NZ500664A - Process for making flurbiprofen lozenges by granulating flubiprofen with a bulking agent (selected from calcium carbonate, tricalcium phosphate or microcrystalline cellulose) - Google Patents

Process for making flurbiprofen lozenges by granulating flubiprofen with a bulking agent (selected from calcium carbonate, tricalcium phosphate or microcrystalline cellulose)

Info

Publication number
NZ500664A
NZ500664A NZ500664A NZ50066498A NZ500664A NZ 500664 A NZ500664 A NZ 500664A NZ 500664 A NZ500664 A NZ 500664A NZ 50066498 A NZ50066498 A NZ 50066498A NZ 500664 A NZ500664 A NZ 500664A
Authority
NZ
New Zealand
Prior art keywords
granulating
calcium carbonate
microcrystalline cellulose
tricalcium phosphate
bulking agent
Prior art date
Application number
NZ500664A
Other languages
English (en)
Inventor
Andrew Day
Huw Lyn Jones
Carl Simon Smith
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co Plc filed Critical Boots Co Plc
Publication of NZ500664A publication Critical patent/NZ500664A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Pulmonology (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NZ500664A 1997-05-22 1998-05-20 Process for making flurbiprofen lozenges by granulating flubiprofen with a bulking agent (selected from calcium carbonate, tricalcium phosphate or microcrystalline cellulose) NZ500664A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9710521.7A GB9710521D0 (en) 1997-05-22 1997-05-22 Process
PCT/EP1998/003167 WO1998052539A1 (en) 1997-05-22 1998-05-20 Process for making flurbiprofen lozenges

Publications (1)

Publication Number Publication Date
NZ500664A true NZ500664A (en) 2001-01-26

Family

ID=10812840

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ500664A NZ500664A (en) 1997-05-22 1998-05-20 Process for making flurbiprofen lozenges by granulating flubiprofen with a bulking agent (selected from calcium carbonate, tricalcium phosphate or microcrystalline cellulose)

Country Status (31)

Country Link
US (1) US6194003B1 (https=)
EP (1) EP0983059B1 (https=)
JP (1) JP2001527567A (https=)
KR (1) KR20010012739A (https=)
CN (1) CN1154480C (https=)
AR (1) AR015812A1 (https=)
AT (1) ATE245021T1 (https=)
AU (1) AU725760B2 (https=)
BG (1) BG103881A (https=)
BR (1) BR9809651A (https=)
CA (1) CA2290830C (https=)
CZ (1) CZ290816B6 (https=)
DE (1) DE69816440T2 (https=)
DK (1) DK0983059T3 (https=)
ES (1) ES2202871T3 (https=)
GB (1) GB9710521D0 (https=)
HU (1) HU224954B1 (https=)
ID (1) ID22949A (https=)
IL (1) IL132999A0 (https=)
IN (1) IN187837B (https=)
MY (1) MY118410A (https=)
NO (1) NO995681L (https=)
NZ (1) NZ500664A (https=)
PL (1) PL190947B1 (https=)
PT (1) PT983059E (https=)
RU (1) RU2203046C2 (https=)
SK (1) SK283701B6 (https=)
TR (1) TR199902725T2 (https=)
UA (1) UA53714C2 (https=)
WO (1) WO1998052539A1 (https=)
ZA (1) ZA984260B (https=)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1235558T3 (da) 1999-12-09 2006-10-09 Reckitt Benckiser Healthcare Sammenpresset tabletsammensætning, der omfatter et NSAID
AU5702201A (en) * 2000-04-13 2001-10-30 Mayo Foundation Abeta<sub>42</sub> lowering agents
JP4886107B2 (ja) * 2000-10-13 2012-02-29 サンスター株式会社 歯周病予防用口腔内溶解錠
WO2004071431A2 (en) * 2003-02-05 2004-08-26 Myriad Genetics, Inc. Method and composition for treating neurodegenerative disorders
KR20060040676A (ko) * 2003-07-11 2006-05-10 미리어드 제네틱스, 인크. 알츠하이머병을 치료하기 위한 약제학적 방법, 투약 방법및 제형
FR2865648B1 (fr) * 2004-02-03 2006-06-30 Philippe Perovitch Procede de diffusion de molecules insolubles en milieu aqueux et composition mettant en oeuvre ce procede
WO2006001877A2 (en) * 2004-04-13 2006-01-05 Myriad Genetics, Inc. Combination treatment for neurodegenerative disorders comprising r-flurbiprofen
AU2005241023A1 (en) * 2004-04-29 2005-11-17 Keystone Retaining Wall Systems, Inc. Veneers for walls, retaining walls and the like
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020853A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
AU2006211023B2 (en) 2005-02-03 2012-05-24 Takeda Nycomed As Fast wet-massing method for the preparation of calcium-containing compositions
GB2423710A (en) 2005-03-01 2006-09-06 Boots Healthcare Int Ltd Lozenge production process
KR20080039876A (ko) * 2005-07-22 2008-05-07 미리어드 제네틱스, 인크. 높은 약물 충진 제형 및 투여형
CA2620219A1 (en) * 2005-11-02 2007-05-18 Teikoku Pharma Usa, Inc. Organoleptically acceptable ibuprofen oral dosage formulations, methods of making and using the same
EP2046119A2 (en) * 2006-07-07 2009-04-15 Myriad Genetics, Inc. Treatment of psychiatric disorders
WO2009014960A1 (en) * 2007-07-23 2009-01-29 Teikoku Pharma Usa, Inc. Organoleptically acceptable indole serotonin receptor agonist oral dosage formulations and methods of using the same
AU2009284011B2 (en) * 2008-08-22 2013-12-12 Reckitt Benckiser Healthcare (Uk) Limited Sore throat compositions
IT1397132B1 (it) 2009-12-01 2013-01-04 Alfa Wassermann Spa Composizioni comprendenti antiinfiammatori non steroidei.
IT1406107B1 (it) * 2010-12-13 2014-02-14 Alfa Wassermann Spa Composizioni solide comprendenti antiinfiammatori non steroidei, processi per la loro preparazione e loro uso.
SMT202100228T1 (it) 2011-04-29 2021-05-07 Moberg Pharma Ab Composizioni farmaceutiche comprendenti un anestetico locale come bupivacaina per somministrazione locale alla bocca o alla gola
EP2609911A1 (en) * 2011-12-29 2013-07-03 Sanovel Ilac Sanayi ve Ticaret A.S. A novel process for preparing orally disintegrating flurbiprofen formulations
FR2997856B1 (fr) * 2012-11-14 2015-04-24 Pf Medicament Pastille medicamenteuse a base d'ibuprofene sodique dihydrate
US20180228832A1 (en) * 2015-08-18 2018-08-16 Pharma Seeds Create, Llc Stomatological composition containing nsaid or heparin compound
WO2020013781A2 (en) * 2018-03-27 2020-01-16 Pisak Mehmet Nevzat Synergistic effect of flurbiprofen and a gastro protective agent for the treatment of pain and inflammation

