ATE119885T1 - 1,2,3,4-tetrahydro-9-akridinaminderivate. - Google Patents

1,2,3,4-tetrahydro-9-akridinaminderivate.

Info

Publication number
ATE119885T1
ATE119885T1 AT90114586T AT90114586T ATE119885T1 AT E119885 T1 ATE119885 T1 AT E119885T1 AT 90114586 T AT90114586 T AT 90114586T AT 90114586 T AT90114586 T AT 90114586T AT E119885 T1 ATE119885 T1 AT E119885T1
Authority
AT
Austria
Prior art keywords
tetrahydro
derivatives
acridiminine
agents
cerebral
Prior art date
Application number
AT90114586T
Other languages
English (en)
Inventor
Colin Granger
Moos Walter Hamilton
Jeffrey Alan Kester
Anthony Jerome Thomas
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of ATE119885T1 publication Critical patent/ATE119885T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Water Treatment By Electricity Or Magnetism (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT90114586T 1989-07-31 1990-07-30 1,2,3,4-tetrahydro-9-akridinaminderivate. ATE119885T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/387,722 US4999430A (en) 1989-07-31 1989-07-31 Derivatives of 1,2,3,4-tetrahydro-9-acrisinamine

Publications (1)

Publication Number Publication Date
ATE119885T1 true ATE119885T1 (de) 1995-04-15

Family

ID=23531113

Family Applications (2)

Application Number Title Priority Date Filing Date
AT90114586T ATE119885T1 (de) 1989-07-31 1990-07-30 1,2,3,4-tetrahydro-9-akridinaminderivate.
AT94112223T ATE186908T1 (de) 1989-07-31 1990-07-30 1,2,3,4-tetrahydro-9-akridinamine-derivate

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT94112223T ATE186908T1 (de) 1989-07-31 1990-07-30 1,2,3,4-tetrahydro-9-akridinamine-derivate

Country Status (17)

Country Link
US (1) US4999430A (de)
EP (2) EP0411534B1 (de)
JP (1) JP2930245B2 (de)
KR (1) KR910002802A (de)
AT (2) ATE119885T1 (de)
AU (1) AU5994590A (de)
CA (1) CA2022297C (de)
DE (2) DE69033369T2 (de)
DK (2) DK0411534T3 (de)
ES (2) ES2068955T3 (de)
FI (1) FI903752A0 (de)
GR (1) GR3032539T3 (de)
IE (1) IE66823B1 (de)
NO (1) NO903359L (de)
NZ (1) NZ234672A (de)
PT (1) PT94849A (de)
ZA (1) ZA905978B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI91401C (fi) * 1987-03-17 1994-06-27 Hoechst Roussel Pharma Menetelmä terapeuttisesti aktiivisten substituoitujen 9-aminotetrahydroakriinien ja niille läheisten yhdisteiden valmistamiseksi
FR2640508B1 (fr) * 1988-12-19 1994-07-01 Dietlin Francois Nouvelles compositions et nouveaux produits pharmaceutiques assurant la regeneration de leucocytes et leur emploi pour le traitement du syndrome immuno-deficitaire
CA2029497C (en) * 1989-11-08 2002-06-04 Kunihiro Ninomiya (Deceased) 4-acylaminopyridine derivative
JP2546919B2 (ja) * 1989-11-08 1996-10-23 三菱化学株式会社 ９ーアシルアミノテトラヒドロアクリジン誘導体
US5179100A (en) * 1992-03-09 1993-01-12 Hoechst-Roussel Pharmaceuticals Inc. 4,5-dihydropyrazolo[3,4-a]acridines
US5422350A (en) * 1992-09-10 1995-06-06 Warner-Lambert Company Nitrogen substituted acridine and cytochrome P450 inhibitors and methods of use
US5466696A (en) * 1992-09-10 1995-11-14 Warner Lambert Company Tacrine and cytochrome P450 oxidase inhibitors and methods of use
HU213107B (en) * 1994-02-23 1997-02-28 Egyt Gyogyszervegyeszeti Gyar Process for producing acetic acid derivatives and pharmaceutical compositions containing them
GB9716879D0 (en) * 1997-08-08 1997-10-15 Shire Int Licensing Bv Treatment of attention deficit disorders
US6218383B1 (en) 1998-08-07 2001-04-17 Targacept, Inc. Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
ES2168926B1 (es) * 1999-12-14 2003-10-16 Prous Science S A Derivados de ciclopenta- ciclohexa- y ciclohepta (b)quinoleina, procedimiento para su fabricacion, utilizacion y composicion farmaceutica correspondiente.
WO2006004201A1 (ja) * 2004-07-01 2006-01-12 Eisai R & D Management Co., Ltd. 神経再生促進剤
CN1315810C (zh) * 2004-08-30 2007-05-16 北京理工大学 哌嗪桥联他克林双体衍生物及其合成方法
US20080188510A1 (en) * 2005-05-23 2008-08-07 Eisai R & D Management Co., Ltd. Novel methods using zonisamide
MX2012006580A (es) * 2009-12-11 2012-09-28 Genecode As Metodo para facilitar la sobrevivencia de celulas neurales usando mimeticos de ligandos (gfl) de la familia gdnf o activadores de la ruta de señalizacion de ret.
EP2533645B1 (de) 2010-02-09 2016-07-27 The Johns Hopkins University Verfahren und zusammensetzungen zur verbesserung von kognitiven funktionen
EP2919788A4 (de) 2012-11-14 2016-05-25 Univ Johns Hopkins Verfahren und zusammensetzungen zur behandlung von schizophrenie
DK2968220T3 (da) 2013-03-15 2021-06-14 Agenebio Inc Fremgangsmåder og sammensætninger til forbedring af kognitiv funktion
EP2968237A4 (de) 2013-03-15 2016-08-31 Univ Johns Hopkins Verfahren und zusammensetzungen zur verbesserung der kognitiven funktion
BR112017025031B1 (pt) 2015-05-22 2023-03-21 Agenebio, Inc Composições farmacêuticas de liberação prolongada de levetiracetam

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4985430A (en) * 1987-12-03 1991-01-15 Mitsubishi Kasei Corporation 9-acylamino-tetrahydroacridine derivatives and memory enhancing agent containing said derivative as active ingredient

Also Published As

Publication number Publication date
EP0628548A1 (de) 1994-12-14
DK0628548T3 (da) 2000-05-08
DE69017789D1 (de) 1995-04-20
JPH0366670A (ja) 1991-03-22
KR910002802A (ko) 1991-02-26
ES2068955T3 (es) 1995-05-01
EP0411534A3 (en) 1991-06-05
NO903359L (no) 1991-02-01
NZ234672A (en) 1991-11-26
EP0628548B1 (de) 1999-11-24
AU5994590A (en) 1991-01-31
EP0411534B1 (de) 1995-03-15
DE69033369D1 (de) 1999-12-30
CA2022297C (en) 2001-09-18
PT94849A (pt) 1991-04-18
CA2022297A1 (en) 1991-02-01
ZA905978B (en) 1992-04-29
ATE186908T1 (de) 1999-12-15
FI903752A0 (fi) 1990-07-27
US4999430A (en) 1991-03-12
IE66823B1 (en) 1996-02-07
IE902751A1 (en) 1991-02-27
DE69033369T2 (de) 2000-05-11
EP0411534A2 (de) 1991-02-06
GR3032539T3 (en) 2000-05-31
DE69017789T2 (de) 1995-07-13
JP2930245B2 (ja) 1999-08-03
NO903359D0 (no) 1990-07-30
ES2141787T3 (es) 2000-04-01
DK0411534T3 (da) 1995-07-24

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee