ES2141787T3 - Derivados de la 1,2,3,4-tetrahidro-9-acridinamina. - Google Patents
Derivados de la 1,2,3,4-tetrahidro-9-acridinamina.Info
- Publication number
- ES2141787T3 ES2141787T3 ES94112223T ES94112223T ES2141787T3 ES 2141787 T3 ES2141787 T3 ES 2141787T3 ES 94112223 T ES94112223 T ES 94112223T ES 94112223 T ES94112223 T ES 94112223T ES 2141787 T3 ES2141787 T3 ES 2141787T3
- Authority
- ES
- Spain
- Prior art keywords
- acridinamine
- tetrahydro
- derivatives
- agents
- cerebral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/08—Nitrogen atoms
- C07D219/10—Nitrogen atoms attached in position 9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Abstract
SE PRESENTAN NUEVAS PRODROGAS O DERIVADOS DE LA 1,2,3,4-TETRAHIDRO9-ACRIDINAMINA DE LA FORMULA I ASI COMO METODOS PARA LA PREPARACION DE LOS MISMOS Y COMPOSICIONES FARMACEUTICAS OBTENIDAS A PARTIR DE LOS MISMOS, QUE SON UTILES COMO AGENTES ANALGESICOS PARA EL TRATAMIENTO DEL DOLOR, COMO AYUDA PARA EL SUEÑO Y COMO AGENTES PARA EL TRATAMIENTO DE SINTOMAS PARA LA DEMENCIA SENIL, LA ENFERMEDAD DE ALZHEIMER, EL BAILE DE SANVITO, MANIAS O CONDICIONES SIMILARES DE INSUFICIENCIA CEREBRAL QUE SE CARACTERIZAN POR UN DESCENSO DE LA PRODUCCION DE LA ACETILCOLEINA CEREBRAL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/387,722 US4999430A (en) | 1989-07-31 | 1989-07-31 | Derivatives of 1,2,3,4-tetrahydro-9-acrisinamine |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2141787T3 true ES2141787T3 (es) | 2000-04-01 |
Family
ID=23531113
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90114586T Expired - Lifetime ES2068955T3 (es) | 1989-07-31 | 1990-07-30 | Derivados de 1,2,3,4-tetrahidro-9-acridinamina. |
ES94112223T Expired - Lifetime ES2141787T3 (es) | 1989-07-31 | 1990-07-30 | Derivados de la 1,2,3,4-tetrahidro-9-acridinamina. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90114586T Expired - Lifetime ES2068955T3 (es) | 1989-07-31 | 1990-07-30 | Derivados de 1,2,3,4-tetrahidro-9-acridinamina. |
Country Status (17)
Country | Link |
---|---|
US (1) | US4999430A (es) |
EP (2) | EP0628548B1 (es) |
JP (1) | JP2930245B2 (es) |
KR (1) | KR910002802A (es) |
AT (2) | ATE119885T1 (es) |
AU (1) | AU5994590A (es) |
CA (1) | CA2022297C (es) |
DE (2) | DE69033369T2 (es) |
DK (2) | DK0411534T3 (es) |
ES (2) | ES2068955T3 (es) |
FI (1) | FI903752A0 (es) |
GR (1) | GR3032539T3 (es) |
IE (1) | IE66823B1 (es) |
NO (1) | NO903359L (es) |
NZ (1) | NZ234672A (es) |
PT (1) | PT94849A (es) |
ZA (1) | ZA905978B (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL85741A (en) * | 1987-03-17 | 1996-05-14 | Hoechst Roussel Pharma | Transformed Tetra-Hydroacridines Process for their preparation and pharmaceutical preparations containing A-amino-Tetra-Transformed Hydroacridines |
FR2640508B1 (fr) * | 1988-12-19 | 1994-07-01 | Dietlin Francois | Nouvelles compositions et nouveaux produits pharmaceutiques assurant la regeneration de leucocytes et leur emploi pour le traitement du syndrome immuno-deficitaire |
JP2546919B2 (ja) * | 1989-11-08 | 1996-10-23 | 三菱化学株式会社 | 9ーアシルアミノテトラヒドロアクリジン誘導体 |
CA2029497C (en) * | 1989-11-08 | 2002-06-04 | Kunihiro Ninomiya (Deceased) | 4-acylaminopyridine derivative |
US5179100A (en) * | 1992-03-09 | 1993-01-12 | Hoechst-Roussel Pharmaceuticals Inc. | 4,5-dihydropyrazolo[3,4-a]acridines |
US5422350A (en) * | 1992-09-10 | 1995-06-06 | Warner-Lambert Company | Nitrogen substituted acridine and cytochrome P450 inhibitors and methods of use |
US5466696A (en) * | 1992-09-10 | 1995-11-14 | Warner Lambert Company | Tacrine and cytochrome P450 oxidase inhibitors and methods of use |
HU213107B (en) * | 1994-02-23 | 1997-02-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing acetic acid derivatives and pharmaceutical compositions containing them |
GB9716879D0 (en) * | 1997-08-08 | 1997-10-15 | Shire Int Licensing Bv | Treatment of attention deficit disorders |
US6218383B1 (en) | 1998-08-07 | 2001-04-17 | Targacept, Inc. | Pharmaceutical compositions for the prevention and treatment of central nervous system disorders |
