RU2015106688A - Препараты и способы получения препаратов для применения при опорожнении толстой кишки - Google Patents
Препараты и способы получения препаратов для применения при опорожнении толстой кишки Download PDFInfo
- Publication number
- RU2015106688A RU2015106688A RU2015106688A RU2015106688A RU2015106688A RU 2015106688 A RU2015106688 A RU 2015106688A RU 2015106688 A RU2015106688 A RU 2015106688A RU 2015106688 A RU2015106688 A RU 2015106688A RU 2015106688 A RU2015106688 A RU 2015106688A
- Authority
- RU
- Russia
- Prior art keywords
- fraction
- pharmaceutically acceptable
- acceptable excipient
- drug
- excipient component
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title claims abstract 24
- 239000003814 drug Substances 0.000 title claims abstract 24
- 238000000034 method Methods 0.000 title claims abstract 19
- 239000000546 pharmaceutical excipient Substances 0.000 claims abstract 22
- 239000003085 diluting agent Substances 0.000 claims abstract 14
- 239000002518 antifoaming agent Substances 0.000 claims abstract 12
- 230000000181 anti-adherent effect Effects 0.000 claims abstract 6
- 239000011230 binding agent Substances 0.000 claims abstract 6
- 239000007884 disintegrant Substances 0.000 claims abstract 6
- 238000002360 preparation method Methods 0.000 claims abstract 6
- 239000003381 stabilizer Substances 0.000 claims abstract 6
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical class [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims abstract 5
- 229940069428 antacid Drugs 0.000 claims abstract 5
- 239000003159 antacid agent Substances 0.000 claims abstract 5
- 230000001458 anti-acid effect Effects 0.000 claims abstract 5
- 239000008141 laxative Substances 0.000 claims abstract 5
- 230000002475 laxative effect Effects 0.000 claims abstract 5
- 239000000314 lubricant Substances 0.000 claims abstract 5
- 150000007524 organic acids Chemical class 0.000 claims abstract 5
- 230000003204 osmotic effect Effects 0.000 claims abstract 5
- 235000005985 organic acids Nutrition 0.000 claims abstract 4
- 239000011248 coating agent Substances 0.000 claims abstract 3
- 238000000576 coating method Methods 0.000 claims abstract 3
- 239000007787 solid Substances 0.000 claims abstract 3
- 239000000203 mixture Substances 0.000 claims abstract 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 6
- 229960005070 ascorbic acid Drugs 0.000 claims 3
- 235000010323 ascorbic acid Nutrition 0.000 claims 3
- 239000011668 ascorbic acid Substances 0.000 claims 3
- 229940093915 gynecological organic acid Drugs 0.000 claims 3
- 239000000395 magnesium oxide Substances 0.000 claims 3
- CPLXHLVBOLITMK-UHFFFAOYSA-N magnesium oxide Inorganic materials [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 claims 3
- AXZKOIWUVFPNLO-UHFFFAOYSA-N magnesium;oxygen(2-) Chemical compound [O-2].[Mg+2] AXZKOIWUVFPNLO-UHFFFAOYSA-N 0.000 claims 3
- GOZDTZWAMGHLDY-UHFFFAOYSA-L sodium picosulfate Chemical compound [Na+].[Na+].C1=CC(OS(=O)(=O)[O-])=CC=C1C(C=1N=CC=CC=1)C1=CC=C(OS([O-])(=O)=O)C=C1 GOZDTZWAMGHLDY-UHFFFAOYSA-L 0.000 claims 3
- 229960005077 sodium picosulfate Drugs 0.000 claims 3
