ES2127312T3 - Lipopeptidos de actinoplanes sp. con actividad farmacologica, procedimiento para su preparacion y utilizacion de los mismos. - Google Patents

Lipopeptidos de actinoplanes sp. con actividad farmacologica, procedimiento para su preparacion y utilizacion de los mismos.

Info

Publication number
ES2127312T3
ES2127312T3 ES94108443T ES94108443T ES2127312T3 ES 2127312 T3 ES2127312 T3 ES 2127312T3 ES 94108443 T ES94108443 T ES 94108443T ES 94108443 T ES94108443 T ES 94108443T ES 2127312 T3 ES2127312 T3 ES 2127312T3
Authority
ES
Spain
Prior art keywords
actinoplanes
lipopeptides
procedure
preparation
pharmacological activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94108443T
Other languages
English (en)
Inventor
Peter Dr Hammann
Johannes Dr Meiwes
Gerhard Prof Dr Seibert
Laszlo Dr Vertesy
Joachim Dr Wink
Astrid Dr Markus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2127312T3 publication Critical patent/ES2127312T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/827—Actinoplanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

LA INVENCION SE REFIERE A LIPOPEPTIDO CON SECUENCIAS DE AMINOACIDOS MUY HOMOLOGA, INCLUSO CON ESTERES DE ACIDO GRASO DIFERENTES (PORCION LIPIDA), QUE SON SINTERIZADOS A PARTIR DE ACTINOPLANOS O DURANTE LA FERMENTACION Y EN DONDE SE DISPONE DE UN MEDIO DE CULTIVO, UN PROCESO PARA EL AISLAMIENTO DEL LIPOPEPTIDO A PARTIR DEL MEDIO DE CULTIVO Y SU PURIFICACION, LA UTILIZACION DEL LIPOPEPTIDO COMO SUSTANCIA ACTIVA FARMACOLOGICA, EN PARTICULAR CONTRA BACTERIAS POSITIVAS, COMO ACTINOPLANOS SEGUN DSM 7358 PARA LA ELABORACION DEL LIPOPEPTIDO ANTES MENCIONADO.
ES94108443T 1993-06-08 1994-06-01 Lipopeptidos de actinoplanes sp. con actividad farmacologica, procedimiento para su preparacion y utilizacion de los mismos. Expired - Lifetime ES2127312T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4319007 1993-06-08

Publications (1)

Publication Number Publication Date
ES2127312T3 true ES2127312T3 (es) 1999-04-16

Family

ID=6489896

Family Applications (2)

Application Number Title Priority Date Filing Date
ES94108443T Expired - Lifetime ES2127312T3 (es) 1993-06-08 1994-06-01 Lipopeptidos de actinoplanes sp. con actividad farmacologica, procedimiento para su preparacion y utilizacion de los mismos.
ES98110484T Expired - Lifetime ES2153224T3 (es) 1993-06-08 1994-06-01 Lipopeptidos procedentes de actinoplanes sp. con actividad farmacologica, procedimiento para su preparacion y su utilizacion.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES98110484T Expired - Lifetime ES2153224T3 (es) 1993-06-08 1994-06-01 Lipopeptidos procedentes de actinoplanes sp. con actividad farmacologica, procedimiento para su preparacion y su utilizacion.

Country Status (28)

