ATE221779T1 - Behandlung und vorbeugung von erhöhten lyso-paf- spiegel mediierten mentalen erkrankungen mit paf- antagonisten - Google Patents
Behandlung und vorbeugung von erhöhten lyso-paf- spiegel mediierten mentalen erkrankungen mit paf- antagonistenInfo
- Publication number
- ATE221779T1 ATE221779T1 AT91118745T AT91118745T ATE221779T1 AT E221779 T1 ATE221779 T1 AT E221779T1 AT 91118745 T AT91118745 T AT 91118745T AT 91118745 T AT91118745 T AT 91118745T AT E221779 T1 ATE221779 T1 AT E221779T1
- Authority
- AT
- Austria
- Prior art keywords
- paf
- lyso
- treatment
- antagonists
- ginkgolide
- Prior art date
Links
- 239000005557 antagonist Substances 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 230000003340 mental effect Effects 0.000 title abstract 3
- 230000002265 prevention Effects 0.000 title 1
- 229930184727 ginkgolide Natural products 0.000 abstract 3
- 208000027866 inflammatory disease Diseases 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 208000020016 psychiatric disease Diseases 0.000 abstract 2
- 239000003848 thrombocyte activating factor antagonist Substances 0.000 abstract 2
- 108700023400 Platelet-activating factor receptors Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000000440 neutrophil Anatomy 0.000 abstract 1
- 102000030769 platelet activating factor receptor Human genes 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Nutrition Science (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines Containing Plant Substances (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP91118745A EP0540767B9 (de) | 1991-11-04 | 1991-11-04 | Behandlung und Vorbeugung von erhöhten Lyso-PAF-Spiegel mediierten mentalen Erkrankungen mit PAF-Antagonisten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE221779T1 true ATE221779T1 (de) | 2002-08-15 |
Family
ID=8207297
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91118745T ATE221779T1 (de) | 1991-11-04 | 1991-11-04 | Behandlung und vorbeugung von erhöhten lyso-paf- spiegel mediierten mentalen erkrankungen mit paf- antagonisten |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US5346894A (de) |
| EP (1) | EP0540767B9 (de) |
| JP (1) | JPH06305981A (de) |
| AT (1) | ATE221779T1 (de) |
| DE (2) | DE69133083C5 (de) |
| ES (1) | ES2181665T3 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5895785A (en) * | 1987-10-20 | 1999-04-20 | Ruth Korth | Treatment and prevention of disorders mediated by LA-paf or endothelial cells |
| US5530023A (en) * | 1987-10-20 | 1996-06-25 | Korth; Ruth | Production of binding sites for PAF, PAF analogues and PAF antagonists in endothelial cells |
| US6274621B1 (en) | 1995-11-09 | 2001-08-14 | Societe De Conseils De Recherches Et D'applications Scientifiques, Sas | Ginkgolides for inhibition of membrane expression of benzodiazepine receptors |
| US5854279A (en) * | 1996-06-04 | 1998-12-29 | Eisai Co., Ltd | Therapeutic agent for dermatosis |
| US7078434B1 (en) * | 1999-08-12 | 2006-07-18 | Societe De Conseils De Recherches Et D'applications Scientifiques Sas | Use of Ginkgo extract |
| JP4733801B2 (ja) * | 1999-08-23 | 2011-07-27 | 丸善製薬株式会社 | エストロゲン様作用剤および皮膚化粧料 |
| US6583152B2 (en) * | 2001-04-30 | 2003-06-24 | Dexgen Pharmaceuticals, Inc. | Composition for reducing the risk or progression of cardiovascular diseases |
| US20050032713A1 (en) * | 2002-03-27 | 2005-02-10 | Wurtman Richard J. | Platelet-activating factor antagonists as analgesic, anti-inflammatory, uterine contraction inhibiting, and anti-tumor agents |