- 239000002775 capsule Substances 0.000 claims 2
- AMTWCFIAVKBGOD-UHFFFAOYSA-N dioxosilane;methoxy-dimethyl-trimethylsilyloxysilane Chemical compound O=[Si]=O.CO[Si](C)(C)O[Si](C)(C)C AMTWCFIAVKBGOD-UHFFFAOYSA-N 0.000 claims 2
- 239000008187 granular material Substances 0.000 claims 2
- 239000006187 pill Substances 0.000 claims 2
- 229940083037 simethicone Drugs 0.000 claims 2
- WSVLPVUVIUVCRA-KPKNDVKVSA-N Alpha-lactose monohydrate Chemical compound O.O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O WSVLPVUVIUVCRA-KPKNDVKVSA-N 0.000 claims 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims 1
- 210000001072 colon Anatomy 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 150000002148 esters Chemical group 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 229960001021 lactose monohydrate Drugs 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 229960000869 magnesium oxide Drugs 0.000 claims 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims 1
- 239000008108 microcrystalline cellulose Substances 0.000 claims 1
- 229940016286 microcrystalline cellulose Drugs 0.000 claims 1
- 239000000600 sorbitol Substances 0.000 claims 1
- 229960002920 sorbitol Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/08—Oxides; Hydroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2893—Tablet coating processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261676608P | 2012-07-27 | 2012-07-27 | |
| US61/676,608 | 2012-07-27 | ||
| PCT/IB2013/001640 WO2014016671A2 (en) | 2012-07-27 | 2013-07-26 | Formulations and methods of manufacturing formulations for use in colonic evacuation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2015106688A true RU2015106688A (ru) | 2016-09-20 |
Family
ID=49997911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015106688A RU2015106688A (ru) | 2012-07-27 | 2013-07-26 | Препараты и способы получения препаратов для применения при опорожнении толстой кишки |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US10166219B2 (enExample) |
| EP (1) | EP2877163B1 (enExample) |
| JP (1) | JP6454640B2 (enExample) |
| KR (1) | KR102152873B1 (enExample) |
| CN (2) | CN104797244B (enExample) |
| AU (1) | AU2013294737B2 (enExample) |
| BR (1) | BR112015001640A2 (enExample) |
| CA (1) | CA2880282C (enExample) |
| CY (1) | CY1121852T1 (enExample) |
| DK (1) | DK2877163T3 (enExample) |
| ES (1) | ES2717282T3 (enExample) |
| HR (1) | HRP20190550T1 (enExample) |
| HU (1) | HUE043852T2 (enExample) |
| IL (1) | IL236791B (enExample) |
| IN (1) | IN2015DN00637A (enExample) |
| MX (1) | MX366707B (enExample) |
| NZ (1) | NZ704014A (enExample) |
| PH (1) | PH12015500165A1 (enExample) |
| PL (1) | PL2877163T3 (enExample) |
| PT (1) | PT2877163T (enExample) |
| RU (1) | RU2015106688A (enExample) |
| SI (1) | SI2877163T1 (enExample) |
| TR (1) | TR201904884T4 (enExample) |
| WO (1) | WO2014016671A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2011342368B2 (en) | 2010-12-13 | 2016-11-17 | Rite-Prep Pty Ltd | Gastric and colonic formulations and methods for making and using them |
| US10166219B2 (en) | 2012-07-27 | 2019-01-01 | Redhill Bipharma Ltd. | Formulations and methods of manufacturing formulations for use in colonic evacuation |
