MXPA03010810A - Pirimidinas inhibidoras de cdk, su obtencion y su uso como medicamentos. - Google Patents

Pirimidinas inhibidoras de cdk, su obtencion y su uso como medicamentos.

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Publication number
MXPA03010810A
MXPA03010810A MXPA03010810A MXPA03010810A MXPA03010810A MX PA03010810 A MXPA03010810 A MX PA03010810A MX PA03010810 A MXPA03010810 A MX PA03010810A MX PA03010810 A MXPA03010810 A MX PA03010810A MX PA03010810 A MXPA03010810 A MX PA03010810A
Authority
MX
Mexico
Prior art keywords
production
medicaments
cdk inhibiting
inhibiting pyrimidines
pyrimidines
Prior art date
Application number
MXPA03010810A
Other languages
English (en)
Inventor
Brumby Thomas
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10127581A external-priority patent/DE10127581A1/de
Priority claimed from DE10212098A external-priority patent/DE10212098A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of MXPA03010810A publication Critical patent/MXPA03010810A/es

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    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3

Abstract

La invencion se refiere a derivados de pirimidina de formula general (I), en donde R1, R2, X, A y B se definen como en la descripcion, para su uso como inhibidores de la cinasa dependiente de la ciclina. La invencion se refiere ademas a su obtencion asi como a su uso como medicamento para el tratamiento de varias enfermedades.
MXPA03010810A 2001-05-29 2002-05-23 Pirimidinas inhibidoras de cdk, su obtencion y su uso como medicamentos. MXPA03010810A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10127581A DE10127581A1 (de) 2001-05-29 2001-05-29 CDK inhibitorische Pyrimidine, deren Herstellung und Verwendung als Arzneimittel
DE10212098A DE10212098A1 (de) 2002-03-11 2002-03-11 CDK inhibitorische Pyrimidine, deren Herstellung und Verwendung als Arzneimittel
PCT/EP2002/005669 WO2002096888A1 (de) 2001-05-29 2002-05-23 Cdk inhibitorische pyrimidine, deren herstellung und verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
MXPA03010810A true MXPA03010810A (es) 2004-03-22

Family

ID=26009483

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03010810A MXPA03010810A (es) 2001-05-29 2002-05-23 Pirimidinas inhibidoras de cdk, su obtencion y su uso como medicamentos.

Country Status (23)

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US (3) US7235561B2 (es)
EP (1) EP1392662B1 (es)
JP (1) JP4291135B2 (es)
KR (1) KR100874791B1 (es)
CN (1) CN100480242C (es)
AR (1) AR036035A1 (es)
AT (1) ATE420077T1 (es)
AU (1) AU2002312933B2 (es)
BR (1) BR0209774A (es)
CA (1) CA2449118A1 (es)
CO (1) CO5540316A2 (es)
DE (1) DE50213202D1 (es)
ES (1) ES2320204T3 (es)
HR (1) HRP20031081A2 (es)
IL (1) IL159120A0 (es)
ME (1) MEP13408A (es)
MX (1) MXPA03010810A (es)
NO (1) NO327129B1 (es)
NZ (1) NZ529654A (es)
PL (1) PL367130A1 (es)
RS (1) RS94703A (es)
RU (1) RU2330024C2 (es)
WO (1) WO2002096888A1 (es)

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JP4510442B2 (ja) * 2001-06-26 2010-07-21 ブリストル−マイヤーズ スクイブ カンパニー ＴＮＦ−α発現のＮ−ヘテロ環インヒビター
EP1453516A2 (de) 2001-10-17 2004-09-08 Boehringer Ingelheim Pharma GmbH & Co.KG 5-substituierte 4-amino-2-phenylamino-pyrimdinderivate und ihre verwendung als beta-amyloid modulatoren
EP2332924A1 (de) 2001-10-17 2011-06-15 Boehringer Ingelheim Pharma GmbH & Co. KG Pyrimidinderivate, Arzneimittel enthaltend diese Verbindungen, deren Verwendung und Verfahren zu ihrer Herstellung
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GB0311276D0 (en) 2003-05-16 2003-06-18 Astrazeneca Ab Chemical compounds
GB0311274D0 (en) 2003-05-16 2003-06-18 Astrazeneca Ab Chemical compounds
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