RU2251411C2 - Стабилизированная фармацевтическая композиция в лиофилизированной форме - Google Patents
Стабилизированная фармацевтическая композиция в лиофилизированной форме Download PDFInfo
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- RU2251411C2 RU2251411C2 RU2001108569/15A RU2001108569A RU2251411C2 RU 2251411 C2 RU2251411 C2 RU 2251411C2 RU 2001108569/15 A RU2001108569/15 A RU 2001108569/15A RU 2001108569 A RU2001108569 A RU 2001108569A RU 2251411 C2 RU2251411 C2 RU 2251411C2
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- compound
- substituted
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- lactose
- phenyl
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
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- A—HUMAN NECESSITIES
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
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- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/08—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
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- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| JP18771399 | 1999-07-01 | ||
| JP11/187713 | 1999-07-01 |
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| RU2001108569A RU2001108569A (ru) | 2003-02-20 |
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| RU2001108569/15A RU2251411C2 (ru) | 1999-07-01 | 2000-06-29 | Стабилизированная фармацевтическая композиция в лиофилизированной форме |
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| EP (1) | EP1107777B1 (https=) |
| JP (2) | JP3381722B2 (https=) |
| KR (1) | KR100454784B1 (https=) |
| CN (2) | CN1179748C (https=) |
| AR (1) | AR024634A1 (https=) |
| AT (1) | ATE280583T1 (https=) |
| AU (1) | AU752265B2 (https=) |
| BR (2) | BR0006823A (https=) |
| CA (1) | CA2341568C (https=) |
| CZ (1) | CZ295720B6 (https=) |
| DE (1) | DE60015279T2 (https=) |
| ES (1) | ES2225161T3 (https=) |
| HK (1) | HK1040057B (https=) |
| HU (1) | HU229089B1 (https=) |
| ID (1) | ID29468A (https=) |
| IL (2) | IL141455A0 (https=) |
| MX (1) | MXPA01000601A (https=) |
| NO (1) | NO330353B1 (https=) |
| NZ (1) | NZ510290A (https=) |
| OA (1) | OA11601A (https=) |
| PL (1) | PL200141B1 (https=) |
| PT (1) | PT1107777E (https=) |
| RU (1) | RU2251411C2 (https=) |
| TR (1) | TR200100609T1 (https=) |
| TW (1) | TWI233805B (https=) |
| WO (1) | WO2001002002A1 (https=) |
| ZA (1) | ZA200101589B (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| RU2666148C1 (ru) * | 2017-10-05 | 2018-09-06 | Общество с ограниченной ответственностью "Новые Антибиотики" | Способ получения водорастворимой лиофилизированной формы соли бис(2-тио-4,6-диоксо-1,2,3,4,5,6-гексагидропиримидин-5-ил)-(4-нитрофенил)метана |
| WO2019005829A1 (en) * | 2017-06-26 | 2019-01-03 | Wayne State University | METHODS AND COMPOSITIONS RELATING TO CANCER DEPENDENT ON HORMONE RECEPTORS |
| RU2726416C2 (ru) * | 2013-06-05 | 2020-07-14 | Ти Юниверсити Оф Бритиш Коламбиа | Антифиброгенные соединения, способы и их применение |
| RU2732129C2 (ru) * | 2014-12-05 | 2020-09-11 | Мейдзи Сейка Фарма Ко., Лтд. | Способ производства кристаллов производного диазабициклооктана и стабильного лиофилизированного препарата |
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| TWI233805B (en) * | 1999-07-01 | 2005-06-11 | Fujisawa Pharmaceutical Co | Stabilized pharmaceutical composition in lyophilized form as antifungal agent |
| ITMI20021040A1 (it) * | 2002-05-16 | 2003-11-17 | Novuspharma Spa | Composizioni farmaceutiche iniettabili di un derivato antracenedionico ad attivita' antitumorale |
| ATE528003T1 (de) | 2002-07-31 | 2011-10-15 | Senju Pharma Co | Wässrige, flüssigkeitszubereitungen und lichtstabilisierte wässrige flüssigkeitszubereitungen |
| US8877168B1 (en) | 2002-07-31 | 2014-11-04 | Senju Pharmaceuticals Co., Ltd. | Aqueous liquid preparations and light-stabilized aqueous liquid preparations |
| US7119061B2 (en) * | 2002-11-18 | 2006-10-10 | Vicuron Pharmaceuticals, Inc. | Dalbavancin compositions for treatment of bacterial infections |