| IN2013MU02911A (enExample) * | 2013-09-10 | 2015-07-03 | Cadila Healthcare Ltd | |
| KR101420315B1 (ko) | 2014-03-19 | 2014-07-17 | 남봉길 | 약학적 액제 조성물 |
| RU2018105869A (ru) | 2015-08-17 | 2019-09-19 | Ферринг Б.В. | Жидкие составы, содержащие пикосульфат и цитрат магния |
| WO2018009761A1 (en) * | 2016-07-08 | 2018-01-11 | Ferring B.V. | Stabilized liquid formulations containing picosulfate |
| EP3345591A1 (en) * | 2017-01-06 | 2018-07-11 | Oystershell NV | Oral dosage form for enhanced solubilization of a poorly soluble active agent and method of preparation |
| JP7340572B2 (ja) * | 2021-08-20 | 2023-09-07 | セトラスホールディングス株式会社 | 酸化マグネシウム錠剤 |
Family Cites Families (116)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3459863A (en) * | 1966-10-14 | 1969-08-05 | Merck & Co Inc | Color-stable ascorbic acid tablet |
| US4186025A (en) | 1975-09-25 | 1980-01-29 | Merck & Co., Inc. | Aqueous polysaccharide composition |
| US4452779A (en) | 1982-02-03 | 1984-06-05 | Cockerill Vernon | Composition and method of treating lactating mammals |
| DK454683D0 (da) | 1983-10-03 | 1983-10-03 | Mogens Gjerloev | Tarmreguleringsmiddel til behandling af diarre hos dyr samt anvendelse heraf |
| EP0222834A4 (en) | 1985-04-18 | 1989-10-04 | Borody Thomas J | TREATMENT OF NON-ULCERATIVE DYSPEPSIA WITH BISMUTOUS SALTS. |
| US4766004A (en) | 1986-12-19 | 1988-08-23 | Warner-Lambert Company | Crunchy, highly palatable, bulk-increasing, dietary fiber supplement composition |
| IL86859A (en) | 1987-07-10 | 1991-12-15 | E Z Em Inc | Aqueous cathartic solution containing inorganic salts |
| EP0439453B1 (en) | 1987-10-12 | 1994-01-19 | Exomed Australia Pty. Ltd. (ACN 051 976 446) | Improved method for treatment of gastrointestinal disorders |
| DE3889547T2 (de) | 1987-12-24 | 1994-11-17 | Borody Thomas J | Orthostatische waschlösungen. |
| US5443826A (en) | 1988-08-02 | 1995-08-22 | Borody; Thomas J. | Treatment of gastro-intestinal disorders with a fecal composition or a composition of bacteroides and E. Coli |
| WO1990001335A1 (en) | 1988-08-02 | 1990-02-22 | Borody Thomas J | Treatment of gastro-intestinal disorders |
| US5213807A (en) | 1990-05-03 | 1993-05-25 | Chemburkar Pramod B | Pharmaceutical composition containing ibuprofen and a prostaglandin |
| US5232699A (en) | 1990-07-26 | 1993-08-03 | The Proctor & Gamble Company | Laxative compositions |
| WO1992006690A1 (en) | 1990-10-22 | 1992-04-30 | Borody Thomas J | Treatment of non-inflammatory and non-infectious bowel disorders |
| US5519014A (en) | 1990-10-22 | 1996-05-21 | Borody; Thomas J. | Treatment of non-inflammatory and non-infectious bowel disorders |
| US5173296A (en) | 1990-11-16 | 1992-12-22 | The Procter & Gamble Company | Compositions containing psyllium |
| JPH06132767A (ja) | 1992-10-22 | 1994-05-13 | Rohm Co Ltd | 圧電発振子 |
| DK0686034T3 (da) | 1993-02-26 | 2001-08-27 | Procter & Gamble | Bisacodyl-doseringsform |
| JP2974550B2 (ja) | 1993-06-01 | 1999-11-10 | ビオフェルミン製薬株式会社 | 経口投与用固体組成物 |
| WO1995011024A1 (en) * | 1993-10-19 | 1995-04-27 | The Procter & Gamble Company | Picosulphate dosage form |
