RS62471B1 - Metode, kompleti i uređaji za proširenje populacije ćelija - Google Patents
Metode, kompleti i uređaji za proširenje populacije ćelijaInfo
- Publication number
- RS62471B1 RS62471B1 RS20211143A RSP20211143A RS62471B1 RS 62471 B1 RS62471 B1 RS 62471B1 RS 20211143 A RS20211143 A RS 20211143A RS P20211143 A RSP20211143 A RS P20211143A RS 62471 B1 RS62471 B1 RS 62471B1
- Authority
- RS
- Serbia
- Prior art keywords
- kits
- population
- expanding
- cells
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/12—Purification
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/48—Automatic or computerized control
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0635—B lymphocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0646—Natural killers cells [NK], NKT cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5156—Animal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/51—B7 molecules, e.g. CD80, CD86, CD28 (ligand), CD152 (ligand)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/515—CD3, T-cell receptor complex
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/52—CD40, CD40-ligand (CD154)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2537/00—Supports and/or coatings for cell culture characterised by physical or chemical treatment
- C12N2537/10—Cross-linking
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Sustainable Development (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Computer Hardware Design (AREA)
- Toxicology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Physics & Mathematics (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461980506P | 2014-04-16 | 2014-04-16 | |
PCT/EP2015/058339 WO2015158868A2 (en) | 2014-04-16 | 2015-04-16 | Methods, kits and apparatus for expanding a population of cells |
EP15720620.2A EP3132247B1 (en) | 2014-04-16 | 2015-04-16 | Methods, kits and apparatus for expanding a population of cells |
Publications (1)
Publication Number | Publication Date |
---|---|
RS62471B1 true RS62471B1 (sr) | 2021-11-30 |
Family
ID=53052805
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RS20211143A RS62471B1 (sr) | 2014-04-16 | 2015-04-16 | Metode, kompleti i uređaji za proširenje populacije ćelija |
Country Status (26)
Country | Link |
---|---|
US (2) | US11274278B2 (sr) |
EP (2) | EP3988920A1 (sr) |
JP (3) | JP6696969B2 (sr) |
KR (1) | KR102459384B1 (sr) |
CN (3) | CN111961647A (sr) |
AU (2) | AU2015248786B2 (sr) |
BR (1) | BR112016024072B1 (sr) |
CA (2) | CA2945889C (sr) |
CY (1) | CY1124717T1 (sr) |
DK (1) | DK3132247T3 (sr) |
ES (1) | ES2892927T3 (sr) |
HR (1) | HRP20211430T1 (sr) |
HU (1) | HUE056852T2 (sr) |
IL (3) | IL293587B1 (sr) |
LT (1) | LT3132247T (sr) |
MX (2) | MX2016013493A (sr) |
MY (1) | MY184699A (sr) |
PH (2) | PH12016502017A1 (sr) |
PL (1) | PL3132247T3 (sr) |
PT (1) | PT3132247T (sr) |
RS (1) | RS62471B1 (sr) |
RU (2) | RU2735640C9 (sr) |
SA (3) | SA516380090B1 (sr) |
SG (2) | SG11201608557UA (sr) |
SI (1) | SI3132247T1 (sr) |
