GR1000264B - Μεθοδος παρασκευης παραγωγων ενωσεων ginkgo. - Google Patents

Μεθοδος παρασκευης παραγωγων ενωσεων ginkgo.

Info

Publication number
GR1000264B
GR1000264B GR880100726A GR880100726A GR1000264B GR 1000264 B GR1000264 B GR 1000264B GR 880100726 A GR880100726 A GR 880100726A GR 880100726 A GR880100726 A GR 880100726A GR 1000264 B GR1000264 B GR 1000264B
Authority
GR
Greece
Prior art keywords
preparation
ginkgo
compounds derivatives
solution
alcohol
Prior art date
Application number
GR880100726A
Other languages
English (en)
Inventor
Pierre Braquet
Andre Esanu
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of GR1000264B publication Critical patent/GR1000264B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)

Abstract

Η παρούσα εφεύρεσις αφορά μέθοδον παρασκευής 1-αλκοξυ ή 10- αλκοξυ υποκατεστημένων παραγώγων γκιγκολιδίων, συνισταμένην εις αντίδρασιν διοξανικού διαλύματος του επιλεγέντος γκιγκολιδίου μετά διαιθυλ-αιθερικού διαλύματος του διαζωαλκανίου εν περισσεία, εις θερμοκρασίαν δωματίου, επί 1 έως 10 ώρας. ω
GR880100726A 1987-11-04 1988-10-26 Μεθοδος παρασκευης παραγωγων ενωσεων ginkgo. GR1000264B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878725871A GB8725871D0 (en) 1987-11-04 1987-11-04 Ginkgolide derivatives

Publications (1)

Publication Number Publication Date
GR1000264B true GR1000264B (el) 1992-05-12

Family

ID=10626449

Family Applications (1)

Application Number Title Priority Date Filing Date
GR880100726A GR1000264B (el) 1987-11-04 1988-10-26 Μεθοδος παρασκευης παραγωγων ενωσεων ginkgo.

Country Status (28)

Country Link
JP (1) JPH0686455B2 (el)
KR (1) KR970005536B1 (el)
AT (1) AT397097B (el)
AU (1) AU616367B2 (el)
BE (1) BE1003455A3 (el)
CA (1) CA1303619C (el)
CH (1) CH675583A5 (el)
DE (1) DE3837550A1 (el)
DK (1) DK612788A (el)
ES (1) ES2009364A6 (el)
FI (1) FI90081C (el)
FR (2) FR2622584B1 (el)
GB (2) GB8725871D0 (el)
GR (1) GR1000264B (el)
HK (1) HK53992A (el)
IE (1) IE61541B1 (el)
IN (1) IN173404B (el)
IT (1) IT1227456B (el)
MA (1) MA21423A1 (el)
MY (1) MY103446A (el)
NL (1) NL8802635A (el)
NO (1) NO167739C (el)
NZ (1) NZ226738A (el)
PT (1) PT88924B (el)
SE (1) SE8803931L (el)
SG (1) SG48292G (el)
TN (1) TNSN88118A1 (el)
ZA (1) ZA888184B (el)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5895785A (en) * 1987-10-20 1999-04-20 Ruth Korth Treatment and prevention of disorders mediated by LA-paf or endothelial cells
EP0540767B9 (en) * 1991-11-04 2004-12-22 Korth, Ruth-Maria, Dr. med Treatment and prevention of mental diseases mediated by elevated lyso paf levels with paf antagonists
EP0459432B1 (en) * 1990-06-01 2000-08-23 Korth, Ruth, Dr. med. Treatment of diseases with paf-antagonists and procedure for determining their efficacy
FR2763592B1 (fr) * 1997-05-20 1999-07-16 Sod Conseils Rech Applic Nouveaux derives glycosyles des ginkgolides, leur application en tant que medicaments et compositions pharmaceutiques les contenant
FR2777280B1 (fr) * 1998-04-10 2001-04-20 Centre Nat Rech Scient Derives de ginkgolides, leur procede de preparation et compositions pharmaceutiques les contenant
US10875874B2 (en) 2015-12-18 2020-12-29 Chengdu Baiyu Ginkgolide Pharmaceuticals Co. Ltd. Ginkgolide B derivative and preparation method and use thereof
CN108373474B (zh) * 2017-12-25 2020-06-09 上海信谊百路达药业有限公司 一种从银杏叶中提取的银杏内酯化合物及其制备方法
CN108383852B (zh) * 2017-12-25 2019-11-22 上海信谊百路达药业有限公司 一种从银杏叶中提取的银杏内酯化合物及其制备

