SE436206B - Penicillansyra-1,1-dioxider med antibakteriell verkan - Google Patents

Penicillansyra-1,1-dioxider med antibakteriell verkan

Info

Publication number
SE436206B
SE436206B SE7806628A SE7806628A SE436206B SE 436206 B SE436206 B SE 436206B SE 7806628 A SE7806628 A SE 7806628A SE 7806628 A SE7806628 A SE 7806628A SE 436206 B SE436206 B SE 436206B
Authority
SE
Sweden
Prior art keywords
penicillanate
dioxide
oxide
acid
penicillanic acid
Prior art date
Application number
SE7806628A
Other languages
English (en)
Swedish (sv)
Other versions
SE7806628L (sv
Inventor
W E Barth
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27122691&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE436206(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of SE7806628L publication Critical patent/SE7806628L/xx
Publication of SE436206B publication Critical patent/SE436206B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SE7806628A 1977-06-07 1978-06-06 Penicillansyra-1,1-dioxider med antibakteriell verkan SE436206B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80432077A 1977-06-07 1977-06-07
US87938178A 1978-02-21 1978-02-21

Publications (2)

Publication Number Publication Date
SE7806628L SE7806628L (sv) 1978-12-08
SE436206B true SE436206B (sv) 1984-11-19

Family

ID=27122691

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7806628A SE436206B (sv) 1977-06-07 1978-06-06 Penicillansyra-1,1-dioxider med antibakteriell verkan
SE8305916A SE447995B (sv) 1977-06-07 1983-10-27 Mellanprodukt for framstellning av pencillansyra-1,1-dioxider

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE8305916A SE447995B (sv) 1977-06-07 1983-10-27 Mellanprodukt for framstellning av pencillansyra-1,1-dioxider

Country Status (35)