| US20060074014A1 (en) * | 2002-11-18 | 2006-04-06 | Vicuron Pharmaceuticals Inc. | Dalbavancin compositions for treatment of bacterial infections |
| AU2003299561A1 (en) * | 2002-11-18 | 2004-06-15 | Vicuron Pharmaceuticals Inc. | Compositions and methods for treating bacterial infections with protein-dalbavancin complexes |
| US7612066B2 (en) | 2004-03-04 | 2009-11-03 | Eisai R&D Management Co., Ltd. | Composition containing benzamidine derivative and method for stabilizing benzamidine derivative |
| JP2007538046A (ja) * | 2004-05-19 | 2007-12-27 | ノイロサーチ アクティーゼルスカブ | 新規なアザビシクロアリール誘導体 |
| WO2006053383A1 (en) * | 2004-11-22 | 2006-05-26 | Anadis Ltd | Bioactive compositions |
| KR101307999B1 (ko) | 2004-12-01 | 2013-09-12 | 니폰 조키 세야쿠 가부시키가이샤 | 건조물 및 그 제조방법 |
| WO2007010995A1 (ja) * | 2005-07-20 | 2007-01-25 | Kyowa Medex Co., Ltd. | 生体試料中のペプチドの安定化方法 |
| CN1962852B (zh) * | 2006-11-27 | 2011-11-09 | 西北农林科技大学 | 红景天多糖在制备抗冻剂中的新用途及其产品和制备方法 |
| CN102614492B (zh) * | 2011-01-31 | 2013-12-11 | 上海天伟生物制药有限公司 | 一种含有棘白菌素类抗真菌剂米卡芬净的液体药用组合物 |
| CN102614491B (zh) * | 2011-01-31 | 2014-04-16 | 上海天伟生物制药有限公司 | 一种含有棘白菌素类抗真菌剂米卡芬净的药用组合物及其制备方法和用途 |
| NZ702063A (en) * | 2012-05-22 | 2016-11-25 | Paion Uk Ltd | Compositions comprising short-acting benzodiazepines |
| US9872906B2 (en) | 2013-03-15 | 2018-01-23 | Merck Sharp & Dohme Corp. | Ceftolozane antibiotic compositions |
| US9320740B2 (en) | 2013-03-15 | 2016-04-26 | Merck Sharp & Dohme Corp. | Ceftolozane-tazobactam pharmaceutical compositions |
| CN110279698B (zh) | 2013-03-15 | 2022-10-28 | 默沙东有限责任公司 | 头孢特咯瓒抗生素组合物 |
| CN103330933B (zh) * | 2013-04-26 | 2015-08-05 | 江苏豪森药业股份有限公司 | 含有米卡芬净或其盐的药物组合物 |
| CN103330932B (zh) * | 2013-04-26 | 2015-12-23 | 江苏豪森药业股份有限公司 | 一种米卡芬净或其盐的药物组合物 |
| EP3043797B1 (en) | 2013-09-09 | 2020-04-08 | Merck Sharp & Dohme Corp. | Treating infections with ceftolozane/tazobactam in subjects having impaired renal function |
| US20150094293A1 (en) | 2013-09-27 | 2015-04-02 | Calixa Therapeutics, Inc. | Solid forms of ceftolozane |
| KR101611349B1 (ko) | 2014-04-14 | 2016-04-12 | 신우철 | 안정성이 개선된 밀크씨슬 엑스의 제형 |
| EP3150621A4 (en) * | 2014-05-29 | 2017-12-27 | Shanghai Techwell Biopharmaceutical Co., Ltd | Composition of cyclic peptide compound, preparation method for same, and uses thereof |
| ES2777942T3 (es) * | 2014-12-31 | 2022-04-22 | Galenicum Health S L U | Composiciones farmacéuticas estables que comprenden micafungina |
| PL3058958T3 (pl) | 2015-02-23 | 2019-02-28 | Selectchemie Ag | Kompozycja anidulafunginy |
| WO2018112330A1 (en) | 2016-12-16 | 2018-06-21 | Baxter International Inc. | Micafungin compositions |
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- 2000-06-29 PT PT00940916T patent/PT1107777E/pt unknown
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| RU2726416C2 (ru) * | 2013-06-05 | 2020-07-14 | Ти Юниверсити Оф Бритиш Коламбиа | Антифиброгенные соединения, способы и их применение |
| RU2732129C2 (ru) * | 2014-12-05 | 2020-09-11 | Мейдзи Сейка Фарма Ко., Лтд. | Способ производства кристаллов производного диазабициклооктана и стабильного лиофилизированного препарата |
| WO2019005829A1 (en) * | 2017-06-26 | 2019-01-03 | Wayne State University | METHODS AND COMPOSITIONS RELATING TO CANCER DEPENDENT ON HORMONE RECEPTORS |
| US11185527B2 (en) | 2017-06-26 | 2021-11-30 | Wayne State University | Methods and compositions relating to steroid hormone receptor-dependent cancers |
| RU2666148C1 (ru) * | 2017-10-05 | 2018-09-06 | Общество с ограниченной ответственностью "Новые Антибиотики" | Способ получения водорастворимой лиофилизированной формы соли бис(2-тио-4,6-диоксо-1,2,3,4,5,6-гексагидропиримидин-5-ил)-(4-нитрофенил)метана |
| WO2019070169A1 (ru) * | 2017-10-05 | 2019-04-11 | Виктор Вениаминович ТЕЦ | Способ получения лиофилизированной формы (бис(2-тио-4,6-диоксо-1,2,3,4,5,6-гексагидропиримидин-5-ил)-(4-нитрофенил)метана) и полученная лиофилизированная форма |
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