JPS57126414A - Ointment - Google Patents
OintmentInfo
- Publication number
- JPS57126414A JPS57126414A JP1214081A JP1214081A JPS57126414A JP S57126414 A JPS57126414 A JP S57126414A JP 1214081 A JP1214081 A JP 1214081A JP 1214081 A JP1214081 A JP 1214081A JP S57126414 A JPS57126414 A JP S57126414A
- Authority
- JP
- Japan
- Prior art keywords
- component
- crotamiton
- indomethacin
- feeling
- ointment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: A stable gel-like ointment, prepared by incorporating indomethacin with "Crotamiton" as a base, and adjusting the pH to a specific range, having a refreshing feeling and improved feeling of use, and capable of exhibiting the drug effect fully.
CONSTITUTION: A gel-like ointment prepared by incorporating (A) indomethacin which is a nonsteroid anti-inflammatory agent with (B) "Crotamiton" and if necessary a polyethylene glycol ester of a fatty acid, (C) a glycol, (D) a lower alcohol and/or acetone, (E) purified water and (F) a carboxyvinyl polymer, and adjusting the pH to 4.5W6.2. The amount of the respective bases are suitably as follows from the feeling of use, solubility and stability: 2W20wt% component (B), 5W20wt% component (C), 20W50wt% component (D) and 30W60wt% component (E). The "Crotamiton" is partially replaced with polyethylene glycol ester of the fatty acid to improve the solubility of the indomethacin.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1214081A JPS57126414A (en) | 1981-01-28 | 1981-01-28 | Ointment |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1214081A JPS57126414A (en) | 1981-01-28 | 1981-01-28 | Ointment |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57126414A true JPS57126414A (en) | 1982-08-06 |
JPH0135807B2 JPH0135807B2 (en) | 1989-07-27 |
Family
ID=11797198
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1214081A Granted JPS57126414A (en) | 1981-01-28 | 1981-01-28 | Ointment |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57126414A (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59116212A (en) * | 1982-12-23 | 1984-07-05 | Terumo Corp | Indomethacin-containing cream for external application and its preparation |
JPS59190912A (en) * | 1983-04-15 | 1984-10-29 | Hokuriku Seiyaku Co Ltd | Antiinflammatory analgesic cream preparation |
JPS63287721A (en) * | 1987-05-20 | 1988-11-24 | Sato Seiyaku Kk | Anti-inflammatory analgesic gel agent |
US4917886A (en) * | 1982-10-07 | 1990-04-17 | Ciba-Geigy Corporation | Novel topically administrable pharmaceutical compositions |
JPH0372433A (en) * | 1989-04-28 | 1991-03-27 | Hisamitsu Pharmaceut Co Inc | Foamy aerosol preparation |
JPH04217925A (en) * | 1990-03-27 | 1992-08-07 | Nippon Saafuakutanto Kogyo Kk | New antipyretic, antiphlogistic and analgesic agent composition |
WO2004010994A1 (en) | 2002-07-29 | 2004-02-05 | Kowa Company, Ltd. | Indometacin preparation for external use |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5798209A (en) * | 1980-12-09 | 1982-06-18 | Kowa Co | Remedy for dermatopathy for external use |
-
1981
- 1981-01-28 JP JP1214081A patent/JPS57126414A/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5798209A (en) * | 1980-12-09 | 1982-06-18 | Kowa Co | Remedy for dermatopathy for external use |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4917886A (en) * | 1982-10-07 | 1990-04-17 | Ciba-Geigy Corporation | Novel topically administrable pharmaceutical compositions |
JPS59116212A (en) * | 1982-12-23 | 1984-07-05 | Terumo Corp | Indomethacin-containing cream for external application and its preparation |
JPH0380774B2 (en) * | 1982-12-23 | 1991-12-26 | Terumo Corp | |
JPS59190912A (en) * | 1983-04-15 | 1984-10-29 | Hokuriku Seiyaku Co Ltd | Antiinflammatory analgesic cream preparation |
JPS63287721A (en) * | 1987-05-20 | 1988-11-24 | Sato Seiyaku Kk | Anti-inflammatory analgesic gel agent |
JPH0372433A (en) * | 1989-04-28 | 1991-03-27 | Hisamitsu Pharmaceut Co Inc | Foamy aerosol preparation |
JPH07112984B2 (en) * | 1989-04-28 | 1995-12-06 | 久光製薬株式会社 | Foam aerosol formulation |
JPH04217925A (en) * | 1990-03-27 | 1992-08-07 | Nippon Saafuakutanto Kogyo Kk | New antipyretic, antiphlogistic and analgesic agent composition |
WO2004010994A1 (en) | 2002-07-29 | 2004-02-05 | Kowa Company, Ltd. | Indometacin preparation for external use |
US7553865B2 (en) | 2002-07-29 | 2009-06-30 | Kowa Company, Ltd. | Indomethacin external preparation |
Also Published As
Publication number | Publication date |
---|---|
JPH0135807B2 (en) | 1989-07-27 |
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