BG103881A - Метод за получаване на флурбипрофенови пастили - Google Patents

Метод за получаване на флурбипрофенови пастили

Info

Publication number
BG103881A
BG103881A BG103881A BG10388199A BG103881A BG 103881 A BG103881 A BG 103881A BG 103881 A BG103881 A BG 103881A BG 10388199 A BG10388199 A BG 10388199A BG 103881 A BG103881 A BG 103881A
Authority
BG
Bulgaria
Prior art keywords
pastills
preparation
mixture
elurbiprophene
pastill
Prior art date
Application number
BG103881A
Other languages
English (en)
Inventor
Andrew Day
Huw Jones
Carl Smith
Original Assignee
The Boots Company Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Boots Company Plc filed Critical The Boots Company Plc
Publication of BG103881A publication Critical patent/BG103881A/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Методът за получаване на фармацевтични пастилообразни форми включва следните етапи: гранулиране на смес от флурбипрофен и структурообразуващо средство с разтвор на свързващо средство в полярен разтворител до образуване на гранули; стопяване на образуващия пастили състав; смесване на гранулите със стопения състав, образуващ пастили, и формоване на получената смес в пастили. Всяка пастила съдържа лечебноефективно количество от флурбипрофен.
BG103881A 1997-05-22 1999-11-15 Метод за получаване на флурбипрофенови пастили BG103881A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9710521.7A GB9710521D0 (en) 1997-05-22 1997-05-22 Process
PCT/EP1998/003167 WO1998052539A1 (en) 1997-05-22 1998-05-20 Process for making flurbiprofen lozenges

Publications (1)

Publication Number Publication Date
BG103881A true BG103881A (bg) 2000-05-31

Family

ID=10812840

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103881A BG103881A (bg) 1997-05-22 1999-11-15 Метод за получаване на флурбипрофенови пастили

Country Status (31)

Country Link
US (1) US6194003B1 (bg)
EP (1) EP0983059B1 (bg)
JP (1) JP2001527567A (bg)
KR (1) KR20010012739A (bg)
CN (1) CN1154480C (bg)
AR (1) AR015812A1 (bg)
AT (1) ATE245021T1 (bg)
AU (1) AU725760B2 (bg)
BG (1) BG103881A (bg)
BR (1) BR9809651A (bg)
CA (1) CA2290830C (bg)
CZ (1) CZ290816B6 (bg)
DE (1) DE69816440T2 (bg)
DK (1) DK0983059T3 (bg)
ES (1) ES2202871T3 (bg)
GB (1) GB9710521D0 (bg)
HU (1) HU224954B1 (bg)
ID (1) ID22949A (bg)
IL (1) IL132999A0 (bg)
IN (1) IN187837B (bg)
MY (1) MY118410A (bg)
NO (1) NO995681L (bg)
NZ (1) NZ500664A (bg)
PL (1) PL190947B1 (bg)
PT (1) PT983059E (bg)
RU (1) RU2203046C2 (bg)
SK (1) SK283701B6 (bg)
TR (1) TR199902725T2 (bg)
UA (1) UA53714C2 (bg)
WO (1) WO1998052539A1 (bg)
ZA (1) ZA984260B (bg)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK285706B6 (sk) 1999-12-09 2007-06-07 Reckitt Benckiser Healthcare (Uk) Limited Lisovaná tabletová kompozícia, spôsob jej prípravy a jej použitie
AU2001257022B2 (en) * 2000-04-13 2005-02-03 Mayo Foundation For Medical Education And Research Abeta 42 lowering agents
JP4886107B2 (ja) * 2000-10-13 2012-02-29 サンスター株式会社 歯周病予防用口腔内溶解錠
EP1603548A4 (en) * 2003-02-05 2007-10-10 Myriad Genetics Inc COMPOSITION AND METHOD FOR TREATING NEURODEGENERATIVE DISORDERS
KR20060040676A (ko) * 2003-07-11 2006-05-10 미리어드 제네틱스, 인크. 알츠하이머병을 치료하기 위한 약제학적 방법, 투약 방법및 제형
FR2865648B1 (fr) * 2004-02-03 2006-06-30 Philippe Perovitch Procede de diffusion de molecules insolubles en milieu aqueux et composition mettant en oeuvre ce procede
US20070293538A1 (en) * 2004-04-13 2007-12-20 Myriad Genetics, Incorporated Pharmaceutical Composition And Methods For Treating Neurodegenerative Disorders
CN1946906A (zh) * 2004-04-29 2007-04-11 吉斯通护岸系统股份有限公司 用于墙、护墙和类似物的饰面
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020853A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
UA88943C2 (ru) 2005-02-03 2009-12-10 Нікомед Фарма Ас Быстрый способ влажного гранулирования для получения композиций, которые содержат кальций
GB2423710A (en) 2005-03-01 2006-09-06 Boots Healthcare Int Ltd Lozenge production process
JP2009502807A (ja) * 2005-07-22 2009-01-29 ミリアド ジェネティクス， インコーポレイテッド 薬剤含有率の高い製剤および投与量形態
EP1942877A4 (en) * 2005-11-02 2011-09-14 Teikoku Pharma Usa Inc ORGANOLEPTICALLY ACCEPTABLE ORAL DOSAGE FORMS OF IBUPROFEN, MANUFACTURING METHOD AND APPLICATION
WO2008006099A2 (en) * 2006-07-07 2008-01-10 Myriad Genetics, Inc. Treatment of psychiatric disorders
BRPI0809430A2 (pt) * 2007-07-23 2014-09-09 Teikoku Pharma Usa Inc Formulações de dosagem oral, organolepticamente aceitáveis, de um agonista indol do receptor de cerotonina e métodos de utilização das mesmas
MY155652A (en) * 2008-08-22 2015-11-13 Reckitt Benckiser Healthcare Improvements in or relating to compositions
IT1397132B1 (it) 2009-12-01 2013-01-04 Alfa Wassermann Spa Composizioni comprendenti antiinfiammatori non steroidei.
IT1406107B1 (it) * 2010-12-13 2014-02-14 Alfa Wassermann Spa Composizioni solide comprendenti antiinfiammatori non steroidei, processi per la loro preparazione e loro uso.
RS55372B1 (sr) 2011-04-29 2017-03-31 Moberg Pharma Ab Farmaceutske kompozicije koje sadrže lokalni anestetik kao što je bupivakain, za lokalnu administraciju u ustima ili grlu
EP2609911A1 (en) * 2011-12-29 2013-07-03 Sanovel Ilac Sanayi ve Ticaret A.S. A novel process for preparing orally disintegrating flurbiprofen formulations
FR2997856B1 (fr) * 2012-11-14 2015-04-24 Pf Medicament Pastille medicamenteuse a base d'ibuprofene sodique dihydrate
US20180228832A1 (en) * 2015-08-18 2018-08-16 Pharma Seeds Create, Llc Stomatological composition containing nsaid or heparin compound
WO2020013781A2 (en) * 2018-03-27 2020-01-16 Pisak Mehmet Nevzat Synergistic effect of flurbiprofen and a gastro protective agent for the treatment of pain and inflammation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4389393A (en) * 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
US4666716A (en) * 1984-09-04 1987-05-19 Richardson-Vicks Inc. Antidiarrheal compositions and use thereof
IT1243342B (it) * 1990-07-13 1994-06-10 Farcon Ag Composizioni farmaceutiche orali liquide ad attivita' antiinfiammatoria
US5302394A (en) 1992-07-14 1994-04-12 Mcneil-Ppc, Inc. Dextromethorphan continuous lozenge manufacturing process
US5458879A (en) * 1994-03-03 1995-10-17 The Procter & Gamble Company Oral vehicle compositions
TW442287B (en) * 1995-06-13 2001-06-23 American Home Produits Corp Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac)
US5614207A (en) * 1995-06-30 1997-03-25 Mcneil-Ppc, Inc. Dry mouth lozenge
GB9523833D0 (en) * 1995-11-22 1996-01-24 Boots Co Plc Medical treatment

