RU99109602A - Гесперидин и гесперетин в качестве ингибиторов 3-гидрокси-3-метилглутарил-коа (гмг-коа)-редуктазы - Google Patents

Гесперидин и гесперетин в качестве ингибиторов 3-гидрокси-3-метилглутарил-коа (гмг-коа)-редуктазы

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Publication number
RU99109602A
RU99109602A RU99109602/14A RU99109602A RU99109602A RU 99109602 A RU99109602 A RU 99109602A RU 99109602/14 A RU99109602/14 A RU 99109602/14A RU 99109602 A RU99109602 A RU 99109602A RU 99109602 A RU99109602 A RU 99109602A
Authority
RU
Russia
Prior art keywords
coa
hesperidin
hesperetin
hmg
hydroxy
Prior art date
Application number
RU99109602/14A
Other languages
English (en)
Other versions
RU2174392C2 (ru
Inventor
Сонг-Хае БОК
Кванг-Хее СОН
Тае-Соок ДЗЕОНГ
Биенг-Мог КВОН
Янг-Коок КИМ
Долл ЧОЙ
Сунг-Ук КИМ
Ки-Хван БАЕ
Йонг-Бок ПАРК
Миунг-Соок ЧОЙ
Ингиу ХВАНГ
Сурк-Сик МООН
Йонг-Коок КВОН
Дзунг-Ах АХН
Еун-Соок ЛИ
Original Assignee
Корея Инститьют Оф Сайенс Энд Текнолоджи
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Priority claimed from KR1019960045735A external-priority patent/KR100213895B1/ko
Application filed by Корея Инститьют Оф Сайенс Энд Текнолоджи filed Critical Корея Инститьют Оф Сайенс Энд Текнолоджи
Publication of RU99109602A publication Critical patent/RU99109602A/ru
Application granted granted Critical
Publication of RU2174392C2 publication Critical patent/RU2174392C2/ru

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Claims (4)

1. Применение гесперидина или гесперетина для ингибирования активности 3-гидрокси-3-метилглутарил-КоА(ГМГ-КоА)-редуктазы у млекопитающих.
2. Применение по п.1, где млекопитающим является человек.
3. Применение по п. 1, где гесперидин или гесперетин вводят млекопитающему в виде композиции, содержащей указанные соединения, и указанная композиция выбрана из группы, включающей: фармацевтическую композицию, пищевую композицию и композицию для питья.
4. Применение по п.3, где эффективное количество гесперидина или гесперетина, содержащееся в указанной композиции находится в пределах 0,5 - 300 мг/кг массы тела/день.
RU99109602/14A 1996-10-14 1997-10-13 Гесперидин и гесперетин в качестве ингибиторов 3-гидрокси-3-метилглутарил-коа (гмг-коа)-редуктазы RU2174392C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1019960045735A KR100213895B1 (ko) 1996-10-14 1996-10-14 감귤류 과피 추출물, 이로부터 분리 정제된 헤스페리딘 또는 나린진을 포함하는 심혈관 질환 예방및 치료제 조성물
KR96-45735 1996-10-14
KR1996-45735 1996-10-14

Publications (2)

Publication Number Publication Date
RU99109602A true RU99109602A (ru) 2001-02-20
RU2174392C2 RU2174392C2 (ru) 2001-10-10

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Family Applications (2)

Application Number Title Priority Date Filing Date
RU99109602/14A RU2174392C2 (ru) 1996-10-14 1997-10-13 Гесперидин и гесперетин в качестве ингибиторов 3-гидрокси-3-метилглутарил-коа (гмг-коа)-редуктазы
RU99109690/14A RU2174393C2 (ru) 1996-10-14 1997-10-13 Нарингин и нарингенин в качестве ингибитора 3-гидрокси-3-метилглутарил коа (hmg-coа) редуктазы

Family Applications After (1)

Application Number Title Priority Date Filing Date
RU99109690/14A RU2174393C2 (ru) 1996-10-14 1997-10-13 Нарингин и нарингенин в качестве ингибитора 3-гидрокси-3-метилглутарил коа (hmg-coа) редуктазы

Country Status (10)

Country Link
US (3) US5877208A (ru)
EP (3) EP1014968B1 (ru)
JP (3) JP2001502320A (ru)
KR (3) KR100213895B1 (ru)
CN (3) CN1233182A (ru)
CA (3) CA2268438C (ru)
DE (3) DE69718030T2 (ru)
HK (2) HK1022105A1 (ru)
RU (2) RU2174392C2 (ru)
WO (3) WO1998016220A1 (ru)

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