GB1171691A - Lond-Acting Oral Carrier - Google Patents

Lond-Acting Oral Carrier

Info

Publication number
GB1171691A
GB1171691A GB900467A GB900467A GB1171691A GB 1171691 A GB1171691 A GB 1171691A GB 900467 A GB900467 A GB 900467A GB 900467 A GB900467 A GB 900467A GB 1171691 A GB1171691 A GB 1171691A
Authority
GB
United Kingdom
Prior art keywords
lond
product
oral carrier
compressed
carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB900467A
Inventor
Hans Lowey
Herbert Henry Stafford
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Forest Laboratories LLC
Original Assignee
Forest Laboratories LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forest Laboratories LLC filed Critical Forest Laboratories LLC
Priority to GB900467A priority Critical patent/GB1171691A/en
Priority claimed from FR1589378D external-priority patent/FR1589378A/fr
Publication of GB1171691A publication Critical patent/GB1171691A/en
Application status is Expired legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays

Abstract

1,171,691. Sustained release compositions. FOREST LABORATORIES, Inc. 24 Feb., 1967, No. 9004/67, Heading A5B. A pharmaceutical form for sustained buccal or sublingual administration consists of a shaped compressed product comprising a carrier of 100-80% methyl cellulose and 0-20% ethyl cellulose together with a therapeutically active ingredient, compressed at a pressure of 5-8 Ibs./sq. inch. The rate and duration of release of the active agent, which is either locally absorbed or swallowed in the saliva, is controlled by the size and shape of the product, and by the relative proportions of the two cellulose derivatives.
GB900467A 1967-02-24 1967-02-24 Lond-Acting Oral Carrier Expired GB1171691A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB900467A GB1171691A (en) 1967-02-24 1967-02-24 Lond-Acting Oral Carrier

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB900467A GB1171691A (en) 1967-02-24 1967-02-24 Lond-Acting Oral Carrier
NL6802594A NL142073B (en) 1967-02-24 1968-02-23 A process for the preparation of a, a hydroxyalkyl cellulose containing as a carrier, formed of drug and thus-obtained molded product.
DK73968A DK122997B (en) 1967-02-24 1968-02-23 A process for the manufacture of tablets.
FR1589378D FR1589378A (en) 1967-02-24 1968-02-23
BE711241D BE711241A (en) 1967-02-24 1968-02-23
DE1968L0058659 DE1667888C3 (en) 1967-02-24 1968-03-23

Publications (1)

Publication Number Publication Date
GB1171691A true GB1171691A (en) 1969-11-26

Family

ID=9863505

Family Applications (1)

Application Number Title Priority Date Filing Date
GB900467A Expired GB1171691A (en) 1967-02-24 1967-02-24 Lond-Acting Oral Carrier

Country Status (5)

Country Link
BE (1) BE711241A (en)
DE (1) DE1667888C3 (en)
DK (1) DK122997B (en)
GB (1) GB1171691A (en)
NL (1) NL142073B (en)

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2190409A1 (en) * 1972-06-26 1974-02-01 Lowey Hans
FR2361914A1 (en) * 1975-07-09 1978-03-17 Bayer Ag New formulations of medicines at reduced risk of misuse
US4163777A (en) * 1977-04-29 1979-08-07 Lewis/Howe Company Controlled antacid delivery form and method of treatment therewith
DE3246492A1 (en) * 1981-12-18 1983-06-30 Forest Laboratories A process for the production of therapeutic preparations on the basis of hydroxypropyl methyl cellulose with an extended release pattern
US4680323A (en) * 1983-12-01 1987-07-14 Hans Lowey Method and composition for the preparation of controlled long-acting pharmaceuticals for oral administration
US4764378A (en) * 1986-02-10 1988-08-16 Zetachron, Inc. Buccal drug dosage form
US4775535A (en) * 1986-04-04 1988-10-04 Hans Lowey Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics
US4855143A (en) * 1986-04-04 1989-08-08 Hans Lowey Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics
US4863737A (en) * 1985-05-01 1989-09-05 University Of Utah Compositions and methods of manufacture of compressed powder medicaments
US4885173A (en) * 1985-05-01 1989-12-05 University Of Utah Methods and compositions for noninvasive dose-to-effect administration of drugs with cardiovascular or renal vascular activities
GB2219206A (en) * 1988-02-03 1989-12-06 Ddsa Pharmaceuticals Ltd Sustained release medicinal formulations containing cellulose ethers
US4940587A (en) * 1985-06-11 1990-07-10 Euroceltique, S.A. Oral pharmaceutical composition through mucosa
US5061493A (en) * 1987-10-08 1991-10-29 Medibrevex Galenical forms of corticoids for administration perlingually and sublingually and process for their preparation
US5122127A (en) * 1985-05-01 1992-06-16 University Of Utah Apparatus and methods for use in administering medicaments by direct medicament contact to mucosal tissues
US5132114A (en) * 1985-05-01 1992-07-21 University Of Utah Research Foundation Compositions and methods of manufacture of compressed powder medicaments
US5288497A (en) * 1985-05-01 1994-02-22 The University Of Utah Compositions of oral dissolvable medicaments
US5713852A (en) * 1995-06-07 1998-02-03 Alza Corporation Oral dosage and method for treating painful conditions of the oral cavity
US5855908A (en) * 1984-05-01 1999-01-05 University Of Utah Research Foundation Non-dissolvable drug-containing dosage-forms for use in the transmucosal delivery of a drug to a patient