| US11039997B2 (en) | 2005-12-27 | 2021-06-22 | Ruth-Maria Korth | Cosmetic, dermatic, protective compositions comprising phospholipids, lecithins with peptides and at least one acetylating compound |
| DE102005062417A1 (de) * | 2005-12-27 | 2007-08-23 | Korth, Ruth-Maria, Dr.med. | Kompositionen mit spezifischen und unspezifischen Lipidantagonisten |
| RU2342131C2 (ru) * | 2007-01-29 | 2008-12-27 | Алена Борисовна Конькова-Рейдман | Применение цитофлавина для лечения клещевых нейроинфекций |
| JP5982676B2 (ja) * | 2011-02-28 | 2016-08-31 | 学校法人 いわき明星大学 | 抗paf活性を有するビオチニル化ペプチド化合物 |
| DE202011108417U1 (de) * | 2011-11-29 | 2012-03-01 | Ruth-Maria Korth | Örtliche und dietätische Kompositionen ohne Etherlipide, Etherphospholipide, Alkylradikale, die geeignet sind für sensible Personen |
| CN108096241B (zh) * | 2017-11-24 | 2020-06-16 | 江苏康缘药业股份有限公司 | 银杏内酯组合物的医药用途 |
| ES2958082T3 (es) | 2019-01-15 | 2024-02-01 | Dr Willmar Schwabe Gmbh & Co Kg | Procedimiento para la producción de comprimidos de fácil toma con extracto seco de hojas de Ginkgo biloba |
| DE202019003092U1 (de) | 2019-07-24 | 2020-01-17 | Ruth-Maria Korth | Test zur Bestimmung von Proteophospholipiden und FIDA-Formeln zur Bestimmung von Schutzfaktoren , die mit Substraten auszugleichen sind |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES547449A0 (es) * | 1971-06-18 | 1986-11-16 | Yoshitomi Pharmaceutical | Un metodo de preparacion de compuesto de triazolotienodiaze-pina |
| DE3338995A1 (de) * | 1983-10-27 | 1985-05-09 | Dr. Willmar Schwabe GmbH & Co, 7500 Karlsruhe | Bilobalid enthaltende arzneimittel |
| DE2732921A1 (de) * | 1977-07-21 | 1979-02-08 | Boehringer Sohn Ingelheim | Neue substituierte 1-acyl-piperidino- bzw. -piperazino-4h-s-triazolo eckige klammer auf 3,4c eckige klammer zu thieno eckige klammer auf 2,3e eckige klammer zu 1,4- diazepine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen |
| US4183912A (en) * | 1978-01-16 | 1980-01-15 | American Home Products Corporation | Inhalation therapy for relieving bronchial spasm using quaternary salts of promethazine |
| DE2830782A1 (de) * | 1978-07-13 | 1980-01-24 | Boehringer Sohn Ingelheim | Neue substituierte 4h-s-triazolo eckige klammer auf 3,4c eckige klammer zu thieno eckige klammer auf 2,3e eckige klammer zu 1,4-diazepine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen |
| JPS6045518A (ja) * | 1983-08-22 | 1985-03-12 | Takeda Chem Ind Ltd | 抗シヨツク剤 |
| US4540709A (en) * | 1983-10-13 | 1985-09-10 | Merck & Co., Inc. | Method for treatment of diseases mediated by PAF using 5-allyl-2-(3,4-Dimethoxyphenyl)-3a,α-methoxy-3-methyl-2,3,3a,6-tetrahydro-6-oxobenzofuran |
| US4595693A (en) * | 1984-06-04 | 1986-06-17 | Merck & Co., Inc. | Method of use of 2,5-diaryl tetrahydrofurans and analogs thereof as PAF-antagonists |
| GB8418424D0 (en) * | 1984-07-19 | 1984-08-22 | Scras | Inhibition of platelets aggregation |
| DE3435973A1 (de) * | 1984-10-01 | 1986-04-10 | Boehringer Ingelheim KG, 6507 Ingelheim | Diazepine enthaltende pharmazeutische zusammensetzungen mit paf-antagonistischer wirkung |
| DE3502392A1 (de) * | 1985-01-25 | 1986-07-31 | Boehringer Ingelheim KG, 6507 Ingelheim | Neue thieno-triazolo-1,4-diazepino-2- carbonsaeureamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen |
| EP0230942B1 (de) * | 1986-01-21 | 1992-04-29 | Boehringer Ingelheim Kg | Thieno-1,4-diazepine |
