SE448542B - Bensoheterocykliska foreningar, forfarande for deras framstellning och farmaceutisk komposition derav - Google Patents
Bensoheterocykliska foreningar, forfarande for deras framstellning och farmaceutisk komposition deravInfo
- Publication number
- SE448542B SE448542B SE8106642A SE8106642A SE448542B SE 448542 B SE448542 B SE 448542B SE 8106642 A SE8106642 A SE 8106642A SE 8106642 A SE8106642 A SE 8106642A SE 448542 B SE448542 B SE 448542B
- Authority
- SE
- Sweden
- Prior art keywords
- group
- formula
- compound
- oxo
- grams
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55158652A JPS5781486A (en) | 1980-11-10 | 1980-11-10 | Benzo(ij)quinolidine-2-carboxylic acid derivative |
JP56063170A JPS57176987A (en) | 1981-04-24 | 1981-04-24 | Pyrrolo(3,2,1-ij)quinoline-5-carboxylic acid derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
SE8106642L SE8106642L (sv) | 1982-06-14 |
SE448542B true SE448542B (sv) | 1987-03-02 |
Family
ID=26404260
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8106642A SE448542B (sv) | 1980-11-10 | 1981-11-09 | Bensoheterocykliska foreningar, forfarande for deras framstellning och farmaceutisk komposition derav |
Country Status (19)
Country | Link |
---|---|
US (2) | US4399134A (fr) |
KR (1) | KR880001625B1 (fr) |
AT (2) | AT395150B (fr) |
AU (1) | AU546358B2 (fr) |
CA (1) | CA1179341A (fr) |
CH (1) | CH648845A5 (fr) |
DE (2) | DE10075035I2 (fr) |
DK (1) | DK160940C (fr) |
ES (2) | ES507493A0 (fr) |
FI (1) | FI71141C (fr) |
FR (1) | FR2493849A1 (fr) |
GB (1) | GB2086905B (fr) |
IT (1) | IT1171646B (fr) |
NL (1) | NL193457C (fr) |
NO (1) | NO156828C (fr) |
PH (1) | PH16685A (fr) |
PT (1) | PT73957B (fr) |
SE (1) | SE448542B (fr) |
SU (2) | SU1366055A3 (fr) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO156828C (no) * | 1980-11-10 | 1987-12-02 | Otsuka Pharma Co Ltd | Analogifremgangsm te for fremstilling av antibakterielt virksomme benzoheterocykliske forbindelser. |
US4380543A (en) * | 1981-11-06 | 1983-04-19 | Riker Laboratories, Inc. | Antimicrobial 8-cyano-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acids |
PH22140A (en) * | 1982-06-29 | 1988-06-01 | Daiichi Seiyaku Co | Tricyclic compounds |
US4443447A (en) * | 1982-10-25 | 1984-04-17 | Riker Laboratories, Inc. | Phenyl-substituted tricyclic antibacterial agents |
JPS5978189A (ja) * | 1982-10-26 | 1984-05-04 | Otsuka Pharmaceut Co Ltd | ピロロ〔3,2,1−ij〕キノリン−5−カルボン酸誘導体 |
US4472406A (en) * | 1982-11-12 | 1984-09-18 | Riker Laboratories, Inc. | Antimicrobial 6,7-dihydro-8-(imidazol-1-yl)-5-methyl-1-oxo-1H,5H-benzo [ij]quinolizine-2-carboxylic acids and derivatives |
JPS59137482A (ja) * | 1983-01-26 | 1984-08-07 | Otsuka Pharmaceut Co Ltd | ピロロ〔3,2,1,−ij〕キノリン−5−カルボン酸誘導体 |
JPS59155381A (ja) * | 1983-02-22 | 1984-09-04 | Kyorin Pharmaceut Co Ltd | ベンゾキノリジンカルボン酸誘導体及びその製造法 |
US4473568A (en) * | 1983-03-01 | 1984-09-25 | Warner Lambert Company | Antibacterial thiazolidine or thiomorpholine substituted quinolines |
US4472407A (en) * | 1983-03-17 | 1984-09-18 | Riker Laboratories, Inc. | Antimicrobial 8-alkoxy-6,7-dihydro-5-methyl-9-fluoro-1-oxo-1H,5H-benzo[ij]qu |
US4562195A (en) * | 1984-02-02 | 1985-12-31 | Warner-Lambert Company | Reversing amnesia with saturated tricyclic nitrogen-containing diones |
US4571396A (en) * | 1984-04-16 | 1986-02-18 | Warner-Lambert Company | Antibacterial agents |