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2190409A1 (en) * 1972-06-26 1974-02-01 Lowey Hans
FR2361914A1 (en) * 1975-07-09 1978-03-17 Bayer Ag New formulations of medicines at reduced risk of misuse
US4163777A (en) * 1977-04-29 1979-08-07 Lewis/Howe Company Controlled antacid delivery form and method of treatment therewith
DE3246492A1 (en) * 1981-12-18 1983-06-30 Forest Laboratories A process for the production of therapeutic preparations on the basis of hydroxypropyl methyl cellulose with an extended release pattern
US4680323A (en) * 1983-12-01 1987-07-14 Hans Lowey Method and composition for the preparation of controlled long-acting pharmaceuticals for oral administration
US5855908A (en) * 1984-05-01 1999-01-05 University Of Utah Research Foundation Non-dissolvable drug-containing dosage-forms for use in the transmucosal delivery of a drug to a patient
US5132114A (en) * 1985-05-01 1992-07-21 University Of Utah Research Foundation Compositions and methods of manufacture of compressed powder medicaments
US5288497A (en) * 1985-05-01 1994-02-22 The University Of Utah Compositions of oral dissolvable medicaments
US4863737A (en) * 1985-05-01 1989-09-05 University Of Utah Compositions and methods of manufacture of compressed powder medicaments
US5484602A (en) 1985-05-01 1996-01-16 University Of Utah Research Foundation Methods and compositions for noninvasive dose-to-effect administration of drugs with cardiovascular or renal vascular activities
US4885173A (en) * 1985-05-01 1989-12-05 University Of Utah Methods and compositions for noninvasive dose-to-effect administration of drugs with cardiovascular or renal vascular activities
US5122127A (en) * 1985-05-01 1992-06-16 University Of Utah Apparatus and methods for use in administering medicaments by direct medicament contact to mucosal tissues
US4940587A (en) * 1985-06-11 1990-07-10 Euroceltique, S.A. Oral pharmaceutical composition through mucosa
US4764378A (en) * 1986-02-10 1988-08-16 Zetachron, Inc. Buccal drug dosage form
US4775535A (en) * 1986-04-04 1988-10-04 Hans Lowey Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics
US4855143A (en) * 1986-04-04 1989-08-08 Hans Lowey Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics
US5061493A (en) * 1987-10-08 1991-10-29 Medibrevex Galenical forms of corticoids for administration perlingually and sublingually and process for their preparation
GB2219206A (en) * 1988-02-03 1989-12-06 Ddsa Pharmaceuticals Ltd Sustained release medicinal formulations containing cellulose ethers
US5713852A (en) * 1995-06-07 1998-02-03 Alza Corporation Oral dosage and method for treating painful conditions of the oral cavity

Also Published As

Publication number Publication date
NL142073B (en) 1974-05-15
DE1667888C3 (en) 1978-07-13
BE711241A (en) 1968-07-01
DK122997B (en) 1972-05-08
DE1667888B2 (en) 1977-11-10
NL6802594A (en) 1968-08-26
DE1667888A1 (en) 1971-07-22

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