RU2297998C2 - Способ получения 4-фенилмасляной кислоты и ее солей (варианты) - Google Patents

Способ получения 4-фенилмасляной кислоты и ее солей (варианты) Download PDF

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Publication number
RU2297998C2
RU2297998C2 RU2003136765/04A RU2003136765A RU2297998C2 RU 2297998 C2 RU2297998 C2 RU 2297998C2 RU 2003136765/04 A RU2003136765/04 A RU 2003136765/04A RU 2003136765 A RU2003136765 A RU 2003136765A RU 2297998 C2 RU2297998 C2 RU 2297998C2
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Russia
Prior art keywords
catalyst
formula
compound
butyrolactone
benzene
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RU2003136765/04A
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English (en)
Russian (ru)
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RU2003136765A (ru
Inventor
Станислав Р. БУРЗИНСКИЙ (US)
Станислав Р. Бурзинский
Лешек МУСЯЛ (US)
Лешек МУСЯЛ
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Станислав Р. Бурзинский
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Application filed by Станислав Р. Бурзинский filed Critical Станислав Р. Бурзинский
Publication of RU2003136765A publication Critical patent/RU2003136765A/ru
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Publication of RU2297998C2 publication Critical patent/RU2297998C2/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/353—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
RU2003136765/04A 2001-05-21 2002-05-02 Способ получения 4-фенилмасляной кислоты и ее солей (варианты) RU2297998C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/862,074 US6372938B1 (en) 2001-05-21 2001-05-21 Synthesis of 4-phenylbutyric acid
US09/862,074 2001-05-21

Publications (2)

Publication Number Publication Date
RU2003136765A RU2003136765A (ru) 2005-04-10
RU2297998C2 true RU2297998C2 (ru) 2007-04-27

Family

ID=25337569

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2003136765/04A RU2297998C2 (ru) 2001-05-21 2002-05-02 Способ получения 4-фенилмасляной кислоты и ее солей (варианты)

Country Status (12)

Country Link
US (1) US6372938B1 (enExample)
EP (1) EP1404638B1 (enExample)
JP (1) JP4338401B2 (enExample)
KR (1) KR100905139B1 (enExample)
CN (1) CN1266105C (enExample)
AT (1) ATE517857T1 (enExample)
CA (1) CA2447803C (enExample)
HU (1) HU229996B1 (enExample)
IL (2) IL158914A0 (enExample)
PL (1) PL201802B1 (enExample)
RU (1) RU2297998C2 (enExample)
WO (1) WO2002094756A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1291015A1 (en) * 2001-09-10 2003-03-12 Lunamed AG Dosage forms having prolonged active ingredient release
US7115782B2 (en) * 2002-06-03 2006-10-03 Showa Denko K.K. Process for producing aromatic compounds by Friedel-Crafts reaction
US20060045912A1 (en) * 2004-08-30 2006-03-02 Peter Truog 4-phenylbutyric acid controlled-release formulations for therapeutic use
US20070004805A1 (en) * 2005-07-01 2007-01-04 Navinta Llc Process for preparation of liquid dosage form containing sodium 4-phenylbutyrate
WO2007035029A1 (en) * 2005-09-23 2007-03-29 Sk Holdings Co., Ltd. Pharmaceutical composition for prevention and treatment of drug or alcohol addiction or bipolar disorder using sodium phenylbutyrate
BR112012025714A2 (pt) * 2010-04-06 2015-09-08 Bayer Ip Gmbh uso de ácido 4-fenilbutírico e/ou sais do mesmo para aumentar a tolerância a estresse de plantas
KR101374241B1 (ko) * 2010-11-17 2014-03-14 전북대학교병원 페닐부틸산（４－ｐｈｅｎｙｌｂｕｔｙｒｉｃ ａｃｉｄ）또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는, 천식 치료용 약학적 조성물
EP2599477A1 (en) 2011-11-30 2013-06-05 Lunamed AG 4-Phenylbutyric acid sustained release formulation
FR2993141B1 (fr) 2012-07-11 2014-11-28 Inst Rech Developpement Ird Utilisation de l'acide 4-phenylbutyrique pour ameliorer la tolerance des plantes aux bioagresseurs
CN103304402B (zh) * 2013-05-24 2015-04-22 苏州诚和医药化学有限公司 一种制备4-苯-1-丁酸的方法
CN103304403B (zh) * 2013-05-24 2015-04-22 苏州诚和医药化学有限公司 一种4-苯-1-丁酸的合成方法
US9914692B2 (en) * 2016-05-25 2018-03-13 Horizon Therapeutics, Llc Procedure for the preparation of 4-phenyl butyrate and uses thereof
CN106117045A (zh) * 2016-06-22 2016-11-16 北京阳光诺和药物研究有限公司 一种苯基丁酸的纯化方法
CN108530290A (zh) * 2018-06-04 2018-09-14 福州华博立乐新材料科技有限公司 一种4-苯基-1-丁酸的合成方法
CN110317132B (zh) * 2019-07-26 2021-09-10 南京工业大学 一种苯丁酸钠的制备方法
FR3110336B1 (fr) 2020-05-20 2022-12-23 Inst Des Sciences Et Industries Du Vivant Et De Lenvir Utilisation de l’Acide 4-phénylbutyrique et/ou de l’Acide 3-phénylbutyrique et/ou de l’Acide 2-phénylbutyrique pour la Prévention et le Traitement des Maladies Cryptogamiques
WO2024200617A1 (en) * 2023-03-28 2024-10-03 Dipharma Francis S.R.L. Process and intermediates for preparing a drug for the treatment of urea cycle disorders
IT202300019125A1 (it) * 2023-09-18 2025-03-18 Dipharma Francis Srl Metodo di purificazione di un farmaco usato per il trattamento di disturbi del ciclo dell’urea

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU334213A1 (ru) * Ч. Ш. Кадыров , В. А. Барашкин Способ получения замещенных 2-(гидроксифенил)масляных кислот

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6037376A (en) 1991-10-21 2000-03-14 The United States Of America As Represented By The Department Of Health And Human Services Methods for therapy of cancer

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU334213A1 (ru) * Ч. Ш. Кадыров , В. А. Барашкин Способ получения замещенных 2-(гидроксифенил)масляных кислот

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHRISTIAN R.V., Journal of the Chemical Society, 1952, v.74, p.1591. ЗАХАРКИНА Л.И., АНИКИНА Е.В., Известия Академии наук СССР, сер. хим., 1987, №2, с.367-370. TRUCE W.E, Journal of the Chemical Society, 1952, v.74, p.4721. *

Also Published As

Publication number Publication date
JP4338401B2 (ja) 2009-10-07
WO2002094756A1 (en) 2002-11-28
HUP0400053A3 (en) 2006-01-30
CA2447803C (en) 2009-04-07
PL201802B1 (pl) 2009-05-29
IL158914A0 (en) 2004-05-12
RU2003136765A (ru) 2005-04-10
ATE517857T1 (de) 2011-08-15
PL364646A1 (en) 2004-12-13
EP1404638B1 (en) 2011-07-27
EP1404638A1 (en) 2004-04-07
KR20040025679A (ko) 2004-03-24
CN1511133A (zh) 2004-07-07
HK1065996A1 (en) 2005-03-11
KR100905139B1 (ko) 2009-06-29
CN1266105C (zh) 2006-07-26
HUP0400053A2 (hu) 2004-04-28
JP2004527577A (ja) 2004-09-09
US6372938B1 (en) 2002-04-16
CA2447803A1 (en) 2002-11-28
IL158914A (en) 2010-04-29
HU229996B1 (hu) 2015-04-28

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