TNSN88118A1 - Procede de preparation de derives des ginkgolides - Google Patents

Procede de preparation de derives des ginkgolides

Info

Publication number
TNSN88118A1
TNSN88118A1 TNTNSN88118A TNSN88118A TNSN88118A1 TN SN88118 A1 TNSN88118 A1 TN SN88118A1 TN TNSN88118 A TNTNSN88118 A TN TNSN88118A TN SN88118 A TNSN88118 A TN SN88118A TN SN88118 A1 TNSN88118 A1 TN SN88118A1
Authority
TN
Tunisia
Prior art keywords
derivatives
preparation
ginkgolid
ethyl ethyl
alcoxy
Prior art date
Application number
TNTNSN88118A
Other languages
English (en)
Inventor
Braquet Pierre
Esanu Andre
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of TNSN88118A1 publication Critical patent/TNSN88118A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)

Abstract

LA PRESENTE INVENTION CONCERNE UN PROCEDE DE PREPARATION DE DERIVES ALCOXY-1 OU ALCOXY-10 DES GINKGOLIDES CONSISTANT A FAIRE REAGIR UNE SOLUTION DE DIOXANE D'UN GINKGOLIDE CHOISI AVEC UNE SOLUTION DANS L'ETHER ETHYLIQUE DE DIAZOALCANE EN EXCES, A TEMPERATURE AMBIANTE, PENDANT UNE A DIX HEURES.
TNTNSN88118A 1987-11-04 1988-11-03 Procede de preparation de derives des ginkgolides TNSN88118A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878725871A GB8725871D0 (en) 1987-11-04 1987-11-04 Ginkgolide derivatives

Publications (1)

Publication Number Publication Date
TNSN88118A1 true TNSN88118A1 (fr) 1990-07-10

Family

ID=10626449

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN88118A TNSN88118A1 (fr) 1987-11-04 1988-11-03 Procede de preparation de derives des ginkgolides

Country Status (28)

Country Link
JP (1) JPH0686455B2 (fr)
KR (1) KR970005536B1 (fr)
AT (1) AT397097B (fr)
AU (1) AU616367B2 (fr)
BE (1) BE1003455A3 (fr)
CA (1) CA1303619C (fr)
CH (1) CH675583A5 (fr)
DE (1) DE3837550A1 (fr)
DK (1) DK612788A (fr)
ES (1) ES2009364A6 (fr)
FI (1) FI90081C (fr)
FR (2) FR2622448B1 (fr)
GB (2) GB8725871D0 (fr)
GR (1) GR1000264B (fr)
HK (1) HK53992A (fr)
IE (1) IE61541B1 (fr)
IN (1) IN173404B (fr)
IT (1) IT1227456B (fr)
MA (1) MA21423A1 (fr)
MY (1) MY103446A (fr)
NL (1) NL8802635A (fr)
NO (1) NO167739C (fr)
NZ (1) NZ226738A (fr)
PT (1) PT88924B (fr)
SE (1) SE8803931L (fr)
SG (1) SG48292G (fr)
TN (1) TNSN88118A1 (fr)
ZA (1) ZA888184B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5895785A (en) * 1987-10-20 1999-04-20 Ruth Korth Treatment and prevention of disorders mediated by LA-paf or endothelial cells
EP0540767B9 (fr) * 1991-11-04 2004-12-22 Korth, Ruth-Maria, Dr. med Traitement et prévention de maladies mentales, induites par des taux de lyso-PAF élevés, avec des antagonistes du PAF
DE69132379T2 (de) * 1990-06-06 2001-03-01 Ruth-Maria Korth Behandlung von Erkrankungen mit Paf-Antagonisten und Verfahren zur Bestimmung deren Wirksamkeit
FR2763592B1 (fr) * 1997-05-20 1999-07-16 Sod Conseils Rech Applic Nouveaux derives glycosyles des ginkgolides, leur application en tant que medicaments et compositions pharmaceutiques les contenant
FR2777280B1 (fr) * 1998-04-10 2001-04-20 Centre Nat Rech Scient Derives de ginkgolides, leur procede de preparation et compositions pharmaceutiques les contenant
US10875874B2 (en) 2015-12-18 2020-12-29 Chengdu Baiyu Ginkgolide Pharmaceuticals Co. Ltd. Ginkgolide B derivative and preparation method and use thereof
CN108373474B (zh) * 2017-12-25 2020-06-09 上海信谊百路达药业有限公司 一种从银杏叶中提取的银杏内酯化合物及其制备方法
CN108383852B (zh) * 2017-12-25 2019-11-22 上海信谊百路达药业有限公司 一种从银杏叶中提取的银杏内酯化合物及其制备

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8418424D0 (en) * 1984-07-19 1984-08-22 Scras Inhibition of platelets aggregation
DE3710921C2 (de) * 1986-10-21 1996-09-26 Korth Ruth Verwendung der Gingkolide BN 52020, BN 52021 und BN 52063 zur Behandlung von Arteriosklerose
DE3735525C2 (de) * 1987-10-20 1997-02-20 Korth Ruth Maria Verfahren zur Bestimmung der Wirksamkeit von paf-Acether-Rezeptor-Antagonisten

Also Published As

Publication number Publication date
JPH0686455B2 (ja) 1994-11-02
CH675583A5 (fr) 1990-10-15
NO167739B (no) 1991-08-26
BE1003455A3 (fr) 1992-03-31
GB8725871D0 (en) 1987-12-09
DK612788A (da) 1989-05-05
PT88924B (pt) 1993-01-29
FI90081B (fi) 1993-09-15
FR2622584A1 (fr) 1989-05-05
IT1227456B (it) 1991-04-11
AU2464488A (en) 1989-05-25
FR2622584B1 (fr) 1992-01-10
NO167739C (no) 1991-12-04
CA1303619C (fr) 1992-06-16
KR890008156A (ko) 1989-07-10
GB2211841B (en) 1991-01-16
DE3837550C2 (fr) 1991-12-12
ATA269688A (de) 1993-06-15
NL8802635A (nl) 1989-06-01
MA21423A1 (fr) 1989-07-01
SG48292G (en) 1992-06-12
GB8824859D0 (en) 1988-11-30
GR1000264B (el) 1992-05-12
FR2622448B1 (fr) 1992-01-10
FI90081C (fi) 1993-12-27
ZA888184B (en) 1989-07-26
NO884900L (no) 1989-05-05
PT88924A (pt) 1988-12-01
GB2211841A (en) 1989-07-12
DE3837550A1 (de) 1989-05-18
FI885046A (fi) 1989-05-05
JPH01151583A (ja) 1989-06-14
DK612788D0 (da) 1988-11-03
NO884900D0 (no) 1988-11-03
FI885046A0 (fi) 1988-11-02
SE8803931D0 (sv) 1988-10-31
MY103446A (en) 1993-06-30
IN173404B (fr) 1994-04-30
HK53992A (en) 1992-07-30
IT8822493A0 (it) 1988-11-04
FR2622448A1 (fr) 1989-05-05
AU616367B2 (en) 1991-10-24
IE883315L (en) 1989-05-04
KR970005536B1 (ko) 1997-04-17
ES2009364A6 (es) 1989-09-16
NZ226738A (en) 1990-05-28
SE8803931L (sv) 1989-05-05
AT397097B (de) 1994-01-25
IE61541B1 (en) 1994-11-16

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