WO (1) | WO2015158868A2 (sr) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2817625A2 (en) | 2012-02-23 | 2014-12-31 | Stage Cell Therapeutics GmbH | Chromatographic isolation of cells and other complex biological materials |
EP3988920A1 (en) | 2014-04-16 | 2022-04-27 | Juno Therapeutics GmbH | Methods, kits and apparatus for expanding a population of cells |
KR20220136455A (ko) | 2014-04-23 | 2022-10-07 | 주노 쎄러퓨티크스 인코퍼레이티드 | 입양 치료용 면역 세포 집단의 단리, 배양 및 유전자 조작 방법 |
RU2761555C2 (ru) * | 2015-10-22 | 2021-12-09 | Джуно Терапьютикс Гмбх | Способы, наборы, средства и устройства для трансдукции |
MA45489A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés de culture de cellules, kits et appareil associés |
MA45488A (fr) * | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés, kits et appareil de culture de cellules |
EP3192810A1 (en) | 2016-01-14 | 2017-07-19 | Deutsches Krebsforschungszentrum | Psma binding antibody and uses thereof |
CN107129988A (zh) * | 2016-02-29 | 2017-09-05 | 广西医科大学 | 一种特异性结合cd3的核酸适配体及其筛选方法和应用 |
KR20230125857A (ko) * | 2016-06-02 | 2023-08-29 | 클로토 테라퓨틱스, 아이엔씨. | 치료학적 재조합 클로토 단백질 및 이를 수반하는 조성물및 방법 |
MA45784A (fr) | 2016-07-29 | 2019-06-05 | Juno Therapeutics Inc | Anticorps anti-idiotypes dirigés contre anti-cd19 anticorps |
US10294454B2 (en) | 2016-08-24 | 2019-05-21 | General Electric Company | Methods and kits for cell activation |
JP2019536461A (ja) * | 2016-12-05 | 2019-12-19 | ジュノー セラピューティクス インコーポレイテッド | 養子細胞療法のための操作細胞の産生 |
US20210047602A1 (en) * | 2017-03-31 | 2021-02-18 | Terumo Bct, Inc. | Cell expansion |
WO2018184028A2 (en) * | 2017-03-31 | 2018-10-04 | Terumo Bct, Inc. | Cell expansion |
US11624046B2 (en) * | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
TW201842335A (zh) | 2017-04-27 | 2018-12-01 | 德商朱諾醫療公司 | 寡聚粒子試劑及其使用方法 |
JP2021508443A (ja) * | 2017-12-15 | 2021-03-11 | アレタ・バイオセラピューティクス・インコーポレイテッドAleta Biotherapeutics Inc. | Cd19変異体 |
CN107904278B (zh) * | 2017-12-25 | 2021-07-20 | 北昊干细胞与再生医学研究院有限公司 | 检测药物对细胞增殖影响的方法 |
US11149244B2 (en) * | 2018-04-04 | 2021-10-19 | Southwest Research Institute | Three-dimensional bioreactor for T-cell activation and expansion for immunotherapy |
WO2019217512A1 (en) * | 2018-05-08 | 2019-11-14 | Life Technologies Corporation | Compositions and methods for culturing and expanding cells |
US20210206857A1 (en) * | 2018-05-21 | 2021-07-08 | Bioprocessia Technologies Llc | Multivalent protein complexes |
AU2019318560A1 (en) | 2018-08-09 | 2021-02-25 | Juno Therapeutics, Inc. | Processes for generating engineered cells and compositions thereof |
AU2019337394A1 (en) | 2018-09-11 | 2021-03-25 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Improved anti-FLT3 antigen binding proteins |
EP3623383A1 (en) | 2018-09-11 | 2020-03-18 | Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts | Improved bispecific flt3xcd3 antigen binding proteins |
AU2019346419B2 (en) * | 2018-09-24 | 2023-08-17 | Southwest Research Institute | Three-dimensional bioreactors |
SG11202104355SA (en) | 2018-10-31 | 2021-05-28 | Juno Therapeutics Gmbh | Methods for selection and stimulation of cells and apparatus for same |
