RU2197970C2 - Композиции и способы, предназначенные для снижения глазной гипертензии - Google Patents

Композиции и способы, предназначенные для снижения глазной гипертензии Download PDF

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Publication number
RU2197970C2
RU2197970C2 RU99121641/14A RU99121641A RU2197970C2 RU 2197970 C2 RU2197970 C2 RU 2197970C2 RU 99121641/14 A RU99121641/14 A RU 99121641/14A RU 99121641 A RU99121641 A RU 99121641A RU 2197970 C2 RU2197970 C2 RU 2197970C2
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Russia
Prior art keywords
composition
preservative
composition according
group
prostaglandins
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RU99121641/14A
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English (en)
Russian (ru)
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RU99121641A (ru
Inventor
Кеннет Уоррен РИД
Шаофэн ЮНЬ
Мэри СОУ
Реджайна Флинн ПИКОК
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Новартис Аг
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Application filed by Новартис Аг filed Critical Новартис Аг
Publication of RU99121641A publication Critical patent/RU99121641A/ru
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
RU99121641/14A 1997-03-17 1998-03-13 Композиции и способы, предназначенные для снижения глазной гипертензии RU2197970C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81922197A 1997-03-17 1997-03-17
US08/819,221 1997-03-17

Publications (2)

Publication Number Publication Date
RU99121641A RU99121641A (ru) 2001-08-20
RU2197970C2 true RU2197970C2 (ru) 2003-02-10

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ID=38729083

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Application Number Title Priority Date Filing Date
RU99121641/14A RU2197970C2 (ru) 1997-03-17 1998-03-13 Композиции и способы, предназначенные для снижения глазной гипертензии

Country Status (32)

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EP (1) EP0969846B2 (enExample)
JP (2) JP4920124B2 (enExample)
KR (1) KR100555818B1 (enExample)
CN (1) CN1236775C (enExample)
AR (2) AR002194A1 (enExample)
AT (1) ATE257385T1 (enExample)
AU (1) AU738781B2 (enExample)
BR (2) BRPI9816218B1 (enExample)
CA (1) CA2280089C (enExample)
CL (1) CL2009001870A1 (enExample)
CO (1) CO4940427A1 (enExample)
CY (1) CY2526B1 (enExample)
CZ (1) CZ299833B6 (enExample)
DE (1) DE69820997T3 (enExample)
DK (1) DK0969846T4 (enExample)
EE (1) EE04091B1 (enExample)
ES (1) ES2214706T5 (enExample)
HU (1) HU228896B1 (enExample)
ID (1) ID22389A (enExample)
IL (1) IL131041A0 (enExample)
MY (1) MY122237A (enExample)
NO (1) NO327713B1 (enExample)
NZ (1) NZ337322A (enExample)
PE (1) PE61899A1 (enExample)
PL (1) PL197509B1 (enExample)
PT (1) PT969846E (enExample)
RU (1) RU2197970C2 (enExample)
SI (1) SI0969846T2 (enExample)
TW (1) TW527187B (enExample)
UA (1) UA63938C2 (enExample)
WO (1) WO1998041208A1 (enExample)
ZA (1) ZA982188B (enExample)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2266572C1 (ru) * 2004-03-17 2005-12-20 Российский государственный медицинский университет Способ моделирования злокачественной артериальной гипертонии
RU2397776C2 (ru) * 2005-03-31 2010-08-27 Др. Герхард Манн Хем.-Фарм. Фабрик Гмбх Офтальмологический состав
RU2402316C2 (ru) * 2009-01-11 2010-10-27 Пшеничников Виталий Георгиевич Фармацевтическая антиглаукомная композиция
RU2462234C2 (ru) * 2006-03-17 2012-09-27 Джонсон Энд Джонсон Вижн Кэа, Инк. Способы стабилизации окислительно нестабильных композиций
RU2465898C2 (ru) * 2006-10-31 2012-11-10 Алькон Рисерч, Лтд. Модуляторы связывания pai-1 для лечения глазных болезней
EA019867B1 (ru) * 2007-10-08 2014-06-30 Фовея Фармасьютикалс Водные офтальмологические препараты
RU2776374C2 (ru) * 2017-12-28 2022-07-19 Сантен Фармасьютикал Ко., Лтд. Фармацевтический препарат, содержащий пиридиламиноуксусную кислоту

Families Citing this family (33)

