SE0201635D0 - Novel compounds - Google Patents
Novel compoundsInfo
- Publication number
- SE0201635D0 SE0201635D0 SE0201635A SE0201635A SE0201635D0 SE 0201635 D0 SE0201635 D0 SE 0201635D0 SE 0201635 A SE0201635 A SE 0201635A SE 0201635 A SE0201635 A SE 0201635A SE 0201635 D0 SE0201635 D0 SE 0201635D0
- Authority
- SE
- Sweden
- Prior art keywords
- novel compounds
- useful
- formula
- relates
- present
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 150000002475 indoles Chemical class 0.000 abstract 1
- 208000023504 respiratory system disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (25)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0201635A SE0201635D0 (sv) | 2002-05-30 | 2002-05-30 | Novel compounds |
| TW092114174A TW200407305A (en) | 2002-05-30 | 2003-05-26 | Novel compounds |
| ES03725970T ES2360936T3 (es) | 2002-05-30 | 2003-05-27 | Indoles sustituidos. |
| AU2003228201A AU2003228201A1 (en) | 2002-05-30 | 2003-05-27 | Novel substituted indoles |
| KR10-2004-7019452A KR20050010507A (ko) | 2002-05-30 | 2003-05-27 | 신규 치환 인돌 |
| AT03725970T ATE501118T1 (de) | 2002-05-30 | 2003-05-27 | Substituierte indole |
| CA002487675A CA2487675A1 (en) | 2002-05-30 | 2003-05-27 | Novel substituted indoles |
| UA20041109794A UA79464C2 (en) | 2002-05-30 | 2003-05-27 | Substituted indoles, methods for their production and method for treating disorders mediated by prostaglandin d2 |
| US10/516,557 US7166607B2 (en) | 2002-05-30 | 2003-05-27 | Substituted indoles |
| DE60336314T DE60336314D1 (de) | 2002-05-30 | 2003-05-27 | Substituierte indole |
| EP03725970A EP1513812B1 (en) | 2002-05-30 | 2003-05-27 | Substituted indoles |
| PL03375111A PL375111A1 (en) | 2002-05-30 | 2003-05-27 | Novel substituted indoles |
| PCT/SE2003/000856 WO2003101961A1 (en) | 2002-05-30 | 2003-05-27 | Novel substituted indoles |
| CNB038183447A CN100404505C (zh) | 2002-05-30 | 2003-05-27 | 新的取代吲哚 |
| MXPA04011876A MXPA04011876A (es) | 2002-05-30 | 2003-05-27 | Nuevos indoles sustituidos. |
| JP2004509654A JP4485354B2 (ja) | 2002-05-30 | 2003-05-27 | 新規な置換インドール類 |
| BR0311494-5A BR0311494A (pt) | 2002-05-30 | 2003-05-27 | Novos indóis substituìdos |
| NZ536883A NZ536883A (en) | 2002-05-30 | 2003-05-27 | Novel substituted indoles |
| RU2004135064/04A RU2288914C2 (ru) | 2002-05-30 | 2003-05-27 | Новые замещенные индолы |
| MYPI20031973A MY133624A (en) | 2002-05-30 | 2003-05-28 | Thio-substituted indole acetic acid derivatives for the treatment of respiratory disease |
| ARP030101932A AR039934A1 (es) | 2002-05-30 | 2003-05-30 | Indoles sustituidos para el tratamiento de desordenes respiratorios |
| CO04120052A CO5631431A2 (es) | 2002-05-30 | 2004-11-29 | Indoles sustituidos novedosos |
| ZA200409641A ZA200409641B (en) | 2002-05-30 | 2004-11-29 | Novel substituted indoles. |
| IS7607A IS7607A (is) | 2002-05-30 | 2004-12-21 | Ný útskipt indól |
| NO20045589A NO20045589L (no) | 2002-05-30 | 2004-12-22 | Nye forbindelser |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0201635A SE0201635D0 (sv) | 2002-05-30 | 2002-05-30 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE0201635D0 true SE0201635D0 (sv) | 2002-05-30 |