KR20200132147A (ko) * | 2019-05-15 | 2020-11-25 | 의료법인 성광의료재단 | 자연 살해 세포의 배양용 조성물 및 이를 이용한 방법 |
JP7304649B2 (ja) * | 2019-05-24 | 2023-07-07 | ソル バイオ コーポレーション | スイッチ性付着反応を用いた親和分離システム及び方法 |
BR112021024404A2 (pt) * | 2019-06-07 | 2022-04-19 | Juno Therapeutics Inc | Cultura de célula t automatizada |
AU2020377043A1 (en) | 2019-10-30 | 2022-06-02 | Juno Therapeutics Gmbh | Cell selection and/or stimulation devices and methods of use |
EP3822288A1 (en) | 2019-11-18 | 2021-05-19 | Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts | Antibodies targeting, and other modulators of, the cd276 antigen, and uses thereof |
JP2023504740A (ja) | 2019-12-06 | 2023-02-06 | ジュノー セラピューティクス インコーポレイテッド | Bcma標的結合ドメインに対する抗イディオタイプ抗体ならびに関連する組成物および方法 |
JP2023504736A (ja) | 2019-12-06 | 2023-02-06 | ジュノー セラピューティクス インコーポレイテッド | Gprc5d標的結合ドメインに対する抗イディオタイプ抗体ならびに関連する組成物および方法 |
CA3163761C (en) | 2020-01-31 | 2023-07-11 | Herbert Stadler | Methods of isolating a biological entity |
AU2021219764A1 (en) | 2020-02-12 | 2022-09-01 | Juno Therapeutics, Inc. | BCMA-directed chimeric antigen receptor T cell compositions and methods and uses thereof |
US20230190798A1 (en) | 2020-02-12 | 2023-06-22 | Juno Therapeutics, Inc. | Cd19-directed chimeric antigen receptor t cell compositions and methods and uses thereof |
KR20230095918A (ko) | 2020-08-05 | 2023-06-29 | 주노 쎄러퓨티크스 인코퍼레이티드 | Ror1-표적 결합 도메인에 대한 항이디오타입 항체 및 관련 조성물 및 방법 |
WO2022098787A1 (en) | 2020-11-04 | 2022-05-12 | Juno Therapeutics, Inc. | Cells expressing a chimeric receptor from a modified invariant cd3 immunoglobulin superfamily chain locus and related polynucleotides and methods |
EP4263600A1 (en) | 2020-12-18 | 2023-10-25 | Century Therapeutics, Inc. | Chimeric antigen receptor systems with adaptable receptor specificity |
US20240168012A1 (en) | 2021-03-22 | 2024-05-23 | Juno Therapeutics, Inc. | Methods of determining potency of a therapeutic cell composition |
WO2022234009A2 (en) | 2021-05-06 | 2022-11-10 | Juno Therapeutics Gmbh | Methods for stimulating and transducing t cells |
EP4373920A1 (en) | 2021-07-19 | 2024-05-29 | Repairon Immuno GmbH | Method of producing a population of immune cells from pluripotent stem cells |
WO2023213969A1 (en) | 2022-05-05 | 2023-11-09 | Juno Therapeutics Gmbh | Viral-binding protein and related reagents, articles, and methods of use |
WO2024100604A1 (en) | 2022-11-09 | 2024-05-16 | Juno Therapeutics Gmbh | Methods for manufacturing engineered immune cells |
WO2024124132A1 (en) | 2022-12-09 | 2024-06-13 | Juno Therapeutics, Inc. | Machine learning methods for predicting cell phenotype using holographic imaging |
WO2024161021A1 (en) | 2023-02-03 | 2024-08-08 | Juno Therapeutics Gmbh | Methods for non-viral manufacturing of engineered immune cells |
US20240285762A1 (en) | 2023-02-28 | 2024-08-29 | Juno Therapeutics, Inc. | Cell therapy for treating systemic autoimmune diseases |
CN117448255A (zh) * | 2023-09-28 | 2024-01-26 | 深圳市龙华区人民医院 | S2饲养细胞、制备方法及其应用 |
