RU94022485A - Липопептиды из actinoplanes sp, способ их получения и применение - Google Patents

Липопептиды из actinoplanes sp, способ их получения и применение

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Publication number
RU94022485A
RU94022485A RU94022485/04A RU94022485A RU94022485A RU 94022485 A RU94022485 A RU 94022485A RU 94022485/04 A RU94022485/04 A RU 94022485/04A RU 94022485 A RU94022485 A RU 94022485A RU 94022485 A RU94022485 A RU 94022485A
Authority
RU
Russia
Prior art keywords
lipopeptides
actinoplanes
preparing
purification
dsm
Prior art date
Application number
RU94022485/04A
Other languages
English (en)
Other versions
RU2117672C1 (ru
Inventor
Хамманн Петер
De]
Майвес Йоханнес
Зайберт Герхард
Вертеши Ласло
Винк Йоахим
Маркус Астрид
Original Assignee
Хехст АГ (DE)
Хехст АГ
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Publication date
Application filed by Хехст АГ (DE), Хехст АГ filed Critical Хехст АГ (DE)
Publication of RU94022485A publication Critical patent/RU94022485A/ru
Application granted granted Critical
Publication of RU2117672C1 publication Critical patent/RU2117672C1/ru

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/827Actinoplanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Изобретение касается липопептидов с ярко выраженной гомологической последовательностью аминокислот, но с различными радикалами жирных кислот (липидной частью), синтезируемых из Actinoplanes sp. в процессе ферментации и выделяемых из культуральной среды, способов выделения липопептидов из культуральной среды и их очистки, применения липопептидов в качестве фармакологически активных веществ, в частности против грам-положительных бактерий, а также штаммов Actinoplanes sp. DSM 7358 для получения указанных липопептидов.

Claims (1)

  1. Изобретение касается липопептидов с ярко выраженной гомологической последовательностью аминокислот, но с различными радикалами жирных кислот (липидной частью), синтезируемых из Actinoplanes sp. в процессе ферментации и выделяемых из культуральной среды, способов выделения липопептидов из культуральной среды и их очистки, применения липопептидов в качестве фармакологически активных веществ, в частности против грам-положительных бактерий, а также штаммов Actinoplanes sp. DSM 7358 для получения указанных липопептидов.
RU94022485/04A 1993-06-08 1994-06-07 Липопептиды, способ получения, лекарственное средство и штамм actinoplanes sp. dsm 7358 в качестве продуцента липопептидов RU2117672C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4319007 1993-06-08
DEP4319007.3 1993-06-08

Publications (2)

Publication Number Publication Date
RU94022485A true RU94022485A (ru) 1996-04-20
RU2117672C1 RU2117672C1 (ru) 1998-08-20

Family

ID=6489896

Family Applications (1)

Application Number Title Priority Date Filing Date
RU94022485/04A RU2117672C1 (ru) 1993-06-08 1994-06-07 Липопептиды, способ получения, лекарственное средство и штамм actinoplanes sp. dsm 7358 в качестве продуцента липопептидов

Country Status (28)

Country Link
US (1) US6194383B1 (ru)
EP (2) EP0629636B1 (ru)
JP (1) JP2660161B2 (ru)
KR (2) KR0174264B1 (ru)
AT (2) ATE198209T1 (ru)
AU (1) AU672691B2 (ru)
CA (1) CA2125376C (ru)
CY (1) CY2190B1 (ru)
CZ (1) CZ285322B6 (ru)
DE (2) DE59409616D1 (ru)
DK (2) DK0629636T3 (ru)
ES (2) ES2153224T3 (ru)
FI (1) FI942660A (ru)
GR (2) GR3029591T3 (ru)
HK (1) HK1012009A1 (ru)
HU (1) HU217177B (ru)
IL (2) IL109917A (ru)
MA (1) MA23216A1 (ru)
NO (1) NO942110L (ru)
NZ (1) NZ260682A (ru)
OA (1) OA10066A (ru)
PL (2) PL179581B1 (ru)
PT (1) PT864584E (ru)
RU (1) RU2117672C1 (ru)
SK (1) SK281830B6 (ru)
TW (1) TW455591B (ru)
UY (1) UY23762A1 (ru)
ZA (1) ZA943983B (ru)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2789838C1 (ru) * 2022-11-25 2023-02-13 Общество С Ограниченной Ответственностью "Промомед Рус" Новый штамм-продуцент рамопланина actinoplanes ramoplaninifer