| JP3850891B2 (ja) | 1994-03-01 | 2006-11-29 | ゼリア新薬工業株式会社 | 緩下効果を有する組成物 |
| AUPM695294A0 (en) | 1994-07-20 | 1994-08-11 | Borody, Thomas Julius | Improved combination therapy dose unit |
| AUPM864894A0 (en) | 1994-10-07 | 1994-11-03 | Borody, Thomas Julius | Treatment of bowel-dependent neurological disorders |
| RU2098100C1 (ru) | 1995-10-11 | 1997-12-10 | Максимова Ирина Сергеевна | Ирригационный раствор для офтальмологических операций |
| US6103268A (en) | 1995-11-03 | 2000-08-15 | Borody; Thomas Julius | Administering osmotic colonic evacuant containing a picosulfate |
| AU771576B2 (en) | 1995-11-03 | 2004-03-25 | Red Hill Biopharma Ltd. | Improved preparation for colonic evacuation |
| AUPN634595A0 (en) * | 1995-11-03 | 1995-11-30 | Borody, Thomas Julius | Improved method for colonic evacuation |
| NZ333493A (en) | 1995-11-03 | 2000-06-23 | Nicolas Peter Shortis | Method of evacuating a patient's colon by oral administration of an osmotic colonic evacuant in powder form |
| US6087386A (en) | 1996-06-24 | 2000-07-11 | Merck & Co., Inc. | Composition of enalapril and losartan |
| EP1380308B1 (en) * | 1996-07-12 | 2008-07-09 | Daiichi Pharmaceutical Co., Ltd. | Quickly disintegrable compression-molded materials and process for producing the same |
| US5948787A (en) | 1997-02-28 | 1999-09-07 | Alza Corporation | Compositions containing opiate analgesics |
| US6162464A (en) | 1997-03-31 | 2000-12-19 | Inkine Pharmaceutical, Inc. | Non-aqueous colonic purgative formulations |
| DE69839261T2 (de) | 1997-04-01 | 2009-03-26 | Borody, Thomas Julius, Five Dock | Verfahren und zusammensetzungen zur behandlung entzündlicher darmerkrankungen |
| US6551632B2 (en) | 1997-04-01 | 2003-04-22 | Thomas Julius Borody | Methods and compositions for treating inflammatory bowel disease |
| EP0988858A1 (en) | 1997-04-18 | 2000-03-29 | Taisho Pharmaceutical Co., Ltd | Microemulsion |
| AUPO665397A0 (en) | 1997-05-07 | 1997-05-29 | Borody, Thomas Julius | Novel therapy for constipation |
| AR016827A1 (es) | 1997-08-22 | 2001-08-01 | Smithkline Beecham Corp | PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA |
| CN1981747A (zh) * | 1997-08-22 | 2007-06-20 | 史密丝克莱恩比彻姆公司 | 快速崩解的甲基纤维素片剂 |
| AR017512A1 (es) * | 1997-08-22 | 2001-09-12 | Smithkline Beecham Corp | Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas |
| JP4092748B2 (ja) | 1997-09-05 | 2008-05-28 | ニプロ株式会社 | 腸管洗浄液 |
| US5843477A (en) * | 1997-09-30 | 1998-12-01 | Bayer Corporation | Lubricants for use in tabletting |
| NZ505123A (en) * | 1997-12-19 | 2003-07-25 | Smithkline Beecham Corp | Process for manufacturing bite-dispersion tablets by compressing medicaments and other ingredients into granulates then compressing the granulates and other ingredients into tablets, and the tablets thereof |
| AUPP325398A0 (en) | 1998-04-30 | 1998-05-21 | Borody, Thomas J. | Improved method for eradicating h. pylori |
| AUPP437698A0 (en) | 1998-06-30 | 1998-07-23 | Baumgart, Karl | Methods for treatment of coronary, carotid and other vascular disease |
| EP1005863A1 (en) | 1998-12-04 | 2000-06-07 | Synthelabo | Controlled-release dosage forms comprising a short acting hypnotic or a salt thereof |