Family Cites Families (83)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4361549A (en) | 1979-04-26 | 1982-11-30 | Ortho Pharmaceutical Corporation | Complement-fixing monoclonal antibody to human T cells, and methods of preparing same |
JP2624470B2 (ja) | 1984-10-02 | 1997-06-25 | バイオジェン インコーポレイテッド | ストレプトアビジン様ポリペプチドの製造 |
US4851341A (en) | 1986-12-19 | 1989-07-25 | Immunex Corporation | Immunoaffinity purification system |
US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
DE4237113B4 (de) | 1992-11-03 | 2006-10-12 | "Iba Gmbh" | Peptide und deren Fusionsproteine, Expressionsvektor und Verfahren zur Herstellung eines Fusionsproteins |
ES2240962T3 (es) | 1993-06-04 | 2005-10-16 | The United States Of America As Represented By The Secretary Of The Navy | Metodo para estimular selectivamente la proliferacion de celulas t. |
AU5132096A (en) | 1995-01-30 | 1996-08-21 | Terrapin Technologies, Inc. | Glubodies - multiplicities of proteins capable of binding a variety of small molecules |
WO1996024606A1 (en) | 1995-02-09 | 1996-08-15 | University Of Washington | Modified-affinity streptavidin |
US6022951A (en) | 1995-04-11 | 2000-02-08 | Univ Boston | Streptavidin mutants |
DE19641876B4 (de) | 1996-10-10 | 2011-09-29 | Iba Gmbh | Streptavidinmuteine |
AU6701498A (en) | 1997-03-14 | 1998-09-29 | Trustees Of Boston University | Multiflavor streptavidin |
US5985658A (en) | 1997-11-14 | 1999-11-16 | Health Research Incorporated | Calmodulin-based cell separation technique |
WO2000043551A1 (en) | 1999-01-26 | 2000-07-27 | Cornell Research Foundation, Inc. | Determining viral load in double negative t cells |
DK2332976T3 (da) * | 1999-02-03 | 2014-06-23 | Amgen Inc | Nye polypeptider, der er involveret ved et immunrespons |
AU759719B2 (en) | 1999-02-04 | 2003-04-17 | Pluristem Ltd. | Method and apparatus for maintenance and expansion of hemopoietic stem cells and/or progenitor cells |
DE19932688B4 (de) | 1999-07-13 | 2009-10-08 | Scil Proteins Gmbh | Design von Beta-Faltblatt-Proteinen des gamma-II-kristallins antikörperähnlichen |
US20030235908A1 (en) * | 2000-02-24 | 2003-12-25 | Xcyte Therapies, Inc. | Activation and expansion of cells |
US7572631B2 (en) | 2000-02-24 | 2009-08-11 | Invitrogen Corporation | Activation and expansion of T cells |
EP1227321A1 (en) | 2000-12-28 | 2002-07-31 | Institut für Bioanalytik GmbH | Reversible MHC multimer staining for functional purification of antigen-specific T cells |
DE10113776B4 (de) | 2001-03-21 | 2012-08-09 | "Iba Gmbh" | Isoliertes streptavidinbindendes, kompetitiv eluierbares Peptid, dieses umfassendes Fusionspeptid, dafür codierende Nukleinsäure, Expressionsvektor, Verfahren zur Herstellung eines rekombinanten Fusionsproteins und Verfahren zum Nachweis und/oder zur Gewinnung des Fusionsproteins |
WO2009003492A1 (en) | 2007-07-03 | 2009-01-08 | Dako Denmark A/S | Mhc multimers, methods for their generation, labeling and use |
WO2003029462A1 (en) | 2001-09-27 | 2003-04-10 | Pieris Proteolab Ag | Muteins of human neutrophil gelatinase-associated lipocalin and related proteins |