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US6011062A (en) * 1994-12-22 2000-01-04 Alcon Laboratories, Inc. Storage-stable prostaglandin compositions
AR002194A1 (es) * 1997-03-17 1998-01-07 Sanchez Reynaldo Alemany Instrumento computarizado para el analisis del movimiento.
US6187818B1 (en) * 1998-06-17 2001-02-13 Pharmacia & Upjohn Company Prostaglandins formulation and process
JP4880808B2 (ja) * 1999-11-15 2012-02-22 久光製薬株式会社 人工涙液型点眼剤組成物
TWI290470B (en) * 1999-12-01 2007-12-01 Sankyo Co The composition for treating glaucoma
DK1321144T3 (da) * 2000-09-13 2011-03-07 Santen Pharmaceutical Co Ltd Øjendråber
WO2002045748A1 (en) * 2000-12-05 2002-06-13 Sankyo Company, Limited Ocular tension-lowering compositions for topical administration
US20020198209A1 (en) * 2001-05-03 2002-12-26 Allergan Sales Inc. Compositions having enhanced pharmacokinetic characteristics
US7074827B2 (en) * 2002-10-24 2006-07-11 Sucampo Ag (Usa) Inc. Method for treating ocular hypertension and glaucoma
ES2331890T3 (es) * 2004-03-18 2010-01-19 R-Tech Ueno, Ltd. Composicion acuosa que comprende un derivado de tiazol.
US8569367B2 (en) 2004-11-16 2013-10-29 Allergan, Inc. Ophthalmic compositions and methods for treating eyes
GB0501192D0 (en) * 2005-01-20 2005-03-02 Resolution Chemicals Ltd Stable prostaglandin-containing compositions
US7851504B2 (en) * 2005-03-16 2010-12-14 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
JP5252787B2 (ja) * 2005-08-02 2013-07-31 参天製薬株式会社 熱的に不安定な薬物の分解抑制方法
EP1916002B1 (en) * 2005-08-02 2014-03-05 Santen Pharmaceutical Co., Ltd. Method for prevention of degradation of thermally unstable substance
JP2007099647A (ja) * 2005-09-30 2007-04-19 Kobayashi Pharmaceut Co Ltd 粘膜適用組成物
US8168206B1 (en) 2005-10-06 2012-05-01 Allergan, Inc. Animal protein-free pharmaceutical compositions
JPWO2007105691A1 (ja) * 2006-03-13 2009-07-30 株式会社アールテック・ウエノ 水性組成物
JPWO2008096804A1 (ja) * 2007-02-07 2010-05-27 テイカ製薬株式会社 ラタノプロスト含有点眼剤
JP2009073788A (ja) * 2007-09-21 2009-04-09 Teika Seiyaku Kk イソプロピルウノプロストン含有眼用組成物
AU2009225931B9 (en) * 2008-03-17 2014-04-03 Novartis Ag Aqueous pharmaceutical compositions containing borate-polyol complexes
TWI544927B (zh) * 2008-03-17 2016-08-11 愛爾康研究有限公司 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物
EP2127638A1 (en) 2008-05-30 2009-12-02 Santen Pharmaceutical Co., Ltd Method and composition for treating ocular hypertension and glaucoma
US8952051B2 (en) * 2009-11-05 2015-02-10 Allergan, Inc. Ophthalmic formulations containing substituted gamma lactams and methods for use thereof
JP2014510709A (ja) * 2011-04-12 2014-05-01 株式会社アールテック・ウエノ 眼科用水性組成物
US20130029919A1 (en) 2011-07-26 2013-01-31 Allergan, Inc. Two part formulation system for opthalmic delivery
EP2567689A1 (en) 2011-09-12 2013-03-13 Visiotact Pharma Ophthtalmic compositions comprising prostaglandin F2 alpha derivatives and hyaluronic acid
US8957048B2 (en) 2011-10-06 2015-02-17 Allergan, Inc. Compositions for the treatment of dry eye
US9907826B2 (en) 2011-12-07 2018-03-06 Allergan, Inc. Efficient lipid delivery to human tear film using a salt-sensitive emulsion system
HUE057140T2 (hu) 2011-12-07 2022-04-28 Allergan Inc Hatásos lipidszállítás humán könny-filmhez sóérzékeny emulziórendszer alkalmazásával
RU2697844C9 (ru) 2014-11-25 2019-10-01 Аллерган, Инк. Стабилизированные композиции для офтальмологического применения, содержащие омега-3-кислоты
AU2019343188A1 (en) * 2018-09-21 2021-05-20 Aufbau Medical Innovations Limited Compositions and methods for glaucoma
BR112021020425A2 (pt) 2019-04-12 2021-12-14 Ecolab Usa Inc Composições de limpeza multiuso concentrada e pronta para uso, e, métodos para limpar uma superfície e de fabricação da composição de limpeza multiuso

Citations (1)

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Publication number Priority date Publication date Assignee Title
US5558876A (en) * 1995-03-29 1996-09-24 Alcon Laboratories, Inc. Topical ophthalmic acidic drug formulations

Family Cites Families (6)

