RU2203046C2 - Способ изготовления таблеток флурбипрофена - Google Patents

Способ изготовления таблеток флурбипрофена Download PDF

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Publication number
RU2203046C2
RU2203046C2 RU99126868/14A RU99126868A RU2203046C2 RU 2203046 C2 RU2203046 C2 RU 2203046C2 RU 99126868/14 A RU99126868/14 A RU 99126868/14A RU 99126868 A RU99126868 A RU 99126868A RU 2203046 C2 RU2203046 C2 RU 2203046C2
Authority
RU
Russia
Prior art keywords
tablet
flurbiprofen
mixture
tablets
granules
Prior art date
Application number
RU99126868/14A
Other languages
English (en)
Russian (ru)
Other versions
RU99126868A (ru
Inventor
Эндрю ДЭЙ (GB)
Эндрю ДЭЙ
Хюв Лин ДЖОУНС (GB)
Хюв Лин ДЖОУНС
Карл Саймон СМИТ (GB)
Карл Саймон СМИТ
Original Assignee
Дзе Бутс Компани ПЛС
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Дзе Бутс Компани ПЛС filed Critical Дзе Бутс Компани ПЛС
Publication of RU99126868A publication Critical patent/RU99126868A/ru
Application granted granted Critical
Publication of RU2203046C2 publication Critical patent/RU2203046C2/ru

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Pulmonology (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU99126868/14A 1997-05-22 1998-05-20 Способ изготовления таблеток флурбипрофена RU2203046C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9710521.7A GB9710521D0 (en) 1997-05-22 1997-05-22 Process
GB9710521.7 1997-05-22

Publications (2)

Publication Number Publication Date
RU99126868A RU99126868A (ru) 2001-08-27
RU2203046C2 true RU2203046C2 (ru) 2003-04-27

Family

ID=10812840

Family Applications (1)

Application Number Title Priority Date Filing Date
RU99126868/14A RU2203046C2 (ru) 1997-05-22 1998-05-20 Способ изготовления таблеток флурбипрофена

Country Status (31)

Country Link
US (1) US6194003B1 (https=)
EP (1) EP0983059B1 (https=)
JP (1) JP2001527567A (https=)
KR (1) KR20010012739A (https=)
CN (1) CN1154480C (https=)
AR (1) AR015812A1 (https=)
AT (1) ATE245021T1 (https=)
AU (1) AU725760B2 (https=)
BG (1) BG103881A (https=)
BR (1) BR9809651A (https=)
CA (1) CA2290830C (https=)
CZ (1) CZ290816B6 (https=)
DE (1) DE69816440T2 (https=)
DK (1) DK0983059T3 (https=)
ES (1) ES2202871T3 (https=)
GB (1) GB9710521D0 (https=)
HU (1) HU224954B1 (https=)
ID (1) ID22949A (https=)
IL (1) IL132999A0 (https=)
IN (1) IN187837B (https=)
MY (1) MY118410A (https=)
NO (1) NO995681L (https=)
NZ (1) NZ500664A (https=)
PL (1) PL190947B1 (https=)
PT (1) PT983059E (https=)
RU (1) RU2203046C2 (https=)
SK (1) SK283701B6 (https=)
TR (1) TR199902725T2 (https=)
UA (1) UA53714C2 (https=)
WO (1) WO1998052539A1 (https=)
ZA (1) ZA984260B (https=)

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DK1235558T3 (da) 1999-12-09 2006-10-09 Reckitt Benckiser Healthcare Sammenpresset tabletsammensætning, der omfatter et NSAID
AU5702201A (en) * 2000-04-13 2001-10-30 Mayo Foundation Abeta<sub>42</sub> lowering agents
JP4886107B2 (ja) * 2000-10-13 2012-02-29 サンスター株式会社 歯周病予防用口腔内溶解錠
WO2004071431A2 (en) * 2003-02-05 2004-08-26 Myriad Genetics, Inc. Method and composition for treating neurodegenerative disorders
KR20060040676A (ko) * 2003-07-11 2006-05-10 미리어드 제네틱스, 인크. 알츠하이머병을 치료하기 위한 약제학적 방법, 투약 방법및 제형
FR2865648B1 (fr) * 2004-02-03 2006-06-30 Philippe Perovitch Procede de diffusion de molecules insolubles en milieu aqueux et composition mettant en oeuvre ce procede
WO2006001877A2 (en) * 2004-04-13 2006-01-05 Myriad Genetics, Inc. Combination treatment for neurodegenerative disorders comprising r-flurbiprofen
AU2005241023A1 (en) * 2004-04-29 2005-11-17 Keystone Retaining Wall Systems, Inc. Veneers for walls, retaining walls and the like
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020853A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
AU2006211023B2 (en) 2005-02-03 2012-05-24 Takeda Nycomed As Fast wet-massing method for the preparation of calcium-containing compositions
GB2423710A (en) 2005-03-01 2006-09-06 Boots Healthcare Int Ltd Lozenge production process
KR20080039876A (ko) * 2005-07-22 2008-05-07 미리어드 제네틱스, 인크. 높은 약물 충진 제형 및 투여형
CA2620219A1 (en) * 2005-11-02 2007-05-18 Teikoku Pharma Usa, Inc. Organoleptically acceptable ibuprofen oral dosage formulations, methods of making and using the same
EP2046119A2 (en) * 2006-07-07 2009-04-15 Myriad Genetics, Inc. Treatment of psychiatric disorders
WO2009014960A1 (en) * 2007-07-23 2009-01-29 Teikoku Pharma Usa, Inc. Organoleptically acceptable indole serotonin receptor agonist oral dosage formulations and methods of using the same
AU2009284011B2 (en) * 2008-08-22 2013-12-12 Reckitt Benckiser Healthcare (Uk) Limited Sore throat compositions
IT1397132B1 (it) 2009-12-01 2013-01-04 Alfa Wassermann Spa Composizioni comprendenti antiinfiammatori non steroidei.
IT1406107B1 (it) * 2010-12-13 2014-02-14 Alfa Wassermann Spa Composizioni solide comprendenti antiinfiammatori non steroidei, processi per la loro preparazione e loro uso.
SMT202100228T1 (it) 2011-04-29 2021-05-07 Moberg Pharma Ab Composizioni farmaceutiche comprendenti un anestetico locale come bupivacaina per somministrazione locale alla bocca o alla gola
EP2609911A1 (en) * 2011-12-29 2013-07-03 Sanovel Ilac Sanayi ve Ticaret A.S. A novel process for preparing orally disintegrating flurbiprofen formulations
FR2997856B1 (fr) * 2012-11-14 2015-04-24 Pf Medicament Pastille medicamenteuse a base d'ibuprofene sodique dihydrate
US20180228832A1 (en) * 2015-08-18 2018-08-16 Pharma Seeds Create, Llc Stomatological composition containing nsaid or heparin compound
WO2020013781A2 (en) * 2018-03-27 2020-01-16 Pisak Mehmet Nevzat Synergistic effect of flurbiprofen and a gastro protective agent for the treatment of pain and inflammation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302394A (en) * 1992-07-14 1994-04-12 Mcneil-Ppc, Inc. Dextromethorphan continuous lozenge manufacturing process
RU2026670C1 (ru) * 1988-10-05 1995-01-20 Дзе Апджон Компани Способ получения тонкодисперсного твердого фармацевтического вещества
EP0753296A2 (en) * 1995-06-13 1997-01-15 American Home Products Corporation Oral formulations of S(+)-ibuprofen
RU2079505C1 (ru) * 1991-02-01 1997-05-20 Иституто Джентили С.п.А. N-ациламино-1-гидроксиалкилиден-1,1-бисфосфоновые кислоты и способ их получения

