SE453796B - Fast, terapeutisk komposition vars berarbasmaterial utgores av hydroxypropylmetylcellulosa samt ev natriumkarboximetylcellulosa - Google Patents
Fast, terapeutisk komposition vars berarbasmaterial utgores av hydroxypropylmetylcellulosa samt ev natriumkarboximetylcellulosaInfo
- Publication number
- SE453796B SE453796B SE8207167A SE8207167A SE453796B SE 453796 B SE453796 B SE 453796B SE 8207167 A SE8207167 A SE 8207167A SE 8207167 A SE8207167 A SE 8207167A SE 453796 B SE453796 B SE 453796B
- Authority
- SE
- Sweden
- Prior art keywords
- weight
- tablets
- drugs
- tablet
- minutes
- Prior art date
Links
- -1 HYDROXYPROPYLMETHYL Chemical class 0.000 title claims description 34
- 239000000203 mixture Substances 0.000 title claims description 21
- 239000000463 material Substances 0.000 title claims description 7
- 230000001225 therapeutic effect Effects 0.000 title description 4
- 239000011734 sodium Substances 0.000 title description 2
- 229910052708 sodium Inorganic materials 0.000 title description 2
- 229940079593 drug Drugs 0.000 claims description 56
- 239000003814 drug Substances 0.000 claims description 56
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims description 35
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 35
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims description 31
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims description 31
- 239000004615 ingredient Substances 0.000 claims description 22
- 239000004480 active ingredient Substances 0.000 claims description 7
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 6
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 6
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 6
- 230000000694 effects Effects 0.000 claims description 5
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 5
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- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 6
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- SNIOPGDIGTZGOP-UHFFFAOYSA-N Nitroglycerin Chemical compound [O-][N+](=O)OCC(O[N+]([O-])=O)CO[N+]([O-])=O SNIOPGDIGTZGOP-UHFFFAOYSA-N 0.000 description 3
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- RPTUSVTUFVMDQK-UHFFFAOYSA-N Hidralazin Chemical compound C1=CC=C2C(NN)=NN=CC2=C1 RPTUSVTUFVMDQK-UHFFFAOYSA-N 0.000 description 2
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- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 2
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- BRUQQQPBMZOVGD-XFKAJCMBSA-N Oxycodone Chemical compound O=C([C@@H]1O2)CC[C@@]3(O)[C@H]4CC5=CC=C(OC)C2=C5[C@@]13CCN4C BRUQQQPBMZOVGD-XFKAJCMBSA-N 0.000 description 2
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- FJPYVLNWWICYDW-UHFFFAOYSA-M sodium;5,5-diphenylimidazolidin-1-ide-2,4-dione Chemical compound [Na+].O=C1[N-]C(=O)NC1(C=1C=CC=CC=1)C1=CC=CC=C1 FJPYVLNWWICYDW-UHFFFAOYSA-M 0.000 description 1
- LXMSZDCAJNLERA-ZHYRCANASA-N spironolactone Chemical compound C([C@@H]1[C@]2(C)CC[C@@H]3[C@@]4(C)CCC(=O)C=C4C[C@H]([C@@H]13)SC(=O)C)C[C@@]21CCC(=O)O1 LXMSZDCAJNLERA-ZHYRCANASA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/332,348 US4369172A (en) | 1981-12-18 | 1981-12-18 | Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE8207167D0 SE8207167D0 (sv) | 1982-12-15 |
| SE8207167L SE8207167L (sv) | 1983-06-19 |
| SE453796B true SE453796B (sv) | 1988-03-07 |
Family
