RS51927B - Jedinjenja pirido (2,3-d)pirimidinona i njihova upotreba kao inhibitora p13 - Google Patents

Jedinjenja pirido (2,3-d)pirimidinona i njihova upotreba kao inhibitora p13

Info

Publication number
RS51927B
RS51927B RS20110379A RSP20110379A RS51927B RS 51927 B RS51927 B RS 51927B RS 20110379 A RS20110379 A RS 20110379A RS P20110379 A RSP20110379 A RS P20110379A RS 51927 B RS51927 B RS 51927B
Authority
RS
Serbia
Prior art keywords
group
methyl
amino
pyrimidin
trans
Prior art date
Application number
RS20110379A
Other languages
English (en)
Serbian (sr)
Inventor
Mitchell David Nambu
Hengmiao Cheng
Mason Alan Pairish
Dilip Bhumralkar
Jacqui Elizabet Hoffman
Mary Catherine Johnson
Robert Steven Kania
Phuong Thi Quy Le
Michael Bruno Plewe
Klaus Ruprecht Dress
Khanh Tuan Tran
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of RS51927B publication Critical patent/RS51927B/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyridine Compounds (AREA)
RS20110379A 2006-09-15 2007-09-03 Jedinjenja pirido (2,3-d)pirimidinona i njihova upotreba kao inhibitora p13 RS51927B (sr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US84506506P 2006-09-15 2006-09-15
US94785207P 2007-07-03 2007-07-03
US95262807P 2007-07-30 2007-07-30
PCT/IB2007/002578 WO2008032162A1 (en) 2006-09-15 2007-09-03 Pyrido (2, 3-d) pyrimidin0ne compounds and their use as pi3 inhibitors

Publications (1)

Publication Number Publication Date
RS51927B true RS51927B (sr) 2012-02-29

Family

ID=38859750

Family Applications (2)

Application Number Title Priority Date Filing Date
RS20110379A RS51927B (sr) 2006-09-15 2007-09-03 Jedinjenja pirido (2,3-d)pirimidinona i njihova upotreba kao inhibitora p13
RSP-2009/0104A RS20090104A (sr) 2006-09-15 2007-09-03 Jedinjenja pirido (2,3-d) pirimidinona i njihova upotreba kao inhibitora p13

Family Applications After (1)

Application Number Title Priority Date Filing Date
RSP-2009/0104A RS20090104A (sr) 2006-09-15 2007-09-03 Jedinjenja pirido (2,3-d) pirimidinona i njihova upotreba kao inhibitora p13

Country Status (41)

Country Link
US (3) US7696213B2 (enExample)
EP (1) EP2074122B9 (enExample)
JP (1) JP4718637B2 (enExample)
KR (1) KR101099926B1 (enExample)
CN (1) CN101573358B (enExample)
AP (1) AP2710A (enExample)
AR (1) AR062785A1 (enExample)
AT (1) ATE514695T1 (enExample)
AU (1) AU2007297212B8 (enExample)
BR (1) BRPI0716749B8 (enExample)
CA (1) CA2663401C (enExample)
CL (1) CL2007002682A1 (enExample)
CR (1) CR10662A (enExample)
CU (1) CU23783B7 (enExample)
CY (1) CY1111911T1 (enExample)
DK (1) DK2074122T5 (enExample)
DO (1) DOP2009000039A (enExample)
EA (1) EA016388B1 (enExample)
ES (1) ES2366489T3 (enExample)
GE (1) GEP20115306B (enExample)
GT (1) GT200700077A (enExample)
HN (1) HN2007000267A (enExample)
HR (1) HRP20110621T2 (enExample)
IL (1) IL197243A (enExample)
MA (1) MA30709B1 (enExample)
ME (1) MEP8009A (enExample)
MX (1) MX2009002927A (enExample)
MY (1) MY146420A (enExample)
NI (1) NI200900032A (enExample)
NO (1) NO342357B1 (enExample)
NZ (1) NZ575167A (enExample)
PE (1) PE20080670A1 (enExample)
PL (1) PL2074122T3 (enExample)
PT (1) PT2074122E (enExample)
RS (2) RS51927B (enExample)
SI (1) SI2074122T1 (enExample)
TN (1) TN2009000085A1 (enExample)
TW (1) TWI334353B (enExample)
UY (1) UY30588A1 (enExample)
WO (1) WO2008032162A1 (enExample)
ZA (1) ZA200901477B (enExample)

