ZA989356B - Pharmaceutical preparations - Google Patents

Pharmaceutical preparations

Info

Publication number
ZA989356B
ZA989356B ZA989356A ZA989356A ZA989356B ZA 989356 B ZA989356 B ZA 989356B ZA 989356 A ZA989356 A ZA 989356A ZA 989356 A ZA989356 A ZA 989356A ZA 989356 B ZA989356 B ZA 989356B
Authority
ZA
South Africa
Prior art keywords
pentaerythritol
pharmaceutical preparations
dinatrate
pentaerythrito
petn
Prior art date
Application number
ZA989356A
Inventor
Ulrich Guenther Ulrike Kuntze
Wilhelm Thomas Lehr Freita Nat
Original Assignee
Isis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isis Pharma Gmbh filed Critical Isis Pharma Gmbh
Publication of ZA989356B publication Critical patent/ZA989356B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention relates to new, in particular orally administered pharmaceutical preparations containing, as pharmaceutical agent, pentaerythritol tetranitrate (PETN) or its metabolites pentaerythritol trinitrate, pentaerythritol dinatrate and pentaerythrito mononitrate, in amounts which guarantee the patient a sufficient dosage with one administering (per day).
ZA989356A 1997-10-16 1998-10-14 Pharmaceutical preparations ZA989356B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19745618 1997-10-16

Publications (1)

Publication Number Publication Date
ZA989356B true ZA989356B (en) 1998-11-16

Family

ID=7845649

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA989356A ZA989356B (en) 1997-10-16 1998-10-14 Pharmaceutical preparations

Country Status (12)

Country Link
EP (1) EP1023059B1 (en)
AT (1) ATE313323T1 (en)
AU (1) AU1660399A (en)
CZ (1) CZ301265B6 (en)
DE (3) DE29880094U1 (en)
DK (1) DK1023059T3 (en)
ES (1) ES2255193T3 (en)
HU (1) HUP0100634A3 (en)
PL (1) PL340386A1 (en)
SK (1) SK284769B6 (en)
WO (1) WO1999018930A2 (en)
ZA (1) ZA989356B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1087926A2 (en) * 1998-06-24 2001-04-04 Alpharma-Isis GmbH & Co. KG Analytic substrates and antioxidative agents
DE102008050597A1 (en) 2008-10-09 2010-04-15 Actavis Deutschland Gmbh & Co. Kg Preparation, useful for treating and preventing idiopathic sudden sensorineural hearing loss, comprises pentaerythritol tetra-, pentaerythritol trinitrate, pentaerythritol dinitrate or pentaerythritol mononitrate, and an excipient

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3028307A (en) * 1959-05-27 1962-04-03 Warner Lambert Pharmaceutical Pre-dried granulation and production of sublingual compressed organic nitrate tablets with selected solubilizing agents
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
ATE49503T1 (en) * 1982-09-29 1990-02-15 Ici America Inc MEDICINAL COMPOSITIONS CONTAINING ORGANIC NITRATES STABLE TO DETONATION BY FIRE.
DE3328094A1 (en) * 1983-08-04 1985-02-21 H. Trommsdorff GmbH & Co, 5110 Alsdorf Desensitised pharmaceutical formulation of explosive nitric acid esters
DE68906539D1 (en) * 1989-02-20 1993-06-17 Soorianarain Baligadoo PHARMACEUTICAL HEART-PROTECTING COMPOSITIONS CONTAINING AMIODARON, A NITRO DERIVATIVE, IN PARTICULAR ISOSORBIDE DINITRATE, AND, IF NECESSARY, A BETABLOCKER.
US5278192A (en) * 1992-07-02 1994-01-11 The Research Foundation Of State University Of New York Method of vasodilator therapy for treating a patient with a condition
DE4410997A1 (en) * 1994-03-30 1995-10-26 Isis Pharma Gmbh Pharmaceutical preparations and drugs for the prevention and treatment of endothelial dysfunctions

Also Published As

Publication number Publication date
EP1023059B1 (en) 2005-12-21
HUP0100634A3 (en) 2003-07-28
CZ20001342A3 (en) 2000-09-13
AU1660399A (en) 1999-05-03
EP1023059A2 (en) 2000-08-02
WO1999018930A2 (en) 1999-04-22
ES2255193T3 (en) 2006-06-16
WO1999018930A3 (en) 1999-10-07
DE59813300D1 (en) 2006-01-26
ATE313323T1 (en) 2006-01-15
PL340386A1 (en) 2001-01-29
DK1023059T3 (en) 2006-04-24
HUP0100634A2 (en) 2001-07-30
CZ301265B6 (en) 2009-12-23
SK284769B6 (en) 2005-11-03
DE29880094U1 (en) 2000-05-18
DE19847781A1 (en) 1999-04-22
SK5382000A3 (en) 2000-11-07

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