PT3409278T - Inibidores de proteína cinase heterocíclicos - Google Patents

Inibidores de proteína cinase heterocíclicos

Info

Publication number
PT3409278T
PT3409278T PT181628538T PT18162853T PT3409278T PT 3409278 T PT3409278 T PT 3409278T PT 181628538 T PT181628538 T PT 181628538T PT 18162853 T PT18162853 T PT 18162853T PT 3409278 T PT3409278 T PT 3409278T
Authority
PT
Portugal
Prior art keywords
protein kinase
kinase inhibitors
heterocyclic
heterocyclic protein
inhibitors
Prior art date
Application number
PT181628538T
Other languages
English (en)
Portuguese (pt)
Original Assignee
Sumitomo Dainippon Pharma Oncology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Dainippon Pharma Oncology Inc filed Critical Sumitomo Dainippon Pharma Oncology Inc
Publication of PT3409278T publication Critical patent/PT3409278T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT181628538T 2011-07-21 2012-07-20 Inibidores de proteína cinase heterocíclicos PT3409278T (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161510207P 2011-07-21 2011-07-21
US201161632834P 2011-07-21 2011-07-21
US201261632826P 2012-03-01 2012-03-01
US201261608028P 2012-03-07 2012-03-07

Publications (1)

Publication Number Publication Date
PT3409278T true PT3409278T (pt) 2020-12-18

Family

ID=47558512

Family Applications (1)

Application Number Title Priority Date Filing Date
PT181628538T PT3409278T (pt) 2011-07-21 2012-07-20 Inibidores de proteína cinase heterocíclicos

Country Status (10)

Country Link
US (7) US9416132B2 (enExample)
EP (3) EP3409278B8 (enExample)
JP (1) JP6105578B2 (enExample)
CY (1) CY1123626T1 (enExample)
DK (2) DK2734205T3 (enExample)
ES (2) ES2671748T3 (enExample)
HU (1) HUE052198T2 (enExample)
PL (1) PL3409278T3 (enExample)
PT (1) PT3409278T (enExample)
WO (1) WO2013013188A1 (enExample)

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US11028351B2 (en) 2018-06-27 2021-06-08 Henkel IP & Holding GmbH Unit dose detergent packs with anti-yellowing and anti-efflorescence formulations
HUE072069T2 (hu) 2019-02-12 2025-10-28 Sumitomo Pharma America Inc 2-((1R,4R)-4-((3-(3-(trifluormetil)fenil)imidazo[1,2- b]piridazin-6-il)amino)ciklohexil)propán-2-ol sósavas sójának kristályos formája
IL296921B1 (en) * 2020-04-15 2026-08-01 Pyramid Biosciences Inc Methods for preparing receptor tyrosine kinase inhibitors
CN112430632B (zh) * 2020-11-18 2022-09-13 上海合全药物研发有限公司 2-((反式)-4-氨基环己烷基)异丙醇的制备方法
EP4289847A4 (en) * 2021-02-08 2025-01-01 Hangzhou Biosun Pharmaceutical Co., Ltd. PIM KINASE INHIBITOR
US20250042918A1 (en) * 2021-12-01 2025-02-06 Fundación Del Sector Públlco Estatal Centro Nacional De Investigaciones Oncológicas Carlos III Compounds
CN116262753A (zh) * 2021-12-13 2023-06-16 杭州邦顺制药有限公司 一种新颖的pim激酶抑制剂
AU2023372386A1 (en) 2022-10-31 2025-05-08 Sumitomo Pharma America, Inc. Pim1 inhibitor for treating myeloproliferative neoplasms
CN116836168B (zh) * 2023-05-24 2026-01-02 浙江大学 7-二氟甲基-5-芳基吡唑并嘧啶类化合物及制备与应用

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