Family
ID=20288018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE0201635A SE0201635D0 (sv) | 2002-05-30 | 2002-05-30 | Novel compounds |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7166607B2 (https=) |
| EP (1) | EP1513812B1 (https=) |
| JP (1) | JP4485354B2 (https=) |
| KR (1) | KR20050010507A (https=) |
| CN (1) | CN100404505C (https=) |
| AR (1) | AR039934A1 (https=) |
| AT (1) | ATE501118T1 (https=) |
| AU (1) | AU2003228201A1 (https=) |
| BR (1) | BR0311494A (https=) |
| CA (1) | CA2487675A1 (https=) |
| CO (1) | CO5631431A2 (https=) |
| DE (1) | DE60336314D1 (https=) |
| ES (1) | ES2360936T3 (https=) |
| IS (1) | IS7607A (https=) |
| MX (1) | MXPA04011876A (https=) |
| MY (1) | MY133624A (https=) |
| NO (1) | NO20045589L (https=) |
| NZ (1) | NZ536883A (https=) |
| PL (1) | PL375111A1 (https=) |
| RU (1) | RU2288914C2 (https=) |
| SE (1) | SE0201635D0 (https=) |
| TW (1) | TW200407305A (https=) |
| UA (1) | UA79464C2 (https=) |
| WO (1) | WO2003101961A1 (https=) |
| ZA (1) | ZA200409641B (https=) |
Families Citing this family (102)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200307542A (en) | 2002-05-30 | 2003-12-16 | Astrazeneca Ab | Novel compounds |
| SE0201635D0 (sv) | 2002-05-30 | 2002-05-30 | Astrazeneca Ab | Novel compounds |
| SE0202241D0 (sv) * | 2002-07-17 | 2002-07-17 | Astrazeneca Ab | Novel Compounds |
| ZA200505523B (en) | 2002-12-20 | 2006-09-27 | Amgen Inc | Asthma and allergic inflammation modulators |
| SE0301010D0 (sv) | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SE0301569D0 (sv) * | 2003-05-27 | 2003-05-27 | Astrazeneca Ab | Novel compounds |
| SE0302232D0 (sv) * | 2003-08-18 | 2003-08-18 | Astrazeneca Ab | Novel Compounds |
| SA04250253B1 (ar) | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
| AU2004283139A1 (en) * | 2003-10-14 | 2005-05-06 | Oxagen Limited | Compounds having CRTH2 antagonist activity |
| GB0324763D0 (en) | 2003-10-23 | 2003-11-26 | Oxagen Ltd | Use of compounds in therapy |
| SE0303180D0 (sv) * | 2003-11-26 | 2003-11-26 | Astrazeneca Ab | Novel compounds |
| AU2005229356B2 (en) | 2004-03-11 | 2011-06-09 | Idorsia Pharmaceuticals Ltd | Tetrahydropyridoindole derivatives |
| US7417063B2 (en) | 2004-04-13 | 2008-08-26 | Bristol-Myers Squibb Company | Bicyclic heterocycles useful as serine protease inhibitors |
| BRPI0511676A (pt) | 2004-05-29 | 2008-01-08 | 7Tm Pharma As | uso medicinal de ligandos receptores |
| GB0412914D0 (en) * | 2004-06-10 | 2004-07-14 | Oxagen Ltd | Compounds |
| MY144903A (en) * | 2004-06-17 | 2011-11-30 | Novartis Ag | Pyrrolopyridine derivatives and their use as crth2 antagonists |
| GB0415320D0 (en) | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
| GB0418830D0 (en) | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
| JP5063348B2 (ja) * | 2004-08-26 | 2012-10-31 | アクテリオン ファーマシューティカルズ リミテッド | ２−スルファニル−ベンゾイミダゾール−１−イル−酢酸誘導体 |
| MX2007003336A (es) | 2004-09-21 | 2007-06-05 | Athersys Inc | Acidos aceticos de indol que muestran antagonismo de receptor crth2 y usos de los mismos. |