ID=23297834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8207167A SE453796B (sv) | 1981-12-18 | 1982-12-15 | Fast, terapeutisk komposition vars berarbasmaterial utgores av hydroxypropylmetylcellulosa samt ev natriumkarboximetylcellulosa |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4369172A (cs) |
| JP (1) | JPS58110513A (cs) |
| AR (1) | AR228699A1 (cs) |
| BE (1) | BE895391A (cs) |
| CA (1) | CA1195929A (cs) |
| CH (1) | CH641670A5 (cs) |
| DE (1) | DE3246492C2 (cs) |
| DK (1) | DK160076C (cs) |
| ES (1) | ES518321A0 (cs) |
| FR (1) | FR2518409B1 (cs) |
| GB (1) | GB2111386A (cs) |
| IL (1) | IL67497A (cs) |
| IT (1) | IT1164472B (cs) |
| MX (1) | MX160316A (cs) |
| NL (1) | NL190472C (cs) |
| SE (1) | SE453796B (cs) |
| ZA (1) | ZA829267B (cs) |
Families Citing this family (344)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3360633D1 (en) * | 1982-02-12 | 1985-10-03 | Unitika Ltd | Anti-cancer device |
| US4389393A (en) * | 1982-03-26 | 1983-06-21 | Forest Laboratories, Inc. | Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose |
| DE3435325A1 (de) * | 1983-04-09 | 1986-04-17 | Nikken Chemicals Co., Ltd., Tokio/Tokyo | Langzeitwirkende theophyllin-tablette und verfahren zu deren herstellung |
| US4591500A (en) * | 1983-04-25 | 1986-05-27 | Microencapsulation S.A. | Tablet having the shape of a capsule, process and device for its preparation |
| JPH0662404B2 (ja) * | 1983-06-14 | 1994-08-17 | シンテックス・ファーマシユーテイカルズ・インターナシヨナル・リミテツド | 制御放出性ナプロキセンおよびナプロキセンナトリウム錠 |
| US4571333A (en) * | 1983-06-14 | 1986-02-18 | Syntex (U.S.A.) Inc. | Controlled release naproxen and naproxen sodium tablets |
| IL72381A (en) * | 1983-07-20 | 1988-03-31 | Sanofi Sa | Pharmaceutical composition based on valproic acid |
| JPS6038322A (ja) * | 1983-08-11 | 1985-02-27 | Fujisawa Pharmaceut Co Ltd | ジヒドロピリジンａ物質含有易溶性固形製剤 |
| US4680323A (en) * | 1983-12-01 | 1987-07-14 | Hans Lowey | Method and composition for the preparation of controlled long-acting pharmaceuticals for oral administration |
| FR2556965B1 (fr) * | 1983-12-21 | 1986-08-22 | Rhone Poulenc Sante | Nouvelle forme galenique du ketoprofene a liberation controlee |
| GB8403360D0 (en) * | 1984-02-08 | 1984-03-14 | Erba Farmitalia | Pharmaceutical compositions |
| CH666406A5 (de) * | 1984-02-29 | 1988-07-29 | Sandoz Ag | Verfahren zur herstellung von mikrokapseln, welche bromokriptinmesylat als pharmakologischen wirkstoff enthalten. |
| GB2154874B (en) * | 1984-02-29 | 1987-11-04 | Sandoz Ltd | Bromoscriptine compositions |
| US4795327A (en) * | 1984-03-26 | 1989-01-03 | Forest Laboratories, Inc. | Controlled release solid drug dosage forms based on mixtures of water soluble nonionic cellulose ethers and anionic surfactants |
| US4540566A (en) * | 1984-04-02 | 1985-09-10 | Forest Laboratories, Inc. | Prolonged release drug dosage forms based on modified low viscosity grade hydroxypropylmethylcellulose |
| GB8414220D0 (en) * | 1984-06-04 | 1984-07-11 | Sterwin Ag | Medicaments in unit dose form |
| US4532244A (en) * | 1984-09-06 | 1985-07-30 | Innes Margaret N | Method of treating migraine headaches |
| US4678516A (en) * | 1984-10-09 | 1987-07-07 | The Dow Chemical Company | Sustained release dosage form based on highly plasticized cellulose ether gels |
| AU592065B2 (en) * | 1984-10-09 | 1990-01-04 | Dow Chemical Company, The | Sustained release dosage form based on highly plasticized cellulose ether gels |
| US4695464A (en) * | 1984-10-09 | 1987-09-22 | The Dow Chemical Company | Sustained release dosage form based on highly plasticized cellulose ether gels |
