BR9808016A - Composições e métodos para redução da hipertensão ocular - Google Patents

Composições e métodos para redução da hipertensão ocular

Info

Publication number
BR9808016A
BR9808016A BR9808016-4A BR9808016A BR9808016A BR 9808016 A BR9808016 A BR 9808016A BR 9808016 A BR9808016 A BR 9808016A BR 9808016 A BR9808016 A BR 9808016A
Authority
BR
Brazil
Prior art keywords
compositions
prostaglandin
methods
ocular hypertension
reducing
Prior art date
Application number
BR9808016-4A
Other languages
English (en)
Inventor
Kenneth Warren Reed
Shau-Fong Yen
Mary Sou
Regina Flinn Peacock
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38729083&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9808016(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Priority to BRPI9816218A priority Critical patent/BRPI9816218B1/pt
Publication of BR9808016A publication Critical patent/BR9808016A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

Patente de Invenção: <B>"COMPOSIçõES E MéTODOS PARA REDUçãO DA HIPERTENSãO OCULAR"<D>. Composição oftálmica aperfeiçoada, incluindo agentes ativos de prostaglandina, que é particularmente útil na redução da pressão intraocular associada a glaucoma. Aperfeiçoamentos na eficácia da redução da PIO, eficácia conservante e concentrações reduzidas de aditivos são conseguido utilizando-se as composições apresentadas, que incluem um agente ativo de prostaglandina (por exemplo, isopropil unoprostona, um metabólito de uma prostaglandina da série F,) juntamente com tensoativos não-iónicos, conservantes e agentes de ajuste de tonicidade não-iónicos selecionados.
BR9808016-4A 1997-03-17 1998-03-13 Composições e métodos para redução da hipertensão ocular BR9808016A (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BRPI9816218A BRPI9816218B1 (pt) 1997-03-17 1998-03-13 "composições para redução da hipertensão ocular, e seu uso na preparação de composições oftálmicas"

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81922197A 1997-03-17 1997-03-17
PCT/EP1998/001483 WO1998041208A1 (en) 1997-03-17 1998-03-13 Compositions and methods for reducing ocular hypertension

Publications (1)

Publication Number Publication Date
BR9808016A true BR9808016A (pt) 2000-03-08

Family

ID=38729083

Family Applications (2)

Application Number Title Priority Date Filing Date
BR9808016-4A BR9808016A (pt) 1997-03-17 1998-03-13 Composições e métodos para redução da hipertensão ocular
BRPI9816218A BRPI9816218B1 (pt) 1997-03-17 1998-03-13 "composições para redução da hipertensão ocular, e seu uso na preparação de composições oftálmicas"

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI9816218A BRPI9816218B1 (pt) 1997-03-17 1998-03-13 "composições para redução da hipertensão ocular, e seu uso na preparação de composições oftálmicas"

Country Status (33)