DE50307984D1 (de) | 2002-03-01 | 2007-09-27 | Volker A Erdmann | Streptavidin-Bindungspeptid |
US7754155B2 (en) | 2002-03-15 | 2010-07-13 | Ross Amelia A | Devices and methods for isolating target cells |
AU2003234194A1 (en) | 2002-04-23 | 2003-11-10 | Meir Strahilevitz | Methods and devices for targeting a site in a mammal and for removing species from a mammal |
FR2841905B1 (fr) | 2002-07-05 | 2004-09-03 | Centre Nat Rech Scient | Fragments fab mutants de l'anticorps anti-cd4 chimere 13b8.2 et leurs applications |
WO2004029221A2 (en) | 2002-09-27 | 2004-04-08 | The General Hospital Corporation | Microfluidic device for cell separation and uses thereof |
EP1641911A2 (en) | 2003-05-02 | 2006-04-05 | Insception Bioscience, Inc. | Apparatus and methods for amplification of blood stem cell numbers |
WO2004104185A1 (en) | 2003-05-08 | 2004-12-02 | Xcyte Therapies, Inc. | Generation and isolation of antigen-specific t cells |
CN1902491A (zh) | 2003-11-20 | 2007-01-24 | 瑞典生物传感器应用股份公司 | 至少两种不同的、特异于预定抗原的抗体混合物和该混合物的用途 |
SE0400181D0 (sv) | 2004-01-29 | 2004-01-29 | Gyros Ab | Segmented porous and preloaded microscale devices |
DK1766400T3 (da) | 2004-06-03 | 2009-07-20 | Meso Scale Technologies Llc | Fremgangsmåde til at udföre fuldblodsanalyser |
ATE536552T1 (de) | 2004-10-15 | 2011-12-15 | Danisco Us Inc | Kompetitven differential screening |
WO2006058226A2 (en) * | 2004-11-24 | 2006-06-01 | The Trustees Of Boston University | Modified dimeric streptavidins and uses thereof |
US20060252087A1 (en) | 2005-01-18 | 2006-11-09 | Biocept, Inc. | Recovery of rare cells using a microchannel apparatus with patterned posts |
US7704708B2 (en) * | 2006-02-13 | 2010-04-27 | Uti Limited Partnership | Monomeric streptavidin muteins |
US7855057B2 (en) | 2006-03-23 | 2010-12-21 | Millipore Corporation | Protein splice variant/isoform discrimination and quantitative measurements thereof |
US20090208471A1 (en) | 2006-04-07 | 2009-08-20 | Yun Theodore J | Isolation and Use of Human Regulatory T Cells |
US20080085532A1 (en) | 2006-09-18 | 2008-04-10 | Jorn Gorlach | Method for determining the immune status of a subject |
CN102850433B (zh) | 2006-10-17 | 2016-03-02 | 肿瘤疗法科学股份有限公司 | 用于表达mphosph1或depdc1多肽的癌症的肽疫苗 |
KR101396673B1 (ko) | 2006-11-02 | 2014-05-16 | 교와 메덱스 가부시키가이샤 | 측정 대상 성분의 면역 측정법 |
AU2007353319A1 (en) | 2006-11-15 | 2008-11-20 | Invitrogen Dynal As | Methods for reversibly binding a biotin compound to a support |
US20080131415A1 (en) | 2006-11-30 | 2008-06-05 | Riddell Stanley R | Adoptive transfer of cd8 + t cell clones derived from central memory cells |
CN101226118B (zh) | 2007-01-19 | 2010-06-16 | 中国医学科学院肿瘤研究所 | 一种兼容免疫荧光分析的细胞化学染色方法及其用途 |
US8709980B2 (en) * | 2007-03-26 | 2014-04-29 | Celexion, Llc | Cell surface display, screening and production of proteins of interest |
US8735330B2 (en) | 2007-08-20 | 2014-05-27 | Nextera As | pVII phage display |
EP3338895B1 (en) | 2007-12-07 | 2022-08-10 | Miltenyi Biotec B.V. & Co. KG | Sample processing systems and methods |
