RU2330024C2 - Ингибирующие cdk-киназы пиримидины, способ их получения и их применение в качестве лекарственных средств - Google Patents
Ингибирующие cdk-киназы пиримидины, способ их получения и их применение в качестве лекарственных средств Download PDFInfo
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- RU2330024C2 RU2330024C2 RU2003136080/04A RU2003136080A RU2330024C2 RU 2330024 C2 RU2330024 C2 RU 2330024C2 RU 2003136080/04 A RU2003136080/04 A RU 2003136080/04A RU 2003136080 A RU2003136080 A RU 2003136080A RU 2330024 C2 RU2330024 C2 RU 2330024C2
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- alkyl
- cycloalkyl
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- phenyl
- hydroxy
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- FLVFPAIGVBQGET-UHFFFAOYSA-N CN(CC1)CC1O Chemical compound CN(CC1)CC1O FLVFPAIGVBQGET-UHFFFAOYSA-N 0.000 description 1
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- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10127581.1 | 2001-05-29 | ||
| DE10127581A DE10127581A1 (de) | 2001-05-29 | 2001-05-29 | CDK inhibitorische Pyrimidine, deren Herstellung und Verwendung als Arzneimittel |
| DE10212098.6 | 2002-03-11 | ||
| DE10212098A DE10212098A1 (de) | 2002-03-11 | 2002-03-11 | CDK inhibitorische Pyrimidine, deren Herstellung und Verwendung als Arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2003136080A RU2003136080A (ru) | 2005-05-20 |
| RU2330024C2 true RU2330024C2 (ru) | 2008-07-27 |
Family
ID=26009483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2003136080/04A RU2330024C2 (ru) | 2001-05-29 | 2002-05-23 | Ингибирующие cdk-киназы пиримидины, способ их получения и их применение в качестве лекарственных средств |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US7235561B2 (enExample) |
| EP (1) | EP1392662B1 (enExample) |
| JP (1) | JP4291135B2 (enExample) |
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| AR (1) | AR036035A1 (enExample) |
| AT (1) | ATE420077T1 (enExample) |
| AU (1) | AU2002312933B2 (enExample) |
| BR (1) | BR0209774A (enExample) |
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| DE (1) | DE50213202D1 (enExample) |
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| HR (1) | HRP20031081A2 (enExample) |
| IL (1) | IL159120A0 (enExample) |
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| MX (1) | MXPA03010810A (enExample) |
| NO (1) | NO327129B1 (enExample) |
| NZ (1) | NZ529654A (enExample) |
| PL (1) | PL367130A1 (enExample) |
| RS (1) | RS94703A (enExample) |
| RU (1) | RU2330024C2 (enExample) |
| WO (1) | WO2002096888A1 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2647849C2 (ru) * | 2011-11-29 | 2018-03-21 | Дженентек, Инк. | Производные 2-(фенил или пирид-3-ил)аминопиримидина в качестве модуляторов богатой лейцином повторной киназы 2 (lrrk2) для лечения болезни паркинсона |
| US11103507B2 (en) | 2018-12-28 | 2021-08-31 | Deciphera Pharmaceuticals, Llc | Methods of treating disorders using CSF1R inhibitors |
| RU2804638C2 (ru) * | 2017-08-23 | 2023-10-03 | Спринт Биосайенс Аб | Пиридинаминпиридоны и пиримидинаминпиридоны |
| US12447149B2 (en) | 2023-12-08 | 2025-10-21 | Deciphera Pharmaceuticals, Llc | Formulations of vimseltinib |
Families Citing this family (134)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL367130A1 (en) * | 2001-05-29 | 2005-02-21 | Schering Aktiengesellschaft | Cdk inhibiting pyrimidines, production thereof and their use as medicaments |
| US20030139435A1 (en) | 2001-06-26 | 2003-07-24 | Gulzar Ahmed | N-heterocyclic inhibitors of TNF-alpha expression |
| EP1438053B1 (de) | 2001-10-17 | 2008-09-10 | Boehringer Ingelheim Pharma GmbH & Co.KG | Pyrimidinderivate, arzneimittel enthaltend diese verbindungen, deren verwendung und verfahren zu ihrer herstellung |
| EP1453516A2 (de) | 2001-10-17 | 2004-09-08 | Boehringer Ingelheim Pharma GmbH & Co.KG | 5-substituierte 4-amino-2-phenylamino-pyrimdinderivate und ihre verwendung als beta-amyloid modulatoren |
| WO2003055489A1 (en) * | 2001-12-21 | 2003-07-10 | Bayer Pharmaceuticals Corporation | 2,4-diamino-pyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents |
| TWI329105B (en) | 2002-02-01 | 2010-08-21 | Rigel Pharmaceuticals Inc | 2,4-pyrimidinediamine compounds and their uses |