Country Link
US (1) US6194383B1 (es)
EP (2) EP0629636B1 (es)
JP (1) JP2660161B2 (es)
KR (2) KR0174264B1 (es)
AT (2) ATE198209T1 (es)
AU (1) AU672691B2 (es)
CA (1) CA2125376C (es)
CY (1) CY2190B1 (es)
CZ (1) CZ285322B6 (es)
DE (2) DE59409616D1 (es)
DK (2) DK0629636T3 (es)
ES (2) ES2127312T3 (es)
FI (1) FI942660A (es)
GR (2) GR3029591T3 (es)
HK (1) HK1012009A1 (es)
HU (1) HU217177B (es)
IL (2) IL109917A (es)
MA (1) MA23216A1 (es)
NO (1) NO942110L (es)
NZ (1) NZ260682A (es)
OA (1) OA10066A (es)
PL (2) PL180230B1 (es)
PT (1) PT864584E (es)
RU (1) RU2117672C1 (es)
SK (1) SK281830B6 (es)
TW (1) TW455591B (es)
UY (1) UY23762A1 (es)
ZA (1) ZA943983B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4411025A1 (de) * 1994-03-30 1995-10-05 Hoechst Ag Lipopeptid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
DE19807972A1 (de) 1998-02-25 1999-08-26 Hoechst Marion Roussel De Gmbh Lipopeptidantibiotika-Calciumsalze, Verfahren zu ihrer Herstellung und Verwendung
KR100291406B1 (ko) * 1999-05-13 2001-05-15 이길정 직거 염색기용 기어박스
KR100423751B1 (ko) * 1999-05-18 2004-03-22 심선희 지그염색기의 직물이송속도 유지장치
KR100331966B1 (ko) * 1999-10-23 2002-04-10 윤기룡 염색된 직물의 직물권취장치
US6696412B1 (en) * 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US6511962B1 (en) 2000-07-17 2003-01-28 Micrologix Biotech Inc. Derivatives of laspartomycin and preparation and use thereof
US6737403B2 (en) 2000-07-17 2004-05-18 Micrologix Biotech Inc. Derivatives of laspartomycin and preparation and use thereof
US6750199B2 (en) 2000-07-17 2004-06-15 Micrologix Biotech Inc. Antimicrobial sulfonamide derivatives of lipopeptide antibiotics
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
AU2003202878B2 (en) 2002-01-03 2008-07-31 Migenix Inc. Dab9 derivatives of lipopeptide antibiotics and methods of making and using the same
US6887900B2 (en) 2002-03-04 2005-05-03 Divergence, Inc. Nematicidal compositions and methods
US20040157803A1 (en) * 2002-03-04 2004-08-12 Williams Deryck J. Nematicidal fatty acid and fatty acid ester related compounds
EP1656390A2 (en) * 2003-07-17 2006-05-17 Migenix Inc. Compositions of lipopeptide antibiotic derivatives and methods of use thereof
US7368629B2 (en) * 2004-02-04 2008-05-06 Divergence, Inc. Nucleic acids encoding anthelmintic agents and plants made therefrom
DE102004060750A1 (de) 2004-12-15 2006-07-13 Sanofi-Aventis Deutschland Gmbh Verfahren zur Deacylierung von Lipopeptiden
GB0821540D0 (en) 2008-11-25 2008-12-31 Merlion Pharmaceuticals Pte Ltd Lipopeptide compounds and their use
FI2504353T4 (fi) 2009-11-23 2023-11-30 Cubist Pharmaceuticals Llc Lipopeptidikoostumukset ja vastaavat menetelmät
KR101151878B1 (ko) 2010-06-08 2012-05-31 미원상사주식회사 지방산 트리펩타이드염 및 이를 함유하는 항균 조성물
WO2013012101A1 (ko) * 2011-07-15 2013-01-24 미원상사주식회사 지방산 트리펩타이드염 및 이를 함유하는 항균 조성물
FR2980802B1 (fr) * 2011-10-03 2014-12-26 Univ Lille 1 Sciences Et Technologies Ustl Procede de production de biosurfactants et dispositif de mise en œuvre

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4000397A (en) 1975-03-21 1976-12-28 Spectra-Physics, Inc. Signal processor method and apparatus
US4001397A (en) * 1975-08-11 1977-01-04 Pfizer Inc. Antibiotic compound 41,012
DE4411025A1 (de) * 1994-03-30 1995-10-05 Hoechst Ag Lipopeptid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung

Also Published As

Publication number Publication date
MA23216A1 (fr) 1994-12-31
CY2190B1 (en) 2002-11-08
FI942660A (fi) 1994-12-09
ES2153224T3 (es) 2001-02-16
DK0629636T3 (da) 1999-08-23
NO942110L (no) 1994-12-09
NZ260682A (en) 1995-11-27
GR3035204T3 (en) 2001-04-30
EP0629636A1 (de) 1994-12-21
HU9401465D0 (en) 1994-08-29
PL303716A1 (en) 1994-12-12
GR3029591T3 (en) 1999-06-30
IL109917A0 (en) 1994-10-07
OA10066A (fr) 1996-10-14
CA2125376C (en) 2000-08-08
KR950000890A (ko) 1995-01-03
DK0864584T3 (da) 2001-02-05
RU94022485A (ru) 1996-04-20
ATE198209T1 (de) 2001-01-15
SK68594A3 (en) 1995-01-12
CZ138194A3 (en) 1994-12-15
FI942660A0 (fi) 1994-06-06
EP0864584B1 (de) 2000-12-20
US6194383B1 (en) 2001-02-27
JPH0797394A (ja) 1995-04-11
EP0864584A1 (de) 1998-09-16
EP0629636B1 (de) 1998-12-16
SK281830B6 (sk) 2001-08-06
NO942110D0 (no) 1994-06-07
CZ285322B6 (cs) 1999-07-14
DE59407475D1 (de) 1999-01-28
PL179581B1 (pl) 2000-09-29
HUT69937A (en) 1995-09-28
IL125450A0 (en) 1999-03-12
IL109917A (en) 2001-03-19
PL180230B1 (pl) 2001-01-31
HK1012009A1 (en) 1999-07-23
PT864584E (pt) 2001-05-31
ZA943983B (en) 1995-01-27
HU217177B (hu) 1999-12-28
JP2660161B2 (ja) 1997-10-08
ATE174604T1 (de) 1999-01-15
AU6462094A (en) 1994-12-15
AU672691B2 (en) 1996-10-10
UY23762A1 (es) 1994-05-03
RU2117672C1 (ru) 1998-08-20
TW455591B (en) 2001-09-21
DE59409616D1 (de) 2001-01-25
KR0174264B1 (ko) 1999-02-01
KR100319563B1 (ko) 2002-02-19
CA2125376A1 (en) 1994-12-09

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