| EP1809602B1 (en) * | 2004-10-27 | 2008-10-29 | Janssen Pharmaceutica N.V. | Indole derivatives useful as progesterone receptor modulators |
| JP5208510B2 (ja) | 2004-11-23 | 2013-06-12 | アストラゼネカ・アクチエボラーグ | 呼吸器疾患の処置に有用なフェノキシ酢酸誘導体 |
| ES2369782T3 (es) | 2004-12-27 | 2011-12-05 | Actelion Pharmaceuticals Ltd. | Derivados de 2,3,4,9-tetrahidro-1h-carbazol como antagonistas del receptor crth2. |
| GB0500604D0 (en) * | 2005-01-13 | 2005-02-16 | Astrazeneca Ab | Novel process |
| EP2397476A3 (en) | 2005-07-22 | 2011-12-28 | Shionogi & Co., Ltd. | Indole derivative having PGD2 receptor antagonist activity |
| JP5064219B2 (ja) | 2005-07-22 | 2012-10-31 | 塩野義製薬株式会社 | Ｐｇｄ２受容体アンタゴニスト活性を有するアザインドール酸誘導体 |
| US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
| TW200745003A (en) | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
| US8148572B2 (en) | 2005-10-06 | 2012-04-03 | Astrazeneca Ab | Compounds |
| GB0521275D0 (en) * | 2005-10-19 | 2005-11-30 | Argenta Discovery Ltd | 3-Aminoindole compounds |
| GB0524428D0 (en) | 2005-11-30 | 2006-01-11 | 7Tm Pharma As | Medicinal use of receptor ligands |
| GB0525143D0 (en) * | 2005-12-09 | 2006-01-18 | Novartis Ag | Organic compounds |
| CN101454284A (zh) * | 2006-05-26 | 2009-06-10 | 阿斯利康(瑞典)有限公司 | 联芳基或芳基-杂芳基取代的吲哚类化合物 |
| EP2037967B1 (en) | 2006-06-16 | 2016-12-07 | The Trustees Of The University Of Pennsylvania | Prostaglandin d2 receptor antagonists for treating androgenetic alopecia |
| US7999119B2 (en) | 2006-07-22 | 2011-08-16 | Oxagen Limited | Compounds having CRTH2 antagonist activity |
| BRPI0715179A2 (pt) | 2006-08-07 | 2013-06-11 | Actelion Pharmaceuticals Ltd | composto, composiÇço farmacÊutica e uso de um composto |
| US20100137300A1 (en) * | 2007-03-21 | 2010-06-03 | George Hynd | Indolizine Acetic Acid Derivatives as CRTH2 Antagonists |
| UA100983C2 (ru) | 2007-07-05 | 2013-02-25 | Астразенека Аб | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты |
| PT2229358E (pt) | 2007-12-14 | 2011-06-29 | Pulmagen Therapeutics Asthma Ltd | Indoles e sua utilização terapêutica |
| ES2471919T3 (es) | 2007-12-19 | 2014-06-27 | Amgen, Inc | Derivados de ácido fenilac�tico como moduladores de inflamación |
| US7750027B2 (en) * | 2008-01-18 | 2010-07-06 | Oxagen Limited | Compounds having CRTH2 antagonist activity |
| AU2009204700B2 (en) | 2008-01-18 | 2013-07-04 | Atopix Therapeutics Limited | Compounds having CRTH2 antagonist activity |
| EP2265581A1 (en) | 2008-01-22 | 2010-12-29 | Oxagen Limited | Compounds having crth2 antagonist activity |
| JP2011509991A (ja) | 2008-01-22 | 2011-03-31 | オキサジェン リミテッド | Ｃｒｔｈ２アンタゴニスト活性を有する化合物 |
| WO2011055270A1 (en) | 2009-11-04 | 2011-05-12 | Wyeth Llc | Indole based receptor crth2 antagonists |
| SG181900A1 (en) | 2009-12-23 | 2012-08-30 | Ironwood Pharmaceuticals Inc | Crth2 modulators |
| US20130178475A1 (en) | 2010-03-17 | 2013-07-11 | Ironwood Pharmaceuticals, Inc. | sGC STIMULATORS |
