AU616367B2 - Ginkgolide derivatives - Google Patents

Ginkgolide derivatives Download PDF

Info

Publication number
AU616367B2
AU616367B2 AU24644/88A AU2464488A AU616367B2 AU 616367 B2 AU616367 B2 AU 616367B2 AU 24644/88 A AU24644/88 A AU 24644/88A AU 2464488 A AU2464488 A AU 2464488A AU 616367 B2 AU616367 B2 AU 616367B2
Authority
AU
Australia
Prior art keywords
ginkgolide
alkoxy
mixture
ginkgolides
diazoalkane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU24644/88A
Other languages
English (en)
Other versions
AU2464488A (en
Inventor
Pierre Braquet
Andre Esanu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Publication of AU2464488A publication Critical patent/AU2464488A/en
Application granted granted Critical
Publication of AU616367B2 publication Critical patent/AU616367B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
AU24644/88A 1987-11-04 1988-11-03 Ginkgolide derivatives Ceased AU616367B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8725871 1987-11-04
GB878725871A GB8725871D0 (en) 1987-11-04 1987-11-04 Ginkgolide derivatives

Publications (2)

Publication Number Publication Date
AU2464488A AU2464488A (en) 1989-05-25
AU616367B2 true AU616367B2 (en) 1991-10-24

Family

ID=10626449

Family Applications (1)

Application Number Title Priority Date Filing Date
AU24644/88A Ceased AU616367B2 (en) 1987-11-04 1988-11-03 Ginkgolide derivatives

Country Status (28)

Country Link
JP (1) JPH0686455B2 (de)
KR (1) KR970005536B1 (de)
AT (1) AT397097B (de)
AU (1) AU616367B2 (de)
BE (1) BE1003455A3 (de)
CA (1) CA1303619C (de)
CH (1) CH675583A5 (de)
DE (1) DE3837550A1 (de)
DK (1) DK612788A (de)
ES (1) ES2009364A6 (de)
FI (1) FI90081C (de)
FR (2) FR2622448B1 (de)
GB (2) GB8725871D0 (de)
GR (1) GR1000264B (de)
HK (1) HK53992A (de)
IE (1) IE61541B1 (de)
IN (1) IN173404B (de)
IT (1) IT1227456B (de)
MA (1) MA21423A1 (de)
MY (1) MY103446A (de)
NL (1) NL8802635A (de)
NO (1) NO167739C (de)
NZ (1) NZ226738A (de)
PT (1) PT88924B (de)
SE (1) SE8803931L (de)
SG (1) SG48292G (de)
TN (1) TNSN88118A1 (de)
ZA (1) ZA888184B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5895785A (en) * 1987-10-20 1999-04-20 Ruth Korth Treatment and prevention of disorders mediated by LA-paf or endothelial cells
DE69132379T2 (de) * 1990-06-06 2001-03-01 Ruth-Maria Korth Behandlung von Erkrankungen mit Paf-Antagonisten und Verfahren zur Bestimmung deren Wirksamkeit
ES2181665T3 (es) * 1991-11-04 2003-03-01 Ruth-Maria Korth Tratamiento y prevencion de enfermedades mentales, acompañadas por unos elevados niveles de liso paf, con los antagonistas de paf.
FR2763592B1 (fr) * 1997-05-20 1999-07-16 Sod Conseils Rech Applic Nouveaux derives glycosyles des ginkgolides, leur application en tant que medicaments et compositions pharmaceutiques les contenant
FR2777280B1 (fr) * 1998-04-10 2001-04-20 Centre Nat Rech Scient Derives de ginkgolides, leur procede de preparation et compositions pharmaceutiques les contenant
US10875874B2 (en) 2015-12-18 2020-12-29 Chengdu Baiyu Ginkgolide Pharmaceuticals Co. Ltd. Ginkgolide B derivative and preparation method and use thereof
CN108383852B (zh) * 2017-12-25 2019-11-22 上海信谊百路达药业有限公司 一种从银杏叶中提取的银杏内酯化合物及其制备
CN108373474B (zh) * 2017-12-25 2020-06-09 上海信谊百路达药业有限公司 一种从银杏叶中提取的银杏内酯化合物及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8418424D0 (en) * 1984-07-19 1984-08-22 Scras Inhibition of platelets aggregation
DE3710921C2 (de) * 1986-10-21 1996-09-26 Korth Ruth Verwendung der Gingkolide BN 52020, BN 52021 und BN 52063 zur Behandlung von Arteriosklerose
DE3735525C2 (de) * 1987-10-20 1997-02-20 Korth Ruth Maria Verfahren zur Bestimmung der Wirksamkeit von paf-Acether-Rezeptor-Antagonisten

Also Published As

Publication number Publication date
IE61541B1 (en) 1994-11-16
SE8803931D0 (sv) 1988-10-31
ZA888184B (en) 1989-07-26
GB8725871D0 (en) 1987-12-09
GB2211841A (en) 1989-07-12
FI885046A0 (fi) 1988-11-02
IE883315L (en) 1989-05-04
DE3837550C2 (de) 1991-12-12
FR2622584A1 (fr) 1989-05-05
GR1000264B (el) 1992-05-12
BE1003455A3 (fr) 1992-03-31
DE3837550A1 (de) 1989-05-18
NO167739B (no) 1991-08-26
CA1303619C (en) 1992-06-16
SG48292G (en) 1992-06-12
MY103446A (en) 1993-06-30
NO884900L (no) 1989-05-05
FR2622584B1 (fr) 1992-01-10
NZ226738A (en) 1990-05-28
IN173404B (de) 1994-04-30
FR2622448B1 (fr) 1992-01-10
PT88924A (pt) 1988-12-01
ES2009364A6 (es) 1989-09-16
FI90081B (fi) 1993-09-15
GB2211841B (en) 1991-01-16
AU2464488A (en) 1989-05-25
DK612788D0 (da) 1988-11-03
KR970005536B1 (ko) 1997-04-17
DK612788A (da) 1989-05-05
PT88924B (pt) 1993-01-29
TNSN88118A1 (fr) 1990-07-10
AT397097B (de) 1994-01-25
FR2622448A1 (fr) 1989-05-05
MA21423A1 (fr) 1989-07-01
FI885046A (fi) 1989-05-05
GB8824859D0 (en) 1988-11-30
NO167739C (no) 1991-12-04
CH675583A5 (de) 1990-10-15
NL8802635A (nl) 1989-06-01
FI90081C (fi) 1993-12-27
NO884900D0 (no) 1988-11-03
HK53992A (en) 1992-07-30
IT8822493A0 (it) 1988-11-04
JPH0686455B2 (ja) 1994-11-02
IT1227456B (it) 1991-04-11
SE8803931L (sv) 1989-05-05
KR890008156A (ko) 1989-07-10
ATA269688A (de) 1993-06-15
JPH01151583A (ja) 1989-06-14

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