ATE536552T1 - Kompetitven differential screening - Google Patents

Kompetitven differential screening

Info

Publication number
ATE536552T1
ATE536552T1 AT05810831T AT05810831T ATE536552T1 AT E536552 T1 ATE536552 T1 AT E536552T1 AT 05810831 T AT05810831 T AT 05810831T AT 05810831 T AT05810831 T AT 05810831T AT E536552 T1 ATE536552 T1 AT E536552T1
Authority
AT
Austria
Prior art keywords
binders
present
competitive
differential screening
provides methods
Prior art date
Application number
AT05810831T
Other languages
English (en)
Inventor
Anthony Day
David Estell
Paul Jedzejewski
Christopher Murray
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Application granted granted Critical
Publication of ATE536552T1 publication Critical patent/ATE536552T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT05810831T 2004-10-15 2005-10-14 Kompetitven differential screening ATE536552T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61956204P 2004-10-15 2004-10-15
US63290804P 2004-12-03 2004-12-03
PCT/US2005/037004 WO2006044650A2 (en) 2004-10-15 2005-10-14 Competitive differential screening

Publications (1)

Publication Number Publication Date
ATE536552T1 true ATE536552T1 (de) 2011-12-15

Family

ID=36203551

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05810831T ATE536552T1 (de) 2004-10-15 2005-10-14 Kompetitven differential screening

Country Status (7)

Country Link
US (2) US20110098184A1 (de)
EP (1) EP1800136B1 (de)
JP (1) JP5255841B2 (de)
CN (1) CN101044405B (de)
AT (1) ATE536552T1 (de)
DK (1) DK1800136T3 (de)
WO (1) WO2006044650A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008292474A (ja) * 2007-04-27 2008-12-04 Nationa Hospital Organization 成人ｔ細胞白血病発症リスク判定方法
IN2012DN06589A (de) 2010-01-19 2015-10-23 Harvard College
CA2842321C (en) 2011-07-18 2022-05-03 President And Fellows Of Harvard College Engineered microbe-targeting molecules and uses thereof
SG10201606970UA (en) 2012-02-23 2016-10-28 Juno Therapeutics Gmbh Chromatographic isolation of cells and other complex biological materials
CN103012561B (zh) * 2012-12-26 2014-06-25 首都医科大学附属北京朝阳医院 一种肿瘤靶向诊断用小肽
EP2976642A4 (de) * 2013-03-15 2016-09-21 Harvard College Verfahren und zusammensetzungen zur verbesserung der erkennung und/oder aufnahme einer zieleinheit
JP6649250B2 (ja) 2013-05-21 2020-02-19 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 操作されたヘム結合性構成物およびその使用
EP3083658B1 (de) 2013-12-18 2019-05-08 President and Fellows of Harvard College Detektion gram-positiver bakterien mit crp
ES2892927T3 (es) 2014-04-16 2022-02-07 Juno Therapeutics Gmbh Métodos, kits y aparatos para expandir una población de células
MA51794A (fr) 2014-04-23 2020-05-06 Juno Therapeutics Inc Procédés d'isolation, de culture et de modification génétique de populations de cellules immunitaires pour thérapie adoptive
EP3763378A1 (de) 2015-08-06 2021-01-13 President and Fellows of Harvard College Verbesserte mikrobenbindende moleküle und verwendungen davon
MA45489A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés de culture de cellules, kits et appareil associés
RU2021134624A (ru) 2015-10-22 2022-03-15 Джуно Терапьютикс Гмбх Способы, наборы, средства и устройства для трансдукции
MA45488A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés, kits et appareil de culture de cellules
ES3038614T3 (en) 2017-04-27 2025-10-14 Juno Therapeutics Inc Oligomeric particle reagents and methods of use thereof
MX2021001523A (es) 2018-08-09 2021-05-27 Juno Therapeutics Inc Procesos para generar células modificadas y composiciones de las mismas.
WO2020089343A1 (en) 2018-10-31 2020-05-07 Juno Therapeutics Gmbh Methods for selection and stimulation of cells and apparatus for same