| PT2558447E (pt) | 2010-03-22 | 2014-11-25 | Actelion Pharmaceuticals Ltd | Derivados de 3-(heteroarilamino)-1,2,3,4-tetrahidro-9hcarbazol e o seu uso como moduladores do receptor de prostaglandina d2 |
| AR088020A1 (es) | 2010-06-30 | 2014-05-07 | Ironwood Pharmaceuticals Inc | Compuestos heterociclicos como estimuladores de sgc |
| US20130216552A1 (en) | 2010-07-12 | 2013-08-22 | Ironwood Pharmaceuticals, Inc. | Crth2 modulators |
| WO2012009134A1 (en) | 2010-07-12 | 2012-01-19 | Ironwood Pharmaceuticals, Inc. | Crth2 modulators |
| EP2637659B1 (en) | 2010-11-09 | 2016-05-18 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| DK2697223T3 (en) | 2011-04-14 | 2016-09-05 | Actelion Pharmaceuticals Ltd | 7- (heteroaryl-amino) -6,7,8,9-tetrahydro-pyrido [1,2-a] indole-acetic acid derivatives and their use as prostaglandin D2 receptor |
| EP2710119A4 (en) * | 2011-05-17 | 2015-02-18 | Cleave Biosciences Inc | COMPOSITIONS AND METHODS FOR JAMM PROTEIN INHIBITION |
| EP2790696A1 (en) | 2011-12-16 | 2014-10-22 | Atopix Therapeutics Limited | Combination of crth2 antagonist and a proton pump inhibitor for the treatment of eosinophilic esophagitis |
| WO2013096744A1 (en) | 2011-12-21 | 2013-06-27 | Novira Therapeutics, Inc. | Hepatitis b antiviral agents |
| CN106117194A (zh) | 2011-12-27 | 2016-11-16 | 铁木医药有限公司 | 可用作sgc刺激剂的2‑苄基、3‑(嘧啶‑2‑基)取代的吡唑类 |
| CA2867901A1 (en) | 2012-03-21 | 2013-09-26 | The Trustees Of The University Of Pennsylvania | Compositions and methods for regulating hair growth |
| EA038942B1 (ru) | 2012-08-28 | 2021-11-12 | Янссен Сайенсиз Айрлэнд Юси | Сульфамоил-ариламиды и их применение в качестве лекарственных препаратов для лечения гепатита b |
| EA026957B1 (ru) * | 2012-08-28 | 2017-06-30 | Янссен Сайенсиз Айрлэнд Юси | Конденсированные бициклические производные сульфамоила и их применение в качестве лекарственных препаратов для лечения гепатита b |
| US9309235B2 (en) | 2012-09-18 | 2016-04-12 | Ironwood Pharmaceuticals, Inc. | SGC stimulators |
| US9487508B2 (en) | 2012-09-19 | 2016-11-08 | Ironwood Pharmaceuticals, Inc. | SGC stimulators |
| HUE034820T2 (en) | 2013-02-28 | 2018-02-28 | Janssen Sciences Ireland Uc | Sulphamoyl arylamides and their use as medicaments for the treatment of hepatitis B |
| SI2970243T1 (sl) | 2013-03-15 | 2020-04-30 | Cyclerion Therapeutics, Inc. | SGC stimulatorji |
| EA027068B1 (ru) | 2013-04-03 | 2017-06-30 | Янссен Сайенсиз Айрлэнд Юси | Производные n-фенилкарбоксамида и их применение в качестве лекарственных препаратов для лечения гепатита b |
| TWI651300B (zh) | 2013-05-17 | 2019-02-21 | 健生科學愛爾蘭無限公司 | 胺磺醯基吡咯醯胺衍生物及其作為用於治療ｂ型肝炎藥物的用途 |
| DK3024819T3 (en) | 2013-07-25 | 2018-06-06 | Janssen Sciences Ireland Uc | GLYOXAMIDE-SUBSTITUTED PYRROLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICINES FOR TREATING HEPATITIS B |
| KR102290189B1 (ko) | 2013-10-23 | 2021-08-17 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | 카르복스아미드 유도체 및 ｂ형 간염 치료용 의약으로서의 이의 용도 |
| JP2016540017A (ja) | 2013-12-11 | 2016-12-22 | アイアンウッド ファーマシューティカルズ インコーポレイテッド | ｓＧＣ刺激物質 |
| GB201322273D0 (en) | 2013-12-17 | 2014-01-29 | Atopix Therapeutics Ltd | Process |
