AT369362B - Verfahren zur herstellung von neuen cyclodextrin- einschlusskomplexen des prostacyclins und dessen derivaten - Google Patents

Verfahren zur herstellung von neuen cyclodextrin- einschlusskomplexen des prostacyclins und dessen derivaten

Info

Publication number
AT369362B
AT369362B AT0677478A AT677478A AT369362B AT 369362 B AT369362 B AT 369362B AT 0677478 A AT0677478 A AT 0677478A AT 677478 A AT677478 A AT 677478A AT 369362 B AT369362 B AT 369362B
Authority
AT
Austria
Prior art keywords
prostacycline
derivatives
cyclodextrin inclusion
inclusion complexes
producing new
Prior art date
Application number
AT0677478A
Other languages
German (de)
English (en)
Other versions
ATA677478A (de
Inventor
Jozsef Dr Dipl Ing Che Szejtli
Magdolna Dr Szejtli
Gyoergy Dr Cseh
Istvan Dr Stadler
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of ATA677478A publication Critical patent/ATA677478A/de
Application granted granted Critical
Publication of AT369362B publication Critical patent/AT369362B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT0677478A 1977-09-23 1978-09-20 Verfahren zur herstellung von neuen cyclodextrin- einschlusskomplexen des prostacyclins und dessen derivaten AT369362B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77CI1770A HU179141B (da) 1977-09-23 1977-09-23

Publications (2)

Publication Number Publication Date
ATA677478A ATA677478A (de) 1982-05-15
AT369362B true AT369362B (de) 1982-12-27

Family

ID=10994670

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0677478A AT369362B (de) 1977-09-23 1978-09-20 Verfahren zur herstellung von neuen cyclodextrin- einschlusskomplexen des prostacyclins und dessen derivaten

Country Status (20)

Country Link
JP (1) JPS5456685A (da)
AT (1) AT369362B (da)
BE (1) BE870646A (da)
CH (1) CH637388A5 (da)
CS (1) CS200242B2 (da)
DD (1) DD138600A5 (da)
DE (1) DE2840142A1 (da)
DK (1) DK420778A (da)
FI (1) FI65912C (da)
FR (1) FR2404006A1 (da)
GB (1) GB2006193B (da)
GR (1) GR65001B (da)
HU (1) HU179141B (da)
IL (1) IL55569A (da)
IT (1) IT1160661B (da)
NL (1) NL7809643A (da)
PL (1) PL121664B1 (da)
SE (1) SE447574B (da)
SU (1) SU847914A3 (da)
YU (1) YU220678A (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53136513A (en) * 1977-05-06 1978-11-29 Ono Pharmaceut Co Ltd Stabilization of prostaglandin-x-related compounds
US4352793A (en) * 1979-04-26 1982-10-05 Sumitomo Chemical Company, Limited Pharmaceutical composition comprising bencyclane fumarate and cyclodextrin
JPS5920230A (ja) * 1982-07-19 1984-02-01 チバ−ガイギ−・アクチエンゲゼルシヤフト ピルプロフエン含有薬剤
JPS61289034A (ja) * 1985-06-17 1986-12-19 Teijin Ltd イソカルバサイクリン類脂肪乳剤
DE3608088C2 (de) * 1986-03-07 1995-11-16 Schering Ag Pharmazeutische Präparate, enthaltend Cyclodextrinclathrate von Carbacyclinderivaten
DE3740838A1 (de) * 1987-11-27 1989-06-08 Schering Ag Cyclodextrinclathrate von 5-cyano-prostacyclinderivaten und ihre verwendung als arzneimittel
JPWO2005073223A1 (ja) * 2004-01-29 2007-09-13 エーザイ・アール・アンド・ディー・マネジメント株式会社 マクロライド系化合物の安定化方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS503362B1 (da) * 1970-06-10 1975-02-04
US3953435A (en) * 1974-01-10 1976-04-27 Ono Pharmaceutical Company Aldehyde derivatives of prostaglandins
JPS5395958A (en) * 1977-01-31 1978-08-22 Ono Pharmaceut Co Ltd Prostaglandin analogues and process for their preparation
US4178367A (en) * 1977-02-21 1979-12-11 Ono Pharmaceutical Co. Ltd. Prostaglandin I2 analogues
JPS53136513A (en) * 1977-05-06 1978-11-29 Ono Pharmaceut Co Ltd Stabilization of prostaglandin-x-related compounds

Also Published As

Publication number Publication date
SE7809946L (sv) 1979-03-24
PL209773A1 (pl) 1979-06-04
PL121664B1 (en) 1982-05-31
SE447574B (sv) 1986-11-24
DE2840142A1 (de) 1979-04-05
IT7869160A0 (it) 1978-09-19
FI782878A (fi) 1979-03-24
FR2404006B1 (da) 1981-07-31
JPS5456685A (en) 1979-05-07
HU179141B (da) 1982-08-28
GB2006193A (en) 1979-05-02
SU847914A3 (ru) 1981-07-15
CS200242B2 (en) 1980-08-29
DD138600A5 (de) 1979-11-14
DK420778A (da) 1979-03-24
GR65001B (en) 1980-06-12
FI65912B (fi) 1984-04-30
BE870646A (fr) 1979-01-15
IT1160661B (it) 1987-03-11
NL7809643A (nl) 1979-03-27
YU220678A (en) 1983-10-31
IL55569A0 (en) 1978-12-17
FI65912C (fi) 1984-08-10
ATA677478A (de) 1982-05-15
GB2006193B (en) 1982-05-26
CH637388A5 (de) 1983-07-29
FR2404006A1 (fr) 1979-04-20
IL55569A (en) 1981-12-31

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Legal Events

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ELJ Ceased due to non-payment of the annual fee