Also Published As

Publication number Publication date
IN187837B (bg) 2002-06-29
MY118410A (en) 2004-10-30
GB9710521D0 (en) 1997-07-16
IL132999A0 (en) 2001-03-19
UA53714C2 (uk) 2003-02-17
CN1255848A (zh) 2000-06-07
AU725760B2 (en) 2000-10-19
KR20010012739A (ko) 2001-02-26
ATE245021T1 (de) 2003-08-15
CA2290830A1 (en) 1998-11-26
ZA984260B (en) 1999-02-20
CZ290816B6 (cs) 2002-10-16
CZ412099A3 (cs) 2000-02-16
NZ500664A (en) 2001-01-26
PL336624A1 (en) 2000-07-03
DE69816440T2 (de) 2004-05-13
PL190947B1 (pl) 2006-02-28
SK158899A3 (en) 2000-05-16
CA2290830C (en) 2006-07-11
WO1998052539A1 (en) 1998-11-26
RU2203046C2 (ru) 2003-04-27
DE69816440D1 (de) 2003-08-21
HUP0002121A2 (hu) 2000-12-28
EP0983059A1 (en) 2000-03-08
DK0983059T3 (da) 2003-11-03
JP2001527567A (ja) 2001-12-25
TR199902725T2 (xx) 2000-02-21
SK283701B6 (sk) 2003-12-02
ES2202871T3 (es) 2004-04-01
PT983059E (pt) 2003-11-28
US6194003B1 (en) 2001-02-27
AR015812A1 (es) 2001-05-30
BR9809651A (pt) 2000-07-11
NO995681D0 (no) 1999-11-19
HUP0002121A3 (en) 2001-04-28
AU7916598A (en) 1998-12-11
EP0983059B1 (en) 2003-07-16
ID22949A (id) 1999-12-16
CN1154480C (zh) 2004-06-23
NO995681L (no) 1999-11-19
HU224954B1 (en) 2006-04-28

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