| US6245740B1 (en) | 1998-12-23 | 2001-06-12 | Amgen Inc. | Polyol:oil suspensions for the sustained release of proteins |
| DE60040214D1 (de) | 1999-02-26 | 2008-10-23 | Shionogi & Co | Kaubare weichkapseln mit verbesserten verabreichungseigenschaften sowie verfahren zu deren herstellung |
| US6858403B2 (en) | 1999-05-11 | 2005-02-22 | M-Biotech, Inc. | Polymer matrix containing catalase co-immobilized with analytic enzyme that generates hydrogen peroxide |
| DE19930030B4 (de) | 1999-06-30 | 2004-02-19 | Meduna Arzneimittel Gmbh | CO-3-ungesättigte Fettsäuren enthaltende orale Darreichungsform |
| CN1288730A (zh) | 1999-09-07 | 2001-03-28 | 麦克内尔-Ppc股份有限公司 | 轻泻组合物 |
| US6774111B1 (en) | 2000-03-14 | 2004-08-10 | Abbott Laboratories | Carbohydrate system and a method for providing nutrition to a diabetic |
| NZ522036A (en) | 2000-04-19 | 2004-04-30 | Borody Thomas J | Compositions and therapies for hyperlipidaemia-associated disorders |
| JP2003535903A (ja) | 2000-06-19 | 2003-12-02 | ミューコプロテック・プロプライエタリー・リミテッド | プロバイオティックを用いた、粘膜表面での細菌またはウイルス感染の免疫療法または治療、およびそのための組成物 |
| AUPQ854100A0 (en) | 2000-07-03 | 2000-07-27 | Helirad Pty Ltd | Methods for monitoring treatment of helicobacter infection |
| AUPQ899700A0 (en) | 2000-07-25 | 2000-08-17 | Borody, Thomas Julius | Probiotic recolonisation therapy |
| KR20030087009A (ko) | 2001-02-27 | 2003-11-12 | 랜박시 래보러터리스 리미티드 | 세프포독심 프록세틸의 경구용 약학 조성물 |
| EP1367907B1 (en) | 2001-03-13 | 2007-02-28 | Kellogg Company | Aerated food component |
| US6790453B2 (en) | 2001-03-14 | 2004-09-14 | Mccormick & Company, Inc. | Encapsulation compositions and process for preparing the same |
| US7815956B2 (en) | 2001-04-27 | 2010-10-19 | Pepsico | Use of erythritol and D-tagatose in diet or reduced-calorie beverages and food products |
| IL159129A0 (en) | 2001-06-01 | 2004-05-12 | Pozen Inc | PHARMACEUTICAL COMPOSITIONS FOR THE COORDINATED DELIVERY OF NSAIDs |
| AU2002315779B2 (en) | 2001-07-05 | 2007-03-22 | Wakunaga Pharmaceutical Co.,Ltd | Soft capsules |
| US20030092724A1 (en) | 2001-09-18 | 2003-05-15 | Huaihung Kao | Combination sustained release-immediate release oral dosage forms with an opioid analgesic and a non-opioid analgesic |
| AUPS017702A0 (en) | 2002-01-25 | 2002-02-14 | Atopic Pty Ltd | Methods and compositions for the treatment of asthma and related disorders |
| AUPS088702A0 (en) | 2002-03-04 | 2002-03-28 | Borody, Thomas Julius | Electrolyte purgative |
| US6753009B2 (en) | 2002-03-13 | 2004-06-22 | Mcneil-Ppc, Inc. | Soft tablet containing high molecular weight polyethylene oxide |
| ES2320748T5 (es) | 2002-04-05 | 2017-02-20 | Euro-Celtique S.A. | Matriz para la liberación sostenida, invariable e independiente de compuestos activos |
| US6946149B2 (en) | 2002-04-30 | 2005-09-20 | Braintree Laboratories, Inc. | Salt solution for colon cleansing |
| JP4591742B2 (ja) | 2003-01-06 | 2010-12-01 | 大正製薬株式会社 | ジオクチルソジウムスルホサクシネート配合製剤およびその製造方法 |
| AU2003900553A0 (en) | 2003-02-10 | 2003-02-20 | Borody, Thomas Julius | Novel Improved Method for Detection of Dientamoeba fragilis and other Parasites |