| US4639458A (en) * | 1985-01-22 | 1987-01-27 | Merck & Co., Inc. | Tablet and formulation |
| AT388101B (de) * | 1985-02-05 | 1989-05-10 | Sandoz Ag | Verfahren zur herstellung einer pharmazeutischen zusammensetzung zur oralen verabreichung mit kontrollierter wirkstofffreisetzung |
| NL8600161A (nl) * | 1985-02-05 | 1986-09-01 | Sandoz Ag | Farmaceutische preparaten die 9,10-dihydroergotalkaloiden bevatten. |
| AU598751B2 (en) * | 1985-02-07 | 1990-07-05 | Novartis Ag | Pharmaceutical formulations with controlled release of the active substance |
| US4657757A (en) * | 1985-03-29 | 1987-04-14 | Schering Corporation | Controlled release dosage form comprising acetaminophen, pseudoephedrine sulfate and dexbrompheniramine maleate |
| US4695591A (en) * | 1985-03-29 | 1987-09-22 | Schering Corporation | Controlled release dosage forms comprising hydroxypropylmethylcellulose |
| US4601894A (en) * | 1985-03-29 | 1986-07-22 | Schering Corporation | Controlled release dosage form comprising acetaminophen, pseudoephedrine sulfate and dexbrompheniramine maleate |
| US4885173A (en) * | 1985-05-01 | 1989-12-05 | University Of Utah | Methods and compositions for noninvasive dose-to-effect administration of drugs with cardiovascular or renal vascular activities |
| WO1987000044A1 (en) * | 1985-07-02 | 1987-01-15 | The Upjohn Company | Therapeutic formulations with bimodal release characteristics |
| GB8518301D0 (en) * | 1985-07-19 | 1985-08-29 | Fujisawa Pharmaceutical Co | Hydrodynamically explosive systems |
| NL194822C (nl) * | 1985-10-01 | 2003-04-03 | Novartis Ag | Preparaat voor orale toediening met geregelde afgifte en werkwijze voor de bereiding ervan. |
| GB2181053B (en) * | 1985-10-01 | 1990-05-23 | Sandoz Ltd | Pharmaceutical formulations with controlled release of the active substance |
| IT1187750B (it) * | 1985-10-15 | 1987-12-23 | Eurand Spa | Procedimento per la preparazione di compresse,anche a rilascio prolungato,di iscsorbide-5-mononitrato stabilizzato e formulazioni cosi' ottenute |
| US4734285A (en) * | 1985-10-28 | 1988-03-29 | The Dow Chemical Company | Sustained release compositions |
| US4704285A (en) * | 1985-11-18 | 1987-11-03 | The Dow Chemical Company | Sustained release compositions comprising hydroxypropyl cellulose ethers |
| IE63321B1 (en) * | 1986-02-03 | 1995-04-05 | Elan Corp Plc | Drug delivery system |
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| DK160076B (da) | 1991-01-28 |
| DE3246492A1 (de) | 1983-06-30 |
| ES8402155A1 (es) | 1984-01-16 |
| IT1164472B (it) | 1987-04-08 |
| IL67497A0 (en) | 1983-05-15 |
| JPS58110513A (ja) | 1983-07-01 |
| MX160316A (es) | 1990-02-01 |
| BE895391A (fr) | 1983-04-15 |
| ZA829267B (en) | 1983-08-31 |
| ES518321A0 (es) | 1984-01-16 |
| IL67497A (en) | 1986-02-28 |
| NL190472B (nl) | 1993-10-18 |
| AR228699A1 (es) | 1983-03-30 |
| US4369172A (en) | 1983-01-18 |
| GB2111386A (en) | 1983-07-06 |
| DK560782A (da) | 1983-06-19 |
| FR2518409B1 (fr) | 1986-02-21 |
| CH641670A5 (fr) | 1984-03-15 |
| CA1195929A (en) | 1985-10-29 |
| DE3246492C2 (de) | 1985-12-19 |
| FR2518409A1 (fr) | 1983-06-24 |
| SE8207167D0 (sv) | 1982-12-15 |
| IT8212690A0 (it) | 1982-12-16 |
| SE8207167L (sv) | 1983-06-19 |
| GB2111386B (cs) | |
| DK160076C (da) | 1991-06-24 |
| NL8204893A (nl) | 1983-07-18 |
| NL190472C (nl) | 1994-03-16 |
| JPH059413B2 (cs) | 1993-02-04 |
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