KR840000239A - 완충-아스피린 생성에 적합한 압착형성된 알카리성 조성 - Google Patents

완충-아스피린 생성에 적합한 압착형성된 알카리성 조성 Download PDF

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KR840000239A
KR840000239A KR1019820002953A KR820002953A KR840000239A KR 840000239 A KR840000239 A KR 840000239A KR 1019820002953 A KR1019820002953 A KR 1019820002953A KR 820002953 A KR820002953 A KR 820002953A KR 840000239 A KR840000239 A KR 840000239A
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alkali
composition
alkali composition
compressed
magnesium
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KR1019820002953A
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KR880001933B1 (ko
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시모니안 호브셉
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이삭 쟈코브스키
브리스톨 마이어스 컴퍼니
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

내용 없음

Description

완충-아스피린 생성에 적합한 압착형성된 알카리성 조성
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (8)

  1. 산화마그네슘, 수산화마그네슘, 그리고 양자의 결합물로 이루어진 그룹에서 선택한 마그네슘옥시, 탄산칼슘, 탄산마그네슘 조성물로 이루어진 건조 혼합물을 형성해서 형성된 혼합물을 구연산과 인산이수소 나트륨을 함유하는 입화액으로 습윤시키고, 습윤된 혼합물을 과립화시키고, 그것을 압착시킴을 특징으로 하는 압착-알칼리성 조성물의 제조방법.
  2. 상기 입화액중, 구연산은 입화액 전량 무게의 1-5%을, 인산이수소 나트륨은 입화액 전량 무게의 1-5%를 함유하는, 제1항에 따르는 제조방법.
  3. 완충-아스피린을 생성하기 위해, 아스피린과 더불어 응용되는,
    (1) 상기 탄산칼슘, 탄산마그네슘, 마그네슘 옥시 조성물과 혼합물로 이루어진 그룹에서 선택된 알카리성물질의 효과있는 완충량을 가지는 압착된 알카리성분. 또는,
    (2) 상기의 산화마그네슘, 수산화마그네슘, 그리고 양자의 혼합물로 이루어진 그룹에서 선택된 마그네슘 옥시 조성분. 또는,
    (3) 전술한 알카리 조성분의 산 중화반응비를 상승하는 충분량의 구연산과 인산이 수소나트륨이 혼합된 압착 알카리 조성분으로 이루어진, 압착형성된 알카리 조성물.
  4. 전술한 알카리 조성분에서 전(全) 알카리 물질이 알카리 조성분 전체량의 약 35%-95%인, 제3항에 따르는 압착형성된 알카리 조성분.
  5. 전술한 조성분중, 알카리성 물질이 알카리 조성분 전량의 약 75%-95%인, 제4항에 따르는 압착형성된 알카리 조성분.
  6. 전술한 알카리 물질을 적어도 하나 함유하며, 압축 알카리 조성분중 여러 성분들이 알카리 조성분 전체량의 다음과 같은 범위내에 존재하는, 제3항에 따르는 압축형성된 알카리 조성분.
  7. 전술한 알카리 물질을 최소한 2가지 함유하며, 압축 알카리 조성분중의 여러 성분들이 알카리 조성분 전체량의 다음과 같은 범위내에 존재하는, 제3항에 따르는 압축형성된 알카리 조성분.
  8. 전술한 알카리 물질을 최소한 3가지 함유하며, 압축 알카리 조성분중의 여러 성분들이 알카리 조성분 전체량의 다음과 같은 범위내에 존재하는, 제3항에 따르는 압축형성된 알카리 조성분.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR8202953A 1981-07-01 1982-07-01 완충-아스피린의 생성에 적합한 압착 형성된 알카리성 조성물 및 그것의 제조방법 KR880001933B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27801181A 1981-07-01 1981-07-01
US278011 1981-07-01
US278,011 1981-07-01

Publications (2)

Publication Number Publication Date
KR840000239A true KR840000239A (ko) 1984-02-18
KR880001933B1 KR880001933B1 (ko) 1988-10-04

Family

ID=23063318

Family Applications (1)

Application Number Title Priority Date Filing Date
KR8202953A KR880001933B1 (ko) 1981-07-01 1982-07-01 완충-아스피린의 생성에 적합한 압착 형성된 알카리성 조성물 및 그것의 제조방법

Country Status (9)

Country Link
JP (1) JPS588020A (ko)
KR (1) KR880001933B1 (ko)
AU (1) AU551510B2 (ko)
BE (1) BE893729A (ko)
CA (1) CA1165242A (ko)
GR (1) GR75990B (ko)
NZ (1) NZ200695A (ko)
PH (1) PH18787A (ko)
PT (1) PT75168B (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4102629A1 (de) * 1991-01-30 1992-08-06 Bayer Ag Pharmazeutischer kaugummi mit acetylsalicylsaeure
FR2708853A1 (fr) * 1993-06-30 1995-02-17 Salsarulo Gilles Composition à base d'acide acétylsalicylique à biodisponibilité améliorée et procédé pour la produire.
US5498426A (en) * 1994-10-03 1996-03-12 The Procter & Gamble Company Liquid antacid compositions
US6077539A (en) 1996-11-12 2000-06-20 Pozen, Inc. Treatment of migraine headache
UA95093C2 (uk) * 2005-12-07 2011-07-11 Нікомед Фарма Ас Спосіб одержання кальцієвмісної сполуки
JP5663238B2 (ja) * 2009-08-31 2015-02-04 ライオン株式会社 内服固形製剤及びその製造方法

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Publication number Publication date
PT75168A (en) 1982-07-01
NZ200695A (en) 1985-02-28
KR880001933B1 (ko) 1988-10-04
PH18787A (en) 1985-09-25
JPS588020A (ja) 1983-01-18
BE893729A (fr) 1983-01-03
AU8410982A (en) 1983-01-06
CA1165242A (en) 1984-04-10
GR75990B (ko) 1984-08-03
PT75168B (en) 1985-06-28
AU551510B2 (en) 1986-05-01
JPH0244286B2 (ko) 1990-10-03

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