ES2009364A6 - Procedimiento de preparacion de derivados de ginkgolidas. - Google Patents
Procedimiento de preparacion de derivados de ginkgolidas.Info
- Publication number
- ES2009364A6 ES2009364A6 ES8803334A ES8803334A ES2009364A6 ES 2009364 A6 ES2009364 A6 ES 2009364A6 ES 8803334 A ES8803334 A ES 8803334A ES 8803334 A ES8803334 A ES 8803334A ES 2009364 A6 ES2009364 A6 ES 2009364A6
- Authority
- ES
- Spain
- Prior art keywords
- derivatives
- ginkgolide
- alkoxy
- mixture
- ginkgolide derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Steroid Compounds (AREA)
Abstract
ESTE INVENTO SE REFIERE A UN PROCEDIMIENTO PARA PREPARAR DERIVADOS DE GINKGOLIDAS SUSTITUIDAS POR 1-ALCOXI O 10-ALCOXI, QUE CONSISTE EN HACER REACCIONAR UNA SOLUCION EN DIOXANO DE LA GINKGOLIDA SELECCIONADA CON UNA SOLUCION EN ETER DIETILICO DE DIAZOALCANO EN EXCESO, A LA TEMPERATURA AMBIENTE DURANTE 1 A 10 HORAS. LOS DERIVADOS PREPARADOS TIENEN INTERES EN EL TRATAMIENTO DE ENFERMEDADES INDUCIDAS POR PAF-ACETHER.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB878725871A GB8725871D0 (en) | 1987-11-04 | 1987-11-04 | Ginkgolide derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2009364A6 true ES2009364A6 (es) | 1989-09-16 |
Family
ID=10626449
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8803334A Expired ES2009364A6 (es) | 1987-11-04 | 1988-11-02 | Procedimiento de preparacion de derivados de ginkgolidas. |
Country Status (28)
Country | Link |
---|---|
JP (1) | JPH0686455B2 (es) |
KR (1) | KR970005536B1 (es) |
AT (1) | AT397097B (es) |
AU (1) | AU616367B2 (es) |
BE (1) | BE1003455A3 (es) |
CA (1) | CA1303619C (es) |
CH (1) | CH675583A5 (es) |
DE (1) | DE3837550A1 (es) |
DK (1) | DK612788A (es) |
ES (1) | ES2009364A6 (es) |
FI (1) | FI90081C (es) |
FR (2) | FR2622584B1 (es) |
GB (2) | GB8725871D0 (es) |
GR (1) | GR1000264B (es) |
HK (1) | HK53992A (es) |
IE (1) | IE61541B1 (es) |
IN (1) | IN173404B (es) |
IT (1) | IT1227456B (es) |
MA (1) | MA21423A1 (es) |
MY (1) | MY103446A (es) |
NL (1) | NL8802635A (es) |
NO (1) | NO167739C (es) |
NZ (1) | NZ226738A (es) |
PT (1) | PT88924B (es) |
SE (1) | SE8803931L (es) |
SG (1) | SG48292G (es) |
TN (1) | TNSN88118A1 (es) |
ZA (1) | ZA888184B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5895785A (en) * | 1987-10-20 | 1999-04-20 | Ruth Korth | Treatment and prevention of disorders mediated by LA-paf or endothelial cells |
EP0540767B9 (en) * | 1991-11-04 | 2004-12-22 | Korth, Ruth-Maria, Dr. med | Treatment and prevention of mental diseases mediated by elevated lyso paf levels with paf antagonists |
EP0459432B1 (en) * | 1990-06-01 | 2000-08-23 | Korth, Ruth, Dr. med. | Treatment of diseases with paf-antagonists and procedure for determining their efficacy |
FR2763592B1 (fr) * | 1997-05-20 | 1999-07-16 | Sod Conseils Rech Applic | Nouveaux derives glycosyles des ginkgolides, leur application en tant que medicaments et compositions pharmaceutiques les contenant |
FR2777280B1 (fr) * | 1998-04-10 | 2001-04-20 | Centre Nat Rech Scient | Derives de ginkgolides, leur procede de preparation et compositions pharmaceutiques les contenant |
US10875874B2 (en) | 2015-12-18 | 2020-12-29 | Chengdu Baiyu Ginkgolide Pharmaceuticals Co. Ltd. | Ginkgolide B derivative and preparation method and use thereof |
CN108373474B (zh) * | 2017-12-25 | 2020-06-09 | 上海信谊百路达药业有限公司 | 一种从银杏叶中提取的银杏内酯化合物及其制备方法 |
CN108383852B (zh) * | 2017-12-25 | 2019-11-22 | 上海信谊百路达药业有限公司 | 一种从银杏叶中提取的银杏内酯化合物及其制备 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8418424D0 (en) * | 1984-07-19 | 1984-08-22 | Scras | Inhibition of platelets aggregation |
DE3710921C2 (de) * | 1986-10-21 | 1996-09-26 | Korth Ruth | Verwendung der Gingkolide BN 52020, BN 52021 und BN 52063 zur Behandlung von Arteriosklerose |
DE3735525C2 (de) * | 1987-10-20 | 1997-02-20 | Korth Ruth Maria | Verfahren zur Bestimmung der Wirksamkeit von paf-Acether-Rezeptor-Antagonisten |
-
1987
- 1987-11-04 GB GB878725871A patent/GB8725871D0/en active Pending
-
1988
- 1988-10-24 GB GB8824859A patent/GB2211841B/en not_active Expired - Fee Related
- 1988-10-26 IN IN928DE1988 patent/IN173404B/en unknown
- 1988-10-26 GR GR880100726A patent/GR1000264B/el unknown
- 1988-10-26 NL NL8802635A patent/NL8802635A/nl not_active Application Discontinuation
- 1988-10-27 NZ NZ226738A patent/NZ226738A/xx unknown
- 1988-10-28 BE BE8801244A patent/BE1003455A3/fr not_active IP Right Cessation
- 1988-10-28 MY MYPI88001236A patent/MY103446A/en unknown
- 1988-10-31 SE SE8803931A patent/SE8803931L/xx not_active Application Discontinuation
- 1988-11-01 MA MA21665A patent/MA21423A1/fr unknown