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2162062A (en) * 1984-07-19 1986-01-29 Scras Medicaments containing ginkgolides
DE3710921A1 (de) * 1986-10-21 1988-07-14 Korth Ruth Verwendung von paf-acether-bindungsstellen inhibierenden substanzen
EP0312913B1 (de) * 1987-10-20 1992-01-29 Korth, Ruth-Maria, Dr. med Verwendung von paf-Acether-Antagonisten zur Herstellung eines Arzneimittels und Verfahren zu deren Wirksamkeitsbestimmung

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2162062A (en) * 1984-07-19 1986-01-29 Scras Medicaments containing ginkgolides
DE3710921A1 (de) * 1986-10-21 1988-07-14 Korth Ruth Verwendung von paf-acether-bindungsstellen inhibierenden substanzen
EP0312913B1 (de) * 1987-10-20 1992-01-29 Korth, Ruth-Maria, Dr. med Verwendung von paf-Acether-Antagonisten zur Herstellung eines Arzneimittels und Verfahren zu deren Wirksamkeitsbestimmung

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 104, 1986, page 29, abstract no. 161678h, Columbus, Ohio, US; C. TOUVAY et al.: "Inhibition of antigen-induced lung anaphylaxis in the guinea pig by BN 52021 a new specific paf-acether receptor antagonist isolated from Ginkgo biloba", & AGENTS ACTIONS 1985, 17(3-4),371-2 *
CLAIMS SEARCHED: ALL *

Also Published As

Publication number Publication date
HK53992A (en) 1992-07-30
JPH01151583A (ja) 1989-06-14
DK612788D0 (da) 1988-11-03
SE8803931D0 (sv) 1988-10-31
NO884900L (no) 1989-05-05
KR890008156A (ko) 1989-07-10
FR2622584A1 (fr) 1989-05-05
BE1003455A3 (fr) 1992-03-31
AU2464488A (en) 1989-05-25
ATA269688A (de) 1993-06-15
NO167739C (no) 1991-12-04
GB2211841A (en) 1989-07-12
GB8725871D0 (en) 1987-12-09
ES2009364A6 (es) 1989-09-16
SE8803931L (sv) 1989-05-05
DE3837550A1 (de) 1989-05-18
MA21423A1 (fr) 1989-07-01
NL8802635A (nl) 1989-06-01
FI885046A (fi) 1989-05-05
FI90081B (fi) 1993-09-15
ZA888184B (en) 1989-07-26
FR2622584B1 (fr) 1992-01-10
CH675583A5 (el) 1990-10-15
TNSN88118A1 (fr) 1990-07-10
NO167739B (no) 1991-08-26
GB2211841B (en) 1991-01-16
FI90081C (fi) 1993-12-27
NO884900D0 (no) 1988-11-03
IE61541B1 (en) 1994-11-16
AU616367B2 (en) 1991-10-24
AT397097B (de) 1994-01-25
PT88924A (pt) 1988-12-01
GB8824859D0 (en) 1988-11-30
SG48292G (en) 1992-06-12
IN173404B (el) 1994-04-30
DK612788A (da) 1989-05-05
DE3837550C2 (el) 1991-12-12
IT1227456B (it) 1991-04-11
IE883315L (en) 1989-05-04
IT8822493A0 (it) 1988-11-04
CA1303619C (en) 1992-06-16
NZ226738A (en) 1990-05-28
KR970005536B1 (ko) 1997-04-17
FI885046A0 (fi) 1988-11-02
PT88924B (pt) 1993-01-29
FR2622448A1 (fr) 1989-05-05
MY103446A (en) 1993-06-30
JPH0686455B2 (ja) 1994-11-02
FR2622448B1 (fr) 1992-01-10

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GR1000264B (el) Μεθοδος παρασκευης παραγωγων ενωσεων ginkgo.
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