| WO2015106268A1 (en) | 2014-01-13 | 2015-07-16 | Ironwood Pharmaceuticals, Inc. | USE OF sGC STIMULATORS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS |
| US10392349B2 (en) | 2014-01-16 | 2019-08-27 | Novira Therapeutics, Inc. | Azepane derivatives and methods of treating hepatitis B infections |
| US9169212B2 (en) | 2014-01-16 | 2015-10-27 | Novira Therapeutics, Inc. | Azepane derivatives and methods of treating hepatitis B infections |
| JP6553059B2 (ja) | 2014-02-05 | 2019-07-31 | ノヴィラ・セラピューティクス・インコーポレイテッド | Ｈｂｖ感染の治療のための併用療法 |
| WO2015118057A1 (en) | 2014-02-06 | 2015-08-13 | Janssen Sciences Ireland Uc | Sulphamoylpyrrolamide derivatives and the use thereof as medicaments for the treatment of hepatitis b |
| AR099767A1 (es) | 2014-03-17 | 2016-08-17 | Actelion Pharmaceuticals Ltd | Derivados del ácido acético azaindol y su uso como moduladores del receptor de prostaglandina d2 |
| KR20160133536A (ko) | 2014-03-18 | 2016-11-22 | 액테리온 파마슈티칼 리미티드 | 아자인돌 아세트산 유도체 및 프로스타글란딘 d2 수용체 조절제로서의 이의 용도 |
| GB201407820D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
| GB201407807D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
| TWI695831B (zh) * | 2014-09-13 | 2020-06-11 | 香港商南北兄弟藥業投資有限公司 | Ｃｒｔｈ２拮抗劑化合物及其用途 |
| US20170298055A1 (en) | 2014-09-17 | 2017-10-19 | Ironwood Pharmaceuticals, Inc. | sGC STIMULATORS |
| US20170291889A1 (en) | 2014-09-17 | 2017-10-12 | Ironwood Pharmaceuticals, Inc. | Pyrazole derivatives as sgc stimulators |
| EP3194386A2 (en) | 2014-09-17 | 2017-07-26 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| ES2991300T3 (es) | 2015-02-13 | 2024-12-03 | Inserm Institut Nat De La Sante Et De Larecherche Medicale | Antagonistas de PTGDR-1 y/o PTGDR-2 para prevenir y/o tratar lupus eritematoso sistémico |
| EP3271019A1 (en) | 2015-03-19 | 2018-01-24 | Novira Therapeutics Inc. | Azocane and azonane derivatives and methods of treating hepatitis b infections |
| US10875876B2 (en) | 2015-07-02 | 2020-12-29 | Janssen Sciences Ireland Uc | Cyclized sulfamoylarylamide derivatives and the use thereof as medicaments for the treatment of hepatitis B |
| ES2947824T3 (es) | 2015-07-30 | 2023-08-21 | Univ Pennsylvania | Alelos polimórficos de un solo nucleótido del gen DP-2 humano para la detección de la susceptibilidad a la inhibición del crecimiento del cabello por antagonistas de PGD2 |
| AU2016323262B2 (en) | 2015-09-15 | 2020-11-19 | Idorsia Pharmaceuticals Ltd | Crystalline forms |
| HK1259410A1 (zh) | 2015-09-29 | 2019-11-29 | 诺维拉治疗公司 | 乙型肝炎抗病毒剂的晶体形式 |
| SG10202011827YA (en) | 2016-04-15 | 2021-01-28 | Novira Therapeutics Inc | Combinations and methods comprising a capsid assembly inhibitor |
| MX389964B (es) | 2016-07-07 | 2025-03-19 | Cyclerion Therapeutics Inc | Formas sólidas de un estimulador de guanilato ciclasa soluble (sgc). |
| CN109476686B (zh) | 2016-07-07 | 2022-01-18 | 赛克里翁治疗有限公司 | sGC刺激剂的磷前药 |
| CA3090125A1 (en) | 2018-03-14 | 2019-09-19 | Janssen Sciences Ireland Unlimited Company | Capsid assembly modulator dosing regimen |
