MX366707B - Formulaciones y métodos para elaborar formulaciones para utilizarse en evacuación colónica. - Google Patents

Formulaciones y métodos para elaborar formulaciones para utilizarse en evacuación colónica.

Info

Publication number
MX366707B
MX366707B MX2015000971A MX2015000971A MX366707B MX 366707 B MX366707 B MX 366707B MX 2015000971 A MX2015000971 A MX 2015000971A MX 2015000971 A MX2015000971 A MX 2015000971A MX 366707 B MX366707 B MX 366707B
Authority
MX
Mexico
Prior art keywords
formulations
methods
granular fraction
manufacturing
intra
Prior art date
Application number
MX2015000971A
Other languages
English (en)
Other versions
MX2015000971A (es
Inventor
Fathi Reza
Laughlin Mclean Patrick
Original Assignee
Redhill Biopharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Redhill Biopharma Ltd filed Critical Redhill Biopharma Ltd
Publication of MX2015000971A publication Critical patent/MX2015000971A/es
Publication of MX366707B publication Critical patent/MX366707B/es

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08—Oxides; Hydroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Se describen en la presente formulaciones y métodos para elaborar formulaciones para uso en la evacuación colónica. En una modalidad, una formulación de dosis sólida incluye una fracción intra-granular entre-mezclada con una fracción extra-granular, en donde la fracción intra-granular incluye gránulos que comprenden al menos un agente evacuatorio osmótico, al menos un antiácido, y un primer componente excipiente farmacéuticamente aceptable, y en donde la fracción extra-granular incluye uno o más ácidos orgánicos, un elemento lubricante no metálico, y un segundo componente excipiente farmacéuticamente aceptable.
MX2015000971A 2012-07-27 2013-07-26 Formulaciones y métodos para elaborar formulaciones para utilizarse en evacuación colónica. MX366707B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261676608P 2012-07-27 2012-07-27
PCT/IB2013/001640 WO2014016671A2 (en) 2012-07-27 2013-07-26 Formulations and methods of manufacturing formulations for use in colonic evacuation

Publications (2)

Publication Number Publication Date
MX2015000971A MX2015000971A (es) 2015-07-14
MX366707B true MX366707B (es) 2019-07-22

Family

ID=49997911

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015000971A MX366707B (es) 2012-07-27 2013-07-26 Formulaciones y métodos para elaborar formulaciones para utilizarse en evacuación colónica.

Country Status (24)

Country Link
US (3) US10166219B2 (es)
EP (1) EP2877163B1 (es)
JP (1) JP6454640B2 (es)
KR (1) KR102152873B1 (es)
CN (2) CN104797244B (es)
AU (1) AU2013294737B2 (es)
BR (1) BR112015001640A2 (es)
CA (1) CA2880282C (es)
CY (1) CY1121852T1 (es)
DK (1) DK2877163T3 (es)
ES (1) ES2717282T3 (es)
HR (1) HRP20190550T1 (es)
HU (1) HUE043852T2 (es)
IL (1) IL236791B (es)
IN (1) IN2015DN00637A (es)
MX (1) MX366707B (es)
NZ (1) NZ704014A (es)
PH (1) PH12015500165A1 (es)
PL (1) PL2877163T3 (es)
PT (1) PT2877163T (es)
RU (1) RU2015106688A (es)
SI (1) SI2877163T1 (es)
TR (1) TR201904884T4 (es)
WO (1) WO2014016671A2 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112013014827A2 (pt) 2010-12-13 2016-10-04 Antony Wettstein formulações gástricas e colônicas e métodos para produzir e usar as mesmas
IN2015DN00637A (es) * 2012-07-27 2015-06-26 Redhill Biopharma Ltd
IN2013MU02911A (es) * 2013-09-10 2015-07-03 Cadila Healthcare Ltd
KR101420315B1 (ko) 2014-03-19 2014-07-17 남봉길 약학적 액제 조성물
MX2018001965A (es) 2015-08-17 2018-11-09 Ferring Bv Formulaciones liquidas que contienen picosulfato y citrato de magnesio.
TW201804996A (zh) 2016-07-08 2018-02-16 輝凌責任有限公司 含有匹可硫酸鹽(picosulfate)之安定液體調配物
EP3345591A1 (en) * 2017-01-06 2018-07-11 Oystershell NV Oral dosage form for enhanced solubilization of a poorly soluble active agent and method of preparation
JP7340572B2 (ja) * 2021-08-20 2023-09-07 セトラスホールディングス株式会社 酸化マグネシウム錠剤

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CA2880282C (en) 2020-09-01
US11058671B2 (en) 2021-07-13
DK2877163T3 (en) 2019-04-15
KR20150044027A (ko) 2015-04-23
HRP20190550T1 (hr) 2019-05-31
JP2015522652A (ja) 2015-08-06
AU2013294737B2 (en) 2018-05-24
US10166219B2 (en) 2019-01-01
ES2717282T3 (es) 2019-06-20
EP2877163B1 (en) 2019-03-20
CA2880282A1 (en) 2014-01-30
TR201904884T4 (tr) 2019-05-21
CN108175773A (zh) 2018-06-19
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US20190240205A1 (en) 2019-08-08
IL236791A0 (en) 2015-03-31
US20150272937A1 (en) 2015-10-01
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EP2877163A4 (en) 2015-12-09
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PL2877163T3 (pl) 2019-08-30
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