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4458066A (en) * 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5061620A (en) * 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell
US5965132A (en) * 1992-03-05 1999-10-12 Board Of Regents, The University Of Texas System Methods and compositions for targeting the vasculature of solid tumors
US5677136A (en) * 1994-11-14 1997-10-14 Systemix, Inc. Methods of obtaining compositions enriched for hematopoietic stem cells, compositions derived therefrom and methods of use thereof
GB9719176D0 (en) * 1997-09-09 1997-11-12 Glaxo Group Ltd New therapeutic method
EP1173602A1 (de) * 1999-04-12 2002-01-23 The Regents Of The University Of California Ecotin derivate
AU4643300A (en) * 1999-04-12 2000-11-14 Regents Of The University Of California, The Engineering ecotin-variant modulators of serine proteases
DE602004030212D1 (de) * 2003-01-16 2011-01-05 Caprotec Bioanalytics Gmbh Verfahren zur identifizierung von auf arzneimittel nicht-zielgerichteten proteinen
JP2006514299A (ja) * 2003-10-27 2006-04-27 センス プロテオミック リミテッド 酵素アレイ及びアッセイ
EP1692160B1 (de) * 2003-11-06 2010-10-27 Danisco US Inc. Fgf-5-bindende und geträgerte peptide

Also Published As

Publication number Publication date
US20130029850A1 (en) 2013-01-31
US20110098184A1 (en) 2011-04-28
JP5255841B2 (ja) 2013-08-07
WO2006044650A9 (en) 2006-08-31
WO2006044650A2 (en) 2006-04-27
EP1800136B1 (de) 2011-12-07
EP1800136A2 (de) 2007-06-27
WO2006044650A3 (en) 2006-12-14
CN101044405B (zh) 2015-06-10
JP2008517275A (ja) 2008-05-22
DK1800136T3 (da) 2012-03-26
CN101044405A (zh) 2007-09-26

Similar Documents

Publication Publication Date Title
DK1800136T3 (da) Kompetitiv differentiel screening
WO2006105152A3 (en) Amnion-derived cell compositions, methods of making and uses thereof
ATE514755T1 (de) Fluoreszenzfarbstoffe zur verwendung bei der glukoseerfassung
PH12016501691A1 (en) Antibodies to matrix metalloproteinase 9
EP3255063A3 (de) Antikörper gegen matrix-metalloproteinase-9
SG170793A1 (en) Anti-mn antibodies and methods of using same
WO2006137941A3 (en) Methods and compositions involving mirna and mirna inhibitor molecules
ATE513833T1 (de) Thienopyridinverbindungen und verfahren zu ihrer verwendung
IL178761A0 (en) Antibodies and molecules derived therefrom that bind to steap-1 proteins
WO2009111508A3 (en) Metalloproteinase 9 and metalloproteinase 2 binding proteins
WO2008151819A3 (en) Treatment of tumors using specific anti-l1 antibody
WO2007079218A3 (en) Metalloproteinase binding proteins
EA201390638A8 (ru) Обогащение и идентификация фетальных клеток в материнской крови и лиганды для такого применения
ATE554390T1 (de) Verfahren zur gewinnung von antikörpern
EA200901421A1 (ru) Антитела к il-25
WO2009055074A8 (en) Erbb2 binding proteins and use thereof
MX2007004247A (es) Agentes de aglutinacion especifica a angiopoyetina-2.
WO2005103698A3 (en) Methods and antibodies for nitrofuran detection
ATE550354T1 (de) Humane ringspezifische bnp-antikörper
WO2005087951A3 (en) Reagents, methods and kits for use in deactivating nucleic acids
AU2021269176A8 (en) Single domain antibodies binding to SARS-CoV-2 spike protein
WO2006034278A3 (en) Methods and compositions for detecting cancer using components of the u2 spliceosomal particle
IL179332A0 (en) Antibodies and related molecules that bind to psca proteins
ATE495243T1 (de) Verfahren zur herstellung von hochempfindlichen endonukleasen, neuartige zubereitungen von nukleasen und ihre verwendung
WO2007067984A3 (en) Neutralizing antibodies against primate psgl-1 and uses therefor