RU2005141226A - Конкретное глюкокортикостероидное соединение, обладающее противовоспалительной активностью - Google Patents
Конкретное глюкокортикостероидное соединение, обладающее противовоспалительной активностью Download PDFInfo
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- RU2005141226A RU2005141226A RU2005141226/04A RU2005141226A RU2005141226A RU 2005141226 A RU2005141226 A RU 2005141226A RU 2005141226/04 A RU2005141226/04 A RU 2005141226/04A RU 2005141226 A RU2005141226 A RU 2005141226A RU 2005141226 A RU2005141226 A RU 2005141226A
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- physiologically acceptable
- formula
- compound
- acceptable solvate
- pharmaceutical composition
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
Claims (8)
2. Соединение формулы (I) по п.1 или его физиологически приемлемый сольват для применения в ветеринарии или в медицине человека.
3. Применение соединения формулы (I) по п.1 или его физиологически приемлемого сольвата для изготовления лекарства для лечения воспалительных и/или аллергических состояний.
4. Фармацевтическая композиция, содержащая соединение формулы (I) по п.1 или его физиологически приемлемый сольват, если требуется, в смеси с одним или более физиологически приемлемыми разбавителями или носителями.
5. Фармацевтическая аэрозольная композиция, содержащая соединение формулы (I) по п.1 или его физиологически приемлемый сольват и фторуглерод или водородсодержащий хлорфторуглерод в качестве пропеллента, возможно в комбинации с поверхностно-активным веществом и/или со-растворителем.
6. Фармацевтическая композиция по п.5, которая дополнительно содержит другой терапевтически активный агент.
7. Фармацевтическая композиция по п.6, в которой указанный другой терапевтически активный агент представляет собой агонист β2-адренорецепторов.
8. Способ лечения человека или животного с воспалительным и/или аллергическим состоянием, включающий введение указанному человеку или животному эффективного количества соединения формулы (I) по п.1 или его физиологически приемлемого сольвата.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0316290.6A GB0316290D0 (en) | 2003-07-11 | 2003-07-11 | Novel compounds |
GB0316290.6 | 2003-07-11 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2009112207/04A Division RU2009112207A (ru) | 2003-07-11 | 2009-04-03 | Конкретное глюкокортикостероидное соединение, обладающее противовоспалительной активностью |
Publications (2)
Publication Number | Publication Date |
---|---|
RU2005141226A true RU2005141226A (ru) | 2006-08-27 |
RU2359973C2 RU2359973C2 (ru) | 2009-06-27 |
Family
ID=27742019
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2005141226/04A RU2359973C2 (ru) | 2003-07-11 | 2004-07-09 | Конкретное глюкокортикостероидное соединение, обладающее противовоспалительной активностью |
RU2005141064/04A RU2348645C2 (ru) | 2003-07-11 | 2004-07-09 | Специфическое глюкокортикостероидное соединение, обладающее противовоспалительной активностью |
RU2009112207/04A RU2009112207A (ru) | 2003-07-11 | 2009-04-03 | Конкретное глюкокортикостероидное соединение, обладающее противовоспалительной активностью |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2005141064/04A RU2348645C2 (ru) | 2003-07-11 | 2004-07-09 | Специфическое глюкокортикостероидное соединение, обладающее противовоспалительной активностью |
RU2009112207/04A RU2009112207A (ru) | 2003-07-11 | 2009-04-03 | Конкретное глюкокортикостероидное соединение, обладающее противовоспалительной активностью |
Country Status (31)
Country | Link |
---|---|
US (6) | US7291609B2 (ru) |
EP (3) | EP1644397B1 (ru) |
JP (3) | JP4709751B2 (ru) |
KR (2) | KR101029207B1 (ru) |
CN (3) | CN102372756A (ru) |
AR (2) | AR045900A1 (ru) |
AT (1) | ATE467638T1 (ru) |
AU (2) | AU2004255854B2 (ru) |
BR (2) | BRPI0412526A (ru) |
CA (2) | CA2531911C (ru) |
CY (2) | CY1110149T1 (ru) |
DE (1) | DE602004027137D1 (ru) |
DK (2) | DK1644398T3 (ru) |
ES (3) | ES2343685T3 (ru) |
GB (1) | GB0316290D0 (ru) |
HK (2) | HK1089185A1 (ru) |
HR (2) | HRP20100359T1 (ru) |
IL (3) | IL172776A (ru) |
IS (3) | IS2909B (ru) |
MA (2) | MA27897A1 (ru) |
MX (2) | MXPA06000442A (ru) |
MY (2) | MY140987A (ru) |
NO (2) | NO333263B1 (ru) |
NZ (2) | NZ544577A (ru) |
PL (2) | PL1644397T3 (ru) |
PT (2) | PT1644398E (ru) |
RU (3) | RU2359973C2 (ru) |
SI (2) | SI1644397T1 (ru) |
TW (2) | TWI367888B (ru) |
WO (2) | WO2005005452A1 (ru) |
ZA (2) | ZA200600223B (ru) |
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