
| US5674888A (en) * | 1995-06-07 | 1997-10-07 | University Of California | Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division |
| DE19641259A1 (de) * | 1996-10-07 | 1998-04-16 | Kade Pharma Fab Gmbh | Arzneimittel auf Basis von Diclofenac |
| DE60045332D1 (de) * | 1999-07-27 | 2011-01-20 | Shiseido Co Ltd | Öl-in-wasser emulsion |
| IL137559A (en) * | 2000-07-27 | 2006-12-31 | Amnon Sintov | A system for administering drugs through the skin |
| TWI290464B (en) | 2000-09-01 | 2007-12-01 | Novartis Consumer Health Sa | Treatment of burns |
| WO2002026239A1 (en) | 2000-09-26 | 2002-04-04 | Temple University Of The Commonwealth System Of Higher Education | Analgesic and glucosamine compositions |
| GB0108082D0 (en) * | 2001-03-30 | 2001-05-23 | Novartis Consumer Health Sa | Topical composition |
| US20030017133A1 (en) * | 2001-06-15 | 2003-01-23 | Wyeth (Formerly American Home Products Corporation) | Mucoadhesive composition |
| US20040028744A1 (en) * | 2002-06-17 | 2004-02-12 | Sauwaluxana Tongaree | Mucoadhesive composition |
| PE20040321A1 (es) * | 2002-08-22 | 2004-07-15 | Novartis Consumer Health Sa | Composicion topica que comprende diclofenaco |
| EP1588697A1 (de) * | 2004-04-16 | 2005-10-26 | Kurt H. Prof. Dr. Bauer | Emulsiongel für die topische Anwendung von Arzneimittel |
| JP2008535954A (ja) * | 2005-03-18 | 2008-09-04 | ビーエーエスエフ ソシエタス・ヨーロピア | 水系およびアルコール系組成物用の増粘剤としてのカチオン性ポリマー |
| JP5042209B2 (ja) | 2005-03-24 | 2012-10-03 | ノーラブズ エービー | 酸化窒素による美容治療、前記治療を実施する装置、及びその製造方法 |
| DE602006012865D1 (de) * | 2005-10-17 | 2010-04-22 | Kowa Co | Indometacin enthaltende flüssige zubereitung zur externen anwendung |
| US8247507B2 (en) | 2006-09-21 | 2012-08-21 | Basf Se | Cationic polymers as thickeners for aqueous and alcoholic compositions |
| EP2055298A1 (de) * | 2007-10-30 | 2009-05-06 | Novartis AG | Topische Zusammensetzung |
| US7943668B2 (en) * | 2008-03-03 | 2011-05-17 | Altergon S.A. | Process for preparing a pharmaceutical composition with anti-inflammatory and analgesic activity for administration via a patch for external use, and composition thus obtained |
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| US9855211B2 (en) | 2013-02-28 | 2018-01-02 | Novan, Inc. | Topical compositions and methods of using the same |
| JP6513667B2 (ja) | 2013-08-08 | 2019-05-15 | ノヴァン，インコーポレイテッド | 局所用組成物およびそれを使用する方法 |
| WO2016022170A1 (en) * | 2014-08-08 | 2016-02-11 | Novan, Inc. | Topical emulsions |
| RU2702898C2 (ru) * | 2014-09-10 | 2019-10-14 | Гск Консьюмер Хелткер С.А. | Композиции диклофенака натрия для местного применения |
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| KR102319497B1 (ko) | 2016-03-02 | 2021-11-01 | 노반, 인크. | 염증 치료용 조성물 및 염증 치료 방법 |
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1982
- 1982-10-07 CH CH589882A patent/CH655656B/de unknown
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1983
- 1983-09-29 SE SE8305316A patent/SE455835B/sv not_active IP Right Cessation
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- 1983-10-04 IL IL69925A patent/IL69925A/xx not_active IP Right Cessation
- 1983-10-04 DE DE3336047A patent/DE3336047C2/de not_active Expired - Lifetime
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- 1983-10-05 FR FR8315858A patent/FR2540726B1/fr not_active Expired
- 1983-10-05 DD DD83255436A patent/DD212897A5/de not_active IP Right Cessation
- 1983-10-05 NL NL8303412A patent/NL193419C/nl not_active IP Right Cessation
- 1983-10-05 CA CA000438372A patent/CA1228812A/en not_active Expired
- 1983-10-05 LU LU85030A patent/LU85030A1/de unknown
- 1983-10-05 IT IT49109/83A patent/IT1174791B/it active
- 1983-10-05 GR GR72628A patent/GR79660B/el unknown
- 1983-10-06 IE IE2356/83A patent/IE56023B1/en not_active IP Right Cessation
- 1983-10-06 AT AT0354683A patent/AT381638B/de not_active IP Right Cessation
- 1983-10-06 HU HU833462A patent/HU190168B/hu unknown
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- 1983-10-06 AU AU19947/83A patent/AU567890B2/en not_active Expired
- 1983-10-06 ES ES526290A patent/ES526290A0/es active Granted
- 1983-10-06 NZ NZ205882A patent/NZ205882A/xx unknown
- 1983-10-06 BE BE0/211657A patent/BE897934A/fr not_active IP Right Cessation
- 1983-10-06 KR KR1019830004739A patent/KR890000493B1/ko not_active IP Right Cessation
- 1983-10-06 DK DK460283A patent/DK160913C/da not_active IP Right Cessation
- 1983-10-06 PT PT77459A patent/PT77459B/pt unknown
- 1983-10-06 NO NO833645A patent/NO833645L/no unknown
- 1983-10-07 JP JP58187160A patent/JPS5989621A/ja active Granted
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1989
- 1989-08-21 US US07/396,781 patent/US4917886A/en not_active Expired - Lifetime
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1990
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- 1990-11-15 DO DO1990004770A patent/DOP1990004770A/es unknown
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