US4550103A (en) * | 1984-07-20 | 1985-10-29 | Warner-Lambert Company | Antibacterial 1-oxo-benzoquinolizine-2-carboxylic acids |
CA1253154A (fr) * | 1985-05-24 | 1989-04-25 | Atsushi Takagi | Derives d'acide benzo¬ij|quinolizine-2- carboxylique |
US5210193A (en) * | 1986-01-17 | 1993-05-11 | American Cyanamid Company | Piperazine derivatives |
US4940710A (en) * | 1986-01-17 | 1990-07-10 | American Cyanamid Company | 7-(substituted)piperazinyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids |
US4948894A (en) * | 1989-02-21 | 1990-08-14 | American Cyanamid Company | 8-fluoro and 7, 8, 10-trifluoro-9-(substituted)-6-oxo-6H-benzo-(C)quinolizine-5-carboxylic acids |
KR900014383A (ko) * | 1989-03-29 | 1990-10-23 | 원본미기재 | 피롤로퀴놀린 유도체, 이의 제조방법 및 이를 사용한 항균제 |
US6034100A (en) * | 1993-03-10 | 2000-03-07 | Otsuka Pharmaceutical Co., Ltd. | Method for inhibiting cytokine secretion |
AU676267B2 (en) * | 1993-03-10 | 1997-03-06 | Otsuka Pharmaceutical Co., Ltd. | Interleukin-1 inhibitor |
EP0908181B8 (fr) * | 1996-05-20 | 2009-04-15 | Otsuka Pharmaceutical Co., Ltd. | Remede pour le traitement de l'acne rosacee |
DE19718065A1 (de) * | 1997-04-29 | 1998-11-05 | Henkel Kgaa | Reinigungsmittel für nachvernetzende Polyurethan-Hotmelts |
US6750224B1 (en) | 1999-05-07 | 2004-06-15 | Wockhardt Limited | Antibacterial optically pure benzoquinolizine carboxylic acids, processes, compositions and methods of treatment |
EP2030620A1 (fr) * | 1999-05-07 | 2009-03-04 | Wockhardt Limited | Acides carboxyliques (s)-benzoquinolizines et leur utilisation en tant qu'agents antibactériens |
US6514986B2 (en) | 2000-11-22 | 2003-02-04 | Wockhardt Limited | Chiral fluoroquinolone arginine salt forms |
DE19962470A1 (de) † | 1999-12-22 | 2001-07-12 | Schulz Hans Herrmann | Verwendung von Chemotherapeutika |
US6608078B2 (en) * | 2000-05-08 | 2003-08-19 | Wockhardt Limited | Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment |
WO2001085728A2 (fr) * | 2000-05-08 | 2001-11-15 | Wockhardt Limited | Piperidino-benzo [i, j] quinolizines a substitution de piperidino en 8 chirales antibacteriennes, procedes, compositions et methodes de traitement |
DE60131416T2 (de) * | 2000-05-08 | 2008-09-18 | Wockhardt Ltd. | Chirale fluochinolon-argininsalzformen |
US7098219B2 (en) | 2000-08-01 | 2006-08-29 | Wockhart Limited | Inhibitors of cellular efflux pumps of microbes |
US6878713B2 (en) | 2001-04-25 | 2005-04-12 | Wockhardt Limited | Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments |
US6964966B2 (en) | 2001-04-25 | 2005-11-15 | Wockhardt Limited | Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments |
JP2005511743A (ja) * | 2001-12-13 | 2005-04-28 | ウォックハート・リミテッド | 新世代の三重標的化したキラルな広域スペクトラム抗菌性の7位置換ピペリジノ−キノロンカルボン酸誘導体、その調製方法、組成物、および医薬としての使用 |
WO2003099815A1 (fr) * | 2002-05-28 | 2003-12-04 | Wockhardt Limited | Forme cristalline de sel d'arginine de fluoroquinolone |
EP1918289A3 (fr) | 2002-05-28 | 2009-08-19 | Wockhardt Limited | Forme cristalline de sel d'arginine de fluoroquinolone |
WO2004058262A1 (fr) * | 2002-12-31 | 2004-07-15 | Wockhardt Limited | Compositions contenant de l'acide benzoquinolizine-2-carboxylique |
EP1578449A2 (fr) * | 2002-12-31 | 2005-09-28 | Wockhardt Limited | Compositions de medicaments antibiotiques d'acides carboxyliques benzoquinolizine |