Country Link
AR (1) AR224111A1 (US07968547-20110628-C00004.png)
AT (2) AT360649B (US07968547-20110628-C00004.png)
AU (1) AU513636B2 (US07968547-20110628-C00004.png)
BE (1) BE867859A (US07968547-20110628-C00004.png)
BG (2) BG34615A3 (US07968547-20110628-C00004.png)
CH (1) CH634073A5 (US07968547-20110628-C00004.png)
CS (1) CS208472B2 (US07968547-20110628-C00004.png)
DD (2) DD140888A5 (US07968547-20110628-C00004.png)
DE (2) DE2857263C3 (US07968547-20110628-C00004.png)
DK (1) DK155740C (US07968547-20110628-C00004.png)
EG (1) EG13869A (US07968547-20110628-C00004.png)
FI (1) FI66003C (US07968547-20110628-C00004.png)
FR (2) FR2393804A1 (US07968547-20110628-C00004.png)
GB (1) GB2000138B (US07968547-20110628-C00004.png)
GR (1) GR72255B (US07968547-20110628-C00004.png)
HK (1) HK13184A (US07968547-20110628-C00004.png)
HU (1) HU180042B (US07968547-20110628-C00004.png)
IE (1) IE47079B1 (US07968547-20110628-C00004.png)
IL (2) IL54867A (US07968547-20110628-C00004.png)
IN (1) IN149747B (US07968547-20110628-C00004.png)
IT (1) IT1096381B (US07968547-20110628-C00004.png)
KE (1) KE3355A (US07968547-20110628-C00004.png)
LU (1) LU79774A1 (US07968547-20110628-C00004.png)
MY (1) MY8500092A (US07968547-20110628-C00004.png)
NL (2) NL180009C (US07968547-20110628-C00004.png)
NO (2) NO151746C (US07968547-20110628-C00004.png)
NZ (1) NZ187476A (US07968547-20110628-C00004.png)
OA (1) OA05964A (US07968547-20110628-C00004.png)
PH (3) PH26810A (US07968547-20110628-C00004.png)
PL (1) PL114501B1 (US07968547-20110628-C00004.png)
PT (1) PT68146A (US07968547-20110628-C00004.png)
SE (2) SE436206B (US07968547-20110628-C00004.png)
SG (1) SG65383G (US07968547-20110628-C00004.png)
SU (1) SU860706A1 (US07968547-20110628-C00004.png)
YU (1) YU41829B (US07968547-20110628-C00004.png)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU77306A1 (US07968547-20110628-C00004.png) * 1977-05-09 1979-01-18
DE2912511C2 (de) * 1977-06-07 1982-06-24 Pfizer Inc., 10017 New York, N.Y. Pharmazeutische Zusammensetzung, enthaltend Penicillansäure
DK155942C (da) * 1977-12-23 1989-10-23 Pfizer Analogifremgangsmaade til fremstilling af 6-aminopenicillansyre-1,1-dioxid og fysiologisk acceptable syreadditions- og basesalte deraf.
JPS54126735A (en) * 1978-03-24 1979-10-02 Toyama Chem Co Ltd Bactericidal composition for medical use
US4241050A (en) * 1978-09-01 1980-12-23 Pfizer Inc. Penam 1,1-dioxides as beta-lactamase inhibitors
CA1158639A (en) * 1978-12-11 1983-12-13 Eric M. Gordon 6-bromopenicillanic acid sulfone
IE49881B1 (en) * 1979-02-13 1986-01-08 Leo Pharm Prod Ltd B-lactam intermediates
US4714761A (en) * 1979-03-05 1987-12-22 Pfizer Inc. 6,6-dihalopenicillanic acid 1,1-dioxides and process
US4420426A (en) 1979-03-05 1983-12-13 Pfizer Inc. 6-Alpha-halopenicillanic acid 1,1-dioxides
SE449103B (sv) * 1979-03-05 1987-04-06 Pfizer Sett att framstella penicillansyra-1,1-dioxid samt estrar derav
GB2045236A (en) * 1979-03-26 1980-10-29 Hoechst Uk Ltd Oxapenem derivatives
US4244951A (en) * 1979-05-16 1981-01-13 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
US4309347A (en) * 1979-05-16 1982-01-05 Pfizer Inc. Penicillanoyloxymethyl penicillanate 1,1,1',1'-tetraoxide
IE49770B1 (en) * 1979-05-21 1985-12-11 Leo Pharm Prod Ltd 6beta-halopenicillanic acid derivatives
DE3051044C2 (US07968547-20110628-C00004.png) * 1979-06-19 1989-03-30 Leo Pharmaceutical Products Ltd. A/S (Loevens Kemiske Fabrik Produktionsaktieselskab), Ballerup, Dk
US4256733A (en) * 1979-09-26 1981-03-17 Pfizer Inc. Acetoxymethyl penam compounds as β-lactamase inhibitors
US4432970A (en) * 1979-11-23 1984-02-21 Pfizer Inc. 6-beta-Halopenicillanic acid 1,1-dioxides as beta-lactamase inhibitors
IL61880A (en) * 1980-01-21 1984-11-30 Bristol Myers Co 2beta-chloromethyl-2alpha-methylpenam-3alpha-carboxylic acid sulfone derivatives,their preparation and pharmaceutical compositions containing them
US4488994A (en) * 1980-09-08 1984-12-18 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
US4432903A (en) * 1980-09-08 1984-02-21 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
US4474698A (en) * 1980-12-11 1984-10-02 Pfizer Inc. Process for preparing esters of penicillanic acid sulfone
US4419284A (en) * 1981-03-23 1983-12-06 Pfizer Inc. Preparation of halomethyl esters (and related esters) of penicillanic acid 1,1-dioxide
EP0069962B1 (en) * 1981-07-15 1985-01-02 Kanebo, Ltd. Novel ester of 1,1-dioxopenicillanic acid, process for production thereof, and use thereof as beta-lactamase inhibitor
PT76526B (en) * 1982-04-19 1986-01-21 Gist Brocades Nv Preparation of 6-alpha-bromo- and/or 6,6-dibromopenicillanic acid 1,1-dioxides
US4502988A (en) * 1983-08-08 1985-03-05 Eli Lilly And Company Oxidation process
EP0139047A1 (en) * 1983-10-18 1985-05-02 Gist-Brocades N.V. Process for the preparation of 6,6-dibromopenicillanic acid 1,1-dioxide
US4647457A (en) * 1983-12-16 1987-03-03 Hoffmann-La Roche Inc. Penicillanic acid derivatives
WO1987006230A1 (en) * 1986-04-10 1987-10-22 Leo Pharmaceutical Products Ltd. A/S Method for preparing penicillanic acid derivatives
GB8808701D0 (en) * 1988-04-13 1988-05-18 Erba Carlo Spa Beta-lactam derivatives
CN102977120B (zh) * 2012-12-14 2015-05-27 江西富祥药业股份有限公司 一种舒巴坦匹酯制备及结晶方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3197466A (en) * 1961-10-30 1965-07-27 Smith Kline French Lab Penicillin sulfoxides and process
LU77306A1 (US07968547-20110628-C00004.png) * 1977-05-09 1979-01-18
JPS5439090A (en) * 1977-07-13 1979-03-24 Glaxo Group Ltd Betaalactam compound and its preparation