| RU2005134364A (ru) | 2003-04-08 | 2006-06-10 | Проджиникс Фармасьютикалз, Инк. (Us) | Комбинированное лечение запора |
| AU2004238321B2 (en) | 2003-05-07 | 2009-08-27 | Samyang Biopharmaceuticals Corporation | Highly plastic granules for making fast melting tablets |
| US20040265378A1 (en) | 2003-06-25 | 2004-12-30 | Yingxu Peng | Method and compositions for producing granules containing high concentrations of biologically active substances |
| US7687075B2 (en) * | 2003-11-19 | 2010-03-30 | Salix Pharmaceuticals, Ltd. | Colonic purgative composition with soluble binding agent |
| JP2005255595A (ja) | 2004-03-10 | 2005-09-22 | Taisho Pharmaceut Co Ltd | ジオクチルソジウムスルホサクシネート配合錠剤 |
| JP2005272401A (ja) | 2004-03-25 | 2005-10-06 | Tendou Seiyaku Kk | チュアブル錠 |
| CA2559239C (en) | 2004-04-13 | 2021-04-06 | Boehringer Ingelheim International Gmbh | Use of simethicone and sodium picosulphate in constipated patients suffering from bloated feeling and gas discomfort during the night |
| KR100749229B1 (ko) | 2005-04-29 | 2007-08-13 | (주)아모레퍼시픽 | 당 및 당알콜을 함유하는 변비개선용 조성물 |
| US20060275223A1 (en) | 2005-06-02 | 2006-12-07 | Burr James B | Erythritol compositions for teeth and gums |
| DE102006033014A1 (de) | 2005-09-13 | 2007-04-05 | Volkswagen Ag | Eingabevorrichtung für ein Kraftfahrzeug |
| WO2007057924A1 (en) | 2005-11-21 | 2007-05-24 | Panacea Biotec Ltd | Laxative composition on the basis of triphala |
| CA2635313C (en) | 2005-12-29 | 2013-12-31 | Osmotica Corp. | Triple combination release multi-layered tablet |
| JP5006567B2 (ja) | 2006-04-14 | 2012-08-22 | 花王株式会社 | 口腔用固形製剤 |
| EP2068837A2 (en) | 2006-07-28 | 2009-06-17 | Dr. Reddy's Laboratories Ltd. | Granular pharmaceutical compositions |
| WO2008021394A2 (en) | 2006-08-15 | 2008-02-21 | Theraquest Biosciences, Llc | Pharmaceutical formulations of cannabinoids and method of use |
| WO2008027442A2 (en) | 2006-08-30 | 2008-03-06 | Theraquest Biosciences, Llc | Abuse deterrent oral pharmaceutical formulations of opioid agonists and method of use |
| DE602007007355D1 (de) | 2006-12-04 | 2010-08-05 | Du Pont | Beschichtungszusammensetzung aus acrylpolyol |
| AU2008253583A1 (en) | 2007-05-17 | 2008-11-27 | David Lubowski | Combination laxative compositions comprising a colonic stimulant and a bulking laxative |
| CA2687192C (en) | 2007-06-04 | 2015-11-24 | Egalet A/S | Controlled release pharmaceutical compositions for prolonged effect |
| WO2008148742A2 (de) | 2007-06-06 | 2008-12-11 | Basf Se | Pharmazeutische formulierung für die herstellung von schnell zerfallenden tabletten |
| JP2010529073A (ja) | 2007-06-06 | 2010-08-26 | ビーエーエスエフ ソシエタス・ヨーロピア | チュアブル錠及びトローチ剤製造のための医薬製剤 |
| DK2264042T3 (da) | 2007-07-27 | 2012-08-20 | Cargill Inc | Mikronisering af polyoler |
| US20100233278A1 (en) | 2007-09-27 | 2010-09-16 | Akiko Ookawa | Rapidly disintegrating solid preparation |
| PL2572705T3 (pl) | 2007-10-01 | 2018-01-31 | Lesvi Laboratorios Sl | Tabletki ulegające rozpadowi w jamie ustnej |
| CN101406457A (zh) * | 2007-10-12 | 2009-04-15 | 辉凌国际制药（瑞士）有限公司 | 制备药物产品的方法 |
| US8481083B2 (en) * | 2007-10-12 | 2013-07-09 | Ferring International Center S.A. | Granular compositions of magnesium oxide and citric acid and uses thereof |