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4389393A (en) * 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
US4666716A (en) * 1984-09-04 1987-05-19 Richardson-Vicks Inc. Antidiarrheal compositions and use thereof
RU2026670C1 (ru) * 1988-10-05 1995-01-20 Дзе Апджон Компани Способ получения тонкодисперсного твердого фармацевтического вещества
IT1243342B (it) * 1990-07-13 1994-06-10 Farcon Ag Composizioni farmaceutiche orali liquide ad attivita' antiinfiammatoria
IT1244698B (it) * 1991-02-01 1994-08-08 Gentili Ist Spa Acidi aril-o arilalchil-acil ammino-alchil-idrossidifosfonici, procedimento per la loro preparazione e loro uso in terapia osteo-articolare e dei tessuti connettori in generale
US5302394A (en) * 1992-07-14 1994-04-12 Mcneil-Ppc, Inc. Dextromethorphan continuous lozenge manufacturing process
US5458879A (en) * 1994-03-03 1995-10-17 The Procter & Gamble Company Oral vehicle compositions
TW442287B (en) * 1995-06-13 2001-06-23 American Home Produits Corp Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac)
US5614207A (en) * 1995-06-30 1997-03-25 Mcneil-Ppc, Inc. Dry mouth lozenge
GB9523833D0 (en) * 1995-11-22 1996-01-24 Boots Co Plc Medical treatment

Also Published As

Publication number Publication date
RU2203046C2 (ru) 2003-04-27
BR9809651A (pt) 2000-07-11
JP2001527567A (ja) 2001-12-25
WO1998052539A1 (en) 1998-11-26
US6194003B1 (en) 2001-02-27
CN1255848A (zh) 2000-06-07
MY118410A (en) 2004-10-30
NO995681D0 (no) 1999-11-19
SK283701B6 (sk) 2003-12-02
HUP0002121A3 (en) 2001-04-28
EP0983059A1 (en) 2000-03-08
CA2290830C (en) 2006-07-11
AU725760B2 (en) 2000-10-19
GB9710521D0 (en) 1997-07-16
IN187837B (https=) 2002-06-29
PL190947B1 (pl) 2006-02-28
ES2202871T3 (es) 2004-04-01
AU7916598A (en) 1998-12-11
EP0983059B1 (en) 2003-07-16
CZ290816B6 (cs) 2002-10-16
DE69816440T2 (de) 2004-05-13
SK158899A3 (en) 2000-05-16
AR015812A1 (es) 2001-05-30
TR199902725T2 (xx) 2000-02-21
ZA984260B (en) 1999-02-20
CN1154480C (zh) 2004-06-23
PT983059E (pt) 2003-11-28
CA2290830A1 (en) 1998-11-26
IL132999A0 (en) 2001-03-19
DK0983059T3 (da) 2003-11-03
UA53714C2 (uk) 2003-02-17
DE69816440D1 (de) 2003-08-21
KR20010012739A (ko) 2001-02-26
ATE245021T1 (de) 2003-08-15
HU224954B1 (en) 2006-04-28
PL336624A1 (en) 2000-07-03
CZ412099A3 (cs) 2000-02-16
NO995681L (no) 1999-11-19
HUP0002121A2 (hu) 2000-12-28
ID22949A (id) 1999-12-16
BG103881A (bg) 2000-05-31

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Legal Events

Date Code Title Description
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
ASS Change of ownership

Owner name: RECKITT BENCKISER HEALTHCARE (UK) LIMITED, GB

Free format text: OLD OWNER(S): RECKITT BENCKISER HEALTHCARE (UK) LIMITED; BOOTS HEALTHCARE INTERNATIONAL LIMITED

Owner name: RECKITT BENCKISER HEALTHCARE (UK) LIMITED, GB

Free format text: OLD OWNER(S): RECKITT BENCKISER HEALTHCARE (UK) LIMITED; RECKITT BENCKISER HEALTHCARE (UK) LIMITED

Owner name: RECKITT BENCKISER HEALTHCARE (UK) LIMITED, GB

Free format text: OLD OWNER(S): RECKITT BENCKISER HEALTHCARE (UK) LIMITED; THE BOOTS COMPANY PLC

Owner name: RECKITT BENCKISER HEALTHCARE (UK) LIMITED, GB

Free format text: OLD OWNER(S): BOOTS HEALTHCARE INTERNATIONAL LIMITED

RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
EXPY Patent expired