RU99109690A - Нарингин и нарингенин в качестве ингибитора 3-гидрокси-3-метилглутарил коа (hmg-coа) редуктазы - Google Patents

Нарингин и нарингенин в качестве ингибитора 3-гидрокси-3-метилглутарил коа (hmg-coа) редуктазы

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Publication number
RU99109690A
RU99109690A RU99109690/14A RU99109690A RU99109690A RU 99109690 A RU99109690 A RU 99109690A RU 99109690/14 A RU99109690/14 A RU 99109690/14A RU 99109690 A RU99109690 A RU 99109690A RU 99109690 A RU99109690 A RU 99109690A
Authority
RU
Russia
Prior art keywords
coa
naringin
naringenin
hmg
hydroxy
Prior art date
Application number
RU99109690/14A
Other languages
English (en)
Other versions
RU2174393C2 (ru
Inventor
Сонг-Хае БОК
Кванг-Хее СОН
Тае-Соок ДЗЕОНГ
Биенг-Мог КВОН
Янг-Коок КИМ
Долл ЧОЙ
Сунг-Ук КИМ
Ки-Хван БАЕ
Йонг-Бок ПАРК
Миунг-Соок ЧОЙ
Ингиу ХВАНГ
Сурк-Сик МООН
Йонг-Коок КВОН
Дзунг-Ах АХН
Еун-Соок ЛИ
Original Assignee
Корея Инститьют Оф Сайенс Энд Текнолоджи
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1019960045735A external-priority patent/KR100213895B1/ko
Application filed by Корея Инститьют Оф Сайенс Энд Текнолоджи filed Critical Корея Инститьют Оф Сайенс Энд Текнолоджи
Publication of RU99109690A publication Critical patent/RU99109690A/ru
Application granted granted Critical
Publication of RU2174393C2 publication Critical patent/RU2174393C2/ru

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Claims (4)

1. Применение нарингина или нарингенина для ингибирования активности 3-гидрокси-3-метилглутарил Коа (HMG-CоА) редуктазы у млекопитающего.
2. Применение по п.1, где млекопитающим является человек.
3. Применение по п. 1, где нарингин или нарингенин вводится млекопитающему в виде композиции, содержащей его, причем указанная композиция выбрана из группы, включающей: фармацевтическую композицию, композицию в виде пищевого продукта и композицию в виде напитка.
4. Применение по п.3, где эффективное количество нарингина или нарингенина, содержащегося в композиции, находится в диапазоне 0,5 - 300 мг/мг массы тела/сут.
RU99109690/14A 1996-10-14 1997-10-13 Нарингин и нарингенин в качестве ингибитора 3-гидрокси-3-метилглутарил коа (hmg-coа) редуктазы RU2174393C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1019960045735A KR100213895B1 (ko) 1996-10-14 1996-10-14 감귤류 과피 추출물, 이로부터 분리 정제된 헤스페리딘 또는 나린진을 포함하는 심혈관 질환 예방및 치료제 조성물
KR1996-45735 1996-10-14
KR96-45735 1996-10-14

Publications (2)

Publication Number Publication Date
RU99109690A true RU99109690A (ru) 2001-02-20
RU2174393C2 RU2174393C2 (ru) 2001-10-10

Family

ID=19477355

Family Applications (2)

Application Number Title Priority Date Filing Date
RU99109602/14A RU2174392C2 (ru) 1996-10-14 1997-10-13 Гесперидин и гесперетин в качестве ингибиторов 3-гидрокси-3-метилглутарил-коа (гмг-коа)-редуктазы
RU99109690/14A RU2174393C2 (ru) 1996-10-14 1997-10-13 Нарингин и нарингенин в качестве ингибитора 3-гидрокси-3-метилглутарил коа (hmg-coа) редуктазы

Family Applications Before (1)

Application Number Title Priority Date Filing Date
RU99109602/14A RU2174392C2 (ru) 1996-10-14 1997-10-13 Гесперидин и гесперетин в качестве ингибиторов 3-гидрокси-3-метилглутарил-коа (гмг-коа)-редуктазы

Country Status (10)

Country Link
US (3) US5792461A (ru)
EP (3) EP1014968B1 (ru)
JP (3) JP2001502320A (ru)
KR (3) KR100213895B1 (ru)
CN (3) CN1104897C (ru)
CA (3) CA2268439C (ru)
DE (3) DE69727707T2 (ru)
HK (2) HK1022104A1 (ru)
RU (2) RU2174392C2 (ru)
WO (3) WO1998016239A1 (ru)

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