Also Published As

Publication number Publication date
FR2393804A1 (fr) 1979-01-05
SE7806628L (sv) 1978-12-08
NO151746B (no) 1985-02-18
IL62168A0 (en) 1981-03-31
YU41829B (en) 1988-02-29
FI66003B (fi) 1984-04-30
CH634073A5 (en) 1983-01-14
NZ187476A (en) 1982-08-17
GB2000138A (en) 1979-01-04
DE2857263B2 (de) 1981-04-23
FI781800A (fi) 1978-12-08
GR72255B (US07968547-20110628-C00004.png) 1983-10-06
SE8305916L (sv) 1983-10-27
NO152448C (no) 1985-10-02
GB2000138B (en) 1982-03-03
YU117078A (en) 1983-01-21
DK155740B (da) 1989-05-08
IE781140L (en) 1978-12-07
FR2393805A1 (fr) 1979-01-05
NL7806126A (nl) 1978-12-11
DK251478A (da) 1978-12-08
PT68146A (en) 1978-07-01
NO781970L (no) 1978-12-08
SG65383G (en) 1985-03-29
ATA411278A (de) 1980-06-15
NL930064I2 (nl) 1994-04-18
LU79774A1 (fr) 1980-01-22
DK155740C (da) 1989-10-23
IN149747B (US07968547-20110628-C00004.png) 1982-04-03
PL114501B1 (en) 1981-02-28
PL207396A1 (pl) 1979-06-04
SU860706A1 (ru) 1981-08-30
NL180009C (nl) 1986-12-16
PH21116A (en) 1987-07-16
DE2824535C3 (de) 1981-01-22
AU513636B2 (en) 1980-12-11
HU180042B (en) 1983-01-28
EG13869A (en) 1983-03-31
FR2393805B1 (US07968547-20110628-C00004.png) 1984-02-24
SE447995B (sv) 1987-01-12
FR2393804B1 (US07968547-20110628-C00004.png) 1980-11-07
IE47079B1 (en) 1983-12-14
ATA128580A (de) 1981-02-15
KE3355A (en) 1983-12-16
IT1096381B (it) 1985-08-26
IL54867A0 (en) 1978-08-31
PH16465A (en) 1983-10-20
AT364084B (de) 1981-09-25
NO823126L (no) 1978-12-08
NO151746C (no) 1985-06-05
OA05964A (fr) 1981-06-30
DE2824535A1 (de) 1978-12-14
IL54867A (en) 1981-11-30
AT360649B (de) 1981-01-26
DE2857263C3 (de) 1981-12-17
MY8500092A (en) 1985-12-31
AU3683878A (en) 1979-12-06
DD140888A5 (de) 1980-04-02
NO152448B (no) 1985-06-24
HK13184A (en) 1984-02-24
DE2824535B2 (de) 1980-05-14
BG34614A3 (en) 1983-10-15
SE8305916D0 (sv) 1983-10-27
DD148585A5 (de) 1981-06-03
BG34615A3 (en) 1983-10-15
BE867859A (fr) 1978-12-06
NL930064I1 (nl) 1993-09-01
FI66003C (fi) 1984-08-10
AR224111A1 (es) 1981-10-30
CS208472B2 (en) 1981-09-15
IT7824270A0 (it) 1978-06-06
PH26810A (en) 1992-11-05

Similar Documents

Publication Publication Date Title
SE436206B (sv) Penicillansyra-1,1-dioxider med antibakteriell verkan
US4234579A (en) Penicillanic acid 1,1-dioxides as β-lactamase inhibitors
US4276285A (en) Combinations of penicillanic acid 1,1-dioxide with 7-(D-2-[4-ethylpiperazin-2,3-dione-1-carboxamido]-2-[4-hydroxyphenyl]acetamido)-3-([1-methyl-5-tetrazolyl]thiomethyl)-3-desacetoxymethylcephalosporanic acid
US4342768A (en) Bis-esters of 1,1-alkanediols with 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide and beta-lactam antibiotics
US4256733A (en) Acetoxymethyl penam compounds as β-lactamase inhibitors
US4377590A (en) Derivatives of ampicillin and amoxicillin with beta-lactamase inhibitors
EP0008917B1 (en) Penam-3-carboxylic acid 1,1-dioxides, process for their preparation and pharmaceutical compositions
US4420426A (en) 6-Alpha-halopenicillanic acid 1,1-dioxides
US4260598A (en) Method for increasing antibacterial effectiveness of a β-lactam antibiotic
HU186304B (en) Process for producing pename-sulfoxide-derivatives
US4576939A (en) Penem derivatives
US4762920A (en) 6,6-Dihalopenicillanic acid 1,1-dioxides
HU189211B (en) Process for preparing 1,1-dioxides of 6-amnioalkyl-penam-3-carboxylic acid and derivatives thereof applied as beta-lactamase inhibitors
US4714761A (en) 6,6-dihalopenicillanic acid 1,1-dioxides and process
JPS6145993B2 (US07968547-20110628-C00004.png)
CA1270814A (en) 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives
EP0002927B1 (en) Penicillanic acid derivatives, processes for their preparation and pharmaceutical compositions containing them
KR820000740B1 (ko) 페니실란산 1, 1-디옥사이드의 제조방법
CA1119164A (en) PENICILLANIC ACID 1,1-DIOXIDES AS .beta.-LACTAMASE INHIBITORS
KR810002025B1 (ko) 페니실란산 1, 1-디옥사이드의 제조방법
NZ199608A (en) Administering penicillanic acid 1,1-dioxides with beta-lactam antibiotics
NZ199601A (en) Coadministration of a cephalosporin derivative and a penicillin
JPH02191284A (ja) 抗菌用組成物

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 7806628-9

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 7806628-9

Format of ref document f/p: F