RU2269540C2 - О-арилглюкозидные ингибиторы sglt2 и способ их применения - Google Patents

О-арилглюкозидные ингибиторы sglt2 и способ их применения Download PDF

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RU2269540C2
RU2269540C2 RU2002126586/04A RU2002126586A RU2269540C2 RU 2269540 C2 RU2269540 C2 RU 2269540C2 RU 2002126586/04 A RU2002126586/04 A RU 2002126586/04A RU 2002126586 A RU2002126586 A RU 2002126586A RU 2269540 C2 RU2269540 C2 RU 2269540C2
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formula
compounds
compound according
hydrogen
alkyl
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RU2002126586A (ru
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Уиль м Н. УОШБАРН (US)
Уильям Н. УОШБАРН
Филип М. ШЕР (US)
Филип М. ШЕР
Ганг ВУ (US)
Ганг ВУ
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Бристол-Маерс Сквибб Компани
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12Antidiuretics, e.g. drugs for diabetes insipidus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
RU2002126586/04A 2000-03-30 2001-03-29 О-арилглюкозидные ингибиторы sglt2 и способ их применения RU2269540C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19309400P 2000-03-30 2000-03-30
US60/193,094 2000-03-30

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RU2002126586A RU2002126586A (ru) 2004-04-20
RU2269540C2 true RU2269540C2 (ru) 2006-02-10

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US (1) US6683056B2 (cg-RX-API-DMAC7.html)
EP (1) EP1268502B1 (cg-RX-API-DMAC7.html)
JP (1) JP4986202B2 (cg-RX-API-DMAC7.html)
KR (1) KR100798203B1 (cg-RX-API-DMAC7.html)
CN (1) CN1275977C (cg-RX-API-DMAC7.html)
AT (1) ATE316976T1 (cg-RX-API-DMAC7.html)
AU (2) AU2001249598B2 (cg-RX-API-DMAC7.html)
BR (1) BR0109326A (cg-RX-API-DMAC7.html)
CA (1) CA2404373A1 (cg-RX-API-DMAC7.html)
DE (1) DE60117012T2 (cg-RX-API-DMAC7.html)
ES (1) ES2258079T3 (cg-RX-API-DMAC7.html)
HU (1) HUP0301513A3 (cg-RX-API-DMAC7.html)
IL (1) IL151473A0 (cg-RX-API-DMAC7.html)
MX (1) MXPA02009522A (cg-RX-API-DMAC7.html)
NO (1) NO20024642L (cg-RX-API-DMAC7.html)
NZ (1) NZ520822A (cg-RX-API-DMAC7.html)
PL (1) PL365176A1 (cg-RX-API-DMAC7.html)
RU (1) RU2269540C2 (cg-RX-API-DMAC7.html)
WO (1) WO2001074834A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200207030B (cg-RX-API-DMAC7.html)

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RU2340622C2 (ru) * 2002-12-12 2008-12-10 Санофи-Авентис Дойчланд Гмбх Новые ароматические фторгликозидные производные, содержащие эти соединения лекарственные средства, и их применение
RU2408595C2 (ru) * 2006-04-05 2011-01-10 Астеллас Фарма Инк. Сокристаллическая форма производного с-гликозида c l-пролином
RU2489439C2 (ru) * 2007-11-30 2013-08-10 Новартис Аг Органические соединения

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