| MX2010004222A (es) | 2007-10-19 | 2010-09-14 | Purdue Research Foundation | Formulaciones solidas de compuestos cristalinos. |
| JP5258268B2 (ja) | 2007-11-19 | 2013-08-07 | フロイント産業株式会社 | 球形粒の製造方法 |
| US20090155363A1 (en) | 2007-12-14 | 2009-06-18 | Todd Maibach | Methods for oral administration of active drugs |
| US20090169622A1 (en) * | 2007-12-27 | 2009-07-02 | Roxane Laboratories, Inc. | Delayed-release oral pharmaceutical composition for treatment of colonic disorders |
| WO2009084678A1 (ja) | 2007-12-28 | 2009-07-09 | Sawai Pharmaceutical Co., Ltd. | 口腔内崩壊錠およびその製造方法 |
| US20090258090A1 (en) | 2008-04-11 | 2009-10-15 | Braintree Laboratories, Inc. | Colon cleansing solution |
| US20100178413A1 (en) | 2008-12-17 | 2010-07-15 | Mark Gorris | Food-based Supplement Delivery System |
| US20100285164A1 (en) | 2009-05-11 | 2010-11-11 | Jrs Pharma | Orally Disintegrating Excipient |
| WO2010138439A1 (en) | 2009-05-28 | 2010-12-02 | Aptapharma, Inc. | Multiparticulate controlled-release selective serotonin reuptake inhibitor formulations |
| JP2011019046A (ja) | 2009-07-08 | 2011-01-27 | Nec Commun Syst Ltd | 通信制御装置、通信制御方法、プログラム、及び記録媒体 |
| JP5674667B2 (ja) * | 2009-08-11 | 2015-02-25 | 富士化学工業株式会社 | 崩壊性粒子組成物及び口腔内速崩壊錠 |
| US9446055B2 (en) * | 2009-08-11 | 2016-09-20 | Fuji Chemical Industry Co., Ltd. | Disintegrating particle composition and orally rapidly disintegrating tablet |
| JP5663238B2 (ja) | 2009-08-31 | 2015-02-04 | ライオン株式会社 | 内服固形製剤及びその製造方法 |
| JP2011157348A (ja) * | 2010-01-05 | 2011-08-18 | Fuji Chem Ind Co Ltd | 崩壊性高強度球状粒子組成物 |
| JP5711520B2 (ja) | 2010-01-06 | 2015-04-30 | 三洋化成工業株式会社 | 外用組成物 |
| US20110218216A1 (en) | 2010-01-29 | 2011-09-08 | Kumaravel Vivek | Extended release pharmaceutical composition of donepezil |
| JP2012079118A (ja) | 2010-10-01 | 2012-04-19 | Toyota Motor Corp | 走行支援装置及び方法 |
| AU2011342368B2 (en) * | 2010-12-13 | 2016-11-17 | Rite-Prep Pty Ltd | Gastric and colonic formulations and methods for making and using them |
| IN2014DN03373A (enExample) | 2011-10-27 | 2015-06-05 | Borody Thomas J | |
| US10166219B2 (en) * | 2012-07-27 | 2019-01-01 | Redhill Bipharma Ltd. | Formulations and methods of manufacturing formulations for use in colonic evacuation |
| JP2015531770A (ja) | 2012-08-29 | 2015-11-05 | サリックス ファーマシューティカルズ，インコーポレイテッド | 緩下剤組成物、ならびに便秘および関連胃腸疾患および症状を処置するための方法 |
-
2013
- 2013-07-26 US US14/417,172 patent/US10166219B2/en active Active
- 2013-07-26 KR KR1020157004752A patent/KR102152873B1/ko not_active Expired - Fee Related
- 2013-07-26 CN CN201380049674.4A patent/CN104797244B/zh not_active Expired - Fee Related
- 2013-07-26 HU HUE13822195A patent/HUE043852T2/hu unknown
- 2013-07-26 BR BR112015001640A patent/BR112015001640A2/pt active Search and Examination
- 2013-07-26 MX MX2015000971A patent/MX366707B/es active IP Right Grant
- 2013-07-26 IN IN637DEN2015 patent/IN2015DN00637A/en unknown
- 2013-07-26 AU AU2013294737A patent/AU2013294737B2/en active Active
- 2013-07-26 CA CA2880282A patent/CA2880282C/en active Active
- 2013-07-26 RU RU2015106688A patent/RU2015106688A/ru unknown
- 2013-07-26 PT PT13822195T patent/PT2877163T/pt unknown