PL214849B1 (pl) * | 2003-09-04 | 2013-09-30 | Wockhardt Ltd | Tetrahydrat soli kwasu benzochinolizyno-2-karboksylowego z arginina, sposób jego wytwarzania, kompozycja zawierajaca przedmiotowy tetrahydrat soli oraz jego zastosowanie |
ATE458737T1 (de) * | 2005-10-21 | 2010-03-15 | Glaxo Group Ltd | Peri-kondensierte tricyclische verbindungen verwendbar als antibakterielle mittel |
JP6240063B2 (ja) | 2011-04-28 | 2017-11-29 | ザ ブロード インスティテュート, インコーポレイテッド | ヒストンデアセチラーゼ阻害剤 |
WO2014018979A1 (fr) | 2012-07-27 | 2014-01-30 | The Broad Institute, Inc. | Inhibiteurs d'histone-désacétylases |
US9914717B2 (en) | 2012-12-20 | 2018-03-13 | The Broad Institute, Inc. | Cycloalkenyl hydroxamic acid derivatives and their use as histone deacetylase inhibitors |
BR112016008378B1 (pt) | 2013-10-14 | 2022-11-08 | Eisai R&D Management Co., Ltd | Compostos de quinolina seletivamente substituídos ou sal dos mesmos, e composição farmacêutica contendo os ditos compostos |
WO2015057659A1 (fr) | 2013-10-14 | 2015-04-23 | Eisai R&D Management Co., Ltd. | Composés de quinoline sélectivement substitués |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE793524A (fr) * | 1971-12-30 | 1973-06-29 | Riker Laboratories Inc | Acides benzoquinolizine-carboxyliques et leurs derives |
US4001243A (en) * | 1972-11-02 | 1977-01-04 | Riker Laboratories, Inc. | Substituted benzo(ij)quinolizine-2-carboxylic acids and derivatives thereof |
US3917609A (en) * | 1973-06-27 | 1975-11-04 | Minnesota Mining & Mfg | Pyrroloquinoline carboxylic acids and derivatives |
JPS6019910B2 (ja) * | 1979-10-11 | 1985-05-18 | 大塚製薬株式会社 | ベンゾ〔ij〕キノリジン−2−カルボン酸誘導体及びその製造法 |
DE2953974C2 (fr) * | 1978-04-12 | 1992-06-25 | Otsuka Pharmaceutical Co., Ltd., Tokio/Tokyo, Jp | |
US4416884A (en) * | 1978-04-12 | 1983-11-22 | Otsuka Pharmaceutical Co., Ltd. | Piperazinylbenzoheterocyclic compounds |
JPS5540616A (en) * | 1978-09-14 | 1980-03-22 | Otsuka Pharmaceut Co Ltd | Preparation of benzo-hetero-compound |
JPS5630964A (en) * | 1979-08-22 | 1981-03-28 | Kyorin Pharmaceut Co Ltd | Novel substituted quinolinecarboxylic acid and its preparation |
JPS55149284A (en) * | 1980-05-02 | 1980-11-20 | Otsuka Pharmaceut Co Ltd | Piperazinylbenzo heterocyclic derivative |
NO156828C (no) * | 1980-11-10 | 1987-12-02 | Otsuka Pharma Co Ltd | Analogifremgangsm te for fremstilling av antibakterielt virksomme benzoheterocykliske forbindelser. |
AT380250B (de) * | 1980-12-18 | 1986-04-25 | Otsuka Pharma Co Ltd | Verfahren zur herstellung benzoheterocyclischer verbindungen |
-
1981
- 1981-11-04 NO NO813726A patent/NO156828C/no not_active IP Right Cessation
- 1981-11-05 AT AT0474881A patent/AT395150B/de not_active IP Right Cessation
- 1981-11-09 IT IT49656/81A patent/IT1171646B/it active
- 1981-11-09 PT PT73957A patent/PT73957B/pt unknown
- 1981-11-09 DK DK495281A patent/DK160940C/da not_active IP Right Cessation
- 1981-11-09 DE DE2000175035 patent/DE10075035I2/de active Active
- 1981-11-09 SU SU813354800A patent/SU1366055A3/ru active
- 1981-11-09 SE SE8106642A patent/SE448542B/sv unknown
- 1981-11-09 DE DE19813144455 patent/DE3144455A1/de active Granted
- 1981-11-09 FI FI813526A patent/FI71141C/fi not_active IP Right Cessation
- 1981-11-10 FR FR8121100A patent/FR2493849A1/fr active Granted