Family Cites Families (6)

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US4389393A (en) * 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
US4666716A (en) * 1984-09-04 1987-05-19 Richardson-Vicks Inc. Antidiarrheal compositions and use thereof
IT1243342B (it) * 1990-07-13 1994-06-10 Farcon Ag Composizioni farmaceutiche orali liquide ad attivita' antiinfiammatoria
US5458879A (en) * 1994-03-03 1995-10-17 The Procter & Gamble Company Oral vehicle compositions
US5614207A (en) * 1995-06-30 1997-03-25 Mcneil-Ppc, Inc. Dry mouth lozenge
GB9523833D0 (en) * 1995-11-22 1996-01-24 Boots Co Plc Medical treatment

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2026670C1 (ru) * 1988-10-05 1995-01-20 Дзе Апджон Компани Способ получения тонкодисперсного твердого фармацевтического вещества
RU2079505C1 (ru) * 1991-02-01 1997-05-20 Иституто Джентили С.п.А. N-ациламино-1-гидроксиалкилиден-1,1-бисфосфоновые кислоты и способ их получения
US5302394A (en) * 1992-07-14 1994-04-12 Mcneil-Ppc, Inc. Dextromethorphan continuous lozenge manufacturing process
EP0753296A2 (en) * 1995-06-13 1997-01-15 American Home Products Corporation Oral formulations of S(+)-ibuprofen

Also Published As

Publication number Publication date
BR9809651A (pt) 2000-07-11
JP2001527567A (ja) 2001-12-25
WO1998052539A1 (en) 1998-11-26
US6194003B1 (en) 2001-02-27
CN1255848A (zh) 2000-06-07
MY118410A (en) 2004-10-30
NO995681D0 (no) 1999-11-19
SK283701B6 (sk) 2003-12-02
HUP0002121A3 (en) 2001-04-28
EP0983059A1 (en) 2000-03-08
CA2290830C (en) 2006-07-11
AU725760B2 (en) 2000-10-19
GB9710521D0 (en) 1997-07-16
IN187837B (https=) 2002-06-29
PL190947B1 (pl) 2006-02-28
ES2202871T3 (es) 2004-04-01
AU7916598A (en) 1998-12-11
EP0983059B1 (en) 2003-07-16
CZ290816B6 (cs) 2002-10-16
DE69816440T2 (de) 2004-05-13
SK158899A3 (en) 2000-05-16
AR015812A1 (es) 2001-05-30
TR199902725T2 (xx) 2000-02-21
ZA984260B (en) 1999-02-20
CN1154480C (zh) 2004-06-23
PT983059E (pt) 2003-11-28
CA2290830A1 (en) 1998-11-26
NZ500664A (en) 2001-01-26
IL132999A0 (en) 2001-03-19
DK0983059T3 (da) 2003-11-03
UA53714C2 (uk) 2003-02-17
DE69816440D1 (de) 2003-08-21
KR20010012739A (ko) 2001-02-26
ATE245021T1 (de) 2003-08-15
HU224954B1 (en) 2006-04-28
PL336624A1 (en) 2000-07-03
CZ412099A3 (cs) 2000-02-16
NO995681L (no) 1999-11-19
HUP0002121A2 (hu) 2000-12-28
ID22949A (id) 1999-12-16
BG103881A (bg) 2000-05-31

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Legal Events

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PC4A Invention patent assignment

Effective date: 20070328

PC41 Official registration of the transfer of exclusive right

Effective date: 20070609

MM4A The patent is invalid due to non-payment of fees

Effective date: 20170521