| MX2021010145A (es) | 2019-02-22 | 2021-09-14 | Janssen Sciences Ireland Unlimited Co | Derivados de amida utiles en el tratamiento de una infeccion por vhb o de enfermedades inducidas por vhb. |
| MA55879A (fr) | 2019-05-06 | 2022-03-16 | Janssen Sciences Ireland Unlimited Co | Dérivés d'amide utiles dans le traitement d'une infection par le virus de l'hépatite b ou de maladies induites par le virus de l'hépatite b |
| JP2023515918A (ja) | 2020-01-13 | 2023-04-17 | デュレクト コーポレーション | 不純物が低減された徐放性薬物送達システム及び関連の方法 |
| CA3203561A1 (en) | 2021-01-12 | 2022-07-21 | Adrian Neil Verity | Sustained release drug delivery systems and related methods |
| CN114835678A (zh) * | 2021-02-02 | 2022-08-02 | 广东东阳光药业有限公司 | 吲哚衍生物的盐及其用途 |
| CN114835677B (zh) * | 2021-02-02 | 2025-09-26 | 广东东阳光药业股份有限公司 | 吲哚衍生物的盐及其用途 |
| CN114989136A (zh) * | 2021-02-02 | 2022-09-02 | 广东东阳光药业有限公司 | 吲哚衍生物的盐及其用途 |
| CN115093360B (zh) * | 2022-07-06 | 2023-11-17 | 都创(上海)医药科技股份有限公司 | 一种吲哚类衍生物的合成方法 |
| CN117205206A (zh) * | 2023-08-16 | 2023-12-12 | 江南大学 | 一种能改善哮喘小鼠病理特征的色氨酸代谢物及其应用 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE790679A (fr) * | 1971-11-03 | 1973-04-27 | Ici Ltd | Derives de l'indole |
| JPS5239671A (en) * | 1975-09-22 | 1977-03-28 | Sankyo Co Ltd | Process for preparing indole-3-thioether compounds |
| US5095031A (en) | 1990-08-20 | 1992-03-10 | Abbott Laboratories | Indole derivatives which inhibit leukotriene biosynthesis |
| WO1993005020A1 (en) | 1991-09-06 | 1993-03-18 | Merck & Co., Inc. | Indoles as inhibitors of hiv reverse transcriptase |
| FR2692574B1 (fr) | 1992-06-23 | 1995-06-23 | Sanofi Elf | Derives hydroxy-4 benzenethio, leur preparation ainsi que leur utilisation pour la preparation de derives aminoalkoxybenzenesulfonyles. |
| AU6165894A (en) | 1993-01-28 | 1994-08-15 | Trustees Of The University Of Pennsylvania, The | Use of creatine or analogs for the manufacture of a medicament for inhibiting tumor growth |
| HUT74614A (en) | 1993-02-24 | 1997-01-28 | Merck & Co Inc | Nindol derivates suitable for treatment of infection by hiv and pharmaceutical compositions containing them |
| US5486525A (en) * | 1993-12-16 | 1996-01-23 | Abbott Laboratories | Platelet activating factor antagonists: imidazopyridine indoles |
| US5567711A (en) | 1995-04-19 | 1996-10-22 | Abbott Laboratories | Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists |
| TW472045B (en) | 1996-09-25 | 2002-01-11 | Astra Ab | Protein kinase C inhibitor compounds, method for their preparation, pharmaceutical composition thereof and intermediate used for their preparation |
| AR017256A1 (es) | 1997-08-21 | 2001-09-05 | American Home Prod | Compuestos de indol sustituidos, metodo para la sintesis en fase solida de los mismos, conjuntos de combinacion para ser empleados en dicho metodo, uso delos compuestos para preparar un medicamento y composiciones farmaceuticas que los comprenden |
| DE69814012T2 (de) | 1997-12-19 | 2004-04-01 | Eli Lilly And Co., Indianapolis | Hypoglykàmische imidazoline derivate |
| AU5886500A (en) | 1999-06-23 | 2001-01-09 | Sepracor, Inc. | Indolyl-benzimidazole antibacterials, and methods of use thereof |