BR122018069446B8 (pt) | 2008-01-18 | 2021-07-27 | Harvard College | método in vitro para detectar a presença de um célula de câncer em um indivíduo |
JP2011510653A (ja) | 2008-01-29 | 2011-04-07 | フレッド ハッチンソン キャンサー リサーチ センター | CD161hiおよび/またはIL18Rahiであり、迅速な薬剤流出能力を有するCD8+T細胞の同定 |
CN101446576B (zh) | 2008-12-29 | 2011-06-22 | 江苏省苏微微生物研究有限公司 | 一种微囊藻毒素-lr单抗免疫亲和柱的制备和使用方法 |
WO2010080032A2 (en) | 2009-01-09 | 2010-07-15 | Stichting Het Nederlands Kanker Instituut | Bead-assisted viral transduction |
US20110070581A1 (en) | 2009-04-27 | 2011-03-24 | Amit Gupta | Separation of Leukocytes |
WO2011053971A2 (en) * | 2009-11-02 | 2011-05-05 | Fina Biosolutions, Llc | Method for enhancing the sensitivity of antibody based assays |
US20120321665A1 (en) * | 2009-12-14 | 2012-12-20 | Benaroya Research Institute At Virginia Mason | Compositions and methods for treating airway inflammatory diseases |
EP2363501A1 (en) | 2010-03-02 | 2011-09-07 | Universitätsklinikum Hamburg-Eppendorf | Method for isolating target cells |
EP3376225A1 (en) | 2010-08-06 | 2018-09-19 | Ludwig-Maximilians-Universität München | Identification of t cell target antigens |
WO2012058627A2 (en) | 2010-10-29 | 2012-05-03 | Miqin Zhang | Pre-targeted nanoparticle system and method for labeling biological particles |
CN106074601A (zh) | 2011-03-23 | 2016-11-09 | 弗雷德哈钦森癌症研究中心 | 用于细胞免疫治疗的方法和组合物 |
SI2734538T1 (sl) * | 2011-07-18 | 2018-09-28 | Iba Gmbh | Postopek za reverzibilno obarvanje tarčne celice |
US9353161B2 (en) | 2011-09-13 | 2016-05-31 | Uti Limited Partnership | Streptavidin mutein exhibiting reversible binding for biotin and streptavidin binding peptide tagged proteins |
EP2817625A2 (en) | 2012-02-23 | 2014-12-31 | Stage Cell Therapeutics GmbH | Chromatographic isolation of cells and other complex biological materials |
UA114108C2 (uk) * | 2012-07-10 | 2017-04-25 | Борд Оф Ріджентс, Дзе Юніверсіті Оф Техас Сістем | Моноклональне антитіло для застосування в діагностиці і терапії злоякісних пухлин і аутоімунного захворювання |
IN2014DN11156A (sr) | 2012-07-13 | 2015-10-02 | Univ Pennsylvania | |
RU2700765C2 (ru) | 2012-08-20 | 2019-09-19 | Фред Хатчинсон Кансэр Рисёч Сентер | Способ и композиции для клеточной иммунотерапии |
US10065996B2 (en) | 2012-11-16 | 2018-09-04 | Iba Gmbh | Streptavidin muteins and methods of using them |
CN103305464B (zh) | 2013-06-05 | 2015-04-15 | 南昌大学 | 直接分离cd4+和cd8+淋巴细胞的方法 |
US9698876B2 (en) | 2013-07-23 | 2017-07-04 | Telefonaktiebolaget Lm Ericsson (Publ) | Transmission mode allocation in LTE networks |
KR20230007559A (ko) | 2013-12-20 | 2023-01-12 | 프레드 허친슨 캔서 센터 | 태그된 키메라 이펙터 분자 및 그의 리셉터 |
SG10202109752XA (en) | 2014-04-07 | 2021-10-28 | Novartis Ag | Treatment of cancer using anti-cd19 chimeric antigen receptor |
EP3988920A1 (en) | 2014-04-16 | 2022-04-27 | Juno Therapeutics GmbH | Methods, kits and apparatus for expanding a population of cells |
KR20220136455A (ko) | 2014-04-23 | 2022-10-07 | 주노 쎄러퓨티크스 인코퍼레이티드 | 입양 치료용 면역 세포 집단의 단리, 배양 및 유전자 조작 방법 |