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4411025A1 (de) * 1994-03-30 1995-10-05 Hoechst Ag Lipopeptid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
DE19807972A1 (de) * 1998-02-25 1999-08-26 Hoechst Marion Roussel De Gmbh Lipopeptidantibiotika-Calciumsalze, Verfahren zu ihrer Herstellung und Verwendung
KR100291406B1 (ko) * 1999-05-13 2001-05-15 이길정 직거 염색기용 기어박스
KR100423751B1 (ko) * 1999-05-18 2004-03-22 심선희 지그염색기의 직물이송속도 유지장치
KR100331966B1 (ko) * 1999-10-23 2002-04-10 윤기룡 염색된 직물의 직물권취장치
US6696412B1 (en) * 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US6511962B1 (en) * 2000-07-17 2003-01-28 Micrologix Biotech Inc. Derivatives of laspartomycin and preparation and use thereof
US6750199B2 (en) 2000-07-17 2004-06-15 Micrologix Biotech Inc. Antimicrobial sulfonamide derivatives of lipopeptide antibiotics
US6737403B2 (en) 2000-07-17 2004-05-18 Micrologix Biotech Inc. Derivatives of laspartomycin and preparation and use thereof
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
AU2003202878B2 (en) 2002-01-03 2008-07-31 Migenix Inc. Dab9 derivatives of lipopeptide antibiotics and methods of making and using the same
US20040157803A1 (en) * 2002-03-04 2004-08-12 Williams Deryck J. Nematicidal fatty acid and fatty acid ester related compounds
US6887900B2 (en) 2002-03-04 2005-05-03 Divergence, Inc. Nematicidal compositions and methods
NZ544750A (en) 2003-07-17 2009-06-26 Migenix Inc Compositions of amphomycin or aspartocin based lipopeptide antibiotic derivatives and methods of use thereof
US7368629B2 (en) * 2004-02-04 2008-05-06 Divergence, Inc. Nucleic acids encoding anthelmintic agents and plants made therefrom
DE102004060750A1 (de) 2004-12-15 2006-07-13 Sanofi-Aventis Deutschland Gmbh Verfahren zur Deacylierung von Lipopeptiden
GB0821540D0 (en) 2008-11-25 2008-12-31 Merlion Pharmaceuticals Pte Ltd Lipopeptide compounds and their use
US8835382B2 (en) 2009-11-23 2014-09-16 Cubist Pharmaceuticals, Inc. Lipopeptide compositions and related methods
KR101151878B1 (ko) 2010-06-08 2012-05-31 미원상사주식회사 지방산 트리펩타이드염 및 이를 함유하는 항균 조성물
WO2013012101A1 (ko) * 2011-07-15 2013-01-24 미원상사주식회사 지방산 트리펩타이드염 및 이를 함유하는 항균 조성물
FR2980802B1 (fr) * 2011-10-03 2014-12-26 Univ Lille 1 Sciences Et Technologies Ustl Procede de production de biosurfactants et dispositif de mise en œuvre

Family Cites Families (3)

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Publication number Priority date Publication date Assignee Title
US4000397A (en) 1975-03-21 1976-12-28 Spectra-Physics, Inc. Signal processor method and apparatus
US4001397A (en) * 1975-08-11 1977-01-04 Pfizer Inc. Antibiotic compound 41,012
DE4411025A1 (de) * 1994-03-30 1995-10-05 Hoechst Ag Lipopeptid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2789838C1 (ru) * 2022-11-25 2023-02-13 Общество С Ограниченной Ответственностью "Промомед Рус" Новый штамм-продуцент рамопланина actinoplanes ramoplaninifer

Also Published As

Publication number Publication date
SK281830B6 (sk) 2001-08-06
EP0864584A1 (de) 1998-09-16
AU6462094A (en) 1994-12-15
UY23762A1 (es) 1994-05-03
FI942660A (fi) 1994-12-09
DE59407475D1 (de) 1999-01-28
JP2660161B2 (ja) 1997-10-08
IL109917A (en) 2001-03-19
EP0629636A1 (de) 1994-12-21
ES2127312T3 (es) 1999-04-16
DK0864584T3 (da) 2001-02-05
EP0629636B1 (de) 1998-12-16
JPH0797394A (ja) 1995-04-11
DE59409616D1 (de) 2001-01-25
RU2117672C1 (ru) 1998-08-20
CZ138194A3 (en) 1994-12-15
EP0864584B1 (de) 2000-12-20
CZ285322B6 (cs) 1999-07-14
PL180230B1 (pl) 2001-01-31
GR3029591T3 (en) 1999-06-30
HU217177B (hu) 1999-12-28
HK1012009A1 (en) 1999-07-23
GR3035204T3 (en) 2001-04-30
ZA943983B (en) 1995-01-27
FI942660A0 (fi) 1994-06-06
KR100319563B1 (ko) 2002-02-19
KR0174264B1 (ko) 1999-02-01
AU672691B2 (en) 1996-10-10
MA23216A1 (fr) 1994-12-31
IL109917A0 (en) 1994-10-07
ATE174604T1 (de) 1999-01-15
DK0629636T3 (da) 1999-08-23
PT864584E (pt) 2001-05-31
HU9401465D0 (en) 1994-08-29
SK68594A3 (en) 1995-01-12
IL125450A0 (en) 1999-03-12
OA10066A (fr) 1996-10-14
ATE198209T1 (de) 2001-01-15
KR950000890A (ko) 1995-01-03
HUT69937A (en) 1995-09-28
TW455591B (en) 2001-09-21
NO942110D0 (no) 1994-06-07
PL303716A1 (en) 1994-12-12
CA2125376C (en) 2000-08-08
CA2125376A1 (en) 1994-12-09
PL179581B1 (pl) 2000-09-29
US6194383B1 (en) 2001-02-27
ES2153224T3 (es) 2001-02-16
NO942110L (no) 1994-12-09
NZ260682A (en) 1995-11-27
CY2190B1 (en) 2002-11-08

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20030608