- 1981-11-10 US US06/320,027 patent/US4399134A/en not_active Expired - Lifetime
- 1981-11-10 ES ES507493A patent/ES507493A0/es active Granted
- 1981-11-10 GB GB8133890A patent/GB2086905B/en not_active Expired
- 1981-11-10 CH CH7200/81A patent/CH648845A5/de not_active IP Right Cessation
- 1981-11-10 CA CA000389769A patent/CA1179341A/fr not_active Expired
- 1981-11-10 KR KR1019810004344A patent/KR880001625B1/ko active
- 1981-11-10 PH PH26477A patent/PH16685A/en unknown
- 1981-11-10 AU AU77335/81A patent/AU546358B2/en not_active Expired
- 1981-11-10 NL NL8105075A patent/NL193457C/nl not_active IP Right Cessation
-
1982
- 1982-10-15 ES ES516523A patent/ES8401035A1/es not_active Expired
- 1982-12-27 SU SU823527501A patent/SU1277896A3/ru active
-
1983
- 1983-05-25 US US06/497,914 patent/US4552879A/en not_active Expired - Lifetime
-
1989
- 1989-12-20 AT AT2887/89A patent/AT393383B/de not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SE448542B (sv) | Bensoheterocykliska foreningar, forfarande for deras framstellning och farmaceutisk komposition derav | |
FI66379B (fi) | Analogifoerfarande foer framstaellning av terapeutiskt anvaendbara 6-halogen-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1-substituerade 1,8-naftyridin-3-karboxylsyror och salter daerav | |
US4416884A (en) | Piperazinylbenzoheterocyclic compounds | |
KR880002353B1 (ko) | 퀴놀린 화합물 및 그의 제조방법 | |
HU199821B (en) | Process for production of derivatives of in 8 position substituated quinoline carbonic acid and medical compositions containing them | |
JPH0141127B2 (fr) | ||
JPH07309864A (ja) | 5−アミノ−8−メチル−7−ピロリジニルキノリン−3−カルボン酸誘導体 | |
EP0195316A1 (fr) | Dérivés de l'acide quinolonecarboxylique | |
CA1153374A (fr) | Composes piperazinylbenzoheterocycliques | |
CA1156232A (fr) | Acides benzo(ij)quinolizine-2-carboxyliques, compositions therapeutiques qui en renferment, et methode d'obtention | |
Sanchez et al. | New 8-(trifluoromethyl)-substituted quinolones. The benefits of the 8-fluoro group with reduced phototoxic risk | |
JPS647996B2 (fr) | ||
JPS6237628B2 (fr) | ||
US8158646B2 (en) | Antifungal and antiparasitic indoloquinoline derivates | |
EP0319906A2 (fr) | Dérivés de la quinoléine, procédé de leur préparation et agent antibactérien les contenant | |
JPH02191257A (ja) | ベンゾヘテロ環化合物 | |
Remuzon et al. | Fluoronaphthyridines and-quinolones as antibacterial agents. 3. Synthesis and structure-activity relationships of new 1-(1, 1-dimethyl-2-fluoroethyl), 1-[1-methyl-1-(fluoromethyl)-2-fluoroethyl], and 1-[1, 1-(difluoromethyl)-2-fluoroethyl] substituted derivatives | |
FI70219B (fi) | Foerfarande foer framstaellning av en beta-laktamantibiotikumfoerening | |
EP0315827A1 (fr) | Dérivés de l'acide quinolinecarboxylique | |
EP0339406A1 (fr) | Dérivés de l'acide quinoline-3-carboxylique, procédé pour leur préparation et composition antibactérienne les contenant | |
FI66612C (fi) | Foerfarande foer framstaellning av nya saosom antimicrobica anaendbara piperazinylbensoheterocykliska foereningar | |
JPH0559052A (ja) | 新規三環性化合物又はその塩及びこれを含有する抗菌剤 | |
JPH037674B2 (fr) | ||
JPS622598B2 (fr) | ||
ITMI951593A1 (it) | Derivati chinolonici non fluorurati e loro impiego come agenti antibatterici |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
NAL | Patent in force |
Ref document number: 8106642-5 Format of ref document f/p: F |