| PH30676A (en) * | 1986-07-22 | 1997-09-16 | Boehringer Ingelhein Kg | Hetrazepine compounds which have useful pharmaceutical utility |
| JPS63225373A (ja) * | 1986-07-24 | 1988-09-20 | Sumitomo Pharmaceut Co Ltd | 新規チアゾリジン−4−オン誘導体およびその酸付加塩 |
| YU136287A (en) * | 1986-07-25 | 1990-06-30 | Boehringer Kg | Process for preparing new 1,4 benzodiazepines |
| DE3710921C2 (de) * | 1986-10-21 | 1996-09-26 | Korth Ruth | Verwendung der Gingkolide BN 52020, BN 52021 und BN 52063 zur Behandlung von Arteriosklerose |
| DE3735524C2 (de) * | 1986-10-21 | 1996-07-11 | Korth Ruth Maria | Verfahren zur Bestimmung des paf-Acether- oder Peak X-Gehaltes von Blut |
| DE3716004A1 (de) * | 1987-05-13 | 1988-11-24 | Bischof Hubert | Sicherheitsfolie, deren verwendung und mit dieser hergestelltes sicherheitsglas |
| DE3735525C2 (de) * | 1987-10-20 | 1997-02-20 | Korth Ruth Maria | Verfahren zur Bestimmung der Wirksamkeit von paf-Acether-Rezeptor-Antagonisten |
| DE4244265C2 (de) * | 1992-12-28 | 1999-08-12 | Korth Ruth Maria | Verwendung von Paf-Antagonisten gegen die neue Ausbildung von Paf-Bindungsstellen auf endothelialen Zellen zur Behandlung oder Vorbeugung des Hyperinsulinismus |
| GB8725871D0 (en) * | 1987-11-04 | 1987-12-09 | Scras | Ginkgolide derivatives |
| DE8716044U1 (de) * | 1987-12-04 | 1988-03-24 | Lewitz, Reinwald, 3100 Celle | Einbau-Häng-Globus |
| US5334592A (en) * | 1988-04-27 | 1994-08-02 | Schering Corporation | Certain PAF antagonist antihistamine combinations and methods |
| US5147864A (en) * | 1988-12-19 | 1992-09-15 | American Cyanamid Company | Bis-arylphosphate ester antagonists of platelet activating factor |
| DE69027992D1 (de) * | 1989-05-05 | 1996-09-05 | North Sydney Area Health Serv | Steigerung der fruchtbarkeit |
| IT1238684B (it) * | 1990-02-09 | 1993-09-01 | Indena Spa | Derivati del bilobalide,loro usi e formulazioni che li contegono |
| ATE195653T1 (de) * | 1990-06-06 | 2000-09-15 | Ruth Korth | Behandlung von erkrankungen mit paf-antagonisten und verfahren zur bestimmung deren wirksamkeit |
-
1991
- 1991-11-04 AT AT91118745T patent/ATE221779T1/de not_active IP Right Cessation
- 1991-11-04 EP EP91118745A patent/EP0540767B9/de not_active Expired - Lifetime
- 1991-11-04 ES ES91118745T patent/ES2181665T3/es not_active Expired - Lifetime
- 1991-11-04 DE DE69133083T patent/DE69133083C5/de not_active Expired - Lifetime
- 1991-11-04 DE DE0540767T patent/DE540767T1/de active Pending
-
1992
- 1992-10-28 US US07/969,674 patent/US5346894A/en not_active Expired - Fee Related
- 1992-11-04 JP JP4319511A patent/JPH06305981A/ja active Pending
-
1994
- 1994-06-17 US US08/261,765 patent/US5605927A/en not_active Expired - Lifetime
-
1996
- 1996-12-09 US US08/761,938 patent/US5852052A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2181665T3 (es) | 2003-03-01 |
| DE69133083T2 (de) | 2003-05-08 |
| DE69133083D1 (de) | 2002-09-12 |
| US5852052A (en) | 1998-12-22 |
| EP0540767B9 (de) | 2004-12-22 |
| EP0540767A1 (de) | 1993-05-12 |
| US5605927A (en) | 1997-02-25 |
| US5346894A (en) | 1994-09-13 |
| EP0540767B1 (de) | 2002-08-07 |
| DE540767T1 (de) | 2001-10-25 |
| JPH06305981A (ja) | 1994-11-01 |
| DE69133083C5 (de) | 2007-05-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0540767 Country of ref document: EP |
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| REN | Ceased due to non-payment of the annual fee |