| AU7962200A (en) | 1999-10-29 | 2001-05-14 | Wakunaga Pharmaceutical Co., Ltd | Novel indole derivatives and drugs containing the same as the active ingredient |
| OA12514A (en) | 1999-12-24 | 2006-05-29 | Aventis Pharma Ltd | Azaindoles. |
| NZ522074A (en) | 2000-05-31 | 2004-06-25 | Astrazeneca Ab | Indole derivatives with vascular damaging activity |
| US6878522B2 (en) | 2000-07-07 | 2005-04-12 | Baiyong Li | Methods for the identification of compounds useful for the treatment of disease states mediated by prostaglandin D2 |
| CA2473803A1 (en) | 2002-02-01 | 2003-08-07 | Robert Greenhouse | Substituted indoles as alpha-1 agonists |
| EP2423190A1 (en) | 2002-05-16 | 2012-02-29 | Shionogi&Co., Ltd. | Compounds Exhibiting PGD 2 Receptor Antagonism |
| SE0201635D0 (sv) | 2002-05-30 | 2002-05-30 | Astrazeneca Ab | Novel compounds |
| TW200307542A (en) | 2002-05-30 | 2003-12-16 | Astrazeneca Ab | Novel compounds |
| SE0202241D0 (sv) | 2002-07-17 | 2002-07-17 | Astrazeneca Ab | Novel Compounds |
| SE0301569D0 (sv) | 2003-05-27 | 2003-05-27 | Astrazeneca Ab | Novel compounds |
| SE0302232D0 (sv) | 2003-08-18 | 2003-08-18 | Astrazeneca Ab | Novel Compounds |
| SE0303180D0 (sv) | 2003-11-26 | 2003-11-26 | Astrazeneca Ab | Novel compounds |
-
2002
- 2002-05-30 SE SE0201635A patent/SE0201635D0/xx unknown
-
2003
- 2003-05-26 TW TW092114174A patent/TW200407305A/zh unknown
- 2003-05-27 WO PCT/SE2003/000856 patent/WO2003101961A1/en not_active Ceased
- 2003-05-27 BR BR0311494-5A patent/BR0311494A/pt not_active IP Right Cessation
- 2003-05-27 ES ES03725970T patent/ES2360936T3/es not_active Expired - Lifetime
- 2003-05-27 AU AU2003228201A patent/AU2003228201A1/en not_active Abandoned
- 2003-05-27 KR KR10-2004-7019452A patent/KR20050010507A/ko not_active Ceased
- 2003-05-27 NZ NZ536883A patent/NZ536883A/en unknown
- 2003-05-27 EP EP03725970A patent/EP1513812B1/en not_active Expired - Lifetime
- 2003-05-27 UA UA20041109794A patent/UA79464C2/uk unknown
- 2003-05-27 CN CNB038183447A patent/CN100404505C/zh not_active Expired - Fee Related
- 2003-05-27 CA CA002487675A patent/CA2487675A1/en not_active Abandoned
- 2003-05-27 US US10/516,557 patent/US7166607B2/en not_active Expired - Fee Related
- 2003-05-27 MX MXPA04011876A patent/MXPA04011876A/es active IP Right Grant
- 2003-05-27 JP JP2004509654A patent/JP4485354B2/ja not_active Expired - Fee Related
- 2003-05-27 DE DE60336314T patent/DE60336314D1/de not_active Expired - Lifetime
- 2003-05-27 RU RU2004135064/04A patent/RU2288914C2/ru not_active IP Right Cessation
- 2003-05-27 PL PL03375111A patent/PL375111A1/xx not_active Application Discontinuation
- 2003-05-27 AT AT03725970T patent/ATE501118T1/de not_active IP Right Cessation
- 2003-05-28 MY MYPI20031973A patent/MY133624A/en unknown
- 2003-05-30 AR ARP030101932A patent/AR039934A1/es not_active Application Discontinuation
-
2004
- 2004-11-29 CO CO04120052A patent/CO5631431A2/es not_active Application Discontinuation
- 2004-11-29 ZA ZA200409641A patent/ZA200409641B/xx unknown
- 2004-12-21 IS IS7607A patent/IS7607A/is unknown
