PT88924B - Processo para a preparacao de derivados de ginkgolidos - Google Patents

Processo para a preparacao de derivados de ginkgolidos Download PDF

Info

Publication number
PT88924B
PT88924B PT88924A PT8892488A PT88924B PT 88924 B PT88924 B PT 88924B PT 88924 A PT88924 A PT 88924A PT 8892488 A PT8892488 A PT 8892488A PT 88924 B PT88924 B PT 88924B
Authority
PT
Portugal
Prior art keywords
ginkgolide
alkoxy
derivatives
preparation
ethoxy
Prior art date
Application number
PT88924A
Other languages
English (en)
Portuguese (pt)
Other versions
PT88924A (pt
Inventor
Pierre Braquet
Andre Esanu
Original Assignee
Scras
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scras filed Critical Scras
Publication of PT88924A publication Critical patent/PT88924A/pt
Publication of PT88924B publication Critical patent/PT88924B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
PT88924A 1987-11-04 1988-11-03 Processo para a preparacao de derivados de ginkgolidos PT88924B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878725871A GB8725871D0 (en) 1987-11-04 1987-11-04 Ginkgolide derivatives

Publications (2)

Publication Number Publication Date
PT88924A PT88924A (pt) 1988-12-01
PT88924B true PT88924B (pt) 1993-01-29

Family

ID=10626449

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88924A PT88924B (pt) 1987-11-04 1988-11-03 Processo para a preparacao de derivados de ginkgolidos

Country Status (28)

Country Link
JP (1) JPH0686455B2 (de)
KR (1) KR970005536B1 (de)
AT (1) AT397097B (de)
AU (1) AU616367B2 (de)
BE (1) BE1003455A3 (de)
CA (1) CA1303619C (de)
CH (1) CH675583A5 (de)
DE (1) DE3837550A1 (de)
DK (1) DK612788A (de)
ES (1) ES2009364A6 (de)
FI (1) FI90081C (de)
FR (2) FR2622448B1 (de)
GB (2) GB8725871D0 (de)
GR (1) GR1000264B (de)
HK (1) HK53992A (de)
IE (1) IE61541B1 (de)
IN (1) IN173404B (de)
IT (1) IT1227456B (de)
MA (1) MA21423A1 (de)
MY (1) MY103446A (de)
NL (1) NL8802635A (de)
NO (1) NO167739C (de)
NZ (1) NZ226738A (de)
PT (1) PT88924B (de)
SE (1) SE8803931L (de)
SG (1) SG48292G (de)
TN (1) TNSN88118A1 (de)
ZA (1) ZA888184B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5895785A (en) * 1987-10-20 1999-04-20 Ruth Korth Treatment and prevention of disorders mediated by LA-paf or endothelial cells
DE69132379T2 (de) * 1990-06-06 2001-03-01 Ruth-Maria Korth Behandlung von Erkrankungen mit Paf-Antagonisten und Verfahren zur Bestimmung deren Wirksamkeit
ES2181665T3 (es) * 1991-11-04 2003-03-01 Ruth-Maria Korth Tratamiento y prevencion de enfermedades mentales, acompañadas por unos elevados niveles de liso paf, con los antagonistas de paf.
FR2763592B1 (fr) * 1997-05-20 1999-07-16 Sod Conseils Rech Applic Nouveaux derives glycosyles des ginkgolides, leur application en tant que medicaments et compositions pharmaceutiques les contenant
FR2777280B1 (fr) * 1998-04-10 2001-04-20 Centre Nat Rech Scient Derives de ginkgolides, leur procede de preparation et compositions pharmaceutiques les contenant
US10875874B2 (en) 2015-12-18 2020-12-29 Chengdu Baiyu Ginkgolide Pharmaceuticals Co. Ltd. Ginkgolide B derivative and preparation method and use thereof
CN108383852B (zh) * 2017-12-25 2019-11-22 上海信谊百路达药业有限公司 一种从银杏叶中提取的银杏内酯化合物及其制备
CN108373474B (zh) * 2017-12-25 2020-06-09 上海信谊百路达药业有限公司 一种从银杏叶中提取的银杏内酯化合物及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8418424D0 (en) * 1984-07-19 1984-08-22 Scras Inhibition of platelets aggregation
DE3710921C2 (de) * 1986-10-21 1996-09-26 Korth Ruth Verwendung der Gingkolide BN 52020, BN 52021 und BN 52063 zur Behandlung von Arteriosklerose
DE3735525C2 (de) * 1987-10-20 1997-02-20 Korth Ruth Maria Verfahren zur Bestimmung der Wirksamkeit von paf-Acether-Rezeptor-Antagonisten

