SE447574B - Inklusionskomplex av prostacyklin-metylester och beta-cyklodextrin, sett for dess framstellning samt lekemedelsberedning baserad derpa - Google Patents

Inklusionskomplex av prostacyklin-metylester och beta-cyklodextrin, sett for dess framstellning samt lekemedelsberedning baserad derpa

Info

Publication number
SE447574B
SE447574B SE7809946A SE7809946A SE447574B SE 447574 B SE447574 B SE 447574B SE 7809946 A SE7809946 A SE 7809946A SE 7809946 A SE7809946 A SE 7809946A SE 447574 B SE447574 B SE 447574B
Authority
SE
Sweden
Prior art keywords
prostacyclin
cyclodextrin
methyl ester
inclusion complex
solution
Prior art date
Application number
SE7809946A
Other languages
English (en)
Swedish (sv)
Other versions
SE7809946L (sv
Inventor
J Szejtli
M Szejtli
G Cseh
I Stadler
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of SE7809946L publication Critical patent/SE7809946L/xx
Publication of SE447574B publication Critical patent/SE447574B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medical Informatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE7809946A 1977-09-23 1978-09-21 Inklusionskomplex av prostacyklin-metylester och beta-cyklodextrin, sett for dess framstellning samt lekemedelsberedning baserad derpa SE447574B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77CI1770A HU179141B (da) 1977-09-23 1977-09-23

Publications (2)

Publication Number Publication Date
SE7809946L SE7809946L (sv) 1979-03-24
SE447574B true SE447574B (sv) 1986-11-24

Family

ID=10994670

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7809946A SE447574B (sv) 1977-09-23 1978-09-21 Inklusionskomplex av prostacyklin-metylester och beta-cyklodextrin, sett for dess framstellning samt lekemedelsberedning baserad derpa

Country Status (20)

Country Link
JP (1) JPS5456685A (da)
AT (1) AT369362B (da)
BE (1) BE870646A (da)
CH (1) CH637388A5 (da)
CS (1) CS200242B2 (da)
DD (1) DD138600A5 (da)
DE (1) DE2840142A1 (da)
DK (1) DK420778A (da)
FI (1) FI65912C (da)
FR (1) FR2404006A1 (da)
GB (1) GB2006193B (da)
GR (1) GR65001B (da)
HU (1) HU179141B (da)
IL (1) IL55569A (da)
IT (1) IT1160661B (da)
NL (1) NL7809643A (da)
PL (1) PL121664B1 (da)
SE (1) SE447574B (da)
SU (1) SU847914A3 (da)
YU (1) YU220678A (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53136513A (en) * 1977-05-06 1978-11-29 Ono Pharmaceut Co Ltd Stabilization of prostaglandin-x-related compounds
US4352793A (en) * 1979-04-26 1982-10-05 Sumitomo Chemical Company, Limited Pharmaceutical composition comprising bencyclane fumarate and cyclodextrin
JPS5920230A (ja) * 1982-07-19 1984-02-01 チバ−ガイギ−・アクチエンゲゼルシヤフト ピルプロフエン含有薬剤
JPS61289034A (ja) * 1985-06-17 1986-12-19 Teijin Ltd イソカルバサイクリン類脂肪乳剤
DE3608088C2 (de) * 1986-03-07 1995-11-16 Schering Ag Pharmazeutische Präparate, enthaltend Cyclodextrinclathrate von Carbacyclinderivaten
DE3740838A1 (de) * 1987-11-27 1989-06-08 Schering Ag Cyclodextrinclathrate von 5-cyano-prostacyclinderivaten und ihre verwendung als arzneimittel
KR20060127946A (ko) * 2004-01-29 2006-12-13 에자이 알앤드디 매니지먼트 가부시키가이샤 매크롤라이드계 화합물의 안정화 방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS503362B1 (da) * 1970-06-10 1975-02-04
US3953435A (en) * 1974-01-10 1976-04-27 Ono Pharmaceutical Company Aldehyde derivatives of prostaglandins
JPS5395958A (en) * 1977-01-31 1978-08-22 Ono Pharmaceut Co Ltd Prostaglandin analogues and process for their preparation
US4178367A (en) * 1977-02-21 1979-12-11 Ono Pharmaceutical Co. Ltd. Prostaglandin I2 analogues
JPS53136513A (en) * 1977-05-06 1978-11-29 Ono Pharmaceut Co Ltd Stabilization of prostaglandin-x-related compounds

Also Published As

Publication number Publication date
GB2006193A (en) 1979-05-02
CH637388A5 (de) 1983-07-29
SE7809946L (sv) 1979-03-24
GB2006193B (en) 1982-05-26
FI782878A (fi) 1979-03-24
IL55569A0 (en) 1978-12-17
PL121664B1 (en) 1982-05-31
DD138600A5 (de) 1979-11-14
IL55569A (en) 1981-12-31
NL7809643A (nl) 1979-03-27
ATA677478A (de) 1982-05-15
CS200242B2 (en) 1980-08-29
AT369362B (de) 1982-12-27
FI65912C (fi) 1984-08-10
YU220678A (en) 1983-10-31
FR2404006A1 (fr) 1979-04-20
GR65001B (en) 1980-06-12
IT7869160A0 (it) 1978-09-19
SU847914A3 (ru) 1981-07-15
PL209773A1 (pl) 1979-06-04
FI65912B (fi) 1984-04-30
JPS5456685A (en) 1979-05-07
FR2404006B1 (da) 1981-07-31
HU179141B (da) 1982-08-28
BE870646A (fr) 1979-01-15
IT1160661B (it) 1987-03-11
DE2840142A1 (de) 1979-04-05
DK420778A (da) 1979-03-24

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