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EP0458587B1 (en) * 1990-05-22 1993-07-14 R-Tech Ueno Ltd. Synergistic combination for ophthalmic use
IE920397A1 (en) * 1991-02-07 1992-08-12 Allergan Inc 2-decarboxyl-2-hydroxyalkyl-5-trans prostaglandin f¹derivatives
US5767154A (en) * 1991-02-07 1998-06-16 Allergan 5-trans-prostaglandins of the F series and their use as ocular hypotensives
JP2742333B2 (ja) * 1994-05-06 1998-04-22 アルコン ラボラトリーズ,インコーポレイテッド 眼科用組成物におけるビタミンeトコフェリル誘導体の使用
US5631287A (en) 1994-12-22 1997-05-20 Alcon Laboratories, Inc. Storage-stable prostaglandin compositions
AR002194A1 (es) * 1997-03-17 1998-01-07 Sanchez Reynaldo Alemany Instrumento computarizado para el analisis del movimiento.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5558876A (en) * 1995-03-29 1996-09-24 Alcon Laboratories, Inc. Topical ophthalmic acidic drug formulations

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
МАШКОВСКИЙ М.Д. Лекарственные средства. - М.: Медицина, 1986, ч.1, с. 218-221, ч.2, с. 523-525. *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2266572C1 (ru) * 2004-03-17 2005-12-20 Российский государственный медицинский университет Способ моделирования злокачественной артериальной гипертонии
RU2397776C2 (ru) * 2005-03-31 2010-08-27 Др. Герхард Манн Хем.-Фарм. Фабрик Гмбх Офтальмологический состав
RU2462234C2 (ru) * 2006-03-17 2012-09-27 Джонсон Энд Джонсон Вижн Кэа, Инк. Способы стабилизации окислительно нестабильных композиций
RU2465898C2 (ru) * 2006-10-31 2012-11-10 Алькон Рисерч, Лтд. Модуляторы связывания pai-1 для лечения глазных болезней
EA019867B1 (ru) * 2007-10-08 2014-06-30 Фовея Фармасьютикалс Водные офтальмологические препараты
RU2402316C2 (ru) * 2009-01-11 2010-10-27 Пшеничников Виталий Георгиевич Фармацевтическая антиглаукомная композиция
RU2776374C2 (ru) * 2017-12-28 2022-07-19 Сантен Фармасьютикал Ко., Лтд. Фармацевтический препарат, содержащий пиридиламиноуксусную кислоту

Also Published As

Publication number Publication date
CL2009001870A1 (es) 2010-01-22
DE69820997T3 (de) 2011-10-06
NZ337322A (en) 2001-05-25
BR9808016A (pt) 2000-03-08
PE61899A1 (es) 1999-06-30
SI0969846T1 (en) 2004-06-30
CY2526B1 (en) 2006-02-08
SI0969846T2 (sl) 2010-12-31
EE9900410A (et) 2000-04-17
JP2010043110A (ja) 2010-02-25
ID22389A (id) 1999-10-07
EP0969846B2 (en) 2010-08-25
KR100555818B1 (ko) 2006-03-03
ATE257385T1 (de) 2004-01-15
NO327713B1 (no) 2009-09-14
KR20000076330A (ko) 2000-12-26
CO4940427A1 (es) 2000-07-24
WO1998041208A1 (en) 1998-09-24
DK0969846T4 (da) 2010-12-20
JP4920124B2 (ja) 2012-04-18
PL197509B1 (pl) 2008-04-30
CA2280089C (en) 2009-03-03
HU228896B1 (en) 2013-06-28
HK1026841A1 (en) 2000-12-29
BRPI9816218B1 (pt) 2016-04-12
JP2001515502A (ja) 2001-09-18
DE69820997T2 (de) 2004-12-09
TW527187B (en) 2003-04-11
DE69820997D1 (de) 2004-02-12
HUP0002194A2 (hu) 2000-12-28
ES2214706T5 (es) 2011-02-02
HUP0002194A3 (en) 2012-08-28
EP0969846A1 (en) 2000-01-12
CZ299833B6 (cs) 2008-12-10
AU738781B2 (en) 2001-09-27
ZA982188B (en) 1998-09-17
AU7035398A (en) 1998-10-12
MY122237A (en) 2006-04-29
EP0969846B1 (en) 2004-01-07
NO994481D0 (no) 1999-09-16
AR002194A1 (es) 1998-01-07
CN1249687A (zh) 2000-04-05
IL131041A0 (en) 2001-01-28
ES2214706T3 (es) 2004-09-16
NO994481L (no) 1999-09-16
PL335168A1 (en) 2000-04-10
PT969846E (pt) 2004-05-31
CN1236775C (zh) 2006-01-18
AR011192A1 (es) 2000-08-02
CA2280089A1 (en) 1998-09-24
UA63938C2 (uk) 2004-02-16
DK0969846T3 (da) 2004-04-13
EE04091B1 (et) 2003-08-15
CZ325799A3 (cs) 2000-01-12

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Effective date: 20150314