Also Published As

Publication number Publication date
IE61541B1 (en) 1994-11-16
SE8803931D0 (sv) 1988-10-31
ZA888184B (en) 1989-07-26
GB8725871D0 (en) 1987-12-09
GB2211841A (en) 1989-07-12
FI885046A0 (fi) 1988-11-02
IE883315L (en) 1989-05-04
DE3837550C2 (de) 1991-12-12
FR2622584A1 (fr) 1989-05-05
GR1000264B (el) 1992-05-12
BE1003455A3 (fr) 1992-03-31
DE3837550A1 (de) 1989-05-18
NO167739B (no) 1991-08-26
CA1303619C (en) 1992-06-16
SG48292G (en) 1992-06-12
MY103446A (en) 1993-06-30
NO884900L (no) 1989-05-05
FR2622584B1 (fr) 1992-01-10
NZ226738A (en) 1990-05-28
IN173404B (de) 1994-04-30
FR2622448B1 (fr) 1992-01-10
PT88924A (pt) 1988-12-01
ES2009364A6 (es) 1989-09-16
FI90081B (fi) 1993-09-15
GB2211841B (en) 1991-01-16
AU2464488A (en) 1989-05-25
DK612788D0 (da) 1988-11-03
KR970005536B1 (ko) 1997-04-17
DK612788A (da) 1989-05-05
TNSN88118A1 (fr) 1990-07-10
AT397097B (de) 1994-01-25
FR2622448A1 (fr) 1989-05-05
MA21423A1 (fr) 1989-07-01
FI885046A (fi) 1989-05-05
GB8824859D0 (en) 1988-11-30
NO167739C (no) 1991-12-04
CH675583A5 (de) 1990-10-15
NL8802635A (nl) 1989-06-01
FI90081C (fi) 1993-12-27
NO884900D0 (no) 1988-11-03
AU616367B2 (en) 1991-10-24
HK53992A (en) 1992-07-30
IT8822493A0 (it) 1988-11-04
JPH0686455B2 (ja) 1994-11-02
IT1227456B (it) 1991-04-11
SE8803931L (sv) 1989-05-05
KR890008156A (ko) 1989-07-10
ATA269688A (de) 1993-06-15
JPH01151583A (ja) 1989-06-14

Similar Documents

Publication Publication Date Title
EP0244832B1 (de) Ungesättigte Fettsäuren enthaltende Zubereitungen für die Synthese von Prostaglandinen und Hydroxyfettsäuren in biologischen Systemen
JPH0367045B2 (de)
PT85594B (pt) Processo para a preparacao de novos derivados de xantina
PT88924B (pt) Processo para a preparacao de derivados de ginkgolidos
EP0373663B1 (de) Castanospermin-ester zur Hemmung der Tumormetastasierung
JPS61246183A (ja) 置換１，８‐ナフチリジノン類、それらの製造方法およびそれらを含む医薬組成物
JPH03209322A (ja) ピリミドン誘導体及び類似化合物を含有するある種の皮膚疾患の局所投与治療用医薬組成物
EP0011447B1 (de) Die Blutplättchenaggregation inhibierende Derivate der 1-Benzyl-1,2,5,6-tetrahydropyridin-3-carbonsäure und ihre Salze, diese Verbindungen enthaltende pharmazeutische Zusammensetzungen und Verfahren zu ihrer Herstellung
JP2002504509A (ja) タンパク質ファルネシル転移酵素阻害剤
AP339A (en) Indenoindoles compounds.
US2849369A (en) Therapeutic compositions of cyanacetic acid hydrazide and acid addition salts thereof, and processes employing the same
EP0402033A1 (de) Carboxamidderivate
US4393081A (en) Methyl 3-acetamido-2-(5-methoxy-indol-3-yl) propanoate and hypotensive use thereof
US4145438A (en) Method for treatment of eczema or psoriasis
JPS6245525A (ja) 脂質低下剤
US4496577A (en) Imidazolidinone prostaglandins, compositions and use
US3073740A (en) Method of reducing cholesterol levels with tri- (dialkylaminoalkyl) phosphates
US4268518A (en) Method of treating cystitis
US4443458A (en) Aminocrotonyl 3,5-dinitropyridine useful as adjuncts to radiation therapy
DE3642648A1 (de) Verwendung von 6-allyl-2-amino-5,6,7,8-tetrahydro-4h-thiazolo-(5,4-d)azepin zur freisetzung von wachstumshormon
EP0153171A2 (de) 2-Hydroxyethyltrimethylammonium-Salz von 1-Ethyl-3-carboxy-4-oxo-6,7-methylendioxy-1,4-dihydrochinolin, Verfahren zu seiner Herstellung und dieses enthaltende pharmazeutische Zubereitung
PT87689B (pt) Processo para a preparacao de novos aminoacilatos de glicerol acetal
WO1998057645A1 (fr) Medicament contre l'oedeme hepatique
KR19990066201A (ko) 악티게닌 유도체 및 이를 주성분으로 함유하는 약학적 조성물
JPH0367050B2 (de)

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920706

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19980131