JPS57126414A - Ointment - Google Patents

Ointment

Info

Publication number
JPS57126414A
JPS57126414A JP1214081A JP1214081A JPS57126414A JP S57126414 A JPS57126414 A JP S57126414A JP 1214081 A JP1214081 A JP 1214081A JP 1214081 A JP1214081 A JP 1214081A JP S57126414 A JPS57126414 A JP S57126414A
Authority
JP
Japan
Prior art keywords
component
crotamiton
indomethacin
feeling
ointment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1214081A
Other languages
Japanese (ja)
Other versions
JPH0135807B2 (en
Inventor
Yoshinari Yamahira
Tetsuo Noguchi
Masako Hirose
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Priority to JP1214081A priority Critical patent/JPS57126414A/en
Publication of JPS57126414A publication Critical patent/JPS57126414A/en
Publication of JPH0135807B2 publication Critical patent/JPH0135807B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: A stable gel-like ointment, prepared by incorporating indomethacin with "Crotamiton" as a base, and adjusting the pH to a specific range, having a refreshing feeling and improved feeling of use, and capable of exhibiting the drug effect fully.
CONSTITUTION: A gel-like ointment prepared by incorporating (A) indomethacin which is a nonsteroid anti-inflammatory agent with (B) "Crotamiton" and if necessary a polyethylene glycol ester of a fatty acid, (C) a glycol, (D) a lower alcohol and/or acetone, (E) purified water and (F) a carboxyvinyl polymer, and adjusting the pH to 4.5W6.2. The amount of the respective bases are suitably as follows from the feeling of use, solubility and stability: 2W20wt% component (B), 5W20wt% component (C), 20W50wt% component (D) and 30W60wt% component (E). The "Crotamiton" is partially replaced with polyethylene glycol ester of the fatty acid to improve the solubility of the indomethacin.
COPYRIGHT: (C)1982,JPO&Japio
JP1214081A 1981-01-28 1981-01-28 Ointment Granted JPS57126414A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1214081A JPS57126414A (en) 1981-01-28 1981-01-28 Ointment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1214081A JPS57126414A (en) 1981-01-28 1981-01-28 Ointment

Publications (2)

Publication Number Publication Date
JPS57126414A true JPS57126414A (en) 1982-08-06
JPH0135807B2 JPH0135807B2 (en) 1989-07-27

Family

ID=11797198

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1214081A Granted JPS57126414A (en) 1981-01-28 1981-01-28 Ointment

Country Status (1)

Country Link
JP (1) JPS57126414A (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59116212A (en) * 1982-12-23 1984-07-05 Terumo Corp Indomethacin-containing cream for external application and its preparation
JPS59190912A (en) * 1983-04-15 1984-10-29 Hokuriku Seiyaku Co Ltd Antiinflammatory analgesic cream preparation
JPS63287721A (en) * 1987-05-20 1988-11-24 Sato Seiyaku Kk Anti-inflammatory analgesic gel agent
US4917886A (en) * 1982-10-07 1990-04-17 Ciba-Geigy Corporation Novel topically administrable pharmaceutical compositions
JPH0372433A (en) * 1989-04-28 1991-03-27 Hisamitsu Pharmaceut Co Inc Foamy aerosol preparation
JPH04217925A (en) * 1990-03-27 1992-08-07 Nippon Saafuakutanto Kogyo Kk New antipyretic, antiphlogistic and analgesic agent composition
WO2004010994A1 (en) 2002-07-29 2004-02-05 Kowa Company, Ltd. Indometacin preparation for external use

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5798209A (en) * 1980-12-09 1982-06-18 Kowa Co Remedy for dermatopathy for external use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5798209A (en) * 1980-12-09 1982-06-18 Kowa Co Remedy for dermatopathy for external use

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4917886A (en) * 1982-10-07 1990-04-17 Ciba-Geigy Corporation Novel topically administrable pharmaceutical compositions
JPS59116212A (en) * 1982-12-23 1984-07-05 Terumo Corp Indomethacin-containing cream for external application and its preparation
JPH0380774B2 (en) * 1982-12-23 1991-12-26 Terumo Corp
JPS59190912A (en) * 1983-04-15 1984-10-29 Hokuriku Seiyaku Co Ltd Antiinflammatory analgesic cream preparation
JPS63287721A (en) * 1987-05-20 1988-11-24 Sato Seiyaku Kk Anti-inflammatory analgesic gel agent
JPH0372433A (en) * 1989-04-28 1991-03-27 Hisamitsu Pharmaceut Co Inc Foamy aerosol preparation
JPH07112984B2 (en) * 1989-04-28 1995-12-06 久光製薬株式会社 Foam aerosol formulation
JPH04217925A (en) * 1990-03-27 1992-08-07 Nippon Saafuakutanto Kogyo Kk New antipyretic, antiphlogistic and analgesic agent composition
WO2004010994A1 (en) 2002-07-29 2004-02-05 Kowa Company, Ltd. Indometacin preparation for external use
US7553865B2 (en) 2002-07-29 2009-06-30 Kowa Company, Ltd. Indomethacin external preparation

Also Published As

Publication number Publication date
JPH0135807B2 (en) 1989-07-27

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