Country Link
EP (1) EP0969846B2 (pt)
JP (2) JP4920124B2 (pt)
KR (1) KR100555818B1 (pt)
CN (1) CN1236775C (pt)
AR (2) AR002194A1 (pt)
AT (1) ATE257385T1 (pt)
AU (1) AU738781B2 (pt)
BR (2) BR9808016A (pt)
CA (1) CA2280089C (pt)
CL (1) CL2009001870A1 (pt)
CO (1) CO4940427A1 (pt)
CY (1) CY2526B1 (pt)
CZ (1) CZ299833B6 (pt)
DE (1) DE69820997T3 (pt)
DK (1) DK0969846T4 (pt)
EE (1) EE04091B1 (pt)
ES (1) ES2214706T5 (pt)
HK (1) HK1026841A1 (pt)
HU (1) HU228896B1 (pt)
ID (1) ID22389A (pt)
IL (1) IL131041A0 (pt)
MY (1) MY122237A (pt)
NO (1) NO327713B1 (pt)
NZ (1) NZ337322A (pt)
PE (1) PE61899A1 (pt)
PL (1) PL197509B1 (pt)
PT (1) PT969846E (pt)
RU (1) RU2197970C2 (pt)
SI (1) SI0969846T2 (pt)
TW (1) TW527187B (pt)
UA (1) UA63938C2 (pt)
WO (1) WO1998041208A1 (pt)
ZA (1) ZA982188B (pt)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6011062A (en) * 1994-12-22 2000-01-04 Alcon Laboratories, Inc. Storage-stable prostaglandin compositions
AR002194A1 (es) * 1997-03-17 1998-01-07 Sanchez Reynaldo Alemany Instrumento computarizado para el analisis del movimiento.
US6187818B1 (en) * 1998-06-17 2001-02-13 Pharmacia & Upjohn Company Prostaglandins formulation and process
JP4880808B2 (ja) * 1999-11-15 2012-02-22 久光製薬株式会社 人工涙液型点眼剤組成物
JP4000505B2 (ja) * 1999-12-01 2007-10-31 第一三共株式会社 緑内障を治療するための併用剤
PT1321144E (pt) * 2000-09-13 2011-03-10 Santen Pharmaceutical Co Ltd Colírio
AU2002218527A1 (en) * 2000-12-05 2002-06-18 Sankyo Company Limited Ocular tension-lowering compositions for topical administration
US20020198209A1 (en) * 2001-05-03 2002-12-26 Allergan Sales Inc. Compositions having enhanced pharmacokinetic characteristics
US7074827B2 (en) 2002-10-24 2006-07-11 Sucampo Ag (Usa) Inc. Method for treating ocular hypertension and glaucoma
US20070208068A1 (en) * 2004-03-18 2007-09-06 R-Tech Ueno, Ltd. & Astellas Pharma Inc. Aqueous Composition Comprising Thiazole Derivative
US8569367B2 (en) 2004-11-16 2013-10-29 Allergan, Inc. Ophthalmic compositions and methods for treating eyes
GB0501192D0 (en) * 2005-01-20 2005-03-02 Resolution Chemicals Ltd Stable prostaglandin-containing compositions
US7851504B2 (en) * 2005-03-16 2010-12-14 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
ES2460967T3 (es) * 2005-08-02 2014-05-16 Santen Pharmaceutical Co., Ltd. Método para la prevención de la degradación de una sustancia térmicamente inestable
JP5252787B2 (ja) * 2005-08-02 2013-07-31 参天製薬株式会社 熱的に不安定な薬物の分解抑制方法
JP2007099647A (ja) * 2005-09-30 2007-04-19 Kobayashi Pharmaceut Co Ltd 粘膜適用組成物
US8168206B1 (en) 2005-10-06 2012-05-01 Allergan, Inc. Animal protein-free pharmaceutical compositions
RU2008140298A (ru) * 2006-03-13 2010-04-20 Р-Тек Уено, Лтд. (Jp) Водная композиция
CA2646424C (en) * 2006-03-17 2015-12-29 Johnson & Johnson Vision Care, Inc. Methods for stabilizing oxidatively unstable compositions
EP2077829A2 (en) * 2006-10-31 2009-07-15 Alcon Research, Ltd. Pai-1 binding modulators for the treatment of ocular disorders
WO2008096804A1 (ja) * 2007-02-07 2008-08-14 Teika Pharmaceutical Co., Ltd. ラタノプロスト含有点眼剤
JP2009073788A (ja) * 2007-09-21 2009-04-09 Teika Seiyaku Kk イソプロピルウノプロストン含有眼用組成物
EP2195033A1 (en) * 2007-10-08 2010-06-16 Fovea Pharmaceuticals SA Aqueous ophthalmic formulations
JP5583111B2 (ja) * 2008-03-17 2014-09-03 アルコン リサーチ， リミテッド ボレート−ポリオール錯体を含有する水性薬学的組成物
TWI544927B (zh) 2008-03-17 2016-08-11 愛爾康研究有限公司 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物
EP2127638A1 (en) 2008-05-30 2009-12-02 Santen Pharmaceutical Co., Ltd Method and composition for treating ocular hypertension and glaucoma
US8952051B2 (en) * 2009-11-05 2015-02-10 Allergan, Inc. Ophthalmic formulations containing substituted gamma lactams and methods for use thereof
WO2012141334A1 (en) * 2011-04-12 2012-10-18 R-Tech Ueno, Ltd. Aqueous ophthalmic composition
US20130029919A1 (en) 2011-07-26 2013-01-31 Allergan, Inc. Two part formulation system for opthalmic delivery
EP2567689A1 (en) 2011-09-12 2013-03-13 Visiotact Pharma Ophthtalmic compositions comprising prostaglandin F2 alpha derivatives and hyaluronic acid
US8957048B2 (en) 2011-10-06 2015-02-17 Allergan, Inc. Compositions for the treatment of dry eye
KR102017922B1 (ko) 2011-12-07 2019-09-03 알러간, 인코포레이티드 염-민감성 유액 시스템을 사용한 사람 눈물막으로의 효율적인 지질 전달 방법
US9907826B2 (en) 2011-12-07 2018-03-06 Allergan, Inc. Efficient lipid delivery to human tear film using a salt-sensitive emulsion system
UA121399C2 (uk) 2014-11-25 2020-05-25 Аллерган, Інк. Стабілізовані композиції для офтальмологічного застосування, які містять омега-3-кислоти
CA3113528A1 (en) * 2018-09-21 2020-03-26 Aufbau Medical Innovations Limited Compositions and methods for glaucoma
US11312922B2 (en) 2019-04-12 2022-04-26 Ecolab Usa Inc. Antimicrobial multi-purpose cleaner comprising a sulfonic acid-containing surfactant and methods of making and using the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69100171T2 (de) * 1990-05-22 1993-10-28 R Tech Ueno Ltd Synergistische Kombination zur ophthalmischen Verwendung.
IE920397A1 (en) * 1991-02-07 1992-08-12 Allergan Inc 2-decarboxyl-2-hydroxyalkyl-5-trans prostaglandin f¹derivatives
US5767154A (en) * 1991-02-07 1998-06-16 Allergan 5-trans-prostaglandins of the F series and their use as ocular hypotensives
CA2166722A1 (en) * 1994-05-06 1995-11-16 Manoj L. Maniar Use of vitamin e tocopheryl derivatives in ophthalmic compositions
US5631287A (en) † 1994-12-22 1997-05-20 Alcon Laboratories, Inc. Storage-stable prostaglandin compositions
US5558876A (en) * 1995-03-29 1996-09-24 Alcon Laboratories, Inc. Topical ophthalmic acidic drug formulations
AR002194A1 (es) * 1997-03-17 1998-01-07 Sanchez Reynaldo Alemany Instrumento computarizado para el analisis del movimiento.