ES2168926B1 (es) * | 1999-12-14 | 2003-10-16 | Prous Science S A | Derivados de ciclopenta- ciclohexa- y ciclohepta (b)quinoleina, procedimiento para su fabricacion, utilizacion y composicion farmaceutica correspondiente. |
US20080045500A1 (en) * | 2004-07-01 | 2008-02-21 | Eisai R&D Management Co., Ltd. | Nerve Regeneration Stimulator |
CN1315810C (zh) * | 2004-08-30 | 2007-05-16 | 北京理工大学 | 哌嗪桥联他克林双体衍生物及其合成方法 |
US20080188510A1 (en) * | 2005-05-23 | 2008-08-07 | Eisai R & D Management Co., Ltd. | Novel methods using zonisamide |
JP2013513588A (ja) * | 2009-12-11 | 2013-04-22 | ジーンコード エーエス | Gdnfファミリーリガンド(gfl)のミメティックまたはretシグナル経路活性化因子を用いた、神経系細胞の生存を容易にするための方法 |
CA2789014C (en) | 2010-02-09 | 2019-01-15 | Michela Gallagher | Methods and compositions for improving cognitive function |
JP6440625B2 (ja) | 2012-11-14 | 2018-12-19 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 精神分裂病を処置するための方法および組成物 |
WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
CA2904767C (en) | 2013-03-15 | 2022-06-21 | Agenebio, Inc. | Methods and compositions for improving cognitive function |
WO2016191288A1 (en) | 2015-05-22 | 2016-12-01 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4985430A (en) * | 1987-12-03 | 1991-01-15 | Mitsubishi Kasei Corporation | 9-acylamino-tetrahydroacridine derivatives and memory enhancing agent containing said derivative as active ingredient |
-
1989
- 1989-07-31 US US07/387,722 patent/US4999430A/en not_active Expired - Lifetime
-
1990
- 1990-07-27 NZ NZ234672A patent/NZ234672A/xx unknown
- 1990-07-27 AU AU59945/90A patent/AU5994590A/en not_active Abandoned
- 1990-07-27 FI FI903752A patent/FI903752A0/fi not_active Application Discontinuation
- 1990-07-30 NO NO90903359A patent/NO903359L/no unknown
- 1990-07-30 ES ES90114586T patent/ES2068955T3/es not_active Expired - Lifetime
- 1990-07-30 DK DK90114586.2T patent/DK0411534T3/da active
- 1990-07-30 DE DE69033369T patent/DE69033369T2/de not_active Expired - Fee Related
- 1990-07-30 IE IE275190A patent/IE66823B1/en not_active IP Right Cessation
- 1990-07-30 DK DK94112223T patent/DK0628548T3/da active
- 1990-07-30 EP EP94112223A patent/EP0628548B1/en not_active Expired - Lifetime
- 1990-07-30 PT PT94849A patent/PT94849A/pt not_active Application Discontinuation
- 1990-07-30 DE DE69017789T patent/DE69017789T2/de not_active Expired - Fee Related
- 1990-07-30 KR KR1019900011578A patent/KR910002802A/ko not_active Application Discontinuation
- 1990-07-30 ZA ZA905978A patent/ZA905978B/xx unknown
- 1990-07-30 JP JP2199361A patent/JP2930245B2/ja not_active Expired - Fee Related
- 1990-07-30 ES ES94112223T patent/ES2141787T3/es not_active Expired - Lifetime
- 1990-07-30 EP EP90114586A patent/EP0411534B1/en not_active Expired - Lifetime
- 1990-07-30 AT AT90114586T patent/ATE119885T1/de not_active IP Right Cessation
- 1990-07-30 CA CA002022297A patent/CA2022297C/en not_active Expired - Fee Related
- 1990-07-30 AT AT94112223T patent/ATE186908T1/de not_active IP Right Cessation
-
2000
- 2000-02-02 GR GR20000400235T patent/GR3032539T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0628548A1 (en) | 1994-12-14 |
AU5994590A (en) | 1991-01-31 |
NO903359L (no) | 1991-02-01 |
JP2930245B2 (ja) | 1999-08-03 |
DE69017789T2 (de) | 1995-07-13 |
JPH0366670A (ja) | 1991-03-22 |
US4999430A (en) | 1991-03-12 |
IE902751A1 (en) | 1991-02-27 |
NO903359D0 (no) | 1990-07-30 |
DK0628548T3 (da) | 2000-05-08 |
EP0411534A3 (en) | 1991-06-05 |
DK0411534T3 (da) | 1995-07-24 |
FI903752A0 (fi) | 1990-07-27 |
EP0411534B1 (en) | 1995-03-15 |
DE69017789D1 (de) | 1995-04-20 |
DE69033369D1 (de) | 1999-12-30 |
GR3032539T3 (en) | 2000-05-31 |
DE69033369T2 (de) | 2000-05-11 |
NZ234672A (en) | 1991-11-26 |
ES2068955T3 (es) | 1995-05-01 |
IE66823B1 (en) | 1996-02-07 |
PT94849A (pt) | 1991-04-18 |
ATE186908T1 (de) | 1999-12-15 |
KR910002802A (ko) | 1991-02-26 |
CA2022297C (en) | 2001-09-18 |
ZA905978B (en) | 1992-04-29 |
EP0411534A2 (en) | 1991-02-06 |
ATE119885T1 (de) | 1995-04-15 |
EP0628548B1 (en) | 1999-11-24 |
CA2022297A1 (en) | 1991-02-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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