- 2013-07-26 ES ES13822195T patent/ES2717282T3/es active Active
- 2013-07-26 SI SI201331432T patent/SI2877163T1/sl unknown
- 2013-07-26 CN CN201810101389.7A patent/CN108175773A/zh active Pending
- 2013-07-26 TR TR2019/04884T patent/TR201904884T4/tr unknown
- 2013-07-26 DK DK13822195.7T patent/DK2877163T3/en active
- 2013-07-26 EP EP13822195.7A patent/EP2877163B1/en active Active
- 2013-07-26 JP JP2015523620A patent/JP6454640B2/ja not_active Expired - Fee Related
- 2013-07-26 NZ NZ704014A patent/NZ704014A/en unknown
- 2013-07-26 PL PL13822195T patent/PL2877163T3/pl unknown
- 2013-07-26 WO PCT/IB2013/001640 patent/WO2014016671A2/en not_active Ceased
- 2013-07-26 HR HRP20190550TT patent/HRP20190550T1/hr unknown
-
2015
- 2015-01-19 IL IL236791A patent/IL236791B/en active IP Right Grant
- 2015-01-26 PH PH12015500165A patent/PH12015500165A1/en unknown
-
2018
- 2018-11-13 US US16/189,847 patent/US10493065B2/en not_active Expired - Fee Related
-
2019
- 2019-03-26 CY CY20191100344T patent/CY1121852T1/el unknown
- 2019-10-25 US US16/663,652 patent/US11058671B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2015106688A (ru) | Препараты и способы получения препаратов для применения при опорожнении толстой кишки | |
| US9937142B2 (en) | Gastric retentive pharmaceutical compositions for treatment and prevention of CNS disorders | |
| KR101378973B1 (ko) | 구형에 가까운 형태의 다중 투여 단위 정제를 포함하는 경질 캡슐 복합 제형 및 이의 제조방법 | |
| JP2010534721A (ja) | パルス型胃滞留性製剤 | |
| HRP20161262T1 (hr) | Tablete ulipristal acetata | |
| RU2006122517A (ru) | Фармацевтический состав для прямого прессования, предназначенный для перорального введения cci-779 | |
| RU2013105481A (ru) | Комбинированная система доставки с немедленным/замедленным высвобождением для лекарственных средств с коротким периодом полувыведения, в том числе для ремоглифлозина | |
| JP2015522652A5 (enExample) | ||
| CN105338970B (zh) | 包含他达拉非和坦洛新的药物胶囊复合制剂 | |
| HRP20240045T1 (hr) | Tablete s trenutnim oslobađanjem koje sadrže lijek i postupci za proizvodnju tableta | |
| RU2012150409A (ru) | Препарат ацеклофенака с медленным высвобождением, обеспечивающий оптимальное фармакологическое и клиническое действие при приеме один раз в день | |
| CA2764172A1 (en) | A thrombin receptor antagonist and clopidogrel fixed dose tablet | |
| KR102283582B1 (ko) | 푸마르산 에스테르를 함유하는 미니-정제 형태의 약제학적 제제 | |
| US20110142944A1 (en) | Andrographis extract formulations | |
| HK1207563A1 (en) | Acamprosate formulations, methods of using the same, and combinations comprising the same | |
| CN103371982A (zh) | 盐酸帕罗西汀肠溶控释片新型处方组成及制备方法 | |
| CN103860511B (zh) | 一种含有厄贝沙坦和苯磺酸氨氯地平的药用组合物及其制备方法 | |
| CN202211874U (zh) | 一种复方辛伐他汀烟酸双释片胶囊 | |
| CN102526049A (zh) | 一种复方双氯芬酸钠缓释制剂及其制备方法 | |
| CN102641253B (zh) | 缬沙坦缓释片及其制备方法 | |
| CN101721380A (zh) | 一种制备缓控释制剂的方法 | |
| JP6106359B2 (ja) | ロキソプロフェンナトリウムとビタミンｂ１を含有する固形製剤 | |
| RU2009121838A (ru) | Пероральная лекарственая форма, содержащая соединения тризамещенного глицерина | |
| CN105476963A (zh) | 一种盐酸阿考替胺缓释微丸及制备方法 | |
| Das et al. | Design and development of a dual-drug loaded pulsatile capsule for treatment of hypertension–in vitro and ex vivo studies |