US10131876B2 (en) | 2014-04-24 | 2018-11-20 | Miltenyi Biotec Gmbh | Method for automated generation of genetically modified T cells |
CN110819595A (zh) | 2014-04-25 | 2020-02-21 | 蓝鸟生物公司 | 制备过继性细胞疗法的改善方法 |
CA2945414C (en) * | 2014-04-30 | 2023-05-09 | Iba Gmbh | Method of isolating a target cell |
DK3280729T3 (da) | 2015-04-08 | 2022-07-25 | Novartis Ag | Cd20-behandlinger, cd22-behandlinger og kombinationsbehandlinger med en cd19-kimær antigenreceptor (car)-udtrykkende celle |
WO2016166568A1 (en) | 2015-04-16 | 2016-10-20 | Juno Therapeutics Gmbh | Methods, kits and apparatus for expanding a population of cells |
RU2761555C2 (ru) | 2015-10-22 | 2021-12-09 | Джуно Терапьютикс Гмбх | Способы, наборы, средства и устройства для трансдукции |
MA45488A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés, kits et appareil de culture de cellules |
MA45489A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés de culture de cellules, kits et appareil associés |
MA43380A (fr) | 2015-12-03 | 2018-10-10 | Juno Therapeutics Inc | Récepteurs chimériques modifiés et compositions et procédés associés |
TW201842335A (zh) | 2017-04-27 | 2018-12-01 | 德商朱諾醫療公司 | 寡聚粒子試劑及其使用方法 |
AU2019318560A1 (en) | 2018-08-09 | 2021-02-25 | Juno Therapeutics, Inc. | Processes for generating engineered cells and compositions thereof |
SG11202104355SA (en) | 2018-10-31 | 2021-05-28 | Juno Therapeutics Gmbh | Methods for selection and stimulation of cells and apparatus for same |
-
2015
- 2015-04-16 EP EP21191440.3A patent/EP3988920A1/en active Pending
- 2015-04-16 SG SG11201608557UA patent/SG11201608557UA/en unknown
- 2015-04-16 MX MX2016013493A patent/MX2016013493A/es unknown
- 2015-04-16 US US15/304,045 patent/US11274278B2/en active Active
- 2015-04-16 KR KR1020167031915A patent/KR102459384B1/ko active IP Right Grant
- 2015-04-16 CN CN202010423347.2A patent/CN111961647A/zh active Pending
- 2015-04-16 CA CA2945889A patent/CA2945889C/en active Active
- 2015-04-16 CN CN201580032543.4A patent/CN106414724A/zh active Pending
- 2015-04-16 IL IL293587A patent/IL293587B1/en unknown
- 2015-04-16 DK DK15720620.2T patent/DK3132247T3/da active
- 2015-04-16 BR BR112016024072-3A patent/BR112016024072B1/pt active IP Right Grant
- 2015-04-16 SG SG10201808491UA patent/SG10201808491UA/en unknown
- 2015-04-16 ES ES15720620T patent/ES2892927T3/es active Active
- 2015-04-16 WO PCT/EP2015/058339 patent/WO2015158868A2/en active Application Filing
- 2015-04-16 RU RU2016144724A patent/RU2735640C9/ru active
- 2015-04-16 EP EP15720620.2A patent/EP3132247B1/en active Active
- 2015-04-16 MY MYPI2016703777A patent/MY184699A/en unknown
- 2015-04-16 LT LTEPPCT/EP2015/058339T patent/LT3132247T/lt unknown
- 2015-04-16 JP JP2017505717A patent/JP6696969B2/ja active Active
- 2015-04-16 HU HUE15720620A patent/HUE056852T2/hu unknown
- 2015-04-16 RS RS20211143A patent/RS62471B1/sr unknown
- 2015-04-16 CN CN202310417528.8A patent/CN116656605A/zh active Pending
- 2015-04-16 IL IL280738A patent/IL280738B/en unknown
- 2015-04-16 PT PT157206202T patent/PT3132247T/pt unknown