Also Published As

Publication number Publication date
CA2280089C (en) 2009-03-03
HUP0002194A3 (en) 2012-08-28
CN1249687A (zh) 2000-04-05
DE69820997T3 (de) 2011-10-06
KR100555818B1 (ko) 2006-03-03
ATE257385T1 (de) 2004-01-15
CA2280089A1 (en) 1998-09-24
AU738781B2 (en) 2001-09-27
CZ325799A3 (cs) 2000-01-12
SI0969846T1 (en) 2004-06-30
KR20000076330A (ko) 2000-12-26
EP0969846B2 (en) 2010-08-25
PL197509B1 (pl) 2008-04-30
CL2009001870A1 (es) 2010-01-22
JP2001515502A (ja) 2001-09-18
DE69820997T2 (de) 2004-12-09
PE61899A1 (es) 1999-06-30
AR011192A1 (es) 2000-08-02
HU228896B1 (en) 2013-06-28
EE04091B1 (et) 2003-08-15
CY2526B1 (en) 2006-02-08
AR002194A1 (es) 1998-01-07
CZ299833B6 (cs) 2008-12-10
IL131041A0 (en) 2001-01-28
PL335168A1 (en) 2000-04-10
NO994481D0 (no) 1999-09-16
JP4920124B2 (ja) 2012-04-18
HUP0002194A2 (hu) 2000-12-28
SI0969846T2 (sl) 2010-12-31
CO4940427A1 (es) 2000-07-24
NO994481L (no) 1999-09-16
AU7035398A (en) 1998-10-12
PT969846E (pt) 2004-05-31
ES2214706T3 (es) 2004-09-16
ZA982188B (en) 1998-09-17
HK1026841A1 (en) 2000-12-29
BRPI9816218B1 (pt) 2016-04-12
EP0969846B1 (en) 2004-01-07
TW527187B (en) 2003-04-11
JP2010043110A (ja) 2010-02-25
DE69820997D1 (de) 2004-02-12
NO327713B1 (no) 2009-09-14
DK0969846T3 (da) 2004-04-13
EP0969846A1 (en) 2000-01-12
ID22389A (id) 1999-10-07
MY122237A (en) 2006-04-29
CN1236775C (zh) 2006-01-18
DK0969846T4 (da) 2010-12-20
NZ337322A (en) 2001-05-25
RU2197970C2 (ru) 2003-02-10
ES2214706T5 (es) 2011-02-02
WO1998041208A1 (en) 1998-09-24
UA63938C2 (uk) 2004-02-16
EE9900410A (et) 2000-04-17

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFERIMENTO DO PRESENTE PEDIDO, UMA VEZ QUE O MESMO NAO ATENDE AO DISPOSTO NOS ARTIGOS 8O, 11 E 25 DA LPI

B12B Appeal against refusal [chapter 12.2 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DA INT.CL: A61K 31/557, A61K 9/00, AO1B 1/00

Ipc: A61K 31/557 (2010.01), A61K 9/00 (2010.01), A61P 2