| GB0205693D0 (en) | 2002-03-09 | 2002-04-24 | Astrazeneca Ab | Chemical compounds |
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- 2002-05-23 JP JP2003500067A patent/JP4291135B2/ja not_active Expired - Fee Related
- 2002-05-23 KR KR1020037015597A patent/KR100874791B1/ko not_active Expired - Fee Related
- 2002-05-23 MX MXPA03010810A patent/MXPA03010810A/es active IP Right Grant
- 2002-05-23 DE DE50213202T patent/DE50213202D1/de not_active Expired - Lifetime
- 2002-05-23 RS YUP-947/03A patent/RS94703A/sr unknown
- 2002-05-23 IL IL15912002A patent/IL159120A0/xx unknown
- 2002-05-23 EP EP02738100A patent/EP1392662B1/de not_active Expired - Lifetime
- 2002-05-23 CN CNB02814886XA patent/CN100480242C/zh not_active Expired - Fee Related
- 2002-05-23 NZ NZ529654A patent/NZ529654A/en unknown
- 2002-05-23 WO PCT/EP2002/005669 patent/WO2002096888A1/de not_active Ceased
- 2002-05-23 BR BR0209774-5A patent/BR0209774A/pt not_active IP Right Cessation
- 2002-05-23 HR HR20031081A patent/HRP20031081A2/hr not_active Application Discontinuation
- 2002-05-23 AT AT02738100T patent/ATE420077T1/de not_active IP Right Cessation
- 2002-05-23 ES ES02738100T patent/ES2320204T3/es not_active Expired - Lifetime
- 2002-05-23 AU AU2002312933A patent/AU2002312933B2/en not_active Ceased
- 2002-05-23 CA CA002449118A patent/CA2449118A1/en not_active Abandoned
- 2002-05-23 RU RU2003136080/04A patent/RU2330024C2/ru active
- 2002-05-23 ME MEP-134/08A patent/MEP13408A/xx unknown
- 2002-05-29 AR ARP020102001A patent/AR036035A1/es unknown
- 2002-05-29 US US10/156,759 patent/US7235561B2/en not_active Expired - Fee Related
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| RU2647849C2 (ru) * | 2011-11-29 | 2018-03-21 | Дженентек, Инк. | Производные 2-(фенил или пирид-3-ил)аминопиримидина в качестве модуляторов богатой лейцином повторной киназы 2 (lrrk2) для лечения болезни паркинсона |
| RU2804638C2 (ru) * | 2017-08-23 | 2023-10-03 | Спринт Биосайенс Аб | Пиридинаминпиридоны и пиримидинаминпиридоны |
| US11103507B2 (en) | 2018-12-28 | 2021-08-31 | Deciphera Pharmaceuticals, Llc | Methods of treating disorders using CSF1R inhibitors |
| US11679110B2 (en) | 2018-12-28 | 2023-06-20 | Deciphera Pharmaceuticals, Llc | Methods of treating disorders using CSF1R inhibitors |
| US12285430B2 (en) | 2018-12-28 | 2025-04-29 | Deciphera Pharmaceuticals, Llc | Methods of treating disorders using CSF1R inhibitors |
| US12485120B2 (en) | 2018-12-28 | 2025-12-02 | Deciphera Pharmaceuticals, Llc | Methods of treating disorders using CSF1R inhibitors |
| RU2826488C1 (ru) * | 2020-01-10 | 2024-09-11 | Ханчжоу Инногейт Фарма Ко., Лтд. | Полициклическое соединение, действующее как ингибитор киназы |
| US12447149B2 (en) | 2023-12-08 | 2025-10-21 | Deciphera Pharmaceuticals, Llc | Formulations of vimseltinib |
| US12509443B2 (en) | 2025-08-14 | 2025-12-30 | Deciphera Pharmaceuticals, Llc | CSF-1R inhibitors and methods of use thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| AR036035A1 (es) | 2004-08-04 |
| US7598260B2 (en) | 2009-10-06 |
| MXPA03010810A (es) | 2004-03-22 |
| AU2002312933B2 (en) | 2007-12-06 |
| WO2002096888A1 (de) | 2002-12-05 |
| IL159120A0 (en) | 2004-05-12 |
| US7291624B2 (en) | 2007-11-06 |
| NO20035298D0 (no) | 2003-11-28 |
| NZ529654A (en) | 2005-12-23 |
| CA2449118A1 (en) | 2002-12-05 |
| HRP20031081A2 (en) | 2005-10-31 |
| DE50213202D1 (de) | 2009-02-26 |
| US20080039447A1 (en) | 2008-02-14 |
| JP2004535414A (ja) | 2004-11-25 |
| CO5540316A2 (es) | 2005-07-29 |
| US20040102630A1 (en) | 2004-05-27 |
| MEP13408A (en) | 2010-06-10 |
| KR20040030645A (ko) | 2004-04-09 |
| ATE420077T1 (de) | 2009-01-15 |
| PL367130A1 (en) | 2005-02-21 |
| BR0209774A (pt) | 2004-06-01 |
| RS94703A (sr) | 2007-02-05 |
| NO327129B1 (no) | 2009-04-27 |
| KR100874791B1 (ko) | 2008-12-18 |
| EP1392662B1 (de) | 2009-01-07 |
| RU2003136080A (ru) | 2005-05-20 |
| ES2320204T3 (es) | 2009-05-20 |
| US20040224966A1 (en) | 2004-11-11 |
| CN1633419A (zh) | 2005-06-29 |
| EP1392662A1 (de) | 2004-03-03 |
| US7235561B2 (en) | 2007-06-26 |
| CN100480242C (zh) | 2009-04-22 |
| JP4291135B2 (ja) | 2009-07-08 |
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