- 1988-11-01 ZA ZA888184A patent/ZA888184B/xx unknown
- 1988-11-02 AT AT0269688A patent/AT397097B/de not_active IP Right Cessation
- 1988-11-02 FI FI885046A patent/FI90081C/fi not_active IP Right Cessation
- 1988-11-02 ES ES8803334A patent/ES2009364A6/es not_active Expired
- 1988-11-03 IE IE331588A patent/IE61541B1/en not_active IP Right Cessation
- 1988-11-03 PT PT88924A patent/PT88924B/pt not_active IP Right Cessation
- 1988-11-03 CH CH4081/88A patent/CH675583A5/fr not_active IP Right Cessation
- 1988-11-03 CA CA000582165A patent/CA1303619C/en not_active Expired - Fee Related
- 1988-11-03 AU AU24644/88A patent/AU616367B2/en not_active Ceased
- 1988-11-03 TN TNTNSN88118A patent/TNSN88118A1/fr unknown
- 1988-11-03 DK DK612788A patent/DK612788A/da not_active Application Discontinuation
- 1988-11-03 NO NO884900A patent/NO167739C/no unknown
- 1988-11-03 KR KR1019880014439A patent/KR970005536B1/ko active IP Right Grant
- 1988-11-04 FR FR888814392A patent/FR2622584B1/fr not_active Expired - Fee Related
- 1988-11-04 DE DE3837550A patent/DE3837550A1/de active Granted
- 1988-11-04 JP JP63277522A patent/JPH0686455B2/ja not_active Expired - Lifetime
- 1988-11-04 FR FR888814393A patent/FR2622448B1/fr not_active Expired - Fee Related
- 1988-11-04 IT IT8822493A patent/IT1227456B/it active
-
1992
- 1992-04-29 SG SG48292A patent/SG48292G/en unknown
- 1992-07-23 HK HK539/92A patent/HK53992A/xx not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL87972A (en) | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives, their preparation and pharmaceutical compositions containing them | |
ZA877530B (en) | Imidazopyridine derivatives and pharmaceutical compositions containing the same as well as processes for production thereof | |
MX9202851A (es) | Derivados de fosfato de los glucosidos de 4-desmetilepipodofilotoxina y composicion farmaceutica que los contiene. | |
IE781716L (en) | Trihydroxypiperidine compounds | |
IL88765A (en) | N-hydroxycycloalkyl or n-hydroxycycloalkenyl- substituted adenosine derivatives, methods for their preparation and pharmaceutical compositions, including antilipolytic compositions, containing the same | |
IL83659A0 (en) | Xanthine derivatives,their production and pharmaceutical compositions containing them | |
AU506736B2 (en) | Separation of materi-J. s using fluorescence | |
IL55338A0 (en) | Novel pyrido (1,2-a)pyrimidine derivatives, their preparation and pharmaceutical compositions containing them | |
AU2024388A (en) | Alkylaminoalkoxyphenyl derivatives, process of preparation and compositions containing the same | |
ES2009364A6 (es) | Procedimiento de preparacion de derivados de ginkgolidas. | |
IL79727A (en) | 9-(2-fluoro-3-hydroxy-4-(hydroxymethyl)cyclopentyl)guanine,its preparation and pharmaceutical compositions containing it | |
ZA814139B (en) | Novel adenine nucleoside derivatives their preparation and pharmaceutical compositions containing them | |
IL88138A0 (en) | Purine derivatives,their preparation and pharmaceutical compositions containing them | |
IL54814A (en) | 5,11-dihydro-11(piperazin-1-yl-alkanoyl)-6h-pyrido(2,3-b) (1,4)benzoidiazepin-6-one derivatives,their preparation and pharmaceutical compositions containing them | |
AU1373688A (en) | Imidazopyridine derivatives and compositions containing them | |
IL85189A (en) | Beta-alkyl substituted melatonins,their preparation and pharmaceutical compositions containing them | |
GB2202145B (en) | Compositions of nedocromil for dermatological use. | |
ZA85143B (en) | Novel delta4-and delta5-androstene derivatives,processes for their preparation and pharmaceutical compositions containing these derivates | |
IL87494A0 (en) | Pharmaceutical compositions containing benzylpyrimidine derivatives | |
IL55134A0 (en) | Novel benzopyrane derivatives,their preparation and pharmaceutical compositions containing them | |
ES8203334A1 (es) | Procedimiento para la obtencion de dehidropeptidos | |
IL85624A0 (en) | Imidazodiazepine derivatives,their manufacture and pharmaceutical compositions containing them | |
IL59177A (en) | Spirofuro-(and pyrano)-quinolylhydantoins and pharmaceutical compositions containing them | |
EP0335770A3 (en) | Novel fluorophosphonate nucleotide derivatives | |
IL54328A (en) | Substituted pyrido(2,1-b)quinazoline-11-one derivatives,their manufacture and pharmaceutical compositions containing them |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
SA6 | Expiration date (snapshot 920101) |
Free format text: 2008-11-02 |
|
FD1A | Patent lapsed |
Effective date: 20010503 |