JPS55149284A - Piperazinylbenzo heterocyclic derivative - Google Patents

Piperazinylbenzo heterocyclic derivative

Info

Publication number
JPS55149284A
JPS55149284A JP5912180A JP5912180A JPS55149284A JP S55149284 A JPS55149284 A JP S55149284A JP 5912180 A JP5912180 A JP 5912180A JP 5912180 A JP5912180 A JP 5912180A JP S55149284 A JPS55149284 A JP S55149284A
Authority
JP
Japan
Prior art keywords
formula
halogen
heterocyclic derivative
antibacterial
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP5912180A
Other languages
Japanese (ja)
Other versions
JPS6232194B2 (en
Inventor
Hiroshi Ishikawa
Fujio Tafusa
Kazuyuki Nakagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP5912180A priority Critical patent/JPS55149284A/en
Publication of JPS55149284A publication Critical patent/JPS55149284A/en
Publication of JPS6232194B2 publication Critical patent/JPS6232194B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

NEW MATERIAL:A piperazinylbenzoheterocyclic derivative of formula I [R<1> is H, lower alkyl, lower alkanoyl, phenylalkyl group, etc.; R<2> is H or halogen; -A- is -(CH2)n-CHR<3>-(R<3> is H or lower alkyl group; n is 1 or 2], or its salt. EXAMPLE:8-(1-Piperazinyl)-6, 7-dihydro-1-oxo-1H, 5H-benzo[i,j]quinolizine-2-carboxylic acid. USE:An antibacterial, external bactericide, and disinfectant having an antibacterial acitivity against Gram-positive and Gram-negative bacteria in a low concentration. PROCESS:A benzo heterocyclic derivative of formula II (R<4> is halogen, lower alkanesulfonyloxy group, etc.) is reacted with a piperazine of formula III in the presence of a deacidification agent, e.g. sodium carbonate, in an inert solvent, e.g. dimethyl sulfoxide, to give the compound of formula I.
JP5912180A 1980-05-02 1980-05-02 Piperazinylbenzo heterocyclic derivative Granted JPS55149284A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP5912180A JPS55149284A (en) 1980-05-02 1980-05-02 Piperazinylbenzo heterocyclic derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5912180A JPS55149284A (en) 1980-05-02 1980-05-02 Piperazinylbenzo heterocyclic derivative

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2720479A Division JPS55118416A (en) 1979-03-07 1979-03-07 Antibacterial agent

Publications (2)

Publication Number Publication Date
JPS55149284A true JPS55149284A (en) 1980-11-20
JPS6232194B2 JPS6232194B2 (en) 1987-07-13

Family

ID=13104153

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5912180A Granted JPS55149284A (en) 1980-05-02 1980-05-02 Piperazinylbenzo heterocyclic derivative

Country Status (1)

Country Link
JP (1) JPS55149284A (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57102887A (en) * 1980-12-18 1982-06-26 Otsuka Pharmaceut Co Ltd Preparation of benzo(ij)quinolizine-2-carboxylic acid derivative
JPS57176987A (en) * 1981-04-24 1982-10-30 Otsuka Pharmaceut Co Ltd Pyrrolo(3,2,1-ij)quinoline-5-carboxylic acid derivative
JPS5813585A (en) * 1981-07-15 1983-01-26 Otsuka Pharmaceut Co Ltd Pyrroloquinolinecarboxylic acid derivative
JPS5855484A (en) * 1981-09-25 1983-04-01 Otsuka Pharmaceut Co Ltd Preparation of pyrrolo(3,2,1-ij)quinoline-5-carboxylic acid derivative
JPS59137482A (en) * 1983-01-26 1984-08-07 Otsuka Pharmaceut Co Ltd Pyrrolo(3,2,1,-ij)quinoline-5-carboxylic acid derivative
US4552879A (en) * 1980-11-10 1985-11-12 Otsuka Pharmaceutical Co., Ltd. Benzoheterocyclic compounds and pharmaceutical composition thereof
JP4621356B2 (en) * 1999-02-05 2011-01-26 富山化学工業株式会社 Tricyclic quinolonecarboxylic acid derivative or salt thereof
CN108349968A (en) * 2015-07-28 2018-07-31 维奥梅生物科学私人有限公司 Antibacterial therapy agent and prophylactic

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2503302Y2 (en) * 1989-08-09 1996-06-26 立川ブラインド工業株式会社 Roll blind operating device
CN111269863B (en) * 2020-03-17 2022-06-10 山东中农普宁药业有限公司 Pseudomonas and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5576875A (en) * 1978-08-31 1980-06-10 Otsuka Pharmaceut Co Ltd Benzo ij quinolizine-2-carboxylic acid derivative and its preparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5576875A (en) * 1978-08-31 1980-06-10 Otsuka Pharmaceut Co Ltd Benzo ij quinolizine-2-carboxylic acid derivative and its preparation

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4552879A (en) * 1980-11-10 1985-11-12 Otsuka Pharmaceutical Co., Ltd. Benzoheterocyclic compounds and pharmaceutical composition thereof
JPS57102887A (en) * 1980-12-18 1982-06-26 Otsuka Pharmaceut Co Ltd Preparation of benzo(ij)quinolizine-2-carboxylic acid derivative
JPS57176987A (en) * 1981-04-24 1982-10-30 Otsuka Pharmaceut Co Ltd Pyrrolo(3,2,1-ij)quinoline-5-carboxylic acid derivative
JPH0222074B2 (en) * 1981-04-24 1990-05-17 Otsuka Pharma Co Ltd
JPS5813585A (en) * 1981-07-15 1983-01-26 Otsuka Pharmaceut Co Ltd Pyrroloquinolinecarboxylic acid derivative
JPH0129795B2 (en) * 1981-07-15 1989-06-14 Otsuka Pharma Co Ltd
JPS5855484A (en) * 1981-09-25 1983-04-01 Otsuka Pharmaceut Co Ltd Preparation of pyrrolo(3,2,1-ij)quinoline-5-carboxylic acid derivative
JPS59137482A (en) * 1983-01-26 1984-08-07 Otsuka Pharmaceut Co Ltd Pyrrolo(3,2,1,-ij)quinoline-5-carboxylic acid derivative
JPH0321031B2 (en) * 1983-01-26 1991-03-20 Otsuka Pharma Co Ltd
JP4621356B2 (en) * 1999-02-05 2011-01-26 富山化学工業株式会社 Tricyclic quinolonecarboxylic acid derivative or salt thereof
CN108349968A (en) * 2015-07-28 2018-07-31 维奥梅生物科学私人有限公司 Antibacterial therapy agent and prophylactic
JP2018528260A (en) * 2015-07-28 2018-09-27 ビオーム バイオサイエンシズ プライベート リミティド Antibacterial therapeutics and preventives

Also Published As

Publication number Publication date
JPS6232194B2 (en) 1987-07-13

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