- 2004-12-22 NO NO20045589A patent/NO20045589L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20050165055A1 (en) | 2005-07-28 |
| CN1671659A (zh) | 2005-09-21 |
| AR039934A1 (es) | 2005-03-09 |
| TW200407305A (en) | 2004-05-16 |
| CA2487675A1 (en) | 2003-12-11 |
| CN100404505C (zh) | 2008-07-23 |
| KR20050010507A (ko) | 2005-01-27 |
| PL375111A1 (en) | 2005-11-28 |
| IS7607A (is) | 2004-12-21 |
| AU2003228201A1 (en) | 2003-12-19 |
| MY133624A (en) | 2007-11-30 |
| NZ536883A (en) | 2006-08-31 |
| RU2004135064A (ru) | 2005-08-10 |
| US7166607B2 (en) | 2007-01-23 |
| NO20045589L (no) | 2005-02-02 |
| ES2360936T3 (es) | 2011-06-10 |
| BR0311494A (pt) | 2005-03-29 |
| WO2003101961A1 (en) | 2003-12-11 |
| EP1513812A1 (en) | 2005-03-16 |
| ZA200409641B (en) | 2006-02-22 |
| UA79464C2 (en) | 2007-06-25 |
| ATE501118T1 (de) | 2011-03-15 |
| EP1513812B1 (en) | 2011-03-09 |
| CO5631431A2 (es) | 2006-04-28 |
| JP4485354B2 (ja) | 2010-06-23 |
| MXPA04011876A (es) | 2005-03-31 |
| RU2288914C2 (ru) | 2006-12-10 |
| JP2005538955A (ja) | 2005-12-22 |
| DE60336314D1 (de) | 2011-04-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SE0201635D0 (sv) | Novel compounds | |
| SE0303180D0 (sv) | Novel compounds | |
| SE0302232D0 (sv) | Novel Compounds | |
| SE0202241D0 (sv) | Novel Compounds | |
| TW200510301A (en) | Novel compounds | |
| BRPI0408369A (pt) | derivados de indol úteis para o tratamento de doenças | |
| EA200870127A1 (ru) | Полициклические производные аминокислот и способы их применения | |
| DE60229530D1 (de) | Substituierte piperazine als modulatoren des melanocortinrezeptors | |
| TW200503724A (en) | Novel pharmaceuticals | |
| MXPA03011484A (es) | Heteroarilos multiciclicos sustituidos con quinuclidinas para el tratamiento de enfermedades. | |
| ATE307810T1 (de) | Imidazol-2-carbonsäureamid derivate als raf- kinase-inhibitoren | |
| EA200601141A1 (ru) | Сульфонамидные производные для лечения заболеваний | |
| MXPA04004301A (es) | Bencimidazoles sustituidos utiles como inhibidores de la proteina cinasa. | |
| NO20063275L (no) | Anvendelse av substituerte 2-aminotetraliner for forebyggende behandling av Parkinsons sykdom | |
| DE60214990D1 (de) | Benzolsulfonsäureester-indol-5-yl als 5-ht6 rezeptor-antagonisten | |
| EA200801608A1 (ru) | Производные бензимидазолонкарбоновой кислоты | |
| CY1109569T1 (el) | Υποκατεστημενα παραγωγα κυκλοεξανο-1,4-διαμινης | |
| TW200720260A (en) | Prokineticin 1 receptor antagonists | |
| MX2007011847A (es) | Derivados de pirimidindiona como antagonistas del receptor de procineticina 2. | |
| EA200601462A1 (ru) | Соединения для лечения заболеваний | |
| TW200728258A (en) | Novel compounds | |
| BR0318521A (pt) | arilindenopiridinas e arilindenopirimidinas e métodos terapêuticos e profiláticos relacionados | |
| DK1648904T3 (da) | N-sulfonylheterocyclopyrrolalkylaminforbindelser som 5-hydroxytryptamin-6-ligander | |
| NO20074622L (no) | Metabolitter for NK-1 antagonister for brekninger | |
| NO20050270L (no) | Nye forbindelser, deres anvendelse og fremstilling |