- 2015-04-16 CA CA3176848A patent/CA3176848A1/en active Pending
- 2015-04-16 SI SI201531727T patent/SI3132247T1/sl unknown
- 2015-04-16 RU RU2020133435A patent/RU2020133435A/ru unknown
- 2015-04-16 AU AU2015248786A patent/AU2015248786B2/en active Active
- 2015-04-16 PL PL15720620T patent/PL3132247T3/pl unknown
-
2016
- 2016-10-11 PH PH12016502017A patent/PH12016502017A1/en unknown
- 2016-10-13 MX MX2020014089A patent/MX2020014089A/es unknown
- 2016-10-13 IL IL248360A patent/IL248360B/en active IP Right Grant
- 2016-10-16 SA SA516380090A patent/SA516380090B1/ar unknown
- 2016-10-16 SA SA521421882A patent/SA521421882B1/ar unknown
- 2016-10-16 SA SA520412247A patent/SA520412247B1/ar unknown
-
2020
- 2020-04-23 JP JP2020076705A patent/JP2020124210A/ja active Pending
- 2020-07-01 PH PH12020551028A patent/PH12020551028A1/en unknown
-
2021
- 2021-09-13 HR HRP20211430TT patent/HRP20211430T1/hr unknown
- 2021-11-02 CY CY20211100943T patent/CY1124717T1/el unknown
-
2022
- 2022-01-27 AU AU2022200527A patent/AU2022200527A1/en active Pending
- 2022-03-11 US US17/693,292 patent/US20220195388A1/en active Pending
-
2023
- 2023-02-20 JP JP2023024443A patent/JP2023062124A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL280738A (en) | Methods, kits and device for increasing cell populations | |
HK1258931A1 (zh) | 培養細胞的方法及用於該方法的試劑盒和設備 | |
HK1258933A1 (zh) | 培養細胞的方法及用於該方法的試劑盒和設備 | |
IL251261B (en) | Reagents and methods for the identification, enrichment and/or expansion of antigen-specific T-cells | |
EP3090579A4 (en) | DEVICE, NETWORK AND METHOD FOR CELL DISCOVERY | |
EP3164482C0 (en) | DEVICE AND METHOD FOR THE RAPID OPTIMIZATION OF CELLULAR ELECTROPORATION | |
EP3163849A4 (en) | Method and apparatus for selecting main microphone | |
PL3172567T3 (pl) | Sposoby i zestawy do monitorowania nefropatii błoniastej | |
EP3140833A4 (en) | Apparatuses and methods for performing multiple memory operations | |
EP3091786A4 (en) | Apparatus, method and system for cell selection | |
EP3105315A4 (en) | Kits and methods for reprograming non-hepatocyte cells into hepatocyte cells | |
EP3244656A4 (en) | Cell selection method and apparatus | |
EP3196292A4 (en) | Cell culture apparatus and method | |
SG11201701562WA (en) | Cell trapping method, method for producing specific cell-trapping device, and method for producing specific cell-containing solution | |
EP3107996A4 (en) | Tscm cells and methods for use | |
GB201405130D0 (en) | Electrochemical method and apparatus | |
EP3229515A4 (en) | Method and apparatus for indicating cell splitting pattern | |
HK1217351A1 (zh) | 種細胞裂解方法 | |
HK1243960A1 (zh) | T細胞群的改變方法 | |
EP3156080A4 (en) | Cell structure and method for producing cell structure | |
EP3192295A4 (en) | Method and arrangement for cell combination | |
EP3304961A4 (en) | Method and apparatus for cell configuration | |
EP3155085A4 (en) | Method and apparatus for making soap | |
GB201417372D0 (en) | Methods and kits | |
EP3165602A4 (en) | Method for producing b cell population |