JPS6470483A - Quinoline-3-carboxylic acid derivative - Google Patents
Quinoline-3-carboxylic acid derivativeInfo
- Publication number
- JPS6470483A JPS6470483A JP22643487A JP22643487A JPS6470483A JP S6470483 A JPS6470483 A JP S6470483A JP 22643487 A JP22643487 A JP 22643487A JP 22643487 A JP22643487 A JP 22643487A JP S6470483 A JPS6470483 A JP S6470483A
- Authority
- JP
- Japan
- Prior art keywords
- carboxylic acid
- acid derivative
- quinoline
- formula
- fluorophenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:A compound expressed by formula I (R1 and R2 are H or halogen; R3 is H or lower alkyl) and salt thereof. EXAMPLE:6, 8-Difluoro-7-(3-fluoromethyl-1-piperazinyl)-1-(4-fluorophenyl)-1,4-dihy dro-4-oxoquinoline-3-carboxylic acid.hydrochloride. USE:An antimicrobial agent. PREPARATION:A 7-halogenoquinoline-3-carboxylic acid derivative expressed by formula II (X is halogen) [e.g. 6,7,8-trifluoro-1-(4-fluorophenyl)-1,4-dihydro-4- oxoquinoli-ne-3-carboxylic acid] is reacted with a piperazine derivative expressed by formula III (e.g. 2-fluoromethylpiperazine), as necessary, in the presence of a solvent and abase as a deacidifying agent.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP22643487A JPS6470483A (en) | 1987-09-11 | 1987-09-11 | Quinoline-3-carboxylic acid derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP22643487A JPS6470483A (en) | 1987-09-11 | 1987-09-11 | Quinoline-3-carboxylic acid derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6470483A true JPS6470483A (en) | 1989-03-15 |
Family
ID=16845052
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP22643487A Pending JPS6470483A (en) | 1987-09-11 | 1987-09-11 | Quinoline-3-carboxylic acid derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6470483A (en) |
-
1987
- 1987-09-11 JP JP22643487A patent/JPS6470483A/en active Pending
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