JPS6470483A - Quinoline-3-carboxylic acid derivative - Google Patents

Quinoline-3-carboxylic acid derivative

Info

Publication number
JPS6470483A
JPS6470483A JP22643487A JP22643487A JPS6470483A JP S6470483 A JPS6470483 A JP S6470483A JP 22643487 A JP22643487 A JP 22643487A JP 22643487 A JP22643487 A JP 22643487A JP S6470483 A JPS6470483 A JP S6470483A
Authority
JP
Japan
Prior art keywords
carboxylic acid
acid derivative
quinoline
formula
fluorophenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP22643487A
Other languages
Japanese (ja)
Inventor
Yasuo Ito
Hideo Kato
Eiichi Ecchu
Nobuo Ogawa
Kazuya Mitani
Noriyuki Yagi
Toshihiko Yoshida
Tomio Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Japan Co Ltd
Original Assignee
Hokuriku Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hokuriku Pharmaceutical Co Ltd filed Critical Hokuriku Pharmaceutical Co Ltd
Priority to JP22643487A priority Critical patent/JPS6470483A/en
Publication of JPS6470483A publication Critical patent/JPS6470483A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:A compound expressed by formula I (R1 and R2 are H or halogen; R3 is H or lower alkyl) and salt thereof. EXAMPLE:6, 8-Difluoro-7-(3-fluoromethyl-1-piperazinyl)-1-(4-fluorophenyl)-1,4-dihy dro-4-oxoquinoline-3-carboxylic acid.hydrochloride. USE:An antimicrobial agent. PREPARATION:A 7-halogenoquinoline-3-carboxylic acid derivative expressed by formula II (X is halogen) [e.g. 6,7,8-trifluoro-1-(4-fluorophenyl)-1,4-dihydro-4- oxoquinoli-ne-3-carboxylic acid] is reacted with a piperazine derivative expressed by formula III (e.g. 2-fluoromethylpiperazine), as necessary, in the presence of a solvent and abase as a deacidifying agent.
JP22643487A 1987-09-11 1987-09-11 Quinoline-3-carboxylic acid derivative Pending JPS6470483A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP22643487A JPS6470483A (en) 1987-09-11 1987-09-11 Quinoline-3-carboxylic acid derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP22643487A JPS6470483A (en) 1987-09-11 1987-09-11 Quinoline-3-carboxylic acid derivative

Publications (1)

Publication Number Publication Date
JPS6470483A true JPS6470483A (en) 1989-03-15

Family

ID=16845052

Family Applications (1)

Application Number Title Priority Date Filing Date
JP22643487A Pending JPS6470483A (en) 1987-09-11 1987-09-11 Quinoline-3-carboxylic acid derivative

Country Status (1)

Country Link
JP (1) JPS6470483A (en)

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