AP2710A - Pyrido (2, 3-D) Pyrimidinone compounds and their use as P13 inhibitors - Google Patents

Pyrido (2, 3-D) Pyrimidinone compounds and their use as P13 inhibitors

Info

Publication number
AP2710A
AP2710A AP2009004790A AP2009004790A AP2710A AP 2710 A AP2710 A AP 2710A AP 2009004790 A AP2009004790 A AP 2009004790A AP 2009004790 A AP2009004790 A AP 2009004790A AP 2710 A AP2710 A AP 2710A
Authority
AP
ARIPO
Prior art keywords
pyrido
inhibitors
pyrimidinone compounds
pyrimidinone
compounds
Prior art date
Application number
AP2009004790A
Other languages
English (en)
Other versions
AP2009004790A0 (en
Inventor
Dilip Bhumralkar
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AP2009004790A0 publication Critical patent/AP2009004790A0/xx
Application granted granted Critical
Publication of AP2710A publication Critical patent/AP2710A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AP2009004790A 2006-09-15 2007-09-03 Pyrido (2, 3-D) Pyrimidinone compounds and their use as P13 inhibitors AP2710A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US84506506P 2006-09-15 2006-09-15
US94785207P 2007-07-03 2007-07-03
US95262807P 2007-07-30 2007-07-30
PCT/IB2007/002578 WO2008032162A1 (en) 2006-09-15 2007-09-03 Pyrido (2, 3-d) pyrimidin0ne compounds and their use as pi3 inhibitors

Publications (2)

Publication Number Publication Date
AP2009004790A0 AP2009004790A0 (en) 2009-04-30
AP2710A true AP2710A (en) 2013-07-30

Family

ID=38859750

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2009004790A AP2710A (en) 2006-09-15 2007-09-03 Pyrido (2, 3-D) Pyrimidinone compounds and their use as P13 inhibitors

Country Status (42)

Country Link
US (3) US7696213B2 (xx)
EP (1) EP2074122B9 (xx)
JP (1) JP4718637B2 (xx)
KR (1) KR101099926B1 (xx)
CN (1) CN101573358B (xx)
AP (1) AP2710A (xx)
AR (1) AR062785A1 (xx)
AT (1) ATE514695T1 (xx)
AU (1) AU2007297212B8 (xx)
BR (1) BRPI0716749B8 (xx)
CA (1) CA2663401C (xx)
CL (1) CL2007002682A1 (xx)
CR (1) CR10662A (xx)
CU (1) CU23783B7 (xx)
CY (1) CY1111911T1 (xx)
DK (1) DK2074122T5 (xx)
DO (1) DOP2009000039A (xx)
EA (1) EA016388B1 (xx)
ES (1) ES2366489T3 (xx)
GE (1) GEP20115306B (xx)
GT (1) GT200700077A (xx)
HK (1) HK1138589A1 (xx)
HN (1) HN2007000267A (xx)
HR (1) HRP20110621T2 (xx)
IL (1) IL197243A (xx)
MA (1) MA30709B1 (xx)
ME (1) MEP8009A (xx)
MX (1) MX2009002927A (xx)
MY (1) MY146420A (xx)
NI (1) NI200900032A (xx)
NO (1) NO342357B1 (xx)
NZ (1) NZ575167A (xx)
PE (1) PE20080670A1 (xx)
PL (1) PL2074122T3 (xx)
PT (1) PT2074122E (xx)
RS (2) RS51927B (xx)
SI (1) SI2074122T1 (xx)
TN (1) TN2009000085A1 (xx)
TW (1) TWI334353B (xx)
UY (1) UY30588A1 (xx)
WO (1) WO2008032162A1 (xx)
ZA (1) ZA200901477B (xx)

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EP3636283A1 (en) 2015-06-04 2020-04-15 Pfizer Inc Solid dosage forms of palbociclib
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
WO2018009638A1 (en) 2016-07-06 2018-01-11 The Regents Of The University Of Michigan MULTIFUNCTIONAL INHIBITORS OF MEK/PI3K AND mTOR/MEK/PI3K BIOLOGICAL PATHWAYS AND THERAPEUTIC METHODS USING THE SAME
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IL302807A (en) 2020-11-18 2023-07-01 Deciphera Pharmaceuticals Llc GCN2 and PERK kinase inhibitors and methods of using them
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Also Published As

Publication number Publication date
PL2074122T3 (pl) 2011-10-31
US20120309775A1 (en) 2012-12-06
KR20090040389A (ko) 2009-04-23
AP2009004790A0 (en) 2009-04-30
TW200820972A (en) 2008-05-16
US8633204B2 (en) 2014-01-21
EA200970207A1 (ru) 2009-08-28
HRP20110621T1 (en) 2011-09-30
CN101573358A (zh) 2009-11-04
NO342357B1 (no) 2018-05-14
GT200700077A (es) 2009-08-03
MY146420A (en) 2012-08-15
PT2074122E (pt) 2011-08-24
CN101573358B (zh) 2012-05-30
RS20090104A (xx) 2010-06-30
JP2010503653A (ja) 2010-02-04
SI2074122T1 (sl) 2011-10-28
NI200900032A (es) 2010-05-14
KR101099926B1 (ko) 2011-12-28
GEP20115306B (xx) 2011-10-10
CA2663401A1 (en) 2008-03-20
US8273755B2 (en) 2012-09-25
HK1138589A1 (en) 2010-08-27
DK2074122T5 (da) 2014-03-17
RS51927B (en) 2012-02-29
US20100137279A1 (en) 2010-06-03
MA30709B1 (fr) 2009-09-01
AU2007297212B2 (en) 2011-04-14
IL197243A0 (en) 2009-12-24
CL2007002682A1 (es) 2008-04-04
MEP8009A (en) 2011-12-20
TN2009000085A1 (fr) 2010-08-19
BRPI0716749A2 (pt) 2014-02-18
NZ575167A (en) 2010-10-29
ES2366489T9 (es) 2013-12-27
ZA200901477B (en) 2010-07-28
EP2074122A1 (en) 2009-07-01
EA016388B1 (ru) 2012-04-30
IL197243A (en) 2013-07-31
CR10662A (es) 2009-04-17
DK2074122T3 (da) 2011-08-15
EP2074122B9 (en) 2013-09-11
WO2008032162A8 (en) 2009-03-26
CU20090040A7 (es) 2011-07-11
BRPI0716749B8 (pt) 2021-05-25
MX2009002927A (es) 2009-03-31
JP4718637B2 (ja) 2011-07-06
UY30588A1 (es) 2008-05-02
CY1111911T1 (el) 2015-11-04
EP2074122B1 (en) 2011-06-29
ATE514695T1 (de) 2011-07-15
TWI334353B (en) 2010-12-11
US7696213B2 (en) 2010-04-13
HRP20110621T2 (hr) 2013-12-06
PE20080670A1 (es) 2008-06-14
CU23783B7 (es) 2012-02-15
CA2663401C (en) 2011-07-12
US20080090801A1 (en) 2008-04-17
WO2008032162A1 (en) 2008-03-20
BRPI0716749B1 (pt) 2020-10-06
DOP2009000039A (es) 2015-12-15
AU2007297212B8 (en) 2011-04-28
HN2007000267A (es) 2011-02-25
NO20091141L (no) 2009-03-31
AR062785A1 (es) 2008-12-03
AU2007297212A1 (en) 2008-03-20
ES2366489T3 (es) 2011-10-20

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