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HUE047477T2 (hu) 2015-06-04 2020-04-28 Pfizer Palbociclib szilárd dózisformái
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JP2019519593A (ja) 2016-07-06 2019-07-11 ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・ミシガンＴｈｅ Ｒｅｇｅｎｔｓ Ｏｆ Ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｍｉｃｈｉｇａｎ ＭＥＫ／ＰＩ３Ｋ及びｍＴＯＲ／ＭＥＫ／ＰＩ３Ｋ生物学的経路の多官能性阻害剤、並びに同多官能性阻害剤を用いた治療方法
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TW202134234A (zh) 2019-12-05 2021-09-16 美商奈維特製藥公司 雷帕黴素類似物及其用途
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AP2009004790A0 (en) 2009-04-30
AU2007297212A1 (en) 2008-03-20
IL197243A0 (en) 2009-12-24
MY146420A (en) 2012-08-15
BRPI0716749B8 (pt) 2021-05-25
ATE514695T1 (de) 2011-07-15
KR20090040389A (ko) 2009-04-23
HK1138589A1 (en) 2010-08-27
CA2663401A1 (en) 2008-03-20
ZA200901477B (en) 2010-07-28
GEP20115306B (enExample) 2011-10-10
GT200700077A (es) 2009-08-03
TWI334353B (en) 2010-12-11
PL2074122T3 (pl) 2011-10-31
CN101573358A (zh) 2009-11-04
NO20091141L (no) 2009-03-31
CU20090040A7 (es) 2011-07-11
DK2074122T3 (da) 2011-08-15
ES2366489T9 (es) 2013-12-27
MX2009002927A (es) 2009-03-31
WO2008032162A8 (en) 2009-03-26
US8273755B2 (en) 2012-09-25
CU23783B7 (es) 2012-02-15
AR062785A1 (es) 2008-12-03
MEP8009A (en) 2011-12-20
TN2009000085A1 (fr) 2010-08-19
JP2010503653A (ja) 2010-02-04
US20120309775A1 (en) 2012-12-06
AU2007297212B2 (en) 2011-04-14
AP2710A (en) 2013-07-30
KR101099926B1 (ko) 2011-12-28
EA016388B1 (ru) 2012-04-30
US7696213B2 (en) 2010-04-13
DOP2009000039A (es) 2015-12-15
DK2074122T5 (da) 2014-03-17
JP4718637B2 (ja) 2011-07-06
NZ575167A (en) 2010-10-29
US20100137279A1 (en) 2010-06-03
EP2074122B9 (en) 2013-09-11
SI2074122T1 (sl) 2011-10-28
US20080090801A1 (en) 2008-04-17
NI200900032A (es) 2010-05-14
EP2074122A1 (en) 2009-07-01
WO2008032162A1 (en) 2008-03-20
CL2007002682A1 (es) 2008-04-04
EA200970207A1 (ru) 2009-08-28
PE20080670A1 (es) 2008-06-14
CN101573358B (zh) 2012-05-30
RS20090104A (sr) 2010-06-30
CY1111911T1 (el) 2015-11-04
CR10662A (es) 2009-04-17
HN2007000267A (es) 2011-02-25
IL197243A (en) 2013-07-31
BRPI0716749B1 (pt) 2020-10-06
MA30709B1 (fr) 2009-09-01
UY30588A1 (es) 2008-05-02
AU2007297212B8 (en) 2011-04-28
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CA2663401C (en) 2011-07-12
NO342357B1 (no) 2018-05-14
TW200820972A (en) 2008-05-16
HRP20110621T2 (hr) 2013-12-06
PT2074122E (pt) 2011-08-24
HRP20110621T1 (hr) 2011-09-30
ES2366489T3 (es) 2011-10-20
BRPI0716749A2 (pt) 2014-